Is glucose-6-phosphate dehydrogenase deficiency more prevalent in Carrion's disease endemic areas in Latin America?

作     者：Fernando Mazulis Claudia Weilg Carlos Alva-Urcia Maria J.Pons Juana del Valle Mendoza 

作者机构：School of MedicineResearch Center of the Health Sciences FacultyUniversidad Peruana de Ciencias Aplicadas(UPC) 

出 版 物：《Asian Pacific Journal of Tropical Medicine》 (亚太热带医药杂志（英文版）)

年 卷 期：2015年第8卷第12期

页      面：1045-1046页

核心收录：

学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

基　　金：CONCYTEC/ FONDECYT(grant number:CG05-2013-FONDECYT) 

主　　题：Glucose-6-phosphate dehydrogenase G6PD Bartonella 

摘      要：Glucose-6-phosphate dehydrogenase(G6PD) is a cytoplasmic enzyme with an important function in cell oxidative damage *** have a predisposition towards oxidized environments due to their lack of mitochondria,giving G6 PD a major role in its stability.G6 PD deficiency(G6PDd) is the most common enzyme deficiency in humans:it affects approximately 400 million individuals *** overall G6 PDd allele frequency across malaria endemic countries is estimated to be 8%.corresponding to approximately 220 million males and 133 million ***,there are no reports on the prevalence of G6 PDd in Andean communities where bartonellosis is prevalent.