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兰州大学学报（自然科学版） 2003年第1期39卷 47-53页

作者： MAQing-lin LEUNGPo-lau YANAi-xia HUZhi-de CollegeofChemistryandChemicalEngineering LanzhouUniversityLanzhou730000China DepartmentofPhysicsandMaterialsScience CityUniversityofHongKongKowlooHongKong

EDXRF spectromerty was applied to provenance studies of Neolitic Age(from 6000 BCto 2000 BC)pottery sherds excavated from Gansu Province in north-west China。Major and trace components analysis of te pottery specimen was carried out,and the artificial neural networks has been used to classift the trace com-ponent of these pottery。The results shown that pottery exchange had been existed during 3000 BC in ancient Gansu Province,China。

关键词：新石器时代陶片分类研究甘肃能量色散x荧光光谱人工神经网络产地分析

A Grid Middleware for Distributed Java Computing with MPI Binding and Process Migration Supports

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Journal of Computer Science & Technology 2003年第4期18卷 505-514页

作者：陈琳王卓立 Francis C.M.lau Department of Computer Science and Information Systems The University of Hong Kong P.R. China

"Grid" computing has emerged as an important new research field. With years of efforts, grid researchers have successfully developed grid technologies including security solutions,resource management protocols, information query protocols, and data management services. However, as the ultimate goal of grid computing is to design an infrastructure which supports dynamic,cross-organizational resource sharing, there is a need of solutions for efficient and transparent task re-scheduling in the *** this research, a new grid middleware is proposed, called G-JavaMPI. This middleware adds the parallel computing capability of Java to the grid with the support of a Grid-enabled message passing interface (MPI) for inter-process communication between Java processes executed at different grid points. A special feature of the proposed G-JavaMPI is the support of Java process migration with post-migration message redirection. With these supports, it is possible to migrate executing Java process from site to site for continuous computation, if some site is scheduled to be turned down for system reconfiguration. Moreover, the proposed G-JavaMPI middleware is very portable since it requires no modification of underlying OS, Java virtual machine, and MPI package. Preliminary performance tests have been conducted. The proposed mechanisms have shown good migration efficiency in a simulated grid environment.

关键词： grid middleware MPI Java process migration

Conceptual framework of applying mass valuation in Hong Kong urban renewal compensation scheme

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Journal of Harbin Institute of Technology(New Series) 2004年第5期11卷 537-540页

作者： lau Chi-hong Milton Dept. of Building and Real Estate Faculty of Construction and Land Use Hong Kong Polytechnic University Hong KongChina

In most urban redevelopment projects that take place in Hong Kong, the Urban Renewal Authority (URA) will offer compensation to an owner-occupier based on the market value of the property. The basis of market value assessment is defined as a seven-year-old flat in a comparable quality building, situated in a similar locality in terms of characteristics and accessibility, and located at the middle floor with average orientation. However, little was done in exploring the application and the integration of mass valuation technique in the compulsory acquisition valuation area. This paper endeavors to illustrate the prospects of using mass valuation techniques to value high-rise and strata-title dilapidated buildings by adopting a standardization statistical method to derive resumption estimates.

关键词：城市改建质量评估业主参与破烂建筑物

Novel liver vein deprivation technique that promotes increased residual liver volume(with video):A case report

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World Journal of Clinical Cases 2022年第31期10卷 11579-11584页

作者： Gang Wu Ji-Peng Jiang Dong-Hui Cheng Chong Yang Dong-Xu Liao Yu-Bo Liao Wan-Yee lau Yu Zhang Department of Hepatobiliary Surgery Sichuan Provincial People’s HospitalUniversity of Electronic Science and Technology of ChinaChengdu 610072Sichuan ProvinceChina Organ Transplantation Center Sichuan Provincial People’s HospitalUniversity of Electronic Science and Technology of ChinaChengdu 610072Sichuan ProvinceChina Faculty of Medicine The Chinese University of Hong KongPrince of Wales HospitalHongkong 999077China

BACKGROUND Inadequate volume of future liver remnant(FLR)is a major challenge for hepatobiliary surgeons treating large or multiple liver *** an alternative to associating liver partition and portal vein ligation(ALPPS)for staged hepatectomy and liver venous deprivation(LVD)using stage 1 interventional radiology for vascular embolization combined with stage 2 open liver resection have been *** SUMMARY A novel modified LVD technique was performed in a patient with pancreatic neuroendocrine tumor with liver metastases by using stage 1 laparoscopic ligation of the right hepatic vein,right posterior portal vein,and short hepatic veins combined with local excision of three liver metastases in the left *** operation was followed three days later by interventional radiology to embolize an anomalous right anterior portal vein to complete LVD.A stage 2 laparoscopic right hemihepatectomy and pancreaticosplenectomy were then carried *** The minimally invasive technique promoted a rapid increase,comparable to ALPPS,in volume of the FLR after the stage 1 operation to allow the laparoscopic stage 2 resection to be performed.

关键词： Laparoscopic Liver venous deprivation Future liver remnant Case report

Point-of-care ultrasound for critically-ill patients: A mini-review of key diagnostic features and protocols

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World Journal of Critical Care Medicine 2022年第2期11卷 70-84页

作者： Yie Hui lau Kay Choong See Department of Anaesthesiology Intensive Care and Pain MedicineTan Tock Seng HospitalSingapore 308433Singapore Division of Respiratory&Critical Care Medicine National University HospitalSingapore 119074Singapore

Point-of-care ultrasonography(POCUS)for managing critically ill patients is increasingly performed by intensivists or emergency *** of needs surveys among intensivists reveal emphasis on basic cardiac,lung and abdominal ultrasound,which are the commonest POCUS modalities in the intensive care *** therefore aim to describe the key diagnostic features of basic cardiac,lung and abdominal ultrasound as practised by intensivists or emergency physicians in terms of accuracy(sensitivity,specificity),clinical utility and *** also aim to explore POCUS protocols that integrate basic cardiac,lung and abdominal ultrasound,and highlight areas for future research.

关键词： Critical care Echocardiography Point-of-care testing Sensitivity and specificity Ultrasonography

The innate immune receptor NLRP12 maintains intestinal homeostasis by regulating microbiome diversity

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Cellular & Molecular Immunology 2018年第3期15卷 193-195页

作者： Jenny Moi-Fong lau Yvonne Dombrowski Centre for Experimental Medicine Wellcome-Wolfson Institute for Experimental MedicineQueen’s University BelfastBelfastBT97BLUK

Inflammatory bowel disease(IBD)is on the rise in the western world.1 The dynamic interplay between genetic susceptibility,the gut microbiome and host inflammatory reactions underlying IBD are still *** light onto these complex interactions in IBD,Chen et al.2 identified a key role for the negative immune regulator NLRP12 in shaping the composition of the gut microbiome and maintaining intestinal *** finding,published in the most recent issue of Nature Immunology,2 can advance the development of much needed microbiome-based therapies for IBD patients.

关键词： homeostasis Immunology maintain

Risk of hepatocellular carcinoma after hepatitis C virus cure

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World Journal of Gastroenterology 2022年第1期28卷 96-107页

作者： Maria Alejandra Luna-Cuadros Hao-Wei Chen Hira Hanif Mukarram Jamat Ali Muzammil Muhammad Khan Daryl Tan-Yeung lau Liver Center Division of Gastroenterology and Hepatology Beth Israel Deaconess Medical CenterHarvard Medical SchoolBostonMA 02215United States

Hepatitis C virus(HCV)is a significant cause of hepatocellular carcinoma(HCC).The direct-acting antivirals marked a new era of HCV therapy and are associated with greater than 95%cure *** treatment of chronic hepatitis C greatly reduces the risk of HCC.A proportion of patients,especially those with pre-existing cirrhosis,remain at risk for HCC despite sustained virologic response(SVR).Diabetes mellitus,hepatic steatosis,alcohol consumption and lack of fibrosis regression are associated with risks of HCC after HCV *** modalities such as aspartate aminotransferase to platelet ratio index and fibrosis-4 index and transient elastography have been used to monitor hepatic *** recently,various fibrosis scores have been combined with clinical parameters and other novel biomarkers to predict risks of HCC for patients who achieved *** models still need to be validated and standardized prior to applying to routine clinical care.

关键词： Hepatitis C virus cure Hepatocellular carcinoma Hepatocellular carcinoma risk models Fibrosis markers Transient elastography

Advances in antithrombin therapy for ST-elevation myocardial infarction

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Chinese Medical Journal 2003年第11期116卷 1760-1763页

作者： Wai-hong Chen Chu-Pak lau Department of Medicine Queen Mary Hospital Hong Kong ChinaDepartment of Medicine Queen Mary Hospital Hong Kong China

Thrombin is a pivotal molecule in acute myocardial infarction ( Ml) because of its extensive procoagulant and prothrombotic actions. Antithrombin therapy is an important component of the pharmacotherapy for acute Ml. The standard agent used in clinical practice, unfractionated heparin (UFH), is associated with the disadvantages of variable anticoagulant effect, inability to inhibit clot-bound thrombin, neutralization by platelet factor 4, and the propensity to cause thrombocytopenic complications. Novel thrombin inhibitors have been developed to overcome these disadvantages. Although possessing the property of inhibiting both fluid-phase and clot-bound thrombin, the direct thrombin inhibitor hirudin has been shown to give marginal benefits over UFH as adjunct to fibrinolysis in ST-elevation Ml. Bivalirudin, another direct thrombin inhibitor, is able to reduce reinfarction in patients treated with streptokinase and is a new anticoagulant treatment option in this setting. The pharmacokinetic characteristics of better availability, longer half-life, and dose-independent clearance together with the ability of inhibiting both thrombin generation and activity make the low-molecular-weight heparins (LMWHs) an attractive alternative to UFH. The favorable benefit/risk profile of the LMWHs as adjunct to different generations of fibrinolytic agents is setting the stage for larger clinical trials to confirm their role as the antithrombin agent of choice for STEMI.

关键词： thrombin antithrombotic therapy myocardial infarction

The roles of atypical protein kinase Cs(aPKCs) in the nervous system: targets for neuroregeneration?

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Neural Regeneration Research 2020年第8期15卷 1475-1476页

作者： Dennis Dik-Long Chau Kwok-Fai lau School of Life Sciences The Chinese University of Hong Kong

The protein kinase C(PKC)family:PKC family is a subgroup of the AGC serine-threonine kinases that consists of 10 distinct members in mammals(Spitaler and Cantrell,2004).They all contain a C-terminal catalytic domain that is connected to the N-terminal regulatory *** are subdivided into three classes according to their structures and *** classical/conventional PKC isoforms possess tandem C1 domains that bind to their well-known activators diacylglycerol and phorbol esters and also contain a C2 domain that mediates the binding of Ca^2+-sensitive anionic phospholipids.

关键词： domains. subgroup system

Robust and Efficient Data Transmission over Noisy Communication Channels Using Stacked and Denoising Autoencoders

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China Communications 2019年第8期16卷 82-92页

作者： Faisal Nadeem Khan Alan Pak Tao lau Department of Electrical Engineering The Hong Kong Polytechnic University

We study the effects of quantization and additive white Gaussian noise(AWGN) in transmitting latent representations of images over a noisy communication channel. The latent representations are obtained using autoencoders(AEs). We analyze image reconstruction and classification performance for different channel noise powers, latent vector sizes, and number of quantization bits used for the latent variables as well as AEs’ parameters. The results show that the digital transmission of latent representations using conventional AEs alone is extremely vulnerable to channel noise and quantization effects. We then propose a combination of basic AE and a denoising autoencoder(DAE) to denoise the corrupted latent vectors at the receiver. This approach demonstrates robustness against channel noise and quantization effects and enables a significant improvement in image reconstruction and classification performance particularly in adverse scenarios with high noise powers and significant quantization effects.

关键词： communication channels data compression deep learning autoencoders denoising autoencoders