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Spinous process plate fixation for cervical spinal fusion after spinal trauma:two case reports

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Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2013年第9期14卷 855-858页

作者： Hiroki HIRABAYASHI Jun TAKAHASHI Hiroyuki HASHIDATE Nobuhide OGIHARA Keijiro MUKAIYAMA Shugo KURAISHI masayuki shimizu Hiroyuki NAKAGAWA Renzo MATSUE Hiroyuki KATO Department of Orthopedic Surgery Shinshu University School of Medicine

Posterior cervical fixation with various forms of instrumentation has been used for reconstruction in cases of traumatic disorders and degenerative or tumor-related dysfunction of the cervical spine. Recently, posterior plate and rod techniques using lateral mass screws or pedicle screws have been reported to show excellent fusion rates (Xu et al.,2010).

关键词：病例报告脊柱融合脊髓损伤颈椎椎弓根螺钉钢板功能障碍外伤性

Disruption of neuronal actin barrier promotes the entry of disease-implicated proteins to exacerbate amyotrophic lateral sclerosis pathology

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Neural Regeneration Research 2025年第9期20卷 2589-2590页

作者： Mikio shimizu Tatsusada Okuno Department of Neurology Osaka University Graduate School of MedicineSuitaJapan Department of Neurology Osaka General Medical CenterOsakaJapan

Amyotrophic lateral sclerosis(ALS)is a devastating neurological disease characterized by the accumulation of aberrant proteins in motor neurons of the brain and spinal *** with ALS develop skeletal muscle weakness,resulting in death from respiratory paralysis,which usually occurs 2-4 years after clinical onset(Goutman et al.,2022).

关键词： paralysis sclerosis

21世纪的日本哲学:战后和辻哲郎的思想变迁

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浙江树人大学学报 2011年第3期11卷 68-73页

作者：清水正之任萍日本圣学院大学琦玉362—8585

和辻哲郎是现代日本哲学的代表人物之一。最近新的实践哲学的发展动向之一是关注如何用哲学概念去理解现实的日常关系性,深入思考日语与哲学的关系,这与和辻哲郎的哲学、伦理学密切相关。和辻认为只有用日语思考,才能重新发现日本哲学... 详细信息

和辻哲郎是现代日本哲学的代表人物之一。最近新的实践哲学的发展动向之一是关注如何用哲学概念去理解现实的日常关系性,深入思考日语与哲学的关系,这与和辻哲郎的哲学、伦理学密切相关。和辻认为只有用日语思考,才能重新发现日本哲学的可能性。认为"信赖"是人际关系中最基本的感情。人们的"真实"表现为对待信赖的态度,这是人们存在的基本形态。以战败为契机,和辻的伦理学体系发生了很大变化,重新回归"文化哲学"的原点。在"日本哲学"状况发生很大变化的今天,和辻思想中的许多内容值得我们反思和继承。

关键词：日本哲学战后和辻哲郎

Relative importance of tidal flats and artificial habitats for two spoonbill species and related interspecific differences

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Avian Research 2023年第3期14卷 317-325页

作者： Takehiko shimizu masayuki Senzaki Yuichiro Fujioka Satoquo Seino School of Interdisciplinary Science and Innovation Kyushu UniversityMotooka 744Nishi-kuFukuoka819-0395Japan Graduate School of Environmental Science Hokkaido UniversityKita 10-jo Nishi 5-chome Kita-kuSapporoHokkaido060-0810Japan Faculty of Environmental Earth Science Hokkaido UniversityKita 10-jo Nishi 5-chome Kita-kuSapporoHokkaido060-0810Japan Faculty of Social and Cultural Studies Kyushu UniversityMotooka 744Nishi-kuFukuoka819-0395Japan Faculty of Engineering Kyushu UniversityMotooka 744Nishi-kuFukuoka819-0395Japan

Artificial/seminatural environments,such as aquacultural ponds,saltpans,and croplands,have recently been acknowledged as important habitats for coastal *** coastal waterbirds tend to use artificial habitats around tidal flats as roosting sites during high-tide,it remains unclear whether the importance of surrounding habitats relative to tidal flats varies among landscape types,seasons,species,or tidal *** Black-faced Spoonbill(Platalea minor)and Eurasian Spoonbill(***)are two closely related sympatric species in East Asia with narrow and wide distribution ranges and habitat requirements,*** therefore expect that both species will use surrounding artificial habitats across seasons at high tides,but Blackfaced Spoonbills will use them less frequently than Eurasian ***,we address these hypotheses in the Imazu tidal flat and its surrounding environments in southern *** investigated the habitat use and behavioral patterns of both species through route and behavioral surveys during the fall migration and wintering seasons in *** found that both species used surrounding habitats including artificial ones more frequently than the tidal flat regardless of the tidal condition or season,but spoonbills used these habitats more frequently in winter than in *** also found that Eurasian Spoonbills foraged in surrounding artificial habitats more frequently than Black-faced *** results not only demonstrate how coastal waterbirds exploit surrounding habitats relative to tidal flats but also suggest that the importance of surrounding habitats varies among species and *** study thus emphasizes that valuing and managing surrounding habitats in addition to tidal flats are key to conserving globally declining waterbirds.

关键词： Artificial habitat Behavior Black-faced Spoonbill Eurasian Spoonbill Habitat use Surrounding environment Species distribution model Tidal flat

Comparison of corneal biomechanical properties in normal tension glaucoma patients with different visual field progression speed

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International Journal of Ophthalmology(English edition) 2016年第7期9卷 973-978页

作者： Ying Hong Nobuyuki Shoji Tetsuya Morita Kazunori Hirasawa Kazuhiro Matsumura masayuki Kasahara Kimiya shimizu Department of Ophthalmology Peking University Third Hospital Key Laboratory of Vision Loss and RestorationMinistry of Education Beijing 100191 China Department of Rehabilitation Orthoptics and Visual Science Course Kitasato University School of Allied Health Sciences Sagamihara City 252-0373 Japan Department of Ophthalmology Kitasato University Hospital Sagamihara City 252-0373 Japan Kitasato University Sagamihara City 252-0373 Japan

AIM：To compare the corneal biomechanical properties difference by ocular response analyzer（ORA） in normal tension glaucoma（NTG） patients with different visual field（VF） progression speed. METHODS：NTG patients with well-controlled Goldmann applanation tonometer（GAT） who routinely consulted Kitasato University Hospital Glaucoma Department between January 2010 and February 2014 were *** and ORA parameters including corneal compensated intraocular pressure（lOPcc）,Goldmann estimated intraocular pressure（lOPg）,corneal hysteresis（CH）,corneal resistance factor（CRF） were *** was tested by Swedish interactive threshold algorithm（SITA）-standard 30-2 *** patients underwent VF measurement regularly and GAT did not exceed 15 mm Hg at any time during the 3y follow *** were divided into four groups according to VF change over 3y,and ORA findings were compared between the upper 25th percentile group（slow progression group） and the lower 25th percentile group（rapid progression group）.RESULTS：Eighty-two eyes of 56 patients were *** were 21 eyes（21 patients） each in rapid and slow progression groups ***,lOPcc,lOPg,CH,CRF were 12.1＋1.4 mm Hg,15.8±1.8 mm Hg,12.8±2.0 mm Hg,8.4±1.1 mm Hg,7.9±1.3 mm Hg respectively in rapid progression group and 11.5±1.3 mm Hg,13.5±2.1 mm Hg,11.2±1.6 mm Hg,9.3±1.1 mm Hg,8.2±0.9 mm Hg respectively in slow progression group（P=0.214,〈0.001,0.007,0.017,0.413,respectively）.In bivariate correlation analysis,lOPcc,lOPcc-GAT and CH were significant correlated with m△MD（r =-0.292,-0.312,0.228 respectively,P =0.008,0.004,0.039 respectively）.CONCLUSION：Relatively rapid VF progression occurred in NTG patients whose lOPcc are rather high,CH are rather low and the difference between lOPcc and GAT are relatively *** lOPcc and lower CH are associated with VF progression in NTG *** study suggests that GAT measures might underestimate the IOP in such patients.

关键词： ocular response analyzer intraocular pressure corneal biochemical properties visual field normal tension glaucoma

Peripheral portal vein-oriented non-dilated bile duct puncture for percutaneous transhepatic biliary drainage

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World Journal of Gastroenterology 2015年第44期21卷 12628-12634页

作者： Hiroaki shimizu Atsushi Kato Tsukasa Takayashiki Satoshi Kuboki masayuki Ohtsuka Hideyuki Yoshitomi Katsunori Furukawa Masaru Miyazaki Department of General Surgery Chiba University Graduate School of Medicine Chiba City

AIM: To evaluate the efficacy of peripheral portal vein(PV)-oriented non-dilated bile duct(BD) puncture for percutaneous transhepatic biliary drainage(PTBD).METHODS: Thirty-five patients with non-dilated BDs underwent PTBD for the management of various biliary disorders, including benign bilioenteric anastomotic stricture(n = 24), BD stricture(n = 5) associated with iatrogenic BD injury, and postoperative biliary leakage(n = 6). Under ultrasonographic guidance, percutaneous transhepatic puncture using a 21-G needle was performed along the running course of the peripheral targeted non-dilated BD(preferably B6 for right-sided approach, and B3 for left-sided approach) or along the accompanying PV when the BD was not well visualized. This technique could provide an appropriate insertion angle of less than 30° between the puncture needle and BD running course. The puncture needle was then advanced slightly beyond the accompanying PV. The needle tip was moved slightly backward while injecting a small amount of contrast agent to obtain the BD image, followed by insertion of a 0.018-inch guide wire(GW). A drainage catheter was then placed usinga two-step GW method. RESULTS: PTBD was successful in 33(94.3%) of the 35 patients with non-dilated intrahepatic BDs. A rightsided approach was performed in 25 cases, while a left-sided approach was performed in 10 cases. In 31 patients, the first PTBD attempt proved successful. Four cases required a second attempt a few days later to place a drainage catheter. PTBD was successful in two cases, but the second attempt also failed in the other two cases, probably due to poor breath-holding ability. Although most patients(n = 26) had been experiencing cholangitis with fever(including septic condition in 8 cases) before PTBD, only 5(14.3%) patients encountered PTBD procedure-related complications, such as transient hemobilia and cholangitis. No major complications such as bilioarterial fistula or portal thrombosis were observed. There was

关键词： Percutaneous transhepatic biliary drainage Cholang

Inelastic constitutive equation of plasma-sprayed ceramic thermal barrier coatings

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Acta Metallurgica Sinica(English Letters) 2011年第2期24卷 161-168页

作者： masayuki ARAI Materials Science Research Laboratory Central Research Institute of Electric Power Industry

Ceramic thermal barrier coatings （TBCs） are a very important technology for protecting the hot parts of gas turbines （GTs） from a high-temperature environment. The coating stress generated in the operation of GTs brings cracking and peeling damage to the TBCs. Thus, it is necessary to evaluate precisely such coating stress in a TBC system. We have obtained a stress-strain curve for a freestanding ceramic coat specimen peeled from a TBC coated substrate by conducting the bending test. The test results have revealed that the ceramic coating deforms nonlinearly with the applied loading. In this study, an inelastic constitutive equation for the ceramic thermal barrier coatings deposited by APS is developed. The obtained results are as follows：（1） the micromechanics-based constitutive equation was formulated with micro crack density formed at splat boundary, and （2） it was shown that the numerical results for a nonlinearly deformed beam simulated by the developed constitutive equation agreed with the experimental results obtained by cantilever bending tests.

关键词： Inelastic constitutive equation Thermal barrier coating Gas turbine Micromechanics

Fluidization science,its development and future

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Particuology 2010年第6期8卷 514-524页

作者： masayuki Horio Department of Politics Ryukoku University RISTEX Japan Science and Technology AgencyKojimachi Square 5F3 Niban-choChiyoda-kuTokyo 102-0084Japan

By revisiting the three stage theory for the progress of science proposed by Taketani in 1942, the footmarks of fluidization research are examined. The bubbling and fast fluidization issues were emphasized so that the future offluidization research can be discussed among scientists and engineers in a wider perspective. The first cycle of fluidization research was started in the early 1940s by an initial stage of phenomenology. The second stage of structural studies was kicked off in the early 1950s with the introduction of the two phase theory. The third stage of essential studies occurred in the early 1960s in the form of bubble hydrodynamics. The second cycle, which confirmed the aforementioned three stages closed at the turn of the century, established a general understanding of suspension structures including agglomerating fluidization, bubbling, turbulent and fast fluidizations and pneumatic transport; also established powerful measurement and numerical simulation *** a general remark on science, technology and society issues the interactions between fluidization technology and science are revisited. Our future directions are discussed including the tasks in the third cycle, particularly in its phenomenology stage where strong motivation and intention are always necessary, in relation also to the green reforming of the present technology. A generalized definition of ＇fluidization＇ is proposed to extend fluidization principle into much wider scientific fields, which would be effective also for wider collaborations.

关键词： Historical development of fluidization Science and society Taketani's three step law Paradigm shift Fluid catalytic cracking Phase transition Bubbling bed Fast fluidization Cluster Future direction

Female hepatology:Favorable role of estrogen in chronic liver disease with hepatitis B virus infection

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World Journal of Gastroenterology 2007年第32期13卷 4295-4305页

作者： Ichiro shimizu Nao Kohno Katsuyoshi Tamaki masayuki Shono Hui-Wei Huang Jiang-Hong He Deng-Fu Yao Department of Digestive and Cardiovascular Medicine Institute of Health Biosciences University of Tokushima Graduate School Kuramoto-cho Tokushima 770-8503 Japan Support Center for Advanced Medical Sciences University of Tokushima Graduate School Kuramotocho Tokushima 770-8503 Japan Department of Physiology Faculty of Medicine Nantong University Nantong 226001 Jiangsu Province China Key Laboratory of Neuroregeneration of Jiangsu Province Nantong University Nantong 226001 Jiangsu Province China Research Center of Clinical Molecular Biology Affiliated Hospital Nantong University Nantong 226001 Jiangsu Province China

Chronic hepatitis B virus (HBV) infection is the most common cause of hepatic fibrosis and hepatocellular carcinoma (HCC),mainly as a result of chronic necroinflammatory liver disease. A characteristic feature of chronic hepatitis B infection,alcoholic liver disease and nonalcoholic fatty liver disease (NAFLD) is hepatic steatosis. Hepatic steatosis leads to an increase in lipid peroxidation in hepatocytes,which,in turn,activates hepatic stellate cells (HSCs). HSCs are the primary target cells for inflammatory and oxidative stimuli,and these cells produce extracellular matrix components. Chronic hepatitis B appears to progress more rapidly in males than in females,and NAFLD,cirrhosis and HCC are predominately diseases that tend to occur in men and postmenopausal women. Premenopausal women have lower hepatic iron stores and a decreased production of proinflammatory cytokines. Hepatic steatosis has been observed in aromatase-deficient mice,and has been shown to decrease in animals after estradiol treatment. Estradiol is a potent endogenous antioxidant which suppresses hepatic fibrosis in animal models,and attenuates induction of redox sensitive transcription factors,hepatocyte apoptosis and HSC activation by inhibiting a generation of reactive oxygen species in primary cultures. Variant estrogen receptors are expressed to a greater extent in male patients with chronic liver disease than in females. These lines of evidence suggest that the greater progression of hepatic fibrosis and HCC in men and postmenopausal women may be due,at least in part,to lower production of estradiol and a reduced response to the action of estradiol. A better understanding of the basic mechanisms underlying the sex-associated differences in hepatic fibrogenesis and carciogenesis may open up new avenues for the prevention and treatment of chronic liver disease.

关键词： Hepatic fibrosis Hepatocellular carcinoma Hepatic stellate cell Estradiol Estrogen receptor Oxidative stress Menopause Hepatic iron