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Marginal discrepancy and microleakage in crown-copings fabricated by three CAD/CAM systems: An <i>in vitro</i>study

Open Journal of Stomatology 2012年第3期2卷 163-169页

作者： Marcela Herrera Alfonso Catalán maritza flores Alejandra Martínez Department of Oral Pathology Faculty of Dentistry University of Concepción Concepción Chile Department of Public Health School of Medicine University of Concepción Concepción Chile Department of Restorative Dentistry Faculty of Dentistry University of Concepción Concepción Chile

The purpose of this study was to evaluate and compare the microleakage and marginal discrepancy of ceramic crown-copings fabricated by three different CAD/CAM systems. Material and methods: Thirty extracted premolars were prepared for complete all-ceramic crowns with: total convergence 10-degree, 2 mm occlusal reduction, 4.5 mm height, 1.3 mm circular reduction and chamfer marginal preparation. They were divided into three groups and each group (n = 10) received a ceramic crown-coping fabricated by one of three CAD/CAM systems: Procera, KaVo Everest and Cerec inLab. The copings were cemented with Panavia F 2.0. After thermal cycling, the teeth were immersed in 2% basic fuchsine dye for 24 hours. Microleakage was scored using a five-point scale and evaluated under a stereomicroscope at ×18. Marginal discrepancies were assessed with scanning electronic microscope at ×150, with measurements at 50 different points. Data were subjected to a chisquare test, Kolmogorov-Smirnov test and using Rho Spearman’s correlation test (P 0.05). No significant differences were found in marginal discrepancies for the Procera (62.58 ± 8.98 μm) and KaVo Everest systems (65.54 ± 18.56 μm), (P = 0.941). Significant differences were found for Cerec inLab (132.18 ± 27.75 μm) compared with Procera and KaVo Everest (P = 0.0001). No correlation between the marginal discrepancies and microleakage for the three CAD/CAM crown-copings systems. Conclusions: Cerec inLab CAD/CAM crown-copings showed significantly higher values for microleakage and marginal discrepancy in comparison with Procera and KaVo Everest CAD/CAM crown-copings.

关键词： CAD/CAM Copings Microleakage Marginal Discrepancy Panavia F.2

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Endoscopic Sphinterotomy in Patients with Mild Acute Biliary Pancreatitis, in <i>Situ</i>Gallbladder and Alithiasic Bile Duct: Is It Justified?

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Open Journal of Gastroenterology 2021年第7期11卷 118-133页

作者： Mario Anselmi Méndez Ana María Gemmato Pascazi Julio Salgado Oyarzún maritza flores Opazo General and Digestive Surgery Department School of Medicine University of Concepción Concepcion Chile Public Health Department School of Medicine University of Concepción Concepcion Chile

Objective: To compare the long-term results of the treatment of mild acute biliary pancreatitis in patients with gallbladder in situ, without stones in the bile duct, treated by cholecystectomy, and endoscopic sphincterotomy (ES) versus simple cholecystectomy in the prevention of recurrence of this pathology. Material and Methods: Between May 2008 and December 2012, 110 consecutive patients with a mild acute biliary pancreatitis (ABP) were prospectively studied. None had undergone cholecystectomy, and choledocholithiasis was ruled out by ERCP. Two groups of patients were created and randomized: Group I (n = 55) who underwent ERCP plus ES and Group II (n = 55) only had diagnostic ERCP. Patients were then referred for cholecystectomy. Follow up was completed in 101 patients. Group I was made up of 53 patients and Group II had 48 similar characteristics. Patients were followed for an average of 105 months. At the end of the follow-up, 12 (22.6%) from Group I and 6 (12.5%) from Group II (p = 0.143) remained with the gallbladder in situ. Results: There were 53 patients in Group I (100%). Only 42 (87.5%) of those in Group II evolved without biliopancreatic complications (p = 0.0096). In the latter, 6 (12.5%) wer

关键词： Pancreatitis Endoscopic Sphincterotomy

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Role of N-formyl peptide receptor 2 in germinal matrix hemorrhage:an intrinsic review of a hematoma resolving pathway

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Neural Regeneration Research 2024年第2期19卷 350-354页

作者： Jerry flores Jiping Tang Department of Physiology&Pharmacology Loma Linda University School of MedicineLoma LindaCAUSA

Germinal matrix hemorrhage is one of the leading causes of morbidity,mortality,and acquired infantile hydrocephalus in preterm infants in the United States,with little progress made in its clinical *** clots have been shown to elicit secondary brain injury after germinal matrix hemorrhage,by disrupting normal cerebrospinal fluid circulation and absorption after germinal matrix hemorrhage causing post-hemorrhagic hydrocephalus *** evidence suggests that rapid hematoma resolution is necessary to improve neurological outcomes after hemorrhagic *** articles have demonstrated the beneficial effects of stimulating the polarization of microglia cells into the M2 phenotype,as it has been suggested that they play an essential role in the rapid phagocytosis of the blood clot after hemorrhagic models of stroke.N-formyl peptide receptor 2(FPR2),a G-protein-coupled receptor,has been shown to be neuroprotective after ***2 activation has been associated with the upregulation of phagocytic macrophage clearance,yet its mechanism has not been fully *** literature suggests that FPR2 may play a role in the stimulation of scavenger receptor *** receptor CD36 plays a vital role in microglia phagocytic blood clot clearance after germinal matrix ***2 has been shown to phosphorylate extracellular-signal-regulated kinase 1/2(ERK1/2),which then promotes the transcription of the dual-specificity protein phosphatase 1(DUSP1)*** this review,we present an intrinsic outline of the main components involved in FPR2 stimulation and hematoma resolution after germinal matrix hemorrhage.

关键词： AnxA1 FPR2 GMH hematoma resolution hemorrhagic stroke M1 M2 microglia polarization microglia phagocytosis

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Remediation of amide pesticide-polluted soils by combined solarization and ozonation treatment

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Pedosphere 2024年第3期34卷 641-651页

作者： Isabel GARRIDO Carmen MMARTINEZ Pilar flores Pilar HELLIN Fulgencio CONTRERAS Jose FENOLL Department of Sustainability and Quality Group of Fruit and Vegetable Products Instituto Murciano de Investigacion y Desarrollo Agrario y MedioambientalLa Alberca 30150(Spain)

Agriculture has a close relationship with nature,but it can also be the source of negative and permanent environmental *** use of pesticides in modern agriculture is a common practice,but their side effects on the environment cannot be *** this study,we evaluated a combination of solarization and ozonation techniques for the elimination of six amide pesticides(boscalid,chlorantraniliprole,cyflufenamid,fluopyram,napropamide,and propyzamide)in *** experiments were performed with four different soils to assess the efficiency of this methodology at different soil temperatures and ozone dosages under laboratory conditions,and then a greenhouse pot experiment was conducted under controlled conditions during *** days after the onset of the experiments,higher degradation percentages of amide pesticides were observed in ozonized soils than in other treated soils,particularly when ozone was applied at 10 cm soil *** results show that the utilization of ozonation,along with solarization,represents a valid method for degrading residues of the studied pesticides and suggest that this combined technology may be a promising tool for remediating pesticide-polluted soils.

关键词： intermediate ozone pesticide degradation pesticide residue polyethylene film remediation technique

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Polyoxidovanadates a new therapeutic alternative for neurodegenerative and aging diseases

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Neural Regeneration Research 2024年第3期19卷 571-577页

作者： Sonia Irais Gonzalez-Cano Gonzalo flores Jorge Guevara Julio Cesar Morales-Medina Samuel Treviño Alfonso Diaz Faculty of Chemical Sciences Benemerita Autonomous University of PueblaPueblaMexico Institute of Physiology Benemerita Autonomous University of PueblaPueblaMexico Department of Biochemistry Faculty of MedicineNational Autonomous University of MexicoMexico CityMexico Animal Reproduction Research Center CINVESTAV-Autonomous University of TlaxcalaTlaxcalaMexico

Aging is a natural phenomenon characterized by a progressive decline in physiological integrity,leading to a deterioration of cognitive function and increasing the risk of suffering from chronic-degenerative diseases,including cardiovascular diseases,osteoporosis,cancer,diabetes,and *** is considered the major risk factor for Parkinson’s and Alzheimer’s disease ***,diabetes and insulin resistance constitute additional risk factors for developing neurodegenerative ***,no treatment can effectively reverse these neurodegenerative ***,some antidiabetic drugs have opened the possibility of being used against neurodegenerative *** the previous framework,Vanadium species have demonstrated a notable antidiabetic *** research group evaluated polyoxidovanadates such as decavanadate and metforminium-decavanadate with preventive and corrective activity on neurodegeneration in brain-specific areas from rats with metabolic *** results suggest that these polyoxidovanadates induce neuronal and cognitive restoration *** review aims to describe the therapeutic potential of polyoxidovanadates as insulin-enhancer agents in the brain,constituting a therapeutic alternative for aging and neurodegenerative diseases.

关键词： Alzheimer’s disease antidiabetic brain cognition diabetes insulin neurodegeneration neuroinflammation oxidative stress Vanadium species

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A Hybrid Model for Improving Software Cost Estimation in Global Software Development

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Computers, Materials & Continua 2024年第1期78卷 1399-1422页

作者： Mehmood Ahmed Noraini B.Ibrahim Wasif Nisar Adeel Ahmed Muhammad Junaid Emmanuel Soriano flores Divya Anand Faculty of Computer Science and Information Technology Universiti Tun Hussein Onn Malaysia Parit RajaBatu Pahat86400Malaysia Department of Computer Science COMSATS University Wah Cantt CampusIslamabad47010Pakistan Department of Information Technology The University of HaripurKhyber Pakhtunkhwa22620Pakistan Engineering Research Innovation Group Universidad Europea del AtlanticoSantander39011Spain

Accurate software cost estimation in Global Software Development(GSD)remains challenging due to reliance on historical data and expert *** models,such as the Constructive Cost Model(COCOMO II),rely heavily on historical and accurate *** addition,expert judgment is required to set many input parameters,which can introduce subjectivity and variability in the estimation ***,there is a need to improve the current GSD models to mitigate reliance on historical data,subjectivity in expert judgment,inadequate consideration of GSD-based cost drivers and limited integration of modern technologies with cost *** study introduces a novel hybrid model that synergizes the COCOMO II with Artificial Neural Networks(ANN)to address these *** proposed hybrid model integrates additional GSD-based cost drivers identified through a systematic literature review and further vetted by industry *** article compares the effectiveness of the proposedmodelwith state-of-the-artmachine learning-basedmodels for software cost *** the NASA 93 dataset by adopting twenty-six GSD-based cost drivers reveals that our hybrid model achieves superior accuracy,outperforming existing *** findings indicate the potential of combining COCOMO II,ANN,and additional GSD-based cost drivers to transform cost estimation in GSD.

关键词： Artificial neural networks COCOMO II cost drivers global software development linear regression software cost estimation

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Design,Synthesis,and Applications of Mesoporous Covalent Organic Frameworks

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CCS Chemistry 2024年第1期6卷 57-68页

作者： Niyati Arora Cassandra flores Milinda C.Senarathna Christina M.Thompson Ronald A.Smaldone Department of Chemistry and Biochemistry University of TexasDallasRichardsonTexas 75080

Covalent organic frameworks(COFs)are highly ordered and permanently porous organic polymers that can be classified as two-dimensional or *** tunable design and crystalline order endow a range of pore sizes,shapes,functions,and applications that differentiate them from other *** COF pore sizes and shapes rely on the geometry of the monomers and dynamic covalent chemistry,while the stacking of the sheets relies on noncovalent *** tunability allows for post-modification or the incorporation of additional functional groups for the reinforcement by various noncovalent *** limits of mesoporous COFs are still being investigated,with the design rules continuing to *** we report a comprehensive review of mesoporous COFs,explore strategies for large pore reinforcement,highlight structural design and features,elucidate their various functions and applications,discuss fundamental challenges faced that need to be addressed,and predict future directions.

关键词： covalent organic frameworks mesoporous supramolecular chemistry polymers pore size

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Effect of Senescence Retardants on the Quality of Persian Lime Fruits

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Phyton-International Journal of Experimental Botany 2024年第8期93卷 1805-1818页

作者： Rafael Ariza-flores Rafael Ambriz-Cervantes Pedro Cadena-Iñiguez Luis A.Gálvez-Marroquín Miguel A.Cano-García National Institute of Forestry Agriculture and Livestock Research(INIFAP)South Pacific Regional CenterSanto Domingo Barrio BajoVilla de EtlaOaxaca68200México National Institute of Forestry Agriculture and Livestock Research(INIFAP)Zacatepec Research StationZacatepecMorelos62780México National Institute of Forestry Agriculture and Livestock Research(INIFAP)Central Chiapas Research StationOcozocoautlaChis29140México National Institute of Forestry Agriculture and Livestock Research(INIFAP)Oaxaca Central Valley Research StationSanto Domingo Barrio BajoVilla de EtlaOaxaca68200México

The objective of this study consisted of evaluating the effect of the application of chitosan(Q),1-methylcyclopropene(1-MCP)under two controlled temperatures on some physical,physiological,and chemical parameters contributing to the quality of Persian lime Citrus latifolia *** treatments were evaluated,resulting from the combination of four senescence retardant applications(Q,1-MCP,1-MCP+Q,and without application)on fruits stored at two temperatures(12/20℃.Epidermis color(luminosity,chromaticity,and hue),fruit appearance,respiration,weight loss,total juice content,total soluble solids,and titratable acidity were registered during the *** results indicate that the 1-MCP and Q combination favored fruit postharvest quality conditions such as reducing respiration rate;maintaining fruit good appearance,turgidity,and brighter fruit chromaticity;fruits treated with chitosan and stored at 12℃,favored total soluble *** the other hand,Variables such as weight loss,juice content,acidity,phenols,flavonoids,antioxidant activity,and hue values were favored by a 12℃ storing temperature regardless of the *** general,the use of modified atmospheres,senescence retardants,and refrigeration as postharvest methods,can increase Persian lime shelf life.

关键词： Citrus latifolia quality conservation organic alternatives

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Non-Darcy Flow in Molding Sands

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Open Journal of Applied Sciences 2024年第4期14卷 976-982页

作者： Miguel A. Barron-Meza Joan Reyes-Miranda Daniel flores-Sanchez Departamento de Materiales Universidad Autonoma Metropolitana Azcapotzalco Ciudad de Mexico Mexico

Darcy’s law is widely used to describe the flow in porous media in which there is a linear relationship between fluid velocity and pressure gradient. However, it has been found that for high numbers of Reynolds this law ceases to be valid. In this work, the Ergun equation is employed to consider the non-linearity of air velocity with the pressure gradient in casting sands. The contribution of non-linearity to the total flow in terms of a variable defined as a non-Darcy flow fraction is numerically quantified. In addition, the influence of the shape factor of the sand grains on the non-linear flow fraction is analyzed. It is found that for values of the Reynolds number less or equal than 1, the contribution of non-linearity for spherical particles is around 1.15%.

关键词： Darcy’s Law Molding Sands Non-Darcy Flow Reynolds Number Shape Factor

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Urban Soil Compaction Remediation by Shallow Tillage and Compost in Hydroseeded Lawn

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Open Journal of Soil Science 2024年第7期14卷 399-415页

作者： James Jihoon Kang Adam flores Engil Isadora Pujol Pereira Jungseok Ho School of Earth Environmental and Marine Sciences University of Texas Rio Grande Valley Edinburg Texas USA Environmental Health and Safety University of Texas Health San Antonio San Antonio Texas USA Department of Civil Engineering University of Texas Rio Grande Valley Edinburg Texas USA

Construction activities often involve removal of topsoil and compaction of the exposed soil by heavy equipments. Such compacted soils with low organic matter can lead to low infiltration and poor vegetation establishment. The objective of this study was to investigate the efficacy of tillage (shallow till) and compost on soil physical and biological properties in a hydroseeded lawn as a post-construction best management practice for soil compaction remediation. The experimental site received a total of four land treatments in five replicated trials and it was hydroseeded with common Bermuda grass: 1) No Tillage + Compost (NT-C), 2) No Tillage + No Compost (NT-NC;control), 3) Tillage + Compost (T-C), and 4) Tillage + No Compost (T-NC). Bulk density (BD), infiltration rate (IR), and wet aggregate stability (WAS) in each plot were measured to assess soil physical properties while soil organic matter (SOM) and enzyme activity (β-glucosidase, acid-phosphatase, and alkaline-phosphatase) were measured for soil biological properties. Over a 15-months of monitoring period, the shallow tillage loosened the soil initially, but its effect on BD without compost was diminished to control plot level (NT-NC) within 4 months after hydroseeding. Both tillage and compost led to an increase in IR, and it remained higher than control by 2 - 3 times throughout the observation period. The WAS and β-glucosidase activity decreased in tilled plot unless there was compost application. Turfgrass showed greener leaves and aggregated roots in the compost-amended plots (NT-C and T-C). Our results suggest that compost application plays a key role in improving soil physical and biological properties in hydroseeded lawns from construction sites.

关键词： Compaction Compost Infiltration Soil Organic Matter Soil Enzyme Tillage Wet Aggregate Stability

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