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Decreased desire to have children: A qualitative study

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Asian pacific Journal of Reproduction 2025年第1期14卷 21-26页

作者： maryam Ghaderi Najafabadi Zahra Shojaei Ardekani Samira Sohbati Firoozeh Mirzaee Masoumeh Ghazanfarpour Sahebeh Dadshahi Student Research Committee Kerman University of Medical SciencesKermanIran Islamic Azad University of Arsanjan FarsIran Department of Obstetrics and Gynecology Clinical Research Development UnitAfzalipour HospitalKerman University of Medical SciencesKermanIran Reproductive and Family Health Research Center Kerman University of Medical SciencesKermanIran Nursing Research Center Faculty of Nursing and MidwiferyKerman University of Medical SciencesKermanIran

Objective:To explain barriers to childbearing among working women from the perspective of working women and ***:In this study,a qualitative study of content analysis method was *** study was conducted from December 2021 to July *** population consisted of working women and *** collection was conducted using semi-structured interviews and continued until data saturation was *** purposeful sampling,10 women and 11 midwives were selected as the *** data were analyzed by Graneheim and Lundman content analysis *** more rigorous,Nvivo 14 software was also used for data management,analysis,coding and organization of ***:This study included 21 women(10 women employees and 11 midwives)aged 25-43 years(for women employees)and 27-56 years(for midwives)with 1 to 34 years of job *** examination of participant’views about the barriers to childbearing,1124 codes were identified,of which we managed to extract six subthemes and two *** themes emerged:“lack of social support and lack of family support”.Subthemes of“lack of social support”were“inadequate leave,long distance from workplace,and insufficient wages”.Subthemes of“lack of family support”were“lack of spouse support,lack of spouse's family support,and lack of their family support”.Conclusions:Different socioeconomic factors influence childbearing tendency in working *** and family supports play an important role in this *** is important to take these factors into account at the time of policymaking in the field of midwifery.

关键词： Content analysis Employee women Childbearing Midwives Qualitative study

Promising effects of Persian shallot extract on the serum markers and blood pressure of patients with metabolic syndrome:a double-blinded randomized controlled trial

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Journal of Traditional Chinese Medicine 2025年第1期45卷 100-106页

作者： Neda Naimipoor Zahra Bagheri-Hosseinabadi Mohammad Reza Hajizadeh Mitra Abbasifard Mohammad Reza Mirzaei Akram Ghadiri Anari maryam Mohammad-Sadeghipour Mehdi Mahmoodi Department of Clinical Biochemistry School of MedicineRafsanjan University of Medical Sciences Department of Internal Medicine School of MedicineAli-Ibn Abi-Talib HospitalRafsanjan University of Medical Sciences Molecular Medicine Research Center Research Institute of Basic Medical SciencesRafsanjan University of Medical Sciences Diabetes Research Center Shahid Sadoughi University of Medical Sciences Department of Clinical Biochemistry Afzalipour School of MedicineKerman University of Medical Sciences Physiology Research Center Institute of NeuropharmacologyKerman University of Medical Sciences

OBJECTIVE: To evaluate the effect of Persian shallot extract on the serum markers and blood pressure of patients with metabolic syndrome(MetS). METHODS: Fifty patients with Met S diagnosis were randomly assigned to the intervention(Persian shallot extract) and the control(placebo) group. Both groups received treatment for three months. Before the study and at the end of the study, 5 mL peripheral blood was taken from each patient. The measured factors included total antioxidant capacity(TAC), superoxide dismutase enzyme(SOD), malondialdehyde, oxidized low-density lipoprotein(Ox-LDL), apolipoprotein H(Apo-H), fasting blood glucose(FBS), total cholesterol, triglycerides, high-density lipoprotein(HDL), LDL, and systolic and diastolic blood pressure. RESULTS: At baseline, the evaluated parameters were not significantly different between the intervention and control groups. At the end of the study, the mean serum levels of malondialdehyde and ox-LDL were significantly lower in the intervention group. The mean FBS, cholesterol, triglycerides, and LDL were significantly lower in the intervention group. The mean TAC and HDL were significantly higher in the intervention group(P < 0.05). Moreover, the intervention group significantly reduced systolic and diastolic blood pressure. No other significant association was observed. CONCLUSION: Persian shallot extract has several beneficial effects in Met S patients, including optimizing oxidative balance, reducing blood pressure, fasting blood sugar, and blood lipid profile.

关键词： antioxidants medicine, Persian metabolic syndrome shallots

Improving dexamethasone drug loading and efficacy in treating rheumatoid arthritis via liposome:Focusing on inflammation and molecular mechanisms

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Animal Models and Experimental Medicine 2025年第1期8卷 5-19页

作者： Mohammad Yasin Zamanian Hamidreza Zafari Maria K.Osminina Alla A.Skakodub Raed Fanoukh Aboqader Al-Aouadi maryam Golmohammadi Nikta Nikbakht Iman Fatemi Department of Physiology School of MedicineHamadan University of Medical SciencesHamadanIran Department of Pharmacology and Toxicology School of PharmacyHamadan University of Medical SciencesHamadanIran Department of Orthopedic Surgery Joint Reconstruction Research CenterImam Khomeini Hospital ComplexSchool of MedicineTehran University of Medical SciencesTehranIran Pediatric department I.M.Sechenov First Moscow State Medical University of the Ministry of Health of Russia(Sechenov University)MoscowRussian Federation Department of Pediatric Preventive Dentistry E.V.Borovsky I.M.Sechenov First Moscow State Medical University of the Ministry of Health of Russia(Sechenov University)MoscowRussian Federation Department of Medicine College of MedicineAl-Ayen Iraqi UniversityThi-QarIraq School of Medicine Shahid Beheshti University of Medical SciencesTehranIran Department of Physical Medicine and Rehabilitation School of PharmacyHamadan University of Medical SciencesHamadanIran Research Center of Tropical and Infectious Diseases Kerman University of Medical SciencesKermanIran

Rheumatoid arthritis(RA)is a chronic autoimmune disease that affects approxi-mately 0.46%of the global *** therapeutics for RA,including disease-modifying antirheumatic drugs(DMARDs),nonsteroidal anti-inflammatory drugs(NSAIDs),and corticosteroids,frequently result in unintended adverse ***(DEX)is a potent glucocorticoid used to treat RA due to its anti-inflammatory and immunosuppressive *** delivery of DEX,particu-larly when liposomes are surface-modified with targeting ligands like peptides or sialic acid,can improve drug efficacy by enhancing its distribution to inflamed joints and minimizing *** study investigates the potential of liposomal drug delivery systems to enhance the efficacy and targeting of DEX in the treatment of *** from various studies demonstrate that liposomal DEX significantly inhibits arthritis progression in animal models,reduces joint inflammation and damage,and alleviates cartilage destruction compared to free *** liposomal formulation also shows better hemocompatibility,fewer adverse effects on body weight and immune organ index,and a longer circulation time with higher *** anti-inflammatory mechanism is associated with the downregulation of pro-inflammatory cytokines like tumor necrosis factor-α(TNF-α)and B-cell-activating factor(BAFF),which are key players in the pathogenesis of ***,liposomal DEX can induce the expres-sion of anti-inflammatory cytokines like interleukin-10(IL-10),which has significant anti-inflammatory and immunoregulatory *** findings suggest that lipo-somal DEX represents a promising candidate for effective and safe RA therapy,with the potential to improve the management of this debilitating disease by providing targeted delivery and sustained release of the drug.

关键词： dexamethasone inflammation liposome rheumatoid arthritis TNF-α

Current role of extracorporeal membrane oxygenation for the management of trauma patients:Indications and results

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World Journal of Critical Care Medicine 2025年第1期14卷 42-48页

作者： Mohammed Abdulrahman maryam Makki Malak Bentaleb Dana Khamis Altamimi Marcelo AF Ribeiro Junior Department of Surgery College of Medicine and Health SciencesKhalifa UniversityAbu Dhabi 11001United Arab Emirates Department of Surgery Division of TraumaCritical Care and Acute Care SurgerySheikh Shakhbout Medical CityAbu Dhabi 11001United Arab Emirates Department of Surgery Sheikh Shakhbout Medical CityAbu Dhabi 91888ADUnited Arab Emirates Department of Surgery R Adams Cowley Shock Trauma CenterUniversity of MarylandBaltimoreMD 21201United States

Extracorporeal membrane oxygenation(ECMO)has emerged as a vital circulatory life support measure for patients with critical cardiac or pulmonary conditions unresponsive to conventional *** allows blood to be extracted from a patient and introduced to a machine that oxygenates blood and removes carbon *** blood is then reintroduced into the patient’s circulatory *** process makes ECMO essential for treating various medical conditions,both as a standalone therapy and as adjuvant ***-venous(VV)ECMO primarily supports respiratory function and indicates respiratory ***,veno-arterial(VA)ECMO provides hemodynamic and respiratory support and is suitable for cardiac-related *** study reviews recent literature to elucidate the evolving role of ECMO in trauma care,considering its procedural intricacies,indications,contraindications,and associated ***,the use of ECMO in trauma patients,particularly for acute respiratory distress syndrome and cardiogenic shock,has demonstrated promising outcomes despite challenges such as anticoagulation management and complications such as acute kidney injury,bleeding,thrombosis,and *** studies have shown that VV ECMO was associated with significantly higher survival rates than conventional mechanical ventilation,whereas other studies have reported that VA ECMO was associated with lower survival rates than VV *** plays a critical role in managing trauma patients,particularly those with acute respiratory *** research is necessary to explore the full potential of ECMO in trauma *** should have a clear understanding of the indications and contraindications for the use of ECMO to maximize its benefits in treating trauma patients.

关键词： Extracorporeal membrane oxygenation treatments Multiple trauma Respiratory distress syndrome Cardiogenic shock Contraindications Anticoagulants

Rosa moschata ameliorates haloperidol-induced Parkinson's disease via reduction of neurodegeneration and oxidative stress

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Asian Pacific Journal of Tropical Biomedicine 2025年第1期15卷 24-33,I0013-I0015页

作者： Badriyah S.Alotaibi Uzma Saleem maryam Farrukh Zunera Chaudhary Nabia Anwar Ifat Alsharif Abdullah R.Alanzi Tasahil S.Albishi Fatima A.Jaber Wedad Saeed Al-Qahtani Muhammad Ajmal Shah Department of Pharmaceutical Sciences College of PharmacyPrincess Nourah bint Abdulrahman UniversityP.O.Box 84428Riyadh 11671Saudi Arabia Punjab University College of Pharmacy University of the PunjabLahore-54000Pakistan Department of Pharmacology Faculty of Pharmaceutical SciencesGovt.College UniversityFaisalabad-38000Pakistan Department of Biology Jamoum University CollegeUmm Al-Qura University-21955 MakkahSaudi Arabia Department of Pharmacognosy College of PharmacyKing Saud UniversityRiyadh-11451Saudi Arabia Department of Biology College of SciencesUmm Al-Qura UniversityMakkahSaudi Arabia Department of Biological Sciences College of ScienceUniversity of JeddahJeddah 21589Saudi Arabia Department of Forensic Sciences College of Criminal JusticeNaif Arab University for Security SciencesP.O.Box 6830Riyadh 11452Saudi Arabia Department of Pharmacy Hazara UniversityMansehra-21300Pakistan

Objective:To investigate the effect of Rosa moschata(***)extract on haloperidol-induced Parkinson’s disease(PD)in ***:Haloperidol(1 mg/kg)was given to rats intraperitoneally for 3 weeks for induction of *** extract(150,300 and 600 mg/kg)was administered orally for 21 *** neuroprotective role of *** leaf extract in PD was explored by performing neurobehavioral tests and RT-PCR analysis and measuring neurotransmitters and oxidative stress ***:An improvement in motor functions and muscle strength was observed in PD rats treated with *** *** levels of dopamine,serotonin,noradrenaline,superoxide dismutase,catalase,glutathione,and superoxide dismutase were significantly increased(P<0.001),whereas acetylcholinesterase and malondialdehyde levels were markedly decreased by treatment with *** extract(P<0.001).The extract also markedly downregulated the mRNA expressions of IL-1β,α-synuclein,IL-1α,and TNF-αin brain ***,histopathological analysis indicated that neurofibrillary tangles and plaques were noticeably decreased in a dose-dependent manner in PD rats treated with *** ***:*** extract alleviates haloperidol-induced PD in rats by reducing oxidative stress and *** may be used for management and treatment of *** additional studies are required to confirm its efficacy and molecular mechanisms.

关键词： Parkinson’s disease Rosa moschata Neurotransmitter,α-Synuclein Haloperidol Neurodegeneration

Structural transition of NRC4 to hexameric resistosome activates plant immunity

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Molecular Plant 2025年第1期18卷 25-25页

作者： M.Arif Ashraf maryam Rashidzade Department of Biology Howard UniversityWashingtonDCUSA Department of Biology University of Massachusetts AmherstAmherstMAUSA

Plant innate immunity is governed by complex molecular mechanisms,with nucleotide-binding leucine-rich repeat receptors(NLRs)playing a central role in defense against microbial *** are generally classified into two main types:“sensor”NLRs(sNLRs),which detect pathogen molecules,and“helper”NLRs(hNLRs),which support the activation of immune *** function alongside sNLRs to modulate immune defenses,often by forming larger protein complexes known as resistosomes,which play a role in the initiation of effector-triggered immunity(Jones et al.,2024).

关键词： complexes governed transition

Carotenoids as a nutraceutical and health-promoting dietary supplement for human and animals:an updated review

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Traditional Medicine Research 2025年第3期10卷 8-20页

作者： Mahrukh Babar Jameel Ahmed Buzdar Azka Zaheer Nizam-ud-din Ghulam Mustafa Bilal Ahmed Khan maryam Hanif Tayyaba Asghar Abdul Qadeer Institute of Physiology and Pharmacology University of Agriculture FaisalabadFaisalabad 38000Pakistan Department of Pharmacy Abasyn UniversityIslamabad 46000Pakistan Livestock and Dairy Development Department Government of BalochistanQuetta 87650Pakistan Department of Epidemiology and Public Health University of Agriculture FaisalabadFaisalabad 38000Pakistan Department of Pharmacology and Toxicology University of Veterinary and Animal SciencesLahore 54000Pakistan Department of Cell Biology School of Life SciencesCentral South UniversityChangsha 410013China

Carotenoids are naturally occurring pigments found in various fruits,vegetables,algae,insects,fungi,*** nutritional supplements,carotenoids have gained considerable attention for their potential therapeutic and health-promoting effects,making them significant components of alternative and traditional medicine *** have many health benefits,particularly disease *** such as lutein,lycopene,and beta-carotene possess strong antioxidant properties,which help mitigate oxidative stress and reduce the risk of chronic diseases,including cancer,cardiovascular diseases,and eye *** play a vital role in various health conditions,including coronavirus disease-19(COVID-19),vision disorders,Alzheimer’s disease,reproductive health,cosmetic applications,diabetes management,infant formula,and animal *** alternative medicine,carotenoids are valued for enhancing immune function,reducing oxidative damage,and lowering the risk of chronic *** benefits extend to improving cognitive function and potentially delaying the progression of Alzheimer’s disease,protecting against age-related macular degeneration and other vision problems,and supporting COVID-19 *** skin care,carotenoids contribute to skin health and beauty,while in diabetes management,they aid in blood glucose *** review especially emphasizes the potential of carotenoids as vital components in health management strategies within alternative medicine and underscores the need for further research to optimize their use in nutraceutical applications.

关键词： carotenoids therapeutic effect COVID Alzheimer’s oxidative stress

Anharmonic 1D actuator model including electrostatic and Casimir forces with fractional damping perturbed by an external force

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Acta Mechanica Sinica 2018年第3期34卷 528-541页

作者： maryam Mansoori Kermani maryam Dehestani Department of Chemistry Shahid Bahonar University of Kerman

We modeled a one-dimensional actuator including the Casimir and electrostatic forces perturbed by an external force with fractional damping. The movable electrode was assumed to oscillate by an anharmonic elastic force originated from Murrell- Mottram or Lippincott potential. The nonlinear equations have been solved via the Adomian decomposition method. The behavior of the displacement of the electrode from equilibrium position, its velocity and acceleration were described versus time. Also, the changes of the displacement have been investigated according to the frequency of the external force and the voltage of the electrostatic force. The convergence of the Adomian method and the effect of the orders of expansion on the displacement versus time, frequency, and voltage were discussed. The pull-in parameter was obtained and compared with the other models in the literature. This parameter was described versus the equilibrium position and anharmonicity constant.

关键词： Murrell-Mottram potential Lippincott potential Casimir force Fractional damping Pull-in parameter Adomian decomposition method

On Countably Generated Dimension

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Algebra Colloquium 2021年第3期28卷 361-366页

作者： maryam Davoudian Department of Mathematics Shahid Chamran University of AhvazAhvazIran

In this article,we introduce and study the concept of countably generated dimension,which is a Krull-like dimension extension of the concept of DCC on countably generated *** show that some of the basic results of Krull dimension are true for countably generated *** is shown that an jR-module M has Krull dimension if and only if it has countably generated dimension,and its Krull dimension and countably generated dimension coincide.

关键词： countably generated module Krull dimension countably generated dimension