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Poor Schedule Management Leads to Discontinuity of Medical Attendance among Patients Infected with HIV

Health 2019年第3期11卷 277-288页

作者： Fumiko Kagiura Megumi Shimada masayuki kakehashi Graduate School of Biomedical and Health Sciences Hiroshima University Hiroshima Japan Graduate School of Human Health Sciences Tokyo Metropolitan University Tokyo Japan

Dropout from medical attendance is a well-recognized issue among patients with human immunodeficiency virus (HIV) infection. We interviewed 23 HIV-positive patients and used text mining methods to analyse the risk factors for dropout. Fifteen patients continued medical attendance and eight patients dropped out of medical attendance. Categories were extracted from the interview data of the patients who continued medical attendance (i.e., the continuity group) and the patients who dropped out of medical care (i.e., the discontinuity group). Categories of the continuity group included needing to take a day off for medical attendance, scheduling each appointment, writing down medical appointments, being grateful for the medical care, and 12 additional categories. Categories of discontinuity group included forgetting the dates of medical appointments, not needing to get a day off for medical attendance, allowing aid for medical care to expire, and 10 additional categories. The discontinuity group had poorer schedule management than the continuity group, which caused them to forget their next medical appointments and delay the renewal of aid for medical care. Thus, medical staff may be able to prevent dropouts by ensuring that patients record the dates of their medical appointments.

关键词： Medical Attendance Human Immunodeficiency Virus Text Mining Face-to-Face Interview

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Qualitative Rural Indonesian Study of Diabetes Knowledge, Health Beliefs, and Behaviors in Type 2 Diabetes Patients

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Health 2019年第2期11卷 263-275页

作者： Nice Maylani Asril Keiji Tabuchi Miwako Tsunematsu Toshio Kobayashi masayuki kakehashi Department of Health Informatics Graduate School of Biomedical and Health Science Hiroshima University Hiroshima Japan Department of Education Faculty of Education Ganesha University of Education Bali Indonesia Department of Health Promotion and Development Science Graduate School of Biomedical and Health Science Hiroshima University Hiroshima Japan Department of General Internal Medicine Ishii Memorial Hospital Yamaguchi Japan

This study was aimed at understanding diabetes knowledge, health beliefs, and behaviors among type 2 diabetes patients in Balinese rural areas. The study used the Health Belief Model (HBM) in applied thematic analysis. It involved semi-structured focus groups with 20 patients (M = 49.95 years old, SD 6.7). Three themes formulated: poor diabetes knowledge, diabetes perceived as a life burden, and the factors affecting self-efficacy in practicing healthy lifestyle. The poor diabetes knowledge was due to traditional indigenous beliefs and low health literacy. The perception that diabetes is a life burden was related with physical and psychological condition. The factors affecting the self-efficacy were the perceived barriers and external influence. It is need to understand the traditional indigenous beliefs, burdens, and lacking internal intention as the modifying factors of health beliefs. This study suggests that the development of integrated health promotion of diabetes should consider the HBM’s modifying factors in rural areas.

关键词： Type 2 Diabetes Health Beliefs Health Behaviors Health Promotion Rural Areas

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日本广岛市脑卒中发病与气象条件关系

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中国公共卫生 2009年第5期25卷 606-607页

作者：汪宏莉韩延柏梯正之沈阳体育学院运动人体科学系沈阳110102 日本广岛大学大学院保健学研究科

目的探讨脑卒中发病与气象条件的关系。方法脑梗塞与脑出血病的病例由日本广岛市急救中心于2003年10月～2006年3月收集,气象数据由日本气象协会提供。日平均气温和气压分别定义为分组变量,采用泊松回归分析模型估计不同气温和气压条件... 详细信息

目的探讨脑卒中发病与气象条件的关系。方法脑梗塞与脑出血病的病例由日本广岛市急救中心于2003年10月～2006年3月收集,气象数据由日本气象协会提供。日平均气温和气压分别定义为分组变量,采用泊松回归分析模型估计不同气温和气压条件下脑梗塞与脑出血发病的危险度。结果在研究的892 d中,发生脑梗塞629例（男性占56.9%,女性占436.1%）;发生脑出血677例（男性占55.7%,女性占44.3%）。脑梗塞发病与气温呈U字形的关系,发病的危险度在21～24℃时最低,当气温低于15℃和高于30℃时,发病的危险度升高（P〈0.05）;脑梗塞发病的危险度在日平均气压高于1 015hPa时增大（P〈0.05）。脑出血发病的危险度随气温的升高而减小（P〈0.05）,随气压的升高而增大（P〈0.05）,并呈剂量-反应关系。结论脑梗塞和脑出血的发病与气温、气压有关。

关键词：脑卒中流行病学气象条件危险因素

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Prophylactic Pattern Scanning Laser Retinal Photocoagulation for Diabetic Retinopathy in Spontaneously Diabetic Torii Fatty Rats: Preliminary Experimental Results

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Journal of Diabetes Mellitus 2024年第3期14卷 153-165页

作者： Rina Takagi Yoshiaki Tanaka Tetsuya Hasegawa Masami Shinohara Yasushi Kageyama Tomohiko Sasase Machiko Shimmura-Tomita Akihiro kakehashi Toshikatsu Kaburaki Department of Ophthalmology Saitama Medical Center Jichi Medical University Saitama-shi Saitama-ken Japan Tokyo Animal & Diet Department CLEA Japan Inc. Tokyo Japan Biological/Pharmacological Research Laboratories Central Pharmaceutical Research Institute Japan Tobacco Inc. Takatsuki Osaka Japan

Research Background and Purpose: The number of diabetic patients is rapidly increasing, making it crucial to find methods to prevent diabetic retinopathy (DR), a leading cause of blindness. We investigated the effects of prophylactic pattern scanning laser retinal photocoagulation on DR development in Spontaneously Diabetic Torii (SDT) fatty rats as a new prevention approach. Methods: Photocoagulation was applied to the right eyes of 8-week-old Spontaneously Diabetic Torii (SDT) fatty rats, with the left eyes serving as untreated controls. Electroretinography at 9 and 39 weeks of age and pathological examinations, including immunohistochemistry for vascular endothelial growth factor and glial fibrillary acidic protein at 24 and 40 weeks of age, were performed on both eyes. Results: There were no significant differences in amplitude and prolongation of the OP waves between the right and left eyes in SDT fatty rats at 39 weeks of age. Similarly, no significant differences in pathology and immunohistochemistry were observed between the right and left eyes in SDT fatty rats at 24 and 40 weeks of age. Conclusion: Prophylactic pattern scanning retinal laser photocoagulation did not affect the development of diabetic retinopathy in SDT fatty rats.

关键词： Diabetes Pattern Scanning Laser Diabetic Retinopathy Spontaneously Diabetic Torii Fatty Rats Electroretinography

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Examination of in vivo mutagenicity of sodium arsenite and dimethylarsinic acid in gpt delta rats

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Journal of Environmental Sciences 2016年第11期28卷 125-130页

作者： Masaki Fujioka Min Gi Satoko Kawachi Kumiko Tatsumi Naomi Ishii Kenichiro Doi Anna kakehashi Hideki Wanibuchi Department of Molecular Pathology Osaka City University Graduate School of Medicine

Arsenic is a well-known human bladder and liver carcinogen, but its exact mechanism of carcinogenicity is not fully understood. Dimethylarsinic acid（DMAV） is a major urinary metabolite of sodium arsenite（i As~Ⅲ） and induces urinary bladder cancers in rats. DMAVand i As~Ⅲare negative in in vitro mutagenicity tests. However, their in vivo mutagenicities have not been determined. The purpose of present study is to evaluate the in vivo mutagenicities of DMAVand i As~Ⅲin rat urinary bladder epithelium and liver using gpt delta F344 ***-week old male gpt delta F344 rats were randomized into 3 groups and administered 0,92 mg/L DMAV, or 87 mg/L i As~Ⅲ（each 50 mg/L As） for 13 weeks in the drinking water. In the mutation assay, point mutations are detected in the gpt gene by 6-thioguanine selection（gpt assay） and deletion mutations are identified in the red/gam genes by Spi-selection（Spi-assay）. Results of the gpt and Spi-assays showed that DMAVand i As~Ⅲhad no effects on the mutant frequencies or mutation spectrum in urinary bladder epithelium or liver. These findings indicate that DMAVand i As~Ⅲare not mutagenic in urinary bladder epithelium or liver in rats.

关键词： Dimethylarsinic acid Sodium arsenite In vivo mutagenicity Urinary bladder epithelium gpt delta rat

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克山病之我见以及白肌病与信州心肌病(之一)

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中国地方病学杂志 2000年第2期19卷 150-152页

作者：梯保雄日本福冈县小郡市梯医院

目的探讨膳食与克山病发病的关系。方法回顾并分析了克山病有关文献，调查了克山病居民的膳食变化情况。结果１９５８年后，克山病病区人群出现了偏食，导致必需氨基酸摄入不足，引起了克山病发病；１９８０年后，病区居民生活水平提高... 详细信息

目的探讨膳食与克山病发病的关系。方法回顾并分析了克山病有关文献，调查了克山病居民的膳食变化情况。结果１９５８年后，克山病病区人群出现了偏食，导致必需氨基酸摄入不足，引起了克山病发病；１９８０年后，病区居民生活水平提高，纠正了偏食，克山病发病基本被控制。结论必需氨基酸缺乏在克山病发病中起重要作用。

关键词：克山病必需氨基酸偏食白肌病信州心肌病

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