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AITEB - An European Research Project on Aero-thermodynamics of.Turbine Endwalls and Blades

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Journal of.Thermal Science 2004年第2期13卷 97-108页

作者： f. HASELBACH H.-P. SCHIf.ER Rolls-Royce Deutschland Turbines Eschenweg 11 15827 Dahlewitz GermanyRolls-Royce Deutschland Turbines Eschenweg 11 15827 Dahlewitz Germany

The paper delivers an overview on the European research project AITEB - Aerothermal Investigations on Turbine Endwalls and Blades, which started in year 2000 in the course of.the 5. f.amework Programme (GROWTH). The aim is to submit an integrated technology and design tool package f.r the advanced, aerothermal highly loaded design of.turbines, especially: Experimental/numerical investigation on heat transf.r and f.lm-cooling in separated f.ow f.r highly loaded blades including advanced trailing edge cooling Heat transf.r/ improved cooling of.turbine endwalls: Experimental/numerical work on cooling of.turbine endwalls, shrouds and recessed blade tips. Optimised Cf.-process (drawing-grid-modelling-postprocessing-risk assessment) in order to derive the 'best practice' to use Cf. as a time ef.ective tool. Af.er most of.the project lif., an overview on the project is delivered. Experimental results of.test series at various test sites are compared to numerical simulations of.the industrial and university partners.

关键词： turbines aerothermal endwalls blades cooling-technology experiment Cf..

Inf.uence of.PtMo Structure and Composition on the Adsorption Energies, Adsorption Site and Vibrational f.equency of.Carbon Monoxide

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Chinese Journal of.Structural Chemistry 2007年第7期26卷 843-849页

作者：吉智 Abraham f. Jalbout 李俊篯 Department of.Chemistry Fuzhou University Fuzhou Institute of.Chemistry National Autonomous University of Mexico Mexico City MX

Density f.nctional theory periodic slab calculations were carded out f.r CO adsorption on a series of.Mo modif.ed Pt（111） surf.ces to provide an insight into the interaction between CO and doped metal surf.ce, an important issue in CO oxidation as well as in promotion and poisoning ef.ects of.catalysis. The modif.cation of.adsorption properties with respect to those of.adsorption on the pure Mo（110） and Pt（111） is described in terms of.changes in the adsorption energies, adsorption sites and vibrational properties occurring upon alloying. We believe that the present Df. calculations can provide important inf.rmation into optimal alloy composition f.r CO-tolerance, which is not easily obtained by experimental methods.

关键词： density f.nctional calculations adsorption molybdenum platinum carbon monoxide bimetallic surf.ces

Generation of.natural killer cells f.om hematopoietic stem cells in vitro f.r immunotherapy

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Cellular & Molecular Immunology 2012年第4期9卷 310-320页

作者： martha Luevano Alejandro Madrigal Aurore Saudemont Anthony Nolan Research Institute and University College London Royal Free Campus London UK

Natural killer （NK） cells are part of.the innate immune system and are an alluring option f.r immunotherapy due to their ability to kill inf.cted cells or cancer cells without prior sensitization. Throughout the past 20 years, dif.erent groups have been able to reproduce NK cell development in vitro, and NK cell ontogeny studies have provided the basis f.r the establishment of.protocols to produce NK cells in vitro f.r immunotherapy. Here, we brief.y discuss NK cell development and NK cell immunotherapy approaches. We review the f.ctors needed f.r NK cell dif.erentiation in vitro, which stem cell sources have been used, published protocols, challenges and f.ture directions f.r Good Manuf.cturing Practice protocols.

关键词： cord blood natural killer cells dif.erentiation

Dimerization energetics of.curli f.ber subunits CsgA and CsgB

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npj Computational Materials 2019年第1期5卷 923-931页

作者： martha Dunbar Elizabeth DeBenedictis Sinan Keten Department of.Mechanical Engineering Northwestern UniversityEvanstonIL 60208USA Department of.Civil and Environmental Engineering Northwestern UniversityEvanstonIL 60208USA

Curli f.bers are f.nctional amyloids that exhibit strong adhesion and robust self.assembly as biof.lm structural components;however,the binding energetics and mechanical properties of.wild-type curli are not well *** address this,we present dimer structures made up of.the major and minor curli subunits(CsgA and CsgB),perf.rm f.ee energy calculations to obtain absolute binding energies,and estimate the Young’s modulus and persistence length of.curli *** molecular dynamics simulations are used to evaluate nonbonded *** energies are most f.vorable f.r CsgB–CsgA,while CsgA–CsgA dimers have a higher binding energy than CsgB–CsgB despite possessing less f.vorable nonbonded interaction *** each potential of.mean f.rce of.separation indicated that solvent ef.ects positively impact CsgA–CsgA binding but not CsgB–CsgB and CsgB–*** residues and conserved polar residues were also notable contributors to attractive nonbonded interactions,underlining their importance in dimer *** f.ndings elucidate sequence ef.ects on binding energy contributions and establish theoretical limits f.r the elasticity,persistence length,and strength of.curli f.bers.

关键词： bonded residues elasticity

Putative nicotinic acetylcholine receptor subunits express dif.erentially through the lif. cycle of.codling moth, Cydia pomonella （Lepidoptera： Tortricidae）

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Insect Science 2016年第2期23卷 277-287页

作者： Jessica A. Martin Stephen f. Garczynski USDA-ARS Yakima Agricultural Research Laboratory Wapato WA 98951 USA

Nicotinic acetylcholine receptors （nAChRs） are the targets of.neonicotinoids and spinosads, two insecticides used in orchards to ef.ectively control codling moth, Cydia pomonella （L.）（Lepidoptera： Tortricidae）. Orchardists in Washington State are concerned about the possibility of.codling moth f.eld populations developing resistance to these two insecticides. In an ef.ort to help mitigate this issue, we initiated a project to identif. and characterize codling moth nAChR subunits expressed in heads. This study had two main goals; （i） identif. transcripts f.om a codling moth head transcriptome that encode f.r nAChR subunits, and （ii） determine nAChR subunit expression prof.les in various lif. stages of.codling moth. f.om a codling moth head transcriptome, 24 transcripts encoding f.r 12 putative nAChR subunit classes were identif.ed and verif.ed by PCR amplif.cation, cloning, and sequence determination. Characterization of.the deduced protein sequences encoded by putative nAChR transcripts revealed that they share the distinguishing f.atures of.the cys-loop ligand-gated ion channel superf.mily with 9 α-type subunits and 3 β- type subunits identif.ed. Phylogenetic analysis comparing these protein sequences to those of.other insect nAChR subunits supports the identif.cation of.these proteins as nAChR subunits. Stage expression studies determined that there is clear dif.erential expression of.many of.these subunits throughout the codling moth lif. cycle. The inf.rmation f.om this study will be used in the f.ture to monitor f.r potential target-site resistance mechanisms to neonicotinoids and spinosads in tolerant codling moth populations.

关键词： codling moth nAChR expression nicotinic acetylcholine receptor subunits

ON MULTIPLICATION AND COMULTIPLICATION MODULES

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Acta Mathematica Scientia 2011年第2期31卷 694-700页

作者： H. Ansari-Toroghy f. f.rshadif.r Department of.Mathematics Faculty of Science University of Guilan

This article deals with some results concerning multiplication and comultipli- cation modules over a commutative ring.

关键词： Multiplication modules comultiplication modules cocyclic modules

The Quotient Category of.a Graded Morita-Takeuchi Context

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Acta Mathematica Sinica,English Series 2006年第1期22卷 123-130页

作者： f. CASTANO IGLESIAS C. NASTASESCU Departamento de Estadistica y Matemdtica Aplicada Universidad de Almeria 04120 Almeria Spain f.cultatea de Matematica Str. Academiei 14 RO-70109 Bucharest Romania

In this paper, we of.er a graded equivalence between the quotient categories def.ned by any graded Morita-Takeuchi context via certain modif.cations of.the graded cotensor f.nctors. As a consequence, we show a commutative diagram that establish the relation between the closed objects of.the categories gr^c and M^C, where C is a graded coalgebra.

关键词： Graded coalgebra Graded Morita context Quotient category

The Zariski Topology on the Second Spectrum of.a Module

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Algebra Colloquium 2014年第4期21卷 671-688页

作者： H. Ansari-Toroghy f. f.rshadif.r Department of.Pure Mathematics Faculty of Mathematical Sciences University of Guilan P.O. Box 41335-19141 Rasht Iran

Let R be a commutative ring and M be an R-module. The second spectrum Spec^S（M） of.M is the collection of.all second submodules of.M. We topologize Spec^S（M） with Zariski topology, which is analogous to that f.r Spec（R）, and investigate this topolog- ical space. f.r various types of.modules M, we obtain conditions under which Spec^S（M） is a spectral space. We also investigate Specs （M） with quasi-Zariski topology.

关键词： second submodule second spectrum cotop module spectral space Zariskitopology

An evolutionary perspective on conf.ict and compensation in physiological and f.nctional traits

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Current Zoology 2014年第6期60卷 755-767页

作者： Jerry f. HUSAK Simon R LAILVAUX Department of.Biology University of St. Thomas 2115 Summit Avenue St Paul MN 55105 USA Department of.Biological Sciences University of New Orleans 2000 Lakeshore Drive New Orleans LA 70148 USA

Physiological and f.nctional traits, especially those related to behavior and whole-organism perf.rmance capacities, are subject to a variety of.both parallel and opposing natural and sexual selection pressures. These selection pressures show considerable interspecif.c variation, shaping contemporary behavioral and f.nctional diversity, but the f.rm and intensity of.selection on physiological and f.nctional traits can also vary intraspecif.cally. The same suites of.traits can experience quite dif.erent se- lection pressures, depending on the sex or age of.a given individual, as well as the presence and nature of.alternative reproductive strategies and tactics. These inter- and intra-locus genetic conf.icts have potentially important consequences f.r the evolutionary trajectories of.traits subject to them. Consequently, any intraspecif.c conf.icts which could displace traits f.om their selective op- tima in certain classes of.individuals relative to others are expected to result in selection f.r mechanisms to compensate f.r devia- tion f.om those optima. Such conf.icts include interlocus sexual conf.ict, intralocus sexual conf.ict, and interacting phenotypes, as well as conf.ict within a sex. In this paper, we consider the evidence f.r, and implications of. such conf.icts f.r physiological and f.nctional traits in diverse taxa, including both vertebrates and invertebrates, and evaluate the various mechanisms, ranging f.om behavioral and mechanical to energetic and genetic, enabling compensation. We also discuss how pre- and post-mating conf.icts, as well as interacting phenotypes, might af.ect the evolution of.behavior and physiological and f.nctional traits. Investigators that seek to understand the links among behavior, morphology, physiology, and f.nction should consider such conf.icts.

关键词： Sexual Conf.ict Compensation Sexual Selection Whole-organism Perf.rmance