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Performances of glaucoma operations with Kahook Dual Blade or iStent combined with phacoemulsification in Japanese open angle glaucoma patients

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International Journal of Ophthalmology(English edition) 2020年第6期13卷 941-945页

作者： Kentaro Iwasaki Yoshihiro Takamura Yusuke Orii Shogo Arimura masaru Inatani Department of Ophthalmology Faculty of Medical SciencesUniversity of FukuiFukui 910-1193Japan Department of Ophthalmology Obama HospitalFukui 917-8567Japan

AIM:To compare surgical outcomes of phacoemulsification combined with glaucoma surgical techniques performed with either Kahook Dual Blade(KDB)or iStent for Japanese patients with either primary open angle glaucoma or exfoliation ***:We retrospectively evaluated the surgical outcomes of 129 eyes of 84 Japanese patients with glaucoma who underwent KDB or 44 eyes of 34 patients who underwent phacoemulsification with iStent procedures combined with cataract *** primary outcome was surgical success or failure[with surgical failure being indicated by18 mm Hg as criterion A;IOP>14 mm Hg as criterion B on two consecutive study visits;or reoperation requirement].In addition,we assessed the number of postoperative glaucoma medications and the resulting ***:The probability of success was significantly higher in the KDB group than in the iStent group for criterion A(60.2%vs 46.4%,P=0.019).In the KDB group,the mean preoperative IOP of 19.8±7.3 mm Hg decreased significantly to 13.0±3.1 mm Hg(P<0.01),and the mean number of glaucoma medications at 2.5±1.4 decreased significantly to 1.6±1.6(P<0.01)12 mo *** the iStent group,the mean preoperative IOP of 17.8±2.9 mm Hg significantly decreased to 14.3±2.3 mm Hg(P<0.01),and the mean number of glaucoma medications at 2.2±1.1 decreased significantly to 0.9±1.4(P<0.01)12 mo *** overall IOP reduction percentage was higher in the KDB group(26.2%)than in the iStent group(19.0%)12 mo postoperatively(P=0.03).Hyphema occurred significantly more frequently in the KDB group(16.3%)than in the iStent group(2.3%,P=0.017).CONCLUSION:KDB and iStent procedures combined with cataract surgery both result in significant IOP and glaucoma medication reductions after the 12-month *** patients in the KDB group have a higher success rate for the target IOP of less than 18 mm Hg and a higher complication rate than those

关键词： glaucoma surgery surgical outcome Kahook Dual Blade iStent

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SELECTIVE FORMATION OF OXYGENATED COMPOUNDS BY SILICA-SUPPORTED Ru-Co BIMETALLIC CLUSTER-DERIVED CATALYSTS IN CO HYDROGENATION

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Chinese Science Bulletin 1992年第4期37卷 347-348页

作者：肖丰收郭燮贤 ICHIKAWA masaru Department of Chemistry Jilin University Changchun 130023 PRC Dalian Institute of Chemical Physics Academia Sinica Dalian 116023 PRC Catalysis Research Center Hokkaido University Sapporo 060 Japan

It is well known that catalysts prepared from organometallic compounds exhibit high activity and selectivity for oxygenates in CO-based reactions such as CO hydrogenation and olefin hydroformylation, in contrast to the conventional metal catalysts from the usual way of the metal salts. It is also reported that bimetallic catalysts provide quite different

关键词： hydrogenation selectivity salts olefin usual alcohols silica carbonyl aldehyde molar

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Case of pseudo-Meigs' syndrome caused by gastric cancer-related metastatic ovarian tumor with prolonged survival

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World Journal of Gastrointestinal Oncology 2016年第11期8卷 801-804页

作者： masaru Okamoto Kazunori Maeda Atsushi Yanagitani Kiwamu Tanaka Department of General Internal Medicine Tottori Prefectural Central Hospital Department of Gastroenterology Tottori Prefectural Central Hospital

A 48-year-old woman presented with bilateral enlarged ovaries, ascites, bilateral pleural effusion, and advanced gastric cancer. Pleural fluid cytology did not reveal malignant cells. Oophorectomy, performed as a palliative procedure, was followed by rapid resolution of the pleural effusion and ascites. The patient was diagnosed with pseudo-Meigs’ syndrome, and underwent chemotherapy followed by partial gastrectomy. At the last follow-up, 84 mo following oophorectomy, she was alive, and free of disease recurrence, despite not receiving any further treatment. Pseudo-Meigs’ syndrome should be considered in patients with bilateral ovarian tumors, ascites and pleural effusion, and treatment such as oophorectomy may result in symptomatic improvement and better prognosis in similar patients.

关键词： Pseudo-Meigs&rsquo syndrome Ovarian tumor Gastric cancer Pleural effusion Ascites

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Decreased hemoglobin after initial treatment is associated with treatment resistance in Kawasaki disease in Kobayashi risk stratification

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World Journal of Pediatrics 2020年第6期16卷 623-628页

作者： Yukari Atsumi Hiroshi Sakakibara Yoshihiko Morikawa Koichi Miyata Hiroyuki Yamagishi Masahiro Misawa masaru Miura Department of General Pediatrics Tokyo Metropolitan Children's Medical Center.TokyoJapan Clinical Research Support Center.Tokyo Metropolitan Children's Medical Center TokyoJapan Department of Cardiology.Tokyo Metropolitan Children's Medical Center.Tokyo Japan Department of Pediatrics Keio University School of MedicineTokyo.Japan Department of Pediatrics Tokyo Metropolitan Bokutoh HospitalTokyoJapan National Center for Global Health and Medicine.1-21-1.Toyama Shinjuku-kuTokyo 162-8655.Japan

Background Although Kawasaki disease(KD)is known to cause anemia,the relationship between its prognosis and hemoglobin level is less well *** We herein performed a secondary analysis of data from a previous study(Post-RAISE).Children aged 6 months to 2 years at the time of KD diagnosis were *** hemoglobin was defined as a decrease>10%on post-treatment day 2 compared with the level prior to the initial *** Of 1253 KD cases,treatment resistance was observed in 209(17%)and was significantly more frequent in the decreased hemoglobin group(37/167 vs.172/1086,P=0.041).Multivariable logistic regression analysis revealed that decreased hemoglobin was associated with resistance to the initial treatment(odds ratio 1.53;95%confidence interval 1.00-2.33;P=0.048).Conclusions Decreased hemoglobin was significantly associated with resistance to initial treatment in patients with KD.

关键词： Anemia Inflammation Hepcidin Kawasaki disease

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Is ERCP really necessary in case of suspected spontaneous passage of bile duct stones?

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World Journal of Gastroenterology 2009年第26期15卷 3283-3287页

作者： Yuji Sakai Toshio Tsuyuguchi Takeshi Ishihara Seigo Yukisawa Tadashi Ohara masaru Tsuboi Yoshihiko Ooka Kazuki Kato Kiyotake Katsuura Michio Kimura Makoto Takahashi Kazuhisa Nemoto masaru Miyazaki Osamu Yokosuka Department of Medicine and Clinical Oncology Graduate School of MedicineChiba University Department of Internal Medicine Funabashi Central Hospital Department of Surgery Funabashi Central Hospital Department of Radiology Funabashi Central Hospital Department of General Surgery Graduate School of MedicineChiba University

AIM:To investigate the usefulness of magnetic resonance cholangiopancreatography (MRCP) and the need for endoscopic retrograde cholangiopancreatography (ERCP) in cases of suspected spontaneous passage of stones into the common bile ***:Thirty-six patients with gallbladder stones were clinically suspected of spontaneous passage of stones into the common bile duct because they presented with clinical symptoms such as abdominal pain and fever,and showed signs of inflammatory reaction and marked rise of hepatobiliary *** symptoms resolved and they showed normalized values of blood biochemical parameters after conservative treatment without evidence of stones in the common bile duct on *** these patients were subjected to ERCP within 3 d of MRCP to check for the presence of ***:No stones were detected by ERCP in any patient,confi rming the results of ***:When clinical symptoms improve,blood biochemical parameters have normalized,and MRCP shows there are no stones in the common bile duct,it can be considered the stone has spontaneously passed and thus ERCP is not necessary.

关键词： Magnetic resonance cholangiopancreatography Endoscopic retrograde cholangiopancreatography Spontaneous passage of bile duct stones Bile duct stones Pancreatitis

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Clinicopathological features and prognosis of surgical resected cases of biliary cancer with pancreaticobiliary maljunction

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Hepatobiliary & Pancreatic Diseases International 2020年第1期19卷 97-100页

作者： Tsukasa Takayashiki Hideyuki Yoshitomi Katsunori Furukawa Satoshi Kuboki masaru Miyazaki Masayuki Ohtsuka Department of General Surgery Graduate School of MedicineChiba University Department of Gastroenterological Surgery Mita HospitalInternational University of Health and Welfare

To the Editor:Pancreaticobiliary maljunction(PBM)is a congenital anomaly in which the pancreatic and bile ducts join anatomically outside of the duodenal wall away from the Oddi’s *** condition causes the reflux of pancreatic juice into the bile duct under high pressure,resulting in various pathologic *** features of PBM patients are common bile duct dilatation,long common channel,and high amylase levels in bile *** them,one of the most significant problems is the development of biliary cancer,including extrahepatic bile duct and gallbladder cancers[1].A nationwide survey in Japan reported biliary cancer in 21.6%of adult patients with PBM concomitant with congenital biliary dilatation,32.1%and 62.3%extrahepatic bile duct and gallbladder cancers,respectively[2].

关键词： biliary cancer congenital

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Primary localized malignant biphasic mesothelioma of the liver in a patient with asbestosis

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World Journal of Gastroenterology 2009年第5期15卷 615-621页

作者： Motoko Sasaki Ichiro Araki Toshiaki Yasui masaru Kinoshita Keita Itatsu Takayuki Nojima Yasuni Nakanuma Department of Human Pathology Kanazawa University Graduate School of Medicine Kanazawa 920-8640 Japan Department of Internal Medicine Asanogawa General Hospital Kanazawa 920-8621 Japan Department of Surgery Asanogawa General Hospital Kanazawa 920-8621 Japan Hanazono Medical Office Kanazawa 920-0293 Japan Department of Pathology Kanazawa Medical University Ishikawa 920-0293 Japan

We report a case of primary localized malignant biphasic mesothelioma of the liver in a 66-year-old man associated with asbestosis. The tumor was detected as a hepatic nodule, 4 cm in diameter, in the right lobe (S8 segment) on CT scan. Histopathological examination demonstrated an intrahepatic tumor with central necrosis consisting of a papillary epithelioid pattern on the surface of the liver, microcystic (microglandular or adenomatoid) pattern mainly in the subcapsular area and sarcomatoid pattern intermingled with microcystic pattern in the major part of the hepatic nodular tumor. Tumor cells, especially of epithelioid type, showed distinct immunoreactivity for mesothelial markers (WT-1, calretinin, D2-40, CK5/6, mesothelin, thrombomodulin) and no immunoreactivity for epithelial (adenocarcinoma) markers (CEA, CD15, BerEP4, BG8, MOC31). P53 immunoreactivity was detected focally in papillary epithelioid tumor cells and extensively in microcystic and sarcomatoid components, suggesting that the papillary epithelioid mesothelioma arose on the surface of the liver, and tumor cells showing microcystic and sarcomatoid patterns invaded and grew into the liver. To date, this is the first case of primary localized malignant biphasic mesothelioma of the liver, since all three primary hepatic mesotheliomas reported so far were epithelioid type.

关键词： Malignant mesothelioma Pulmonaryasbestosis Liver Immunohistochemistry

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Optical mesoscopic membrane sensor layouts for waterfree and blood-free toxicants

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Nano Research 2015年第10期8卷 3150-3163页

作者： Sherif A. El-Safty Mohamed Khairy Mohamed A. Shenashen Emad Elshehy Wojciech Warkocki masaru Sakai NationalInstituteforMaterialsScience(NIMS) 1-2-1SengenTsukuba-shiIbaraki305-0047Japan GraduateSchoolforScienceandEngineering WasedaUniversity3-4-1OkuboShinjuku-kuTokyo169-8555Japan CenterforResearchinIsotopesandEnvironmentalDynamics TsukubaUniversity1-1-1TennodaiTsukubaIbaraki305-8572Japan

Advances in fabrication of mesoscopic membrane sensors with unique structures and morphologies inside anodic alumina membrane （AAM） nanochannels have led to the development of various methods for detecting, visualizing, adsorbing, filtering, and recovering ultra-trace concentrations of toxic metal ions, such as Hg^2＋ and Pb^2＋, in water and blood. These often ＂one-pot＂ screening methods offer advantages over conventional methods in that they do not require sophisticated instruments or laborious sample preparation. In the present study, we fabricated two mesoscopic membrane sensors for naked-eye detection, recognition, filtration, and recovery of Hg^2＋ and Pb^2＋ in biological and environmental samples. These sensors were characterized by the dense immobilization of organic colorants on the mesopore surfaces of silica nanotubes that were constructed using the nanochannels of an AAM as a scaffold. We confirmed that the nanotubes were oriented along the long axis of the AAM nanochannels, open at both ends, and completely and uniformly filled with organic colorants; also, the dense immobilization of the organic colorants did not affect the speed of ion-to-ligand binding events. We used simple, desk-top, flow-through assays to assess the suitability of the developed membrane sensors for detection, removal, and filtration of Hg^2＋ and Pb^2＋ with respect to recyclability and continuous monitoring. Removal of the target ions from biological fluids was assessed by means of flow cytometric analysis. Our results demonstrate the potential of our membrane sensors to be used for preventing the health risks associated with exposure to toxic metal ions in the environment and blood.

关键词： health risks optical sensor mesoscopic nanotubes toxins blood

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Joint observation of the concentric gravity wave event on the Tibetan Plateau

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Earth and Planetary Physics 2022年第3期6卷 219-227页

作者： Chang Lai PengWei Li JiYao Xu Wei Yuan Jia Yue Xiao Liu Kogure masaru LiLi Qian School of Science Chongqing University of Posts and TelecommunicationsChongqing 400065China State Key Laboratory of Space Weather Center for Space Science and Applied ResearchChinese Academy of SciencesBeijing 110000China Department of Physics Catholic University of AmericaWashingtonDC 20064USA College of Mathematics and Information Science Henan Normal UniversityXinxiang 410700China Department of Earth and Planetary Science Kyushu UniversityFukuoka 8190395Japan

A concentric gravity wave event was captured by a photographer in NagarzêCounty(90.28°N,28.33°E)between 02:00 and 04:00(local time)on May 11,*** concentric gravity wave event was also observed by the Suomi National Polar-orbiting Partnership satellite and the all-sky airglow imager at Yangbajing station(90.5°E,30.1°N).The temporal and spatial information on gravity waves from the photographs provided a rare opportunity to study the propagation of gravity waves over the Tibetan *** to wind and temperature data from the MERRA-2 reanalysis(Modern-Era Retrospective analysis for Research and Applications,Version 2)and empirical models(NRLMSISE-00[Naval Research Laboratory Mass Spectrometer and Incoherent Scatter Radar Exosphere]and HWM[horizontal wind model]),we inversely derived the propagation trajectory from the observed wave pattern to the source region by using the ray-tracing *** source of the concentric gravity wave was identified as deep convection in Bangladesh(90.6°E,25.0°N).The maximum background wind speed in the propagation direction(31.05 m/s)was less than the phase speed of 53 m/s,which is consistent with the wind-filtering theory.

关键词： concentric gravity wave ray-tracing method convection source Tibetan Plateau

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Plasmodium vivax cerebral malaria complicated with venous sinus thrombosis in Colombia

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Asian Pacific Journal of Tropical Medicine 2013年第5期6卷 413-415页

作者： Miguel A Pinzon Juan C Pineda Fernando Rosso masaru Shinchi Fabio Bonilla-Abadia Department of Infectious Diseases Hospital San Vicente de PaulMedellinColombia Department of Internal Medicine Fundacion Clinica Valle del LiliICESI UniversityCaliColombia Department of Infectious Diseases Fundacion Clinica Valle del LiliCaliColombia Department of Neurology Fundacion Clinica Valle del LiliCuliColombia Department of Rheumatology Fundacion Clinica Valle del LiliICESI UniversityCaliColombia

Complicated malaria is usually due to Plasmodium ***,Plasmodium vivax is infrequently related with life-threatening *** cases have been reported of severe Plasmodium vivax infection,and most of them from Southeast Asia and *** report the first case of cerebral malaria due to Plasmodium vivax in Latin America,complicated with sagittal sinus thrombosis and confirmed by a molecular method.

关键词： Cerebral malaria Vivax malaria Plasmodium vivax Intracranial sinus thrombosis

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