检索结果-南通市图书馆

In Vitro Propagation, Isolation and Expression Studies of Suaeda edulis Genes Involved in the Osmoprotectants Biosynthesis

引用

Phyton-International Journal of Experimental Botany 2020年第3期89卷 715-726页

作者： Gloria Viviana Cerrillo-Rojas mariana Tiscareno-Andrade Ana Erika Ochoa-Alfaro Eugenio Perez-Molphe Balch Ruth Elena Soria-Guerra Jose Francisco Morales-dominguez Departamento de Quimica Universidad Autonoma de AguascalientesCentro de Ciencias BasicasCiudad UniversitariaAguascalientes20131Mexico Facultad de Quimica Universidad Autonoma de San Luis PotosiZona UniversitariaSan Luis Potosi78210Mexico

Halophytes are an excellent choice for the study of genes conferring salt tolerance to salt-sensitive plants and,they are suitable for reclamation and remediation of saline *** develop an in vitro plant propagation protocol and studies of genes involved with GB and Pro biosynthesis in Suaeda *** buds were used as explants and cultured in different treatments on Murashige and Skoog(MS)medium supplemented with different concentrations and combinations of plant growth *** highest number of multiple shoots was on MS medium containing 1 mg/L Benzyladenine(BA)and/or 2 g/L activated carbon with 5.5±06 shoots per *** identification and expression analysis of genes involved in glycine betaine(GB)biosynthesis were S-adenosyl-methionine synthetase(SAMS),choline monooxygenase(CMO)and betaine alde-hyde dehydrogenase(BADH),and for proline(Pro)was pyrroline 5-carboxylate synthetase(P5CS).These sequences shared 90–95%of identity with others plant homologous in public *** amino acids sequence analysis showed that all these peptides contain some of the conserved motifs of those kinds of *** qRT-PCR analysis revealed a higher expression of SeBADH,SeCMO,and,SeP5CS genes in the roots and leaves from plants collected in the field in contrast with from in vitro ***,the expression level of SeSAMS was higher only in the leaves of plants collected in the field when com-pared to those cultivated in vitro.

关键词： Axillary buds halophyte proline glycine betaine salt-resistant

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Framework of treating Alzheimer’s dementia

引用

Brain Science Advances 2019年第2期5卷 82-93页

作者： Yuan-Han Yang Rajka Liscic Jacqueline dominguez Department of Neurology Kaohsiung Municipal Ta-Tung HospitalTaiwanChina Department of Neurology Kaohsiung Medical University HospitalKaohsiungTaiwanChina Neuroscience Research Center Kaohsiung Medical UniversityKaohsiung CityTaiwanChina Department of Neurology Johannes Kepler University LinzAustria Institute for Neurosciences St.Luke's Medical CenterQuezon CityPhilippines

Current treatment paradigm in Alzheimer’s disease(AD)involves multiple approaches combining pharmacological and nonpharmacological intervention to mitigate the clinical symptoms,slow the progressive loss of cognitive and functional abilities,or modify the disease *** far,beyond anti-cholinesterase inhibitors(ACh EIs),donepezil,rivastigmine,galantamine,and antagonist of N-methyl-D-aspartic acid(NMDA)receptor,there are no newly approved medicines to treat *** pharmacological treatment,the personal characteristic and the intra-individual therapeutic evaluations to examine various cognitive domains,behavioral and psychological problems,and global function should be considered when choosing any of ACh *** use of optimal dosage referring to the expected clinical outcomes and currently reported deficits from patient with AD has become an important issue in clinical *** and maintaining a strong therapeutic alliance to physician,patient,and caregiver is crucial and central to the comprehensive care in AD.

关键词： donepezil rivastigmine galantamine memantine Alzheimer’s disease

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

针刺治疗女性膀胱过动症的病例系列研究

针刺治疗女性膀胱过动症的病例系列研究

引用

作者： Nuria dominguez Palicio 北京中医药大学

学位级别：硕士

背景:膀胱过动症(OAB)是以一种以尿急为主要特征的临床综合征。OAB常伴有尿频及夜尿,可伴或不伴有急迫性尿失禁,但不存在尿路感染或其他明显的病理因素引起的类似症状。可以发生在任何年龄段,以中老年女性多见。以人群为基础的研究发现,... 详细信息

背景:膀胱过动症(OAB)是以一种以尿急为主要特征的临床综合征。OAB常伴有尿频及夜尿,可伴或不伴有急迫性尿失禁,但不存在尿路感染或其他明显的病理因素引起的类似症状。可以发生在任何年龄段,以中老年女性多见。以人群为基础的研究发现,0AB是一种非常普遍的疾病,成年女性发病率为大约16.5%。该疾病同其他主要的慢性病一样,每年给全球造成了沉重的经济负担。药物疗法由于副作用风险较高,疗效欠佳,患者依从性差及长期成本高等原因,仍未必是最佳选择。0AB严重影响着患者的生活质量,但并未引起人们足够的重视和得到较好的解决。非药物疗法因其对0AB具有较好的疗效而逐渐获得广泛的关注,例如西医学中的神经刺激术以及中医学中的针灸疗法。神经刺激术是指一些调节膀胱功能和促进储尿的技术。骶神经刺激术(SNS),作为一种常用的神经刺激手段,曾被用于0AB的循证医学治疗。然而,SNS技术要求较高,难度大,且可能给患者造成进一步的侵入性伤害。因此,一项可行性更高,侵入性较小的技术,经皮胫神经刺激术(PTNS)应运而生。PTNS源于中医针灸,类似于电针刺激三阴交穴,于20世纪80年代首次被提出。尽管PTNS将治疗的侵入性降至最低且患者花费较少,但却是耗时的。因此,在西方医学中,新的植入技术正在发展并初露头角。针刺凭借其安全、有效、简便易行、价格低廉等优势已广泛地应用于0AB的治疗,尤其是在中国,但其证据仍然不足。最近,一项高质量的临床随机对照试验表明,与假针组相比,患有压力性尿失禁的妇女在接受电针刺激腰骶区治疗之后,漏尿症状减轻。动物实验证实,电针三阴交穴可以抑制过度活动的膀胱。针刺三阴交穴治疗0AB临床较为方便,但是以三阴交穴为主穴治疗0AB的临床证据仍然缺乏。此外,针刺治疗是一种兼具多样性与个性化的干预措施,其疗效包括针刺效应、针灸理论指导下的特殊的非针刺效应、以及非针刺疗法所独有的普遍效应。同时,针刺治疗应当基于病人的具体状况和中医理论指导,如辨证论治。因此,我们有必要进行一些真实世界的针刺研究以评价针刺治疗0AB的有效性和安全性。目的:本研究的目的在于观察针刺治疗膀胱过动症的疗效,以寻求安全、有效、便捷的针刺治疗OAB的方案。方法:试验设计及场所:本研究为病例系列研究。于2018年1月4日至2018年6月期间,在西班牙Gabinet Diagnosi Girona诊所开展。受试者:试验期间从诊断和治疗中心妇科门诊共招募12例受试者,遵循纳入和排除标准,随后获得受试者知情同意。受试者最少接受4个疗程的治疗。干预方法:针灸治疗的腧穴处方以三阴交、关元、足三里、百会、神庭、合谷和太冲穴为主穴,运用平补平泻手法获得适宜的针感,并根据受试者的中医证型加减穴位。针刺治疗期间,根据受试者具体状况,分别于受试者腰骶部及腹部运用拔罐及烤灯疗法。结局指标:主要结局指标是排尿次数和排尿冲动次数。0ABSS评分(Homma)包扩4个关于OAB症状的问题:日间尿频,夜尿频率,尿急和尿失禁(UII)。四个分数的评分总和在0至15分之间。次要结局指标是与0AB超过24小时有关的夜间醒来次数、最大膀胱容量(注册时)和超声评估0AB的体征。尿失禁患者的ICIQ-SF问卷及3天排尿日记。此外,我们还考虑了超过24小时受试者使用的护垫的数量、生活质量量表(Q0L)问卷、不良事件和受试者退出。结果:12例受试者中有10例受试者的主要结局指标得到了改善,即减少了排尿总次数及排尿冲动的发作次数。12例受试者的0ABSS均发生变化(时间范围,在基线和治疗结束后)。这种变化直接显示出受试者0AB症状的主观改善。同时我们还发现,在4例具有尿急和尿失禁(UUI)症状的受试者中,3例治疗后24小时护垫使用数量减少,其由于0AB所致的夜间醒来次数(24小时内)亦减少。膀胱容量(mL)及超声评估0AB征象,仅2例受试者得到改善。其余受试者变化不显著。在仅有的4例具有尿急和尿失禁的受试者中,在其基线和治疗结束时均记录了尿失禁ICIQ-SF精简问卷和3天排尿日记。针刺治疗后,尿急和尿失禁症状均有改善。治疗前后,所有受试者均进行了生活质量量表(QOL)问卷评估。结果显示,所有12例受试者均认为治疗后生活质量有所提高。针刺时的不良事件仅表现为2例受试者感受到的轻微疼痛,1例受试者的皮下血肿,并未引起任何医疗纠纷。1例受试者因开始治疗后出现血小板减少而退出治疗。结论:本病例系列研究初步显示,针刺治疗女性膀胱过动症安全、有效、简便易行。中医从整体和综合的角度,辨证论治,将过度活跃的膀胱视为一个综合症的一部分进行治疗。尽管有其局限性,但本病例系列研究表明,除三阴交穴外,采用更多穴位联合治疗膀胱过动症可能疗效更佳,这也许有助于目前西医常用的经皮胫神经刺激术(PTNS)等技术的改良。本研究结果显示了针刺对女性OAB具有一定的疗效

关键词：针刺膀胱过动症三阴交穴病例系列研究

来源：

同方学位论文库评论

在线全文

同方学位论文库

学校读者我要写书评

暂无评论

Measuring Vertical and Horizontal Intra-Industry Trade:the Case of Mexico and China

Measuring Vertical and Horizontal Intra-Industry Trade:the C...

引用

作者： Natalia Primo dominguez 南京理工大学

学位级别：硕士

The purpose of this study is *** and analyze the extent of vertical and horizontal intra-industry trade between Mexico and China in seven sectors over a five-year period,from 2012 to 2016,using disaggregated trade data at the SITC three digit level;and to identify in what sectors IIT is rmainly ***,this paper aims to disentangle trade into:inter-industry trade,horizontal intra-industry trade,low quality vertical ITT（low ITTV）and high quality vertical ITT（high-ITTV）.One of the main findings is that there is relatively low bilateral intra-industry trade between Mexico and ***,the results showed that vertical ⅡT took predominance over horizontal IIT in all *** further disentangling vertical IIT,the results demonstrated that it was high-ITTV that prevailed over *** this type of trade,China is mainly exporting low quality goods to Mexico.

关键词：中国对外贸易墨西哥

来源：

同方学位论文库评论

在线全文

同方学位论文库

学校读者我要写书评

暂无评论

Construction and Characterization of an Ultrasonic Array Using Different Backing Materials to Evaluate Crosstalk

引用

材料科学与工程（中英文B版） 2013年第8期3卷 493-497页

作者： Israel Sanchez dominguez Pedro Acevedo Contla Polytechnic University of Madrid School of lndustrial Engineering Madrid 28001 Spain National Autonomous University of Mexico Institute of Research in Applied Mathematics and Systems Mexico City 04510Mexico

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

SENP7 overexpression protects cancer cells from oxygen and glucose deprivation and associates with poor prognosis in colon cancer

引用

Genes & Diseases 2022年第6期9卷 1419-1422页

作者： Francisco Gallardo-Chamizo Nieves Lara-Urena Juan F.Correa-Vazquez Jose C.Reyes Benoit R.Gauthier Mario Garcia-dominguez Cell Dynamics and Signaling Department CABIMERCSICUniversidad de Sevilla-Universidad Pablo de Olavide-Junta de AndaluciaSeville 41092Spain Genome Biology Department CABIMERCSIC-Universidad de Sevilla-Universidad Pablo de Olavide-Junta de AndaluciaSeville 41092Spain Cell Therapy and Regeneration Department CABIMERCSIC-Universidad de Sevilla-Universidad Pablo de Olavide-Junta de AndaluciaSeville 41092Spain Centro de Investigacion Biomedica en Red de Diabetes y Enfermedades Metabo´licas Asociadas(CIBERDEM) Madrid 28029Spain

To the Editor,Constricted oxygen and glucose supplies are common conditions that healthy cells following a stress such an ischemic insult as well as cancer cells within a solid tumor need to overcome in order to *** conditions are a serious challenge for cells,which accurately measure the impact to make a life or death *** cancer cells,aberrant gene expression and/or protein regulation,frequently linked to appearing mutations,may confer selective advantages to survive under these adverse *** the past years,cumulative evidence indicates that protein modification by covalent attachment of the Small Ubiquitin-like MOdifier(SUMO)plays a role in cell survival after oxygen and glucose deprivation(OGD).

关键词： cancer deprivation colon

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Determinants of mechanical restraint in an acute psychiatric care unit

引用

World Journal of Psychiatry 2021年第10期11卷 854-863页

作者： Khadija El-Abidi Antonio R Moreno-Poyato Alba Toll Privat David Corcoles Martinez Rosa Acena-dominguez Victor Perez-Sola Anna Mane Department of Psychiatry Institut de Neuropsiquiatria i AddiccionsParc de Salut MarBarcelona 08003Spain Public Health Mental and Maternal and Child HealthSchool of NursingFaculty of Medicine and Health SciencesUniversity of BarcelonaBarcelona 08907Spain Biomedical Research Institut Hospital del Mar d'Investigacions MediquesBarcelona 08003Spain Biomedical Research Center for Biomedical Research in Mental Health NetworkBarcelona 08003Spain Department of Psychiatry Institut de Neuropsiquiatria i AddiccionsCentre FòrumBarcelona 08019Spain

BACKGROUND Despite numerous attempts to reduce the use of mechanical restraint(MR),this technique continues to be widely applied in many acute psychiatric care *** order to reduce MR,a better understanding of the variables associated with its use and duration in different clinical environments is *** To determine the proportion of patients subjected to MR and the duration thereof in two acute care psychiatric units;and to identify the variables associated with the use and duration of *** Descriptive study of all patients admitted to the acute psychiatric units at the Parc de Salut Mar(Barcelona,Spain)in the year *** number and percentage of patients subjected to MR,as well as the duration of each episode were *** following data were also registered:sociodemographic characteristics,psychiatric diagnosis,and presence of cultural and/or language *** analyses were performed to assess determinants of MR and its *** Of the 464 patients,119(25.6%)required MR,with a median of 16.4 h per *** factors-a diagnosis of psychotic disorder[Odds ratios(OR)=0.22;95%CI:0.06-0.62;P=0.005]and the presence of a language barrier(OR=2.13;95%CI:1.2-3.7;P=0.007)-were associated with a significantly higher risk of *** sex was associated with a longer duration of MR(B=-19.03;95%CI:-38.06-0.008;P=0.05).CONCLUSION The presence of a language barrier and a psychotic disorder diagnosis are associated with a significantly higher risk of ***,male sex is associated with a longer duration of *** restraint protocols that include the required tools are necessary to ultimately limit the use of mechanical restraint.

关键词： Mechanical restraint Prolonged restraint Determining factors Psychiatric acute unit

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Adalimumab in ulcerative colitis: Two cases of mucosal healing and clinical response at two years

引用

World Journal of Gastroenterology 2009年第30期15卷 3814-3816页

作者： Manuel Barreiro-de Acosta Aurelio Lorenzo Juan Enrique dominguez-Muoz Department of Gastroenterology University Hospital of Santiago de CompostelaC/Choupanas/nE-15706-Santiago de CompostelaSpain

Infliximab (IFX) is currently the only biologic therapy used in the treatment of moderate-to-severe ulcerative colitis (UC). In the years to come, more biologic therapies will have a role in the management of moderate-to-severe UC. We report on two patients with steroid-dependent UC who, due to adverse reactions to IFX, have been under therapy with adalimumab for two years. Both patients received concomitant immunosuppressive treatment. Long term clinical remission and mucosal healing are described.

关键词： Adalimumab Ulcerative colitis Mucosalhealing Maintenance treatment

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Adsorption of NO on Activated Carbon： Equilibrium and Energetic Interactions

引用

材料科学与工程（中英文版） 2010年第4期4卷 41-46页

作者： Rosario Hernandez-Huesca Gelacio Aguilar-Armenta Gerardo dominguez Centro de lnvestigacion de la Facultad de Ciencias Quimicas Benemerita Universidad Autonoma de Puebla Blvd. 14 sur y Av. San Claudio Ciudad Universitaria Puebla C.P. 72570 Pue. Mexico

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Formation of the Hole Centers in Zinc-Oxide Nanoparticles During Mechanical Processing of ZnO ＋ xMnO2

引用

材料科学与工程（中英文版） 2010年第1期4卷 11-15页

作者： Mykola Kakazey Marina Vlasova Martha dominguez-Patifio CIICAp Universidad Autonoma del Estado de Morelos Cuernavaca 62209 Morelos Mexico FCQI Universidad Autonoma del Estado de Morelos Cuernavaca 62209 Morelos Mexico

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：