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Characterization of two Achromobacter xylosoxidans isolates from patients with pertussis-like symptoms

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Asian Pacific journal of Tropical Medicine 2015年第6期8卷 465-468页

作者： Fiorella Orellana-Peralta Michelle jacinto maria j.pons Cláudia Gomes Carlos Bada Isabel Reyes juana del Valle Mendoza joaquim Ruiz Facultad de Ciencias de la Salud.Universidad Peruana de Ciencias Aplicadas-LiPC LimaPeru ISGlobal Barcelona Ctr.Int.Health Res.(CRESIB)Hospital Clinic-Universitat de Barcelona Hospital de Emergencias Pediatricas.Lima Peru Instituto de Investigacion Nutrirional LimaPeru

Objective:To characterize two Achromobaeter xylosoxidans recovered from 2 patients diagnosed with pertussis during a Bordetella pertussis surveillance ***:Nasopharyngeal swabs from 2 children under 1 year of age with clinical suspicion of pertussis were analyzed by culture and ***:Two Achromobaeter xylosoxidans A8,closely related to Bordetella *** recovered from 2 patients diagnosed of pertussis,both carrying the ptxA gene and IS418 the pertussis toxin encoding ***,antibiotic susceptibility was evaluated by disk-diffusion method and by ***:Although more detailed studies are needed,the present data highlight the possibility that Achromobaeter *** related Bordetella pertussis microorganisms and not covered under the vaccine umbrella,might also result in cases of whooping *** further surveillance is necessary to determine the extension and relevance of their pathogenic role in order to discriminate their real public health implication.

关键词： Achromobacter xylosoxidans Bordetella pertussis

An atypical case of disseminated cutaneous leishmaniasis due to Leishmania peruviana in the valleys of Ancash-Peru

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Asian Pacific journal of Tropical Medicine 2017年第11期10卷 1101-1103页

作者： Diego Espinoza-Morales Aldo Lucchetti Rodríguez Wilmer Silva-Caso Luis Suarez-Ognio María j.pons juana del Valle Mendoza School of Medicine Health Sciences FacultyUniversidad Peruana de Ciencias AplicadasAv.San Marcos cdra Cedros de Villa LimaPeru 2Infectology ServicieHospital Arzobispo LoayzaAv.Alfonso Ugarte 848Cercado de LimaLimaPeru Research Center and Innovation of the Health Sciences Faculty Universidad Peruana de Ciencias AplicadasAv.San Marcos cdra 2 ChorrillosLimaPeru

We present an atypical case of disseminated cutaneous leishmaniasis in the Sihuas district, located in the Andean valleys of Ancash-Peru. A 62-year-old man with no particular medical history presented multiple lesions located on the inferior abdomen, lumbar region and the right anterior thigh. Histological analysis found leishmanial amastigotes in the lesion sample, the Montenegro reaction was positive for Leishmania spp, and the polymerase chain reaction was positive for Leishmania peruviana. In conclusion, the atypical presentation of this disease may be related to the presence of an uncommon parasite strain or host immune deficiencies. The molecular identification of the etiology for disseminated leishmaniasis, will allow a better understanding of the presentation and proper treatment,as well as associated risk factors.

关键词： Leishmaniasis Leishmania peruviana PCR Peru

Arboviruses emerging in Peru: Need for early detection of febrile syndrome during El Ni?o episodes

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Asian Pacific journal of Tropical Medicine 2016年第8期9卷 796-797页

作者： Derek Tantaléan-Yépez josé Sánchez-Carbonel Gabriela Ulloa-Urizar Diego Espinoza- Morales Miguel Angel Aguilar-Luis Wilmer Silva-Caso María j.pons juana del Valle- Mendoza School of Medicine Health Sciences Faculty Universidad Peruana de Ciencias Aplicadas (UPC) Research Center and Innovation of the Health Sciences Faculty Universidad Peruana de Ciencias Aplicadas (UPC)

The presence of El Ni?o Southern Oscillation(ENSO)implies the presence of fluctuating rains in coastal areas and these changes influence the occurrence of febrile syndromes *** Peru,Aedes aegypti is the vector responsible for various viruses such as the dengue,Zika,chikungunya,which is distributed in 18 Peruvian *** viruses cause similar clinical characteristics in the host and for this reason rapid,sensitive and specific diagnostic tests are needed so that the patient can receive timely treatment.

关键词： Febrile syndrome Dengue Chikungunya Zika

Energy Conversion Mechanics for Photon Emission per Non-Local Hidden-Variable Theory

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journal of Modern Physics 2016年第10期7卷 1049-1067页

作者： Dirk j. pons Arion D. pons Aiden j. pons Department of Mechanical Engineering University of Canterbury Christchurch New Zealand University of Cambridge Cambridge UK Rangiora New Life School Rangiora New Zealand

Problem-Energy conversion processes in optical phenomena are incompletely explained by wave theory or quantum mechanics. There is a need for ontologically rich explanations at the level of individual particles. Purpose: This paper reports on the application of a non-local hidden-variable solution called the Cordus theory to this problem. The method is directed to the systematic development of a conceptual framework of proposed causal mechanisms. Findings: It has long been known that the bonding commitments of the electron affect its energy behaviour but the mechanisms for this have been elusive. We show how the degree of bonding constraint on the electron determines how it processes excess energy. A key concept is that the span and frequency of the electron are inversely proportional. This explains why energy changes cause positional distress for the electron. Natural explanations are given for multiple emission phenomena: Absorbance;Saturation;Beer-Lambert law;Colour;Quantum energy states;Directional emission;Photoelectric effect;Emission of polarised photons from crystals;Refraction effects;Reflection;Transparency;Birefringence;Cherenkov radiation;Bremsstrahlung and Synchrotron radiation;Phase change at reflection;Force impulse at reflection and radiation pressure;Simulated emission (Laser). Originality: The paper elucidates a mechanism for how the electron responds to combinations of bonding constraint and pumped energy. The crucial insight is that the electron size and position(s) are coupled attributes of its frequency and energy, where the coupling is achieved via physical substructures. The theory is able to provide a logically coherent explanation for a wide variety of energy conversion phenomena.

关键词： Photon Light Electron Emission Cordus Conjecture Physical Interpretation

Entropy at the Level of Individual Particles: Analysis of Maxwell’s Agent with a Hidden-Variable Theory

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journal of Modern Physics 2016年第10期7卷 1277-1295页

Problem: Maxwell’s Agent (MA) is a thought experiment about whether the second Law is violated at smaller scales. This is a complex problem because the scale dependencies are unclear for perfect gas assumptions, quantum coherence, thermalisation, and contextual measurement. Purpose: The MA is explored from a non-local hidden-variable (NLHV) perspective. Approach: The Cordus theory, a specific NLHV solution, was applied at macroscopic to fundamental scales. Physical realism requires the Agent be included in the analysis. Findings: The primary function is sorting, i.e. a one-time separation of species by some attribute. The thermodynamic MA situation is merely a special case for reducing disorder (entropy). A one-time extraction of energy is possible. This requires input energy, hence the device only has thermodynamic leverage and is not a perpetual motion device. Inefficiencies arise from thermalisation causing short mean free path of Brownian motion, perfect gases having minimal interaction with the gate, ambiguity about spatial location arising from quantum superposition, contextual measurement interfering with the particle velocity, and bremsstrahlung hysteresis losses occurring when the Agent operates. Implications: Entropy is a group property at the bulk level, not a characteristic of the individual particle, and can be reversed at an energy cost at the particle level. Originality: The explanation spans multiple levels from macroscopic down to fundamental, which is unusual. Achieving an explanation from the NLHV sector is novel. The theory accommodates superposition, irreversibility, entropy, contextual measurement, coherence-discord transition, and Brownian motion.

关键词： Entropy Irreversibility Ratchet Demon Thermodynamics Contextual Measurement

Differences of silicon photodiode spectral reflectance among the same batch

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Optoelectronics Letters 2008年第5期4卷 347-350页

作者： A.L.Muoz Zurita j.Campos Acosta A.pons Aglio A.Shcherbakov Department of Optics National Institute for AstrophysicsOptics and ElectronicsA.P.51 y 216Puebla72000México. CSIC-Institute for Applied Physics C.P.28006MadridSpain.

Photodiode＇s reflectance plays an important role regarding the relation between responsivity and the incident flux. In this work we analyze how the spectral reflectance changes among photodiodes from the same manufacturer and batch and how the reflectance of three standard photodiodes has drifted during six years. The results show that the reflectance changes from diode to diode within the same batch and also show that the reflectance ofphotodiodes changes on time. This ageing is spectraUy dependent.

关键词：硅发光二极管光谱反射率响应度

Asymmetrical Genesis by Remanufacture of Antielectrons

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journal of Modern Physics 2014年第17期5卷 1980-1994页

作者： Dirk j. pons Arion D. pons Aiden j. pons Department of Mechanical Engineering University of Canterbury Christchurch New Zealand University of Canterbury Christchurch New Zealand aiden@pons.ws

Problem: The asymmetrical genesis problem concerns why the universe should have an abundance of matter over antimatter. Purpose: This paper shows how the baryogenesis and leptogenesis asymmetries may both be resolved. Approach: Design methods were used to develop a conceptual mechanics for the remanufacturing processes that transform particles in the decay processes. This was based on the structures for the photon, electron, antielectron, proton and antineutrino as previously identified as logical necessities for the beta decay process, and represented as a non-local hidden-variable design with discrete fields. Findings: The solution is given in terms of a mechanics that defines the transformation of discrete field structures in particles. The genesis problem is shown to be solvable. The mechanics describes pair production of an electron and antielectron from two initial photons, and subsequent remanufacture of the antielectron into a proton. It is predicted that two antineutrinos would be emitted, which are testable and falsifiable. The theory identifies that the role of the antineutrinos is to remove the antimatter handed field structures. The original electron and proton may bond to form a simple hydrogen atom, or combine via electron capture to form a neutron and hence heavier nuclides. The subsequent preponderance of the matter pathways in the genesis production sequence is also addressed and is explained as domain warfare between the matter and antimatter species. Originality: The concept of remanufacture of antielectrons into protons, with emission of antineutrinos, is novel. Extensions of the theory explain the nuclides. Consequently the theory explains from pair production up to nuclear structure, which is also original.

关键词： Asymmetry Antimatter Annihilation Chirality Proton Decay Non-Local Hidden-Variable NLHV

A Physical Explanation for Particle Spin

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journal of Modern Physics 2019年第7期10卷 835-860页

作者： Dirk j. pons Arion D. pons Aiden j. pons Department of Mechanical Engineering University of Canterbury Christchurch New Zealand University of Cambridge Cambridge UK University of Canterbury Christchurch New Zealand

CONTEXT The spin of a particle is physically manifest in multiple phenomena. For quantum mechanics (QM), spin is an intrinsic property of a point particle, but an ontological explanation is lacking. In this paper we propose a physical explanation for spin at the sub-particle level, using a non-local hidden-variable (NLHV) theory. APPROACH Mechanisms for spin were inferred from the Cordus NLHV theory, specifically from theorised structures at the sub-particle level. RESULTS Physical geometry of the particle can explain spin phenomena: polarisation, Pauli exclusion principle (Einstein-Podolsky-Rosen paradox), excited states, and selective spin of neutrino species. A quantitative derivation is provided for electron spin g-factor g = 2, and a qualitative explanation for the anomalous component. IMPLICATIONS NLHV theory offers a candidate route to new physics at the sub-particle level. This also implies philosophically that physical realism may apply to physics at the deeper level below QM. ORIGINALITY The electron g-factor has been derived using sub-particle structures in NLHV theory, without using quantum theory. This is significant as the g-factor is otherwise considered uniquely predicted by QM. Explanations are provided for spin phenomena in terms of physical sub-structures to the particle.

关键词： Non-Local Hidden-Variable Theory Cordus g Factor Fundamental Physics Spin

A Physical Basis for Entanglement in a Non-Local Hidden Variable Theory

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journal of Modern Physics 2017年第8期8卷 1257-1274页

Problem: Superposition and entanglement are coherent effects, which can be quantified by quantum mechanics (QM), but lack descriptive explanations. They are typically analysed with inequality methods, and the results favour QM and reject physical realism and hidden-variable solutions. In particular, Colbeck & Renner (2011) showed that no extension of quantum theory can exist with better predictive power than quantum mechanics itself. Purpose: The purpose here is to critically evaluate from a conceptual and philosophical perspective the ontological underpinnings of the inequality approach. The current work is speculative in nature as it is based on a conjectured non-local hidden-variable (NLHV) design for particles, and does not yet have a mathematical formalism. Nonetheless this is worth attempting for the philosophical questions it poses about the nature of reality, and the pointers it gives to possible future directions in fundamental physics. Findings: The premises of the C & R proof (that particles are points, that locality exists, that quantum theory is correct) are inconsistent, hence invalidate its conclusion. We also show that superposition and entanglement may be qualitatively explained if particles were to have the internal structure proposed by the Cordus NLHV theory. Originality: The ability to explain superposition and entanglement conceptually in terms of physical realism is relevant because it rebuts the claim that it is impossible that such a hidden-variable theory could exist. This is significant because previously it has been believed that these phenomena are explainable by QM only.

关键词： Non-Local Superposition Entanglement Coherence