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Journal of Agricultural Science and Technology(B) 2016年第6期6卷 387-399页

作者： Heriberto Garcia-Coronado Maria-Elena Baez-Flores Rosalba Troncoso-Rojas marisela rivera-dominguez Martin-Emesto Tiznado-Hernandez Coordinacion de Tecnologia de Alimentos de Origen Vegetal Centro de Investigacion en Alimentacion y Desarrollo A.C. (CLAD)Hermosillo Sonora CP 83304 Mexico Facultad de Ciencias Quimico Biol6gicas Universidad Autonoma de Sinaloa Culiacan Sinaloa CP 80013 Mexico Coordinacion de Ciencia de los Alimentos Centro de Investigacion en Alimentacion y Desarrollo A.C. (CLAD) HermosilloSonora CP 83304 Mexico

Genetic Stability of Cryopreserved Grapevine （Wtis vinifera L.） Genome by Vitrification Method

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Journal of Agricultural Science and Technology(B) 2016年第6期6卷 380-386页

作者： Maria Femanda Lazo Javalera Martin Ernesto Tiznado Hemandez Irasema Vargas Arispuro Miguel Angel Martinez Tellez Maria Auxiliadora Islas Osuna Miguel Angel Hemandez Ofiate marisela rivera dominguez Food Science Coordination Research Center for Food and Development Hermosillo Sonora 83000 Mexico Food Technology of Plant Origin Coordination Research Center for Food and Development Hermosillo Sonora 83000 Mexico

EEGbands: A Computer Program to Statistically Analyze Parameters of Electroencephalographic Signals

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Journal of Behavioral and Brain Science 2014年第7期4卷 308-324页

作者： Miguel Angel Guevara Araceli Sanz-Martin marisela Hernández-González Instituto de Neurociencias CUCBA Universidad de Guadalajara Guadalajara Jalisco México

The quantitative analysis of electroencephalographic activity (EEG) is a useful tool for the study of changes in brain electrical activity during cognitive and behavioral functions in several experimental conditions. Their recording and analysis are currently carried out primarily through the use of computer programs. This paper presents a computerized program (EEGbands) created for Windows operating systems using the Delphi language, and designed to analyze EEG signals and facilitate their quantitative exploration. EEGbands applies Rapid Fourier Transformation to the EEG signals of one or more groups of subjects to obtain absolute and relative power spectra. It also calculates both interhemispheric and intrahemispheric correlation and coherence spectra and, finally, applies parametrical statistical analysis to these spectral parameters calculated for wide frequency EEG bands. Unlike other programs, EEGbands is simple and inexpensive, and rapidly and precisely generates results files with the corresponding statistical significances. The efficacy and versatility of EEGbands allow it to be easily adapted to different experimental and clinical needs.

关键词： EEG Correlation EEG Coherence Relative Power Absolute Power EEG Software EEG Signal Analysis

EEGcorco: a computer program to simultaneously calculate and statistically analyze EEG coherence and correlation

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Journal of Biomedical Science and Engineering 2011年第12期4卷 774-787页

作者： Miguel Angel Guevara marisela Hernández-González Araceli Sanz-Martin Claudia Amezcua 不详

EEGcorco is a computer program designed to analyze the degree of synchronization between two electroencephalographic signals (EEG) by mean the analysis of correlation and coherence index. The correlation and coherence values permit the quantitative determination of the similarity among EEG signals from homologous areas of the cerebral hemispheres (interhemispheric), and among localized areas within one cerebral hemisphere (intrahemispheric). EEG coherence is a function of frequency;thus it is commonly presented in a spectral manner (coherence values in every frequency of the spectrum), in contrast, the correlation function has been employed mainly to search periodic components of bioelectrical signals, and normally appears as punctual values defined in time, hence it is not common calculate correlation spectra. EEGcorco offers an easy and novel way to calculate correlation spectra by mean the application of the Fast Fourier Transformation (FFT) to digitized EEG signals. Both, correlation and coherence spectra are obtained in both independent frequencies and frequencies grouped in wide bands. Moreover, the program applies parametric statistical analyses to those coherence and correlation spectra also, for each individual frequency and for the frequencies grouped in bands. The program functions on any PC-compatible computer equipped with a Pentium or superior processor and a minimum of 512 Mb of RAM memory (though the higher the capacity the better). The space required on the hard disk depends on the signals to be analyzed, as the output takes the form of files in text format that occupy very little space. The program has been elaborated completely in the Delphi environment for the Windows operating system. The efficacy and versatility of EEGcorco allow it to be easily adapted to different experimental and clinical needs.

关键词： EEG EEG Coherence EEG Correlation

Electroencephalographic Correlates of Sexual Arousal Induced by Sexually-Explicit Reading in Human Females

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Journal of Behavioral and Brain Science 2018年第11期8卷 599-614页

作者： Miguel Angel Guevara Carolina Gomez-Navarro Claudia Amezcua-Gutierrez marisela Hernandez-Gonzalez Anders Agmo Institute of Neuroscience CUCBAUniversity of GuadalajaraGuadalajaraJaliscoMexico Psychology Department Tromso UniversityTromsoNorway

This study explored the cortical functionality in young women while reading a sexually-explicit text. Electroencephalographic activity (EEG) was recorded in heterosexual women while reading either a sexually-explicit text or one with neutral content. Absolute power (AP) and the degree of EEG synchronization among the prefrontal, temporal and parietal cortices were analyzed for the different EEG bands. To evaluate sexual arousal, valence and general activation, Likert-type and Manikin scales were applied. Subjects scored the sexually-explicit text as more pleasurable, and reported greater general activation and sexual arousal than while reading the neutral one. During reading of the sexually-explicit text only, they showed a higher AP in the beta and gamma bands in temporal areas in both hemispheres, and in the theta band in parietal ones, with a lower degree of EEG synchronization between prefronto-temporal areas in the fast bands. Results show that both hemispheres were activated in these sexually-aroused women. The low bilateral synchronization between prefrontal and temporal regions indicates the independent functionality of these cortices, which could be a requirement for inducing and maintaining sexual arousal during reading of sexually-explicit texts in women. These data should broaden our knowledge of the cortical mechanisms that underlie sexual arousal in women.

关键词： Sexual Arousal EEG Sexually-Explicit Reading Erotic Reading Women

Reversing gastric mucosal alterations during ethanol-induced chronic gastritis in rats by oral administration of Opuntia ficus-indica mucilage

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World Journal of Gastroenterology 2006年第27期12卷 4318-4324页

作者： Ricardo Vázquez-Ramírez marisela Olguín-Martínez Carlos Kubli-Garfias Rolando Hernández-Mu■oz Depto.de Biología Celular y Fisiología Instituto de Investigaciones Biomédicas. Universidad Nacional Autónoma de México. Apdo. Postal 70-243México D.F. 04510Mexico Depto.de Biología Celular Instituto de Fisiología Celular. Universidad Nacional Autónoma de México. Apdo. Postal 70-243México D.F. 04510Mxico Depto. de Biología Celular Institute de Fisiología Celular. Universidad Nacional Autónoma de México. Apdo. Postal 70-243México D.F. 04510Mxico

瞄准：为了学习，粘液的效果在在老鼠导致乙醇的胃炎愈合上从仙人掌属植物 ficus-indica (仙人掌科) 的叶状枝获得了。方法：长期的胃粘膜损害与粘液被对待(5 mg/kg 每天) 在它被乙醇导致以后。类脂化合物作文， 5'-nucleotidase (联系... 详细信息

瞄准：为了学习，粘液的效果在在老鼠导致乙醇的胃炎愈合上从仙人掌属植物 ficus-indica (仙人掌科) 的叶状枝获得了。方法：长期的胃粘膜损害与粘液被对待(5 mg/kg 每天) 在它被乙醇导致以后。类脂化合物作文， 5'-nucleotidase (联系膜的 ectoenzyme ) 的活动和在胃粘膜的血浆膜的 lactate 和醇脱氢酶的 cytosolic 活动是坚定的。从试验性的组的胃的样品的组织学的研究被包括。结果：乙醇得到了表面上皮的损失和 polymorphonuclear 的渗入描绘的胃炎的组织学的侧面。Phosphatidylcholine (PC ) 减少了，胆固醇内容在胃粘膜的质膜增加了。另外，当醇脱氢酶的活动减少了时， cytosolic 活动增加了。粘液的管理即时改正了这些酶的变化。事实上，粘液乐意地在胃粘膜的质膜加速了导致乙醇的组织学的改变和骚乱的恢复，显示出只有一个意义的反煽动性的效果。5'-nucleotidase 的活动在类脂化合物作文和胃的粘膜质膜的流动性与变化相关。结论：粘液的有益的行动似乎与损坏胃粘膜的质膜的稳定相关。在粘液之间的分子的相互作用单音的糖类和膜 phospholipids，主要 PC 和 phosphatidylethanolamine (PE ) ，可以是负责在长期的胃的粘膜以后在愈合的过程期间改变依附膜的蛋白质的活动的相关特征损坏。

关键词：胃黏膜慢性胃炎仙人掌黏液

Basolateral Amygdala Inactivation Reduces Sexual Motivation in Male Rats during Performance of a T-Maze Task with a Sexual Reward

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Journal of Behavioral and Brain Science 2014年第5期4卷 223-233页

作者： marisela Hernández-González Francisco Abelardo Robles Aguirre Miguel ángel Guevara Gina Lorena Quirarte Paulina Haro Magallanes Centro Universitario del Norte Universidad de Guadalajara Colotlán Jalisco México Instituto de Neurobiología Campus UNAM-UAQ Juriquilla Querétaro México Instituto de Neurociencias Universidad de Guadalajara Guadalajara Jalisco México

This study was aimed to determine the effect of amygdaline inactivation on the sexual motivation of male rats during a T-maze task with a sexual reward. Subjects were chronically implanted with two stainless-steel cannulae that enabled the infusion of tetrodotoxin, a sodium channel blocker, into the left and right basolateral amygdala (BLA). Animals were divided into 3 groups: saline (SS);TTX1 (tetrodotoxin at 2.5 ng);and TTX2 (tetrodotoxin at 5.0 ng). To induce a sexually-motivated state, all male rats were allowed to have an intromission with a receptive female before performing the T-maze task, after which their sexual motivation was evaluated during seven trials in which a receptive female was placed in one goal-box of the T-maze, and a non-receptive one in the other. Subjects were allowed an intromission as a sexual reward whenever they reached the goal-box containing the receptive female, but were returned to the start-box if they did not. At the end of the experiment, copulation until ejaculation was permitted. Both doses of TTX increased the time rats required to cross the maze stem during the final trials. In terms of sexual interaction, the high dose of TTX increased more markedly mount, intromission and ejaculation latencies and the number of mounts and intromissions. Overall, these results indicate that the BLA may play an important role in modulating sexual behavior, particularly in maintaining sexual motivation in successive trials in a T-maze task and during sexual interaction per se.

关键词： Basolateral Amygdala Sexual Motivation Sexual Reward T-Maze Tetrodotoxin Copulation Rats

Differential Effect of Acute Stress on Visuospatial Working Memory and Sexual Motivation in Male Rats

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Journal of Behavioral and Brain Science 2015年第7期5卷 221-230页

作者： marisela Hernández-González Enrique Hernández-Arteaga Mayra Linné Almanza-Sepúlveda Miguel ángel Guevara Instituto de Neurociencias Universidad de Guadalajara Guadalajara Jalisco México

Working memory is an executive function that is highly dependent on the functioning of the prefrontal cortex. Several studies using food or drink as rewards have demonstrated that rats are capable of performing tasks that involve working memory. Sexual behavior is another highly-rewarding, motivated behavior that has proven to be an efficient incentive in classical operant tasks. Considering that both sexual behavior and working memory are sensitive to the effects of stress, the aim of this study was to determine the effect of acute stress on visuospatial working memory during a sexually-motivated task (a nonmatching-to-sample task in a T-maze) in male rats. Thirty-two male Wistar rats were trained in the T-maze using sexual interaction (intromission and ejaculation) as a reinforcer during a 4-day training period (training sessions held every 4th day). On the basis of their performance, the rats were classified as good-learners (n = 12) and bad-learners (n = 20), and on the fifth day, 6 good-learners and 10 bad-learners were subjected to stress using the cold water immersion model (CWI, 15°C) for 15 minutes before they were evaluated in the T-maze. The remaining rats made up the control group (i.e., they performed the task without previous stress). Results showed that acute stress by CWI improved working memory in the bad-learners but did not affect the performance of the good-learners, although in both groups (good- and bad-learners) stress decreased the sexual motivation to perform the task. It is probable that the increased levels of corticosterone in the stress situation could activate glutamatergic transmission in the prefrontal cortex, thus facilitating working memory and, simultaneously, decreasing testosterone levels, which exerts a negative effect on sexual motivation in these male rats.

关键词： Stress Working Memory Sexual Behavior

Alcohol Suppresses the Electroencephalographic Response to Visual Erotic Stimuli in Young Men

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Journal of Behavioral and Brain Science 2012年第3期2卷 363-371页

作者： marisela Hernández-González Araceli Sanz-Martin Miguel ángel Guevara Claudia Amezcua-Gutiérrez Marina Ruiz Díaz Instituto de Neurociencias Universidad de Guadalajara Guadalajara México

Although the combination of alcohol and sex is frequently observed in human social interaction, many questions concerning alcohol’s effects on the processing of sexual stimuli and brain functionality remain unanswered. Erotic films eliciting sexual arousal in humans and affect electroencephalographic (EEG) activity. This study examines the effects of alcohol on cortical EEG activity in young men while viewing an erotic film. Heterosexual males participated in an independent alcohol/placebo group protocol. Thirty-five minutes after beverage ingestion, EEGs were recorded at prefrontal, temporal and parietal derivations in three conditions: baseline, and while watching erotic and neutral films. During the observation of erotic films, only the participants who drank the placebo beverage showed a decrease in alpha1 and an increase in the fast frequencies of the prefrontal regions, as well as a decrease in inter-prefrontal synchronization in the alpha and beta bands. Alcohol suppressed the prefrontal EEG changes associated with watching erotic visual stimuli without affect the sexual arousal. EEG data show that alcohol affecting the functioning of the prefrontal cortex, which could interfere with the adequate processing of visual erotic stimuli. These findings may contribute to improving our understanding of the brain mechanisms that underlie alcohol’s effects on the processing of sexual stimuli.

关键词： Alcohol Erotic Stimulation Sexual Arousal EEG Correlation Electroencephalogram

EEG Correlations during WCST Performance in Female Adolescents with Sexual Abuse-Related Post-Traumatic Stress Disorder

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Journal of Behavioral and Brain Science 2015年第7期5卷 239-250页

作者： Lucía Ester Rizo-Martínez Araceli Sanz-Martin Miguel ángel Guevara marisela Hernández-González Olga Inozemtseva Francisco Abelardo Robles-Aguirre Instituto de Neurociencias CUCBA Universidad de Guadalajara Guadalajara México Centro Universitario del Norte Universidad de Guadalajara Colotlán México

Child sexual abuse (CSA) survivors can present post-traumatic stress disorder (PTSD) and alterations in EEG activity and cognition. The aim of this study was to evaluate EEG correlations in female adolescents with CSA-related PTSD during performance of the Wisconsin Card-Sorting Test (WSCT). Inter- and intrahemispheric EEG correlations (INTERr and INTRAr) of those subjects were calculated at rest and during performance of WCST. On this task, the PTSD group obtained higher scores than the control group for the number of correct responses and failure to maintain set. In the between-groups comparisons, the PTSD group presented a higher INTERr between frontal areas in the gamma and slow bands, as well as a higher correlation in the delta band at Fp1-F3;however, this group presented a lower INTRAr between Fp1-P3 and Fp2-P4 in the theta and alpha1 bands. In the comparison between conditions, the PTSD group presented an increased correlation during execution of the WCST, mainly in the gamma band, while the control group showed a decrease of INTRAr in the slow bands. Results are discussed with respect to the influence of CSA- related PTSD on the development of cognition and functional connectivity in the brain.

关键词： Child Sexual Abuse Post-Traumatic Stress Disorder EEG Correlation WCST Adolescents