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Functional traits:the pathways to riverine plant resistance in times of hydropeaking

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Ecological Processes 2023年第1期12卷 884-915页

作者： Alejandro Baladrón María Dolores bejarano Isabel Boavida CERIS Civil Engineering Research and Innovation for SustainabilityInstituto Superior TécnicoUniversidade de LisboaAv.Rovisco Pais1049-001 LisbonPortugal Natural Resources Department Universidad Politécnica de Madrid(UPM)Calle JoséAntonio Novais1028040 MadridSpain

Hydropeaking,which refers to rising or falling discharges caused by the turning on or off of hydro-turbines to generate electricity,is a topic of growing interest due to its impact on fluvial *** date,most hydropeaking studies have focused on the impact of peak fluctuations on invertebrate and fish communities,but little attention has been paid to its impact on riverine plants and how functional traits may make them resistant to *** performed a review to assess how a set of 32 plant functional traits can be expressed in riverine plant species,and found evidence of how such expression affects their capacity to cope with common sources of hydropeaking disturbance(i.e.,inundation,fast water drawdown,and rapid water fluctuations linked to up-ramping and down-ramping hydropeaking operations).The information here presented can simplify the evaluation of impacts on riverine plant communities worldwide,as well as to detect suitable species to successfully restore rivers affected by hydropower production.

关键词： Drought Flooding Waterlogging Hydropeaking Plant trait Riverine vegetation

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Boosting proteolytic pathways as a treatment against glycation-derived damage in the brain?

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Neural Regeneration Research 2022年第2期17卷 320-322页

作者： Allen Taylor Eloy bejarano Laboratory for Nutrition and Vision Research USDA Human Nutrition Research Center on AgingTufts UniversityBostonMAUSA Departments of Chemical and Molecular Biology and Ophthalmology Tufts University School of MedicineBostonMAUSA Friedman School of Nutrition and Science Policy Tufts UniversityBostonMAUSA School of Health Sciences and Veterinary School Universidad Cardenal Herrera-CEUCEU UniversitiesMoncadaValenciaSpain

The worldwide adaptation of a Western lifestyle is associated with the increased consumption of high glycemia diets and an increased prevalence of obesity, metabolic syndrome, and diabetes.

关键词： damage obesity prevalence

Targeting autophagy by polyphenols to prevent glycative stress-toxicity in the brain

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Neural Regeneration Research 2024年第5期19卷 941-942页

作者： Alejandro Ponce-Mora Eloy bejarano Department of Biomedical Sciences School of Health Sciences and Veterinary SchoolUniversidad Cardenal Herrera-CEUCEU UniversitiesValenciaSpain

Glycative stress-a pathological hub in brain dysfunction:The nervous system is an intricate network that requires precise and complex *** recent years,growing evidence highlights the detrimental impact of glycative stress on brain homeostasis,which disables a network of vital processes,necessary for optimal function(Gómez et al.,2021).

关键词： homeostasis stress

Numerical modeling of nutrient transport to assess the agricultural impact on the trophic state of reservoirs

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International Soil and Water Conservation Research 2023年第1期11卷 197-212页

作者： Franklin Torres-bejarano Jesús García-Gallego Javier Salcedo-Salgado Department of Environmental Engineering University of CordobaCarrera 6 No.77-305230002MonteriaColombia Environmental Engineering Program University of CordobaCarrera 6 No.77-305230002MonteriaColombia

A trophic state increase relates to surface water bodies nutrient enrichment,due to the chemical products used such as fertilizers in agriculture and residues from cattle raising *** research consists of nutrient transport numerical modeling to analyze the Betancíreservoir trophic state in Colombia;Water samples were collected to analyze total nitrogen,total phosphorus,ammonia,nitrates,nitrites,phosphates,chlorophyll-a,dissolved oxygen,BOD,COD,suspended solids,and water *** water quality model MOHID Studio was implemented and after its calibration,scenarios of increase and decrease of nutrients and inflows to the reservoir through its main tributaries were simulated to reproduce the agricultural activity changes in the basin and the effects that would have on the reservoir's trophic state dynamics;Therefore,the Carlson Trophic Status Index was calculated for each *** results show that variations in total nitrogen concentration and increased inflows present short-term consequences on the reservoir's trophic *** the incoming total nitrogen con-centrations by 100%causes the reservoir to change from a light eutrophic to a hypereutrophic *** results of this research provide a starting tool to water resources integrated management in reservoirs.

关键词： Environmental modeling Trophic state index Nutrient transport Eutrophication Water pollution

Transthoracic echo: A sensitive tool for detecting cardiac extension of renal cell carcinoma?

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World Journal of Clinical Cases 2014年第8期2卷 377-379页

作者： Michelle bejarano Yara L Cameron Theodore C Koutlas Assad Movahed Department of Cardiovascular Sciences East Carolina Heart Institute and Brody School of MedicineGreenvilleNC 27834United States

Renal cell carcinoma is a common urological malignancy with the unique ability to invade the inferior vena cava(IVC) and to extend into the right atrium of the heart. Of those with Renal cell carcinoma only 4%-25% are found to have IVC invasion and of those only 2%-10% extend into the right atrium. If treated surgically, extension of tumor thrombus is not a determinant of survival; therefore it is imperative to determine the presence and extent of tumor thrombus in order to determine surgical approach and tumor resection. To date this has been primarily accomplished by magnetic resonance imaging and computed tomography. We present a case of 61 years old African American woman in which transthoracic echocardiography provided a more accurate determination/characterization of the presence and degree of tumor thrombus and extension.

关键词： Renal cell carcinoma Tumor thrombus Cardiac extension Right atrial mass

Arabidopsis NahG Plants as a Suitable and Efficient System for Transient Expression using Agrobacte#um tumefaciens

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Molecular Plant 2017年第2期10卷 353-356页

作者： Tábata Rosas-Díaz Pepe Cana-Quijada Vitor Amorim-Silva Miguel A. Botella Rosa Lozano-Durán Eduardo R. bejarano Departamento de Biología Celular Genética y Fisiología Instituto de Hortofruticultura Subtropical y Mediterránea “La Mayora” Universidad de Málaga-Consejo Superior de Investigaciones Científicas (IHSM-UMA-CSIC) Universidad de Málaga Campus Teatinos 29071 Málaga Spain Shanghai Center for Plant Stress Biology (PSC) Shanghai Institutes of Biological Sciences Chinese Academy of Sciences Shanghai 201602 China Departamento de Biología Molecular y Bioquimica Instituto de Hortofruticultura Subtropical y Mediterránea “La Mayora” Universidad de Málaga-Consejo Superior de Investigaciones Científicas (IHSM-UMA-CSIC) Universidad de Málaga Campus Teatinos 29071 Málaga Spain

Dear Editor Research in molecular plant biology has largely benefitted from technologies allowing exogenous gene expression. While the generation of stable transgenic lines is required in some cases, transient transfo... 详细信息

关键词： Suitable Transient tumefaciens

Benign course of residual inflammation at end of treatment of liver transplant recipients after sofosbuvir based therapy

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World Journal of Hepatology 2022年第3期14卷 602-611页

作者： Bahaaeldeen Ismail Karim M Benrajab Pablo bejarano Phillip Ruiz Debbie Sears Andreas Tzakis Xaralambos Bobby Zervos Division of Digestive Diseases and Nutrition University of Kentucky College of MedicineLexingtonKY 40536United States Department of Pathology Cleveland Clinic FloridaWestonFL 33331United States Department of Pathology University of Miami Miller School of MedicineMiamiFL 33136United States Department of Liver Transplant Cleveland Clinic FloridaWestonFL 33331United States

BACKGROUND Persistent inflammation on histology after successful hepatitis C(HCV)treatment has been ***,data regarding the long-term impact in liver transplant recipients is limited,particularly after using direct-acting antiviral(DAA)*** To evaluate the impact of successful treatment with DAAs on histological changes and occult HCV and to describe the clinical course of residual inflammation in liver transplant *** We conducted a case series of 13 chronic HCV infected liver transplant recipients successfully treated with DAAs between December 2013 and May *** patients were treated for 24 wk and had non-detectable serum HCV RNA by the time of *** patients with at least one liver biopsy at or after treatment were *** examined liver biopsies for evidence of residual inflammation and the presence of intrahepatic HCV *** Persistent inflammation was seen in 12/13 patients on end of treatment *** was still seen in the available five follow-up biopsies(range 38-48 wk after the end of treatment).Intrahepatic HCV RNA was undetectable in all *** patients had preserved graft function for a mean follow-up of 2.5 years,except one that developed chronic *** After successful HCV treatment with DAAs,liver transplant recipients may have persistent inflammation on biopsy without evidence of intracellular *** clinical outcome remained favorable in most *** studies with a larger number and longer follow-up are needed to establish the implication of this finding on long-term graft function.

关键词： Immunosuppression Liver transplantation Recurrent hepatitis C Sustained virologic response Interferon

The transcriptional regulator JAZ8 interacts with the C2 protein from geminiviruses and limits the geminiviral infection in Arabidopsis

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Journal of Integrative Plant Biology 2023年第7期65卷 1826-1840页

作者： Tabata Rosas-Diaz Pepe Cana-Quijada Mengshi Wu Du Hui Gemma Fernandez-Barbero Alberto PMacho Roberto Solano Araceli GCastillo Xiao-Wei Wang Rosa Lozano-Duran Eduardo R.bejarano Departamento de Biología Celular Genética y FisiologíaFacultad de CienciasInstituto de Hortofruticultura Subtropical y Mediterránea“La Mayora”(IHSM‐UMA‐CSIC)Universidad de MálagaMálagaSpain Shanghai Center for Plant Stress Biology CAS Center for Excellence in Molecular Plant SciencesChinese Academy of SciencesShanghai 201602China Institute of Insect Sciences Zhejiang UniversityHangzhou 310058China Departamento de Genética Molecular de Plantas Centro Nacional de Biotecnología‐Consejo Superior de Investigaciones CientíficasMadrid 28049Spain Department of Plant Biochemistry Centre for Plant Molecular BiologyEberhard Karls UniversityTübingen D‐72076Germany

Jasmonates(JAs) are phytohormones that finely regulate critical biological processes, including plant development and defense. JASMONATE ZIM-DOMAIN(JAZ) proteins are crucial transcriptional regulators that keep JA-responsive genes in a repressed state. In the presence of JA-Ile, JAZ repressors are ubiquitinated and targeted for degradation by the ubiquitin/proteasome system,allowing the activation of downstream transcription factors and, consequently, the induction of JA-responsive genes. A growing body of evidence has shown that JA signaling is crucial in defending against plant viruses and their insect vectors. Here, we describe the interaction of C2proteins from two tomato-infecting geminiviruses from the genus Begomovirus, tomato yellow leaf curl virus(TYLCV) and tomato yellow curl Sardinia virus(TYLCSaV), with the transcriptional repressor JAZ8 from Arabidopsis thaliana and its closest orthologue in tomato, SlJAZ9. Both JAZ and C2proteins colocalize in the nucleus, forming discrete nuclear speckles. Overexpression of JAZ8did not lead to altered responses to TYLCV infection in Arabidopsis;however, knock-down of JAZ8 favors geminiviral infection. Low levels of JAZ8 likely affect the viral infection specifically,since JAZ8-silenced plants neither display obvious developmental phenotypes nor present differences in their interaction with the viral insect vector. In summary, our results show that the geminivirus-encoded C2 interacts with JAZ8 in the nucleus, and suggest that this plant protein exerts an anti-geminiviral effect.

关键词： C2 protein geminivirus jasmonates JAZ8 transcriptional repressor TYLCV

Portal vein arterialization in 25 liver transplant recipients:A Latin American single-center experience

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World Journal of Transplantation 2024年第2期14卷 135-147页

作者： Nicolas Andres Cortes-Mejia Diana Fernanda bejarano-Ramirez Juan Jose Guerra-Londono Diego Rymel Trivino-Alvarez Raquel Tabares-Mesa Alonso Vera-Torres Division of Anesthesiology Critical Care Medicineand Pain MedicineThe University of Texas MD Anderson Cancer CenterHoustonTX 77030United States Transplant and Hepatobiliary Surgery Department Fundacion Santa Fe de BogotaBogota 110111Colombia General Surgery Department Fundacion Santa Fe de BogotaBogota 110111Colombia

BACKGROUND Portal vein arterialization(PVA)has been used in liver transplantation(LT)to maximize oxygen delivery when arterial circulation is compromised or has been used as an alternative reperfusion technique for complex portal vein thrombosis(PVT).The effect of PVA on portal perfusion and primary graft dysfunction(PGD)has not been *** patients receiving PVA and LT at the Fundacion Santa Fe de Bogota between 2011 and 2022 were *** account for the time-sensitive effects of graft perfusion,patients were classified into two groups:prereperfusion(pre-PVA),if the arterioportal anastomosis was performed before graft revascularization,and postreperfusion(post-PVA),if PVA was performed *** pre-PVA rationale contemplated poor portal hemodynamics,severe vascular steal,or ***-PVA was considered if graft hypoperfusion became *** interventions were attempted before PVA.

关键词： Liver transplantation Portal vein arterialization Arteriovenous anastomoses Portal hypertension Portal vein thrombosis Spontaneous portosystemic shunts Vascular steal phenomenon Primary graft dysfunction Early allograft dysfunction