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控制理论与应用 1998年第6期15卷 831-841页

作者：刘万泉 Sreeram V. teo K.L. 高峰悉尼大学电子与信息系澳大利亚Curtin工程大学数理系西澳大学电机电子工程系

研究具有直接前馈的奇异分散系统．利用状态空间方法，我们导出了该系统通过静态输出反馈达到单通道R-可控与单通道R-可稳的条件．利用这些条件，我们研究了这类系统的分散极点配置问题与分散可稳性问题．本文的结果可用于研究带前馈的... 详细信息

研究具有直接前馈的奇异分散系统．利用状态空间方法，我们导出了该系统通过静态输出反馈达到单通道R-可控与单通道R-可稳的条件．利用这些条件，我们研究了这类系统的分散极点配置问题与分散可稳性问题．本文的结果可用于研究带前馈的奇异摄动分散系统．

关键词：奇异分散系统可控性反馈控制直接前馈控制

Robust time-delay estimation for nonlinear systems using inexact output

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Robust time-delay estimation for nonlinear systems using ine...

Telmisartan, ramipril, or both in high-risk Chinese patients： analysis of ONTARGET China data

第30届中国控制与决策会议

作者： Zhaohua Gong Chongyang Liu Meijia Han Kok Lay teo Yonghong Wu School of Mathematics and Information Science Shandong Technology and Business University School of Electrical Engineering Computingand Mathematical SciencesCurtin University

This paper considers time-delay estimation problem involving nonlinear dynamic systems using inexact system *** first propose a new robust time-delay formulation,in which the variance of the least-squares error function is minimized subject to a constraint specifying the sacrifice from the optimal expectation of the classical timedelay estimation ***,we show that the gradients of the cost and/or constraint functions in the classical and robust estimation problems can be computed by sequently solving the state system forward in time and auxiliary timedelay systems backward in *** this basis,new gradient-based optimization algorithms are developed to solve the estimation ***,a numerical example is used to verify the effectiveness of the proposed algorithms.

关键词： Nonlinear time-delay system time-delay estimation gradient computation numerical optimization

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Chinese Medical Journal 2011年第12期124卷 1763-1768页

作者： YU Li-tian ZHU Jun TAN Hui-qiong WANG Guo-gan Koon K. teo LIU Li-sheng Emergency Center Cardiovascular Institute and Fuwai Hospital Peking Union Medical College and Chinese Academy ofMedical Sciences Beijing 100037 China Hypertension Center Cardiovascular Institute and Fuwai Hospital Peking Union Medical College and Chinese Academy ofMedical Sciences Beijing 100037 China Population Health Research Institute McMaster University andHamilton Health Sciences Hamilton ON Canada

Background The results from the ONgoing Telmisartan Alone and in combination with Ramipril Global Endpoint Trial （ONTARGET） indicated that the angiotensin-receptor blocker telmisartan was not inferior to the angiotensin-converting-enzyme inhibitor ramipril in reducing the composite endpoint of cardiovascular death, myocardial infarction, stroke or hospitalization for congestive heart failure in high-risk patients, and telmisartan was associated with slightly superior tolerability. The combination of the two drugs was associated with more adverse events without an increase in benefit. This study aimed to analyze the data from ONTARGET obtained from a subgroup of patients enrolled in China and to evaluate the demographic and baseline characteristics, the compliance, efficacy, and safety of the different treatment strategies in randomized patients in China. Methods A total of 1159 high-risk patients were randomized into three treatment groups： with 390 assigned to receive 80 mg of telmisartan, 385 assigned to receive 10 mg of ramipril and 384 assigned to receive both study medications. The median follow-up period was 4.3 years. Results The mean age of Chinese patients was 65.6 years, 73.6% of patients were male. The proportion of patients with stroke/transient ischemic attacks at baseline in China was two times more than the entire study population （47.7% vs 20.9%）. In Chinese patients the proportion of permanent discontinuation of study medication due to cough was 0.5% in the telmisartan group, which was much less than that in the combination or the ramipril group. There were no significant differences in the incidence of primary outcome among three treatment groups of Chinese patients. More strokes occurred in Chinese patients than in the entire study population （8.5% vs. 4.5%）. Greater systolic blood pressure reduction （-9.8 mmHg）, and more renal function failure were noted in the combination treatment group than in the ramipril or telmisartan group （2.6% vs. 1.6% a

关键词： telmisartan ramipril, high-risk

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水对商业的影响——以新加坡为例

WTO经济导刊 2016年第4期 46-47页

作者： Justin teo

据外媒3月23日报道，联合国发布的数据显示，到了2025年，全球约有18亿人口面临绝对缺水的问题，约三分之二人口可能在用水紧张的条件下生活。无论是在《2030年可持续发展议程》，还是已超过130个国家签署的《巴黎协定》，都对水资源的... 详细信息

据外媒3月23日报道，联合国发布的数据显示，到了2025年，全球约有18亿人口面临绝对缺水的问题，约三分之二人口可能在用水紧张的条件下生活。无论是在《2030年可持续发展议程》，还是已超过130个国家签署的《巴黎协定》，都对水资源的保护和利用做出了承诺和目标。我国也在此间提出了雄心勃勃的计划，但具体应该怎么去推进？

关键词：新加坡商业可持续发展保护和利用数据显示联合国水资源人口

Infective crystalline keratopathy due to Citrobacter koseri

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Journal of Acute Disease 2021年第1期10卷 36-38页

作者： Lim Thiam-Hou Evelyn Li Min Tai Shamel Sonny teo Khairy Ibrahim Mohtar Department of Department of Ophthalmology and Visual Sciences School of Medical SciencesHealth Campus Universiti Sains Malaysia16150 Kubang KerianKelantanMalaysia

Rationale:Infectious keratopathy is an ocular emergency with the potential to cause irreversible ***'s concerns:A 63-year-old diabetic man presented with a 3-day history of painful red right *** had a history of multiple ocular surgeries in the affected eye without recent ocular ***:Infective crystalline keratopathy secondary to Citrobacter ***:Topical corticosteroids were discontinued,and dual topical antibiotic therapy of moxifloxacin 5%and gentamycin 0.3%were ***:Twelve hours after the start of treatment,the crystalline nature of the infiltrate disappeared,with enlargement of the epithelial *** antibiotic regime was continued and the lesion healed within a week of presentation with residual ***:Infective crystalline keratopathy classically presents with intrastromal branching fern-like opacities and minimal anterior segment inflammation in an immunosuppressed *** mainstay of management is corticosteroid discontinuation and the administration of empirical antibiotics until the results of the culture and sensitivity are *** Citrobacter-related cases,treatment may result in a suppurative appearance before healing of the lesion.

关键词： Infectious crystalline keratopathy Citrobacter koseri Gram-negative bacteria

Gastric peritoneal carcinomatosis-a retrospective review

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World Journal of Gastrointestinal Oncology 2017年第3期9卷 121-128页

作者： Hwee Leong Tan Claramae Shulyn Chia Grace Hwei Ching Tan Su Pin Choo David Wai-Meng Tai Clarinda Wei Ling Chua Matthew Chau Hsien Ng Khee Chee Soo Melissa Ching Ching teo Division of Surgical Oncology National Cancer Centre Singapore Dvision of Medical Oncology National Cancer Centre Singapore

AIM To characterize patients with gastric peritoneal carcinomatosis(PC) and their typical clinical and treatment course with palliative systemic chemotherapy as the current standard of *** We performed a retrospective electronic chart review of all patients with gastric adenocarcinoma with PC diagnosed at initial metastatic presentation between January 2010 and December 2014 in a single tertiary referral *** We studied a total of 271 patients with a median age of 63.8 years and median follow-up duration of 5.1 mo. The majority(n = 217, 80.1%) had the peritoneum as the only site of metastasis at initial presentation. Palliative systemic chemotherapy was eventually planned for 175(64.6%) of our patients at initial presentation, of which 171 were initiated on it. Choice of first-line regime was in accordance with the National Comprehensive Cancer Network Guidelines for Gastric Cancer Treatment. Thesepatients underwent a median of one line of chemotherapy, completing a median of six cycles in total. Chemotherapy disruption due to unplanned hospitalizations occurred in 114(66.7%), while cessation of chemotherapy occurred in 157(91.8%), with 42 cessations primarily attributable to PC-related complications. Patients who had initiation of systemic chemotherapy had a significantly better median overall survival than those who did not(10.9 mo vs 1.6 mo, P < 0.001). Of patients who had initiation of systemic chemotherapy, those who experienced any disruptions to chemotherapy due to unplanned hospitalizations had a significantly worse median overall survival compared to those who did not(8.7 mo vs 14.6 mo, P < 0.001).CONCLUSION Gastric PC carries a grim prognosis with a clinical course fraught with disease-related complications which may attenuate any survival benefit which palliative systemic chemotherapy may have to offer. As such, investigational use of regional therapies is warranted and required validation in patients with isolated PC to maximize their

关键词： Peritoneal carcinomatosis Gastric cancer

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全球最出色的新零售方式

中国制衣 2008年第5期 30-31页

作者： Angelia teo

为了让购物更有乐趣,零售商们现在越来越倾向于把商店的各个环节都仔细地加以研究,以改进商品展示和销售的方式。体验式销售Glbbetrotter Outdoor World的科隆分店是体验式销售的完美例子。这个庞大的商店有一个可供潜水和划独木舟的池... 详细信息

为了让购物更有乐趣,零售商们现在越来越倾向于把商店的各个环节都仔细地加以研究,以改进商品展示和销售的方式。体验式销售Glbbetrotter Outdoor World的科隆分店是体验式销售的完美例子。这个庞大的商店有一个可供潜水和划独木舟的池子,还有一个冰室和一个潮湿的房间以便让顾客在虚拟的环境下体验商品。

关键词：零售商顾客购物品牌商品时尚方式体验商店主要元素

The Effects of Wet Radome on a Short Millimetre-Wave Link in Singapore

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The Effects of Wet Radome on a Short Millimetre-Wave Link in...

Mesenchymal stromal cell-derived small extracellular vesicles modulate macrophage polarization and enhance angio-osteogenesis to promote bone healing

2000 International Conference on Communication Technology(WCC2000·ICCT2000)

作者： Gang Liu J.T.Ong Emily Choo C.G.teo School of Electrical and Electronic Engineering Nanyang Technological University Nanyang Avenue Singapore 639798

＜正＞A short line-of-sight link has been set up at the Nanyang Technological University（NTU） in Singapore to monitor the effect of rain on microwave link performance at *** results suggest that the rain attenuations derived from the measured received levels are much greater than those computed using the ITU-R *** studies at the School of EEE,using rain drop-size-distribution data collected at NTU,indicate that although the rain specific attenuations are higher,they are not as high as the measured value assuming that rain attenuation was the main attenuation *** effects of water on the antenna radome is a possible cause of the higher attenuation *** were conducted to evaluate the effects of water on the antenna radome. These results suggest that significant losses could be introduced at higher microwave band like 38 GHz. Two techniques,called Correlation and Equiprobability method,were developed to separate the attenuation due to rain along the path and that due to water on the antenna *** relationship between wet radome loss and rainfall rate in true rain events is also shown in the paper for the 38 GHz radio link.

关键词： wireless communication rain attenuation wet radome loss

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Genes & Diseases 2022年第4期9卷 841-844页

作者： Shang Jiunn Chuah Chee Weng Yong Kristeen Ye Wen teo Jacob Ren Jie Chew Yi Ann Cheow Shipin Zhang Raymond Chung Wen Wong Asher Ah Tong Lim Sai Kiang Lim Wei Seong Toh Faculty of Dentistry National University of Singapore119085Singapore Institute of Molecular and Cell Biology Agency for ScienceTechnology and Research138648Singapore Department of Orthopaedic Surgery Yong Loo Lin School of MedicineNational University of Singapore119288Singapore Department of Biomedical Engineering Faculty of EngineeringNational University of Singapore117583Singapore Tissue Engineering Program Life Sciences InstituteNational University of Singapore117456Singapore Integrative Sciences and Engineering Program NUS Graduate SchoolNational University of Singapore119077Singapore

Mesenchymal stem/stromal cells(MSCs)have demonstrated therapeutic efficacy for bone regeneration in animal and clinical *** MSCs were initially thought to differentiate to various cell types to replace the injured/diseased tissue,it is now accepted that these cells secrete factors to promote tissue repair.1 Among these factors,small extracellular vesicles(sEVs)of size 50–200 nm,which include the exosomes,have been identified as the principal agent mediating the wide-ranging therapeutic efficacy of MSCs.2 Several studies have also reported the therapeutic effects of MSC-sEVs to enhance bone repair in animal models,as recently reviewed.3 However,the cellular processes and mechanisms mediated by MSC-sEVs in bone regeneration remain to be fully elucidated.

关键词： healing clinical macrophage

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是时候活出自我了(英文)