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Neutron star cooling and GW170817 constraint within quark-meson coupling models

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Chinese Physics C 2021年第2期45卷 531-547页

作者： Odilon Lourenço César H.Lenzi mariana dutra Tobias Frederico M.Bhuyan Rodrigo Negreiros César V.Flores Guilherme Grams Débora P.Menezes Departamento de Física Instituto Tecnológico de AeronáuticaDCTA12228-900São Josédos CamposSPBrazil Department of Physics Faculty of ScienceUniversity of MalayaKuala Lumpur 50603Malaysia Atomic Molecular and Optical Research Group Advanced Institute of Materials ScienceTon Duc Thang UniversityHo Chi Minh CityVietnam Faculty of Applied Sciences Ton Duc Thang UniversityHo Chi Minh CityVietnam Instituto de Física Universidade Federal Fluminense 20420NiteróiRJBrazil Centro de Ciências Exatas Naturais e TecnológicasUEMASULRua Godofredo Viana 1300Centro CEP:65901-480ImperatrizMaranhãoBrazil Departamento de Física Universidade Federal de Santa CatarinaFlorianópolisSCCP 476CEP 88.040-900Brazil Univ.Lyon Univ.Claude Bernard Lyon 1CNRS/IN2P3IP2I LyonUMR 5822F-69622VilleurbanneFrance

In the present work,we used five different versions of the quark-meson coupling(QMC)model to compute astrophysical quantities related to the GW170817 event and the neutron star cooling *** of the models are based on the original bag potential structure and three versions consider a harmonic oscillator potential to confine *** bag-like models also incorporate the pasta phase used to describe the inner crust of neutron *** a simple method studied in the present work,we show that the pasta phase does not play a significant ***,the QMC model that satisfies the GW170817 constraints with the lowest slope of the symmetry energy exhibits a cooling profile compatible with observational data.

关键词： equation of state compact star cooling in stars quark-meson coupling models tidal deformability neutron star merger

Neutron star cooling and GW170817 constraint within quark-meson coupling models

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Chinese Physics C 2021年第2期45卷 535-551页

作者： Odilon Louren?o César H.Lenzi mariana dutra Tobias Frederico M.Bhuyan Rodrigo Negreiros César V.Flores Guilherme Grams Débora P.Menezes Departamento de Física Instituto Tecnológico de Aeronáutica DCTA Department of Physics Faculty of Science University of Malaya Atomic Molecular and Optical Research Group Advanced Institute of Materials Science Ton Duc Thang University Faculty of Applied Sciences Ton Duc Thang University Instituto de Física Universidade Federal Fluminense 20420 Centro de Ciências Exatas Naturais e Tecnológicas UEMASUL Departamento de Física Universidade Federal de Santa Catarina FlorianópolisSC Univ.Lyon Univ.Claude Bernard Lyon 1

In the present work, we used five different versions of the quark-meson coupling(QMC) model to compute astrophysical quantities related to the GW170817 event and the neutron star cooling process. Two of the models are based on the original bag potential structure and three versions consider a harmonic oscillator potential to confine quarks. The bag-like models also incorporate the pasta phase used to describe the inner crust of neutron stars. With a simple method studied in the present work, we show that the pasta phase does not play a significant role. Moreover, the QMC model that satisfies the GW170817 constraints with the lowest slope of the symmetry energy exhibits a cooling profile compatible with observational data.

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美国关于妊娠期间使用呼吸道合胞病毒疫苗预防婴儿呼吸道合胞病毒相关下呼吸道疾病的建议

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中国疫苗和免疫 2024年第3期30卷 377-382页

作者：刘斯宇(编译) 王富珍(审校) FLEMING-dutra KE JONES JM ROPER LE 传染病溯源预警与智能决策全国重点实验室中国疾病预防控制中心北京102206 中国疾病预防控制中心免疫规划中心北京100050 不详

呼吸道合胞病毒(Respiratory syncytial virus,RSV)是导致美国婴儿住院的主要原因。尼塞韦单抗已被推荐用于预防婴儿RSV相关下呼吸道感染(Lower respiratory tract infection,LRTI)。2023年8月,美国食品药品监督管理局(Food and Drug Administration,FDA)批准将单剂量RSVpreF疫苗用于妊娠32-36周孕妇,以预防<6月龄婴儿发生RSV相关LRTI。自2021年10月起,美国免疫实践咨询委员会(Advisory Committee on Immunization Practices,ACIP)RSV疫苗母婴工作组审查了RSV流行病学和RSV母婴预防产品(包括RSVpreF疫苗)在安全性、保护效果和潜在经济影响方面的证据。2023年9月22日,ACIP和疾病控制与预防中心(Centers for Disease Control and Prevention,CDC)推荐采用季节性接种方式(在美国大陆大部分地区为9月至次年1月)为妊娠32-36周孕妇接种RSVpreF疫苗,以预防<6月龄婴儿发生RSV相关LRTI。孕妇在妊娠期间接种RSVpreF疫苗或者为婴儿使用尼塞韦单抗都是预防婴儿发生RSV相关LRTI的推荐方法,但大多数婴儿不需要同时采用两种方法。所有婴儿应通过上述某种产品获得保护,以预防RSV相关LRTI。

关键词：呼吸道合胞病毒下呼吸道疾病呼吸道合胞病毒疫苗预防接种妊娠期婴儿

A closer look at cannabimimetic terpenes, polyphenols, and flavonoids: a promising road forward

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Neural Regeneration Research 2021年第7期16卷 1433-1435页

作者： Juliana Cavalli Rafael Cypriano dutra Laboratory of Autoimmunity and Immunopharmacology Department of Health SciencesCenter of AraranguáFederal University of Santa CatarinaAraranguáSCBrazil Post-Graduate Program of Neuroscience Center of Biological SciencesFederal University of Santa CatarinaFlorianópolisSCBrazil

Despite the current interest in the potential medical use of Cannabis, it is worth remembering that cannabis is not a new drug, with both a nonmedical and medical history supporting its *** history advanced in scientific strength and importance worldwide when Professor Raphael Mechoulam and colleagues initiated their pioneering discoveries in *** first, Mechoulam et al.(1972) achieved the complete synthesis of the pure compounds from hashish(including △1-tetrahydrocannabinol and other neutral cannabinoids such as cannabigerol, cannabichromene, and cannabicyclol), and established their molecular structures.

关键词： closer initiated neutral

Pramipexole, a dopamine D3/D2 receptor-preferring agonist, attenuates reserpine-induced fibromyalgia-like model in mice

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Neural Regeneration Research 2022年第2期17卷 450-458页

作者： Carlos Pereira Martins Rodrigo Sebben Paes Gabriela Mantovani Baldasso Eduarda Gomes Ferrarini Rahisa Scussel Rubya Pereira Zaccaron Ricardo Andrez Machado-de-Avila Paulo Cesar Lock Silveira Rafael Cypriano dutra Laboratory of Autoimmunity and Immunopharmacology Department of Health SciencesCampus AraranguaUniversidade Federal de Santa CatarinaAraranguáSCBrazil Post-Graduate Program of Neuroscience Center of Biological SciencesUniversidade Federal de Santa CatarinaFlorianópolisSCBrazil Laboratory of Experimental Physiopathology Program of Postgraduate in Science of HealthUniversidade do Extremo Sul CatarinenseCriciumaSCBrazil

Fibromyalgia(FM) is a complex pathology described as persistent hyperalgesia including somatic and mood dysfunctions, depression and anxiety. Although the etiology of FM is still unknown, a significant decrease in biogenic amines is a common characteristic in its pathogenesis. Here, our main objective was to investigate the role of dopamine D3/D2 receptor during the reserpine-induced pain in mice. Our results showed that pramipexole(PPX) – a dopaminergic D3/D2 receptor agonist – inhibited mechanical allodynia and thermal sensitivity induced by reserpine. Relevantly, PPX treatment decreased immobility time and increased the number of grooming in the forced swimming test and splash test, respectively. Animals that received PPX remained longer in the open arms than the reserpine group using elevated plusmaze apparatus. The repeated PPX administration, given daily for 4 days, significantly blocked the mechanical and thermal allodynia during FM model, similarly to pregabalin, although it failed to affect the reserpine-induced thermal nociception. Reserpine administration induced significant downregulation of dopamine concentration in the central nervous system, and repeated treatment with PPX restored dopamine levels in the frontal cortex and spinal cord tissues. Moreover, PPX treatment inhibited oxidants production such as DCFH(2′,7′-dichlorodihydrofluorescein) and nitrite, also decreased oxidative damage(carbonyl), and upregulated the activity of superoxide dismutase in the spinal cord. Together, our findings demonstrated the ability of dopamine D3/D2 receptor-preferring agonist in reducing pain and mood dysfunction allied to FM in mice. All experimental protocols were approved by the Universidade Federal de Santa Catarina(UFSC) Ethics Committee(approval No. 2572210218) on May 10, 2018.

关键词： dopamine dopaminergic system fibromyalgia hyperalgesia pain pramipexole reserpine

Role of the floodplain lakes in the methylmercury distribution and exchanges with the Amazon River,Brazil

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Journal of Environmental Sciences 2018年第6期30卷 24-40页

作者： Poliana dutra Maia Laurence Maurice Emmanuel Tessier David Amouroux Daniel Cossa Patricia Moreira-Turcq Henri Etcheber Universidade de Brasilia-Faculdade UnB Planaltina Area Universitaria n. 1-Vila Nossa Senhora de Fatima Planaltina 73300-000 Brasilia DF Brazil Geosciences Environnement Toulouse (GET) Observatoire Midi Pyrenees Universite de Toulouse CNRS IRD14 Avenue Edouard Belin F-32400 Toulouse France CNRS/Univ Pau & Pays Adour Institut des Sciences Analytiques et de Physico-Chimie pour l'Environnement et les Materiaux UMR5254 F-64000 Pau Prance Universite Grenoble Alpes CP 40700 F-38058 Grenoble Cedex 9 France EPOC UMR 5805 Universite de Bordeaux I Av. des Facultes F-33405 Talence France

Seasonal variability of dissolved and particulate methylmercury（F-MeHg, P-MeHg） concentrations was studied in the waters of the Amazon River and its associated Curuai floodplain during hydrological year 2005–2006, to understand the MeHg exchanges between these aquatic systems. In the oxic white water lakes, with neutral pH, high F-MeHg and P-MeHg concentrations were measured during the rising water stage（0.70 ± 0.37 pmol/L, n = 26） and flood peak（14.19 ± 9.32 pmol/g, n = 7） respectively, when the Amazon River water discharge into the lakes was at its maximum. The lowest mean values were reported during the dry season（0.18 ± 0.07 pmol/L F-MeHg, n = 10 and 1.35 ± 1.24 pmol/g P-MeHg, n = 8）, when water and suspended sediments were outflowing from the lakes into the River. In these lakes,the MeHg concentrations were associated to the aluminium and organic carbon/nitrogen changes. In the black water lakes, with acidic pH and reducing conditions, elevated MeHg concentrations were recorded（0.58 ± 0.32 pmol/L F-MeHg, n = 16 and 19.82 ± 15.13 pmol/g PMeHg, n = 6）, and correlated with the organic carbon and manganese concentrations. Elevated values of MeHg partition coefficient（4.87 〈 Kd〈 5.08 log（L/kg） indicate that MeHg is mainly transported associated with the particulate phase. The P-MeHg enrichment detected in all lakes suggests autochthonous MeHg inputs from the sediments into the water column. The MeHg mass balance showed that the Curuai floodplain is not the source of P-MeHg for the Amazon River.

关键词： Methylmercury Water Sediment Amazon River Floodplain lakes

Acute heart failure as an adverse event of tumor necrosis factor inhibitor therapy in inflammatory bowel disease:A review of the literature

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World Journal of Cardiology 2023年第5期15卷 217-228页

作者： Thais Gagno Grillo Caroline Ferreira da Silva Mazeto Pupo Silveira Ana Elisa Valencise Quaglio Renata de Medeiros dutra Julio Pinheiro Baima Silmeia Garcia Zanati Bazan Ligia Yukie Sassaki Department of Internal Medicine Medical SchoolSão Paulo State UniversityBotucatuBotucatu 18618686Brazil Department of Biophysics and Pharmacology Institute of BiosciencesSão Paulo State UniversityBotucatuBotucatu 18618689Brazil

Tumor necrosis factor inhibitors(anti-TNFs)are widely used therapies for the treatment of inflammatory bowel diseases(IBD);however,their administration is not *** failure(HF),although rare,is a potential adverse event related to administration of these ***,the exact mechanism of development of HF remains ***αis found in both healthy and damaged *** effects are concentration-and receptor-dependent,promoting either cardio-protection or cardiomyocyte *** rat models with TNFαreceptor knockout showed increased survival rates,less reactive oxygen species formation,and improved diastolic left ventricle ***,clinical trials employing anti-TNF therapy to treat HF had disappointing results,suggesting abolishment of the cardioprotective properties of TNFα,making cardiomyocytes susceptible to apoptosis and ***,patients with IBD who have risk factors should be screened for HF before initiating anti-TNF *** review aims to discuss adverse events associated with the administration of anti-TNF therapy,with a focus on HF,and propose some approaches to avoid cardiac adverse events in patients with IBD.

关键词： Tumor necrosis factor inhibitors Inflammatory bowel disease Heart failure Adverse event TNFαreceptor

Morphological and molecular diversity of arbuscular mycorrhizal fungi in revegetated iron-mining site has the same magnitude of adjacent pristine ecosystems

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Journal of Environmental Sciences 2018年第5期30卷 330-343页

作者： Caroline Krug Vieira Matheus Nicoletti Marascalchi Arthur Vinicius Rodrigues Rafael dutra de Armas Sidney Luiz Stürmer Universidade Regional de Blumenau(FURB) Programa de Pos-Graduacao em Engenharia Ambiental89030-903 BlumenauSCBrazil Universidade Regional de Blumenau(FURB) Departamento de Ciencias Naturais(DCN)89030-903 BlumenauSCBrazil Uniuersidade Regional de Blumenau(FURB) Programaa de Pos-Graduacao em Engenharia Florestal89030-903 BlumenauSCBrazil Centro Universitario-Catolica de Santa Catarina 89203-005 JoinvilleSCBrazil

Arbuscular mycorrhizal fungi（AMF） are important during revegetation of mining sites, but few studies compared AMF community in revegetated sites with pristine adjacent ecosystems. The aim of this study was to assess AMF species richness in a revegetated iron-mining site and adjacent ecosystems and to relate AMF occurrence to soil chemical parameters. Soil samples were collected in dry and rainy seasons in a revegetated iron-mining site（RA） and compared with pristine ecosystems of forest（FL）, canga（NG）,and Cerrado（CE）. AMF species were identified by spore morphology from field and trap cultures and by LSU r DNA sequencing using Illumina. A total of 62 AMF species were recovered, pertaining to 18 genera and nine families of Glomeromycota. The largest number of species and families were detected in RA, and Acaulospora mellea and Glomus sp1 were the most frequent species. Species belonging to Glomeraceae and Acaulosporaceae accounted for 42%–48% of total species richness. Total number of spores and mycorrhizal inoculum potential tended to be higher in the dry than in the rainy season, except in RA. Sequences of uncultured Glomerales were dominant in all sites and seasons and five species were detected exclusively by DNA-based identification. Redundancy analysis evidenced soil p H,organic matter, aluminum, and iron as main factors influencing AMF presence. In conclusion, revegetation of the iron-mining site seems to be effective in maintaining a diverse AMF community and different approaches are complementary to reveal AMF species, despite the larger number of species being identified by traditional identification of field spores.

关键词： Community structure Glomeromycota Illumina LSU rDNA Spore morphology Taxonomic distinctness index

Postoperative pain due to an occult spinal infection:A case report

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World Journal of Clinical Cases 2021年第15期9卷 3637-3643页

作者： Michiel Frederik Vande Kerckhove Vincent Fiere Thais dutra Vieira Sami Bahroun Marc Szadkowski Henrid'Astorg Centre Orthopédique Santy Hopital PrivéJean MermozRamsay-Générale de SantéLyonFrance

BACKGROUND A high degree of vigilance is warranted for a spinal infection,particularly in a patient who has undergone an invasive procedure such as a spinal *** average delay in diagnosing a spinal infection is 2-4 *** our patient,the diagnosis of a spinal infection was delayed by 1.5 *** SUMMARY A 60-year-old male patient with a 1-year history of right-sided lumbar radicular pain failed conservative *** weeks to prior to surgery he received a spinal injection,which was followed by increasing lumbar radicular pain,weight loss and *** went unnoticed and surgery took place with right-sided L4-L5 combined microdiscectomy and foraminotomy via a posterior *** day after surgery,the patient developed left-sided lumbar radicular *** cultures grew Staphylococcus aureus(***).Magnetic resonance imaging showed inflammatory aberrations,revealing septic arthritis of the left-sided L4/L5 facet joint as the probable *** surgery took place and *** was isolated from bacteriological *** patient received postoperative antibiotic treatment,which completely eradicated the *** The development of postoperative lower back pain and/or lumbar radicular pain can be a sign of a spinal infection.A thorough clinical and laboratory work-up is essential in the preoperative evaluation of patients with spinal pain.

关键词： Arthritis Septic Lumbar region Disc herniated Spinal injections Case report