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现代显示 2000年第2期 25-30页

作者： mark t.johnson Aad Sempel 菲利浦研究实验室荷兰艾恩德霍芬

介绍聚合物发光二极管(poly_LED)矩阵显示器的发展历史、结构、原理及降低功耗的方法。最后介绍有源矩阵 poly_LED显示器的制作工艺和驱动方法。

关键词：聚合物发光二极管有源矩阵显示器

Is Deep time Geology Scientific?

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Journal of Earth Science 2024年第2期35卷 700-703页

作者： t.mark Harrison Department of Earth Planetary and Space SciencesUniversity of CaliforniaLos Angeles90095USA

We all know what car mechanics *** maintain and repair our automobiles according to established engineering *** all know what physicians *** maintain and repair our bodies according to established medical *** what is it that I do as a scientist?Indeed,am I a scientist?the answer to these questions depends on what we meant by“science”.

关键词： maintain Deep repair

Antimicrobial stewardship and targeted therapies in the changing landscape of maternal sepsis

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Journal of Intensive Medicine 2024年第1期4卷 46-61页

作者： Nishel M Shah Esmita Charani Damien Ming Fook-Choe Cheah mark R johnson Department of Metabolism Digestion and ReproductionImperial College LondonChelsea and Westminster HospitalLondonUK Health Protection Research Unit in Healthcare Associated Infection and Antimicrobial Resistance Imperial College LondonLondonUK Division of Infectious Diseases and HIV Medicine Department of MedicineGroote Schuur HospitalUniversity of Cape TownCape TownSouth Africa Department of Infectious Diseases Imperial College LondonChelsea and Westminster HospitalLondonUK Department of Paediatrics Faculty of MedicineUniversiti Kebangsaan Malaysia Medical CentreKuala LumpurMalaysia

Pregnant and postnatal women are a high-risk population particularly prone to rapid progression to sepsis with significant morbidity and mortality ***,severe maternal infections can have a serious detrimental impact on neonates with almost 1 million neonatal deaths annually attributed to maternal infection or *** this review we discuss the susceptibility of pregnant women and their specific physiological and immunological adaptations that contribute to their vulnerability to sepsis,the implications for the neonate,as well as the issues with antimicrobial stewardship and the challenges this poses when attempting to reach a balance between clinical care and urgent ***,we review advancements in the development of pregnancy-specific diagnostic and therapeutic approaches and how these can be used to optimize the care of pregnant women and neonates.

关键词： Sepsis Pregnancy Immunology Cardiovascular Personalised medicine Antibiotic stewardship

SARS-CoV-2 and innate immunity:the good,the bad,and the"goldilocks"

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Cellular & Molecular Immunology 2024年第2期21卷 171-183页

作者： Benjamin L.Sievers mark t.K.Cheng Kata Csiba Bo Meng Ravindra K.Gupta Department of Medicine University of CambridgeCambridgeUK Cambridge Institute of therapeutic Immunology&Infectious Disease(CItID) Department of MedicineUniversity of CambridgeCambridgeUk

An ancient conflict between hosts and pathogens has driven the innate and adaptive arms of *** about this interplay can not only help us identify biological mechanisms but also reveal pathogen vulnerabilities that can be leveraged *** humoral response to SARS-CoV-2 infection has been the focus of intense research,and the role of the innate immune system has received significantly less ***,we review current knowledge of the innate immune response to SARS-CoV-2 infection and the various means SARS-CoV-2 employs to evade innate defense *** also consider the role of innate immunity in SARS-CoV-2 vaccines and in the phenomenon of long COVID.

关键词： SARS-CoV-2 Innate immune response Interferon Cytokines Inflammation Antiviral targets

the Wave Front Set Correspondence for Dual Pairs with One Member Compact

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Acta Mathematica Sinica,English Series 2024年第3期40卷 823-869页

作者： mark MCKEE Angela PASQUALE tomasz PRZEBINDA Hammond Lane ProvidenceUT 84332USA Universite de Lorraine CNRSIECLF-57000 MetzFrance Department of Mathematics University of OklahomaNormanOK 73019USA

Let W be a real symplectic space and(G,G')an irreducible dual pair in Sp(W),in the sense of Howe,with G *** G be the preimage of G in the metaplectic group Sp(W).Given an irreducible unitary representation II of G that occurs in the restriction of the Weil representation to G,let On denote its *** prove that,for a suitable embedding t of Sp(W)in the space of tempered distributions on W,the distribution t(On)admits an asymptotic limit,and the limit is a nilpotent orbital *** an application,we compute the wave front set of II',the representation of G dual to II,by elementary means.

关键词： Reductive dual pairs Howe duality Weil representation wave front set orbital integrals

Analysis of the inflection points of height-diameter models

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Forest Ecosystems 2024年第4期11卷 414-422页

作者： tzeng Yih Lam mark J.Ducey Department of Forest Resources Management Faculty of ForestryThe University of British Columbia2045-2424 Main MallVancouverBCV6T 1Z4 Canada Department of Natural Resources and the Environment University of New Hampshire114 James HallDurhamNH 03824USA

the inflection point is an important feature of sigmoidal height-diameter(H-D)*** is often cited as one of the properties favoring sigmoidal model ***,there are very few studies analyzing the inflection points of H-D *** goals of this study were to theoretically and empirically examine the behaviors of inflection points of six common H-D models with a regional *** six models were the Wykoff(WYK),Schumacher(SCH),Curtis(CUR),HossfeldⅣ(HOS),von Bertalanffy-Richards(VBR),and Gompertz(GPZ)*** models were first fitted in their base forms with tree species as random effects and were then expanded to include functional traits and spatial *** distributions of the estimated inflection points were similar between the two-parameter models WYK,SCH,and CUR,but were different between the threeparameter models HOS,VBR,and *** produced some of the largest inflection *** and VBR produced concave H-D curves without inflection points for 12.7%and 39.7%of the tree *** species or decreasing shade tolerance resulted in larger inflection *** trends in the estimated inflection points of HOS and VBR were entirely opposite across the ***,HOS could produce concave H-D curves for portions of the *** on the studied behaviors,the choice between two-parameter models may not *** recommend comparing seve ral three-parameter model forms for consistency in estimated inflection points before deciding on *** sigmoidal models to have inflection points does not necessarily mean that they will produce fitted curves with *** study highlights the need to integrate analysis of inflection points into modeling H-D relationships.

关键词： Concavity Forest inventory and analysis Generalized height-diameter models Growth functions Height-diameter functions Mixed-effects modeling Points of inflection Species-specific models

Monomeric C-reactive protein:a link between chronic inflammation and neurodegeneration?

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Neural Regeneration Research 2024年第8期19卷 1643-1644页

作者： Nicoleta Arnaut Ylenia Pastorello mark Slevin George Emil Palade University of Medicine PharmacyScience and TechnologyTârgu MuresRomania Department of Anatomy and Embryology George Emil Palade University of MedicinePharmacyScience and TechnologyTârgu MuresRomania Center for Advanced Medical and Pharmaceutical Research(CCAMF) George Emil Palade University of MedicinePharmacyScience and TechnologyTârgu MuresRomania

Pre-diabetic insulin resistance is associated with sub-clinical inflammation and concomitant increase in systemic C-reactive protein(CRP)*** 2 diabetes mellitus(t2DM)patients register even higher chronic levels of inflammation,with excess circulating CRP originating from both typical hepatic synthesis,and also visceral white adipose tissue.

关键词： inflammation reactive clinical

p38-MAPK and CDK5,signaling pathways in neuroinflammation:a potential therapeutic intervention in Alzheimer's disease?

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Neural Regeneration Research 2024年第8期19卷 1649-1650页

作者： Vlad Ionut Viorel Ylenia Pastorello Nosherwan Bajwa mark Slevin George Emil Palade University of Medicine PharmacyScience and TechnologyTârgu MuresRomania Department of Anatomy and Embryology George Emil Palade University of MedicinePharmacyScience and TechnologyTargu MuresRomania DIAKO Hospital FlensburgGermany Center for Advanced Medical and Pharmaceutical Research(CCAMF) George Emil Palade University of MedicinePharmacyScience and TechnologyTârgu MuresRomania Manchester Metropolitan University ManchesterUK

Alzheimer’s disease(AD),the most common type of dementia,affects millions of people worldwide,putting a significant strain on healthcare infrastructure and societal *** is characte rized by the build-up of amyloid-be... 详细信息

关键词： Alzheimer Aβ tau

Regioselective cation exchange reaction for photoelectrochemical water splitting

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Rare Metals 2024年第7期43卷 3400-3407页

作者： Mo-Yan Chen tai-Song Zhang Zhi Yan Jiang-Nan Lv Xiao-ting Sun Rui-Xia Yang mark tSwihart Xiao-Hong Xu Yang Liu Research Institute of Materials Science of Shanxi Normal University&Key Laboratory of Magnetic Molecules and Magnetic Information Materials of Ministry of Education Taiyuan 030031China Department of Chemical and Biological Engineering University at Buffalo(SUNY)NY 14260USA Department of Materials Science Fudan UniversityShanghai 200433China

Engineering copper sulfide-based heterostructures via cation exchange(CE)is an appealing approach,as it allows selective combination of distinct compositions and functions of metal *** heterostructures can play a significant role in photoelectrochemical applications,but the effect of the ratio between two or more domains in such heterostructures on the photoresponse has not been well explored.

关键词： exchange sulfide splitting

Does a large prostate size, small lesion volume, or long needle distance from the probe to the lesion reduce magnetic resonance imaging-targeted cancer detection?

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CURRENt UROLOGY 2024年第2期18卷 144-147页

作者： Bevill, mark D. Drobish, Justin N. Flynn, Kevin J. Rajput, Maheen Metz, Catherine tracy, Chad R. Gellhaus, Paul t. Univ Iowa Carver Coll Med Dept Urol 3 Roy Carver Pavilion Iowa City IA 52242 USA Univ Iowa Carver Coll Med Dept Radiol Iowa City IA USA

BackgroundWe aimed to evaluate whether large prostate size, small lesion volume, or long lesion distance from the ultrasound probe tip would decrease cancer detection in transrectal magnetic resonance imaging (MRI)-targeted *** and methodsPatients who underwent MRI-targeted biopsy at our institution between May 2017 and August 2019 were enrolled in a prospective database. three to 5 cores were obtained from >= 2 prostate imaging reporting and data system v2 lesions. A multivariable model was created that included needle distance to the lesion, prostate specific antigen, prostate imaging reporting and data system, lesion volume, and prostate *** total of 377 patients with 533 lesions underwent a biopsy during the study period. A total of 233 (44%) lesions were positive for prostate cancer, and 173 (32%) lesions had clinically significant prostate cancer. the mean needle distance to the lesion was 11.7 mm (interquartile range, 7.6-15.5 mm). the likelihood of obtaining a positive core on biopsy decreased as the distance from the ultrasound probe increased for all prostate cancers and clinically significant prostate cancer (p = 0.018 and p = 0.004, respectively). Every 10 mm from the rectum, there was an 8%-10% decrease in the rate of cancer detection. Similarly, as the prostate volume increased, the odds of obtaining a positive core also decreased (p = 0.039). there was no significant association between the lesion size and amount of cancer obtained on *** data showed that transrectal MRI-targeted biopsy cancer detection modestly decreased the lesion from the ultrasound probe and with a large prostate volume but could not prove that lesion volume was a significant predictor of the amount of cancer detected.

关键词： Prostate cancer Biopsy Magnetic resonance imaging CORES