检索结果-南通市图书馆

Aortic valve stenosis provides complementary information to bleeding risk scores in non-valvular atrial fibrillation patients initiating anticoagulation

引用

Journal of Geriatric Cardiology 2020年第3期17卷 141-148,I0005-I0007页

作者： Gines Elvira-Ruiz Cesar Caro-Martinez Pedro JoseFlores-Blanco Juan JoseCerezo-Manchado helena Albendin-Iglesias Alejandro Lova-Navarro Francisco Arregui-Montoya Francisca maria Munoz-Franco Natalia Garcia-Iniesta Arcadio Garcia-Alberola JoseLuis Bailen-Lorenzo Domingo Andres Pascual-Figal Sergio Manzano-Fernández Department of Cardiology University Hospital Virgen de la ArrixacaMurciaSpain Instituto Murciano de Investigación en Biomedicina(IMIB) MurciaSpain Department of Cardiology University Hospital Morales MeseguerMurciaSpain Department of Hematology University Hospital Virgen de la ArrixacaMurciaSpain Department of Internal Medicine University Hospital Virgen de la ArrixacaMurciaSpain School of Medicine University of MurciaMurciaSpain Department of Cardiology Hospital Vega BajaAlicanteSpain

Background The identification of modifiable bleeding risk factors may be of *** aim is to evaluate if aortic stenosis(AS)provides additional information to bleeding risk scores for predicting major bleeding(MB)in non-valvular atrial fibrillation(AF).Methods We designed a retrospective multi-center study including 2880 consecutive non-valvular AF patients initiating oral anticoagulation between January 2013 and December *** was defined as moderate or severe according to European echocardiography guidelines ***,ATRIA and ORBIT scores were used to evaluate the bleeding *** was defined according to the International Society on Thrombosis and Haemostasia criteria and registered at 18 months of *** 168(5.8%)patients had *** with AS had higher risk for MB compared to those without AS(HR=2.13,95%CI:1.40-3.23,P<0.001).Patients without AS and low-intermediate bleeding risk(0 points)showed the lowest MB rate,whereas the MB rate observed among patients with AS and high bleeding risk(2 points)was the highest *** and reclassification analyses showed that AS provided additional information to bleeding risk scores for predicting MB at 18 months of *** In this population,AS was associated with an increased risk for MB at midterm *** three scoring systems showed a moderate discriminatory ability for ***,the addition of AS was associated with a significant improvement in their predictive *** suggest that the presence of this valvulopathy should be taken into account for bleeding risk assessment.

关键词： Anticoagulants Aortic stenosis Atrial fibrillation Major bleeding Valvular disease

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

In Vitro Evaluation of Gamma Irradiation on a Gel Formulation of Cratylia Mollis: Rheological Proporties and Microbiological Control

引用

Journal of Cosmetics, Dermatological Sciences and Applications 2012年第2期2卷 45-50页

作者： maria helena Madruga Lima-Ribeiro Ralph Santos-Oliveira Mauricelia Firmino De Santana Terezinha De Jesus Andreoli Pinto Irene Satiko Kikuchi Cheila Goncalves Mothe Luana Cassandra Breitenbach Barroso Coelho maria Tereza Dos Santos Correia Ana maria Dos Anjos Carneiro-Leao Laboratory of Immunopathology Keizo Asami(LIKA) Federal University of PernambucoRecifeBrazil Nuclear Engineering Institute Laboratory of NanoradiopharmaceuticalsRio de JaneiroBrazil Biochemistry Department Federal University of PernambucoRecifeBrazil Pharmacy Department University of Sao PauloSao PauloBrazil School of Chemistry Federal University of Rio de JaneiroRio de JaneiroBrazil Departament of Morphology and Animal Physiology Federal Rural University of PernambucoRecifeBrazil

Lectin Cramoll-1,4, obtained from Cratylia mollis seeds (beans camaratu) was structurally characterized, biologically and pharmacologically, but its use as a biopharmaceutical is not well documented. The objective of this study is to propose a biopharmaceutical formulation lectin Cramoll-1,4, test their hemagglutinating properties in vitro as well as the use of gamma radiation as a continuous process of decontamination formulation. It was made of the extraction and purification Cramoll-1,4, was developed a gel formulation using Carbopol? as a vehicle, at concentrations of 50, 100, 200, 300 and 600 μg was irradiated with 60Co gamma rays in a dose of 7.549 kGy·h–1. The proposed formulation at a concentration of 300 μg produced an increase in the hemagglutinating units Cramoll-1,4 due to the synergistic effect caused by gamma radiation. Considering the diverse use of lectins, specific molecular and structural factors, as well as changes resulting from its formulation, concentration, irradiation and route of administration is of utmost importance to continue the studies in vitro, for subsequent application in vivo to characterize the physiological and molecular processes involved in the response and cellular effects.

关键词： Gamma Radiation Natural Products Hemagglutinating Activity Cramoll-1 4

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Flavonoid Contents and Antioxidant Activity in Fruit,Vegetables and Other Types of Food

引用

Agricultural Sciences 2015年第4期6卷 426-435页

作者： Juliana Cristina Pereira Calado Paula Adriana Albertao Erica Aparecida de Oliveira Mario Henrique Sisto Letra Alexandra Christine helena Frankland Sawaya maria Cristina Marcucci Post-Graduated School in Pharmacy Anhanguera University of Sao Paulo(UNIAN-SP)Sao PauloBrazil Department of Plant Biology and Pharmacy Course Institute of BiologyUniversidade Estadual de CampinasUNICAMPCampinasBrazil

Flavonoids are a class of natural polyphenolic compounds which cannot be synthesized by humans. These substances possess a series of biological properties, acting on biological systems as antioxidants. The purpose of this study was to analyze the properties of certain foods, determining the total flavonoids as well as their antioxidant activity and fat concentration. We evaluated several foods purchased at the local market, with respect to its antioxidant activity, using two experimental models, the discoloration of DPPH˙ radical and ABTS-. Some foods such as pitanga showed antioxidant activity. The lipid content of fatty foods like aaí, cacao and cupuaú was determined. Other foods, including pitanga, aaí, cacao and cupuaú, were evaluated for flavonoid content and antioxidant activity using multivariate statistical analysis (PCA) as a statistical tool to evaluate the correlation between these two parameters. As samples with ED50 up to 500 μg/mL show promising antioxidant activity, several Brazilian fruit and vegetables could be consumed to this end, with a good correlation between flavonoid content and antioxidant activity in most samples. The daily dose of different types of food for antioxidant activity has been calculated based on these results.

关键词： Amount of Lipids Antioxidant Activity Chemometric Analysis Fat Content Flavonoids Food Fruit Vegetables

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Coffee and Caffeine Intake among Students of the Brazilian Northeast

引用

Food and Nutrition Sciences 2016年第1期7卷 30-36页

作者： Andreza Gomes Penafort Isabella Barbosa Pereira Carneiro Antônio Augusto Ferreira Carioca maria Olganê Dantas Sabry Francisco José Maia Pinto helena Alves de Carvalho Sampaio University of Fortaleza Fortaleza Brazil State University of Ceara Fortaleza Brazil

The purpose of this study was to evaluate the pattern of intake of coffee and caffeine-containing food among students in a post-secondary institution in northeastern Brazil. We interviewed 498 students. Among these students, 72.3% (n = 360) reported to consume coffee, with a higher pre- valence among women (68.3%) and students aged between 18 and 25 years (82.8%). The student’s residence itself was the top location for taking coffee (90.6%) and the most widely used method of preparation was brewing coffee using a cloth filter (82.5%). The average intake of coffee was 199.0 ± 230.6 ml/day, with a frequency of 1.6 ± 1.4 times a day and concentration between 4% - 12%. Coffee was the main source of caffeine and the average daily intake of 147.3 ± 141.2 mg of caffeine was low. The data showed that the intake of coffee and caffeine does not represent a risk factor for the population studied. On the other hand, the scarcity of national studies on the subject points to the need of similar research about customer profile and pattern of consumption of coffee and caffeine, especially regarding the preparation technique of coffee, featuring benefits or risks for the development of chronic diseases.

关键词： Coffee Caffeine Chronic Disease

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Stimulation of the P6 Acupuncture Point for Prophylaxis of Nausea and Vomiting in Pregnant Women Submitted to Cesarean Section: A Blinded Clinical Trial

引用

Open Journal of Anesthesiology 2013年第3期3卷 161-164页

作者： Luiza helena Castelo Branco Luciana Cavalcante Lima maria Célia Ferreira Costa Marilia Santos Lira Raquel Queiroz Guerra de Andrade Coelho Tania Cursino de Menezes Couceiro Anne Danielle Soares Eusa maria Belarmino Alcoforado maria Emilia Carvalho Instituto de Medicina Integral Prof. Fernando Figueira (IMIP) Recife Brazil.

In pregnant women subjected to spinal anesthesia for a Cesarean section, episodes of nausea and vomiting are common both during and following surgery. Acupuncture for the prophylaxis and treatment of these complications has been gaining in popularity due to its low cost, simplicity, absence of side effects and confirmed efficacy. This study investigated the efficacy of stimulating the P6 acupoint in conjunction with the use of dexamethasone as prophylaxis for nausea and vomiting in pregnant women submitted to spinal anesthesia for a Cesarean section. The patients (n = 100) were randomly distributed into two groups. In the first group (n = 50), a site located one centimeter laterally from P6 was stimulated. This is not a true acupuncture point (sham acupuncture). In the second group (n = 50), P6 was stimulated. In both groups, 4 mg of dexamethasone were administered intravenously. A questionnaire was used to obtain information on the occurrence of nausea and vomiting during surgery and in the first 12 hours postpartum. The chi-square test and Fisher’s exact test were used to assess differences between the groups. Age and physical status were similar in both groups. The incidence of nausea during surgery was 32% (n = 16) in the control group and 22% (n = 11) in the P6 group (p > 0.05). In the first 12 hours following surgery, nausea occurred in 16% of the women in the control group (n = 6) and in 4% in the P6 group (n = 4) (p = 0.045). The incidence of vomiting in the control group was 12% (n = 6) during surgery and 10% (n = 5) in the postoperative period compared to 8% (n = 4) and 4% (n = 2), respectively, in the P6 group (p > 0.05). Although these differences were not statistically significant with the exception of the incidence of nausea in the first 12 hours postpartum, a reduction occurred in the incidence of all the outcomes evaluated in the P6 group.

关键词： Obstetric Surgery Cesarean Section Complications Nausea Vomiting Prophylaxis Acupuncture

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Groove Pancreatitis： A Case Report

引用

Journal of Pharmacy and Pharmacology 2018年第4期6卷 415-419页

作者： Luciana Leony Valente mariama Alves Dantas Fagundes Camila Medrado Pereira Barbosa Helio Miguel de Azevedo Biao Veiga maria helena da Silva Borges Department of Gastroenterology of Hospital Sao Rafael Salvador-Bahia 41253-190 Brazil

We report a case of groove pancreatitis in which clinical and endoscopic findings improved with conservative treatment. Most authors suggest more aggressive management, such as Whipple＇s surgery because of its similar findings to pancreatic carcinoma. Groove pancreatitis is a rare condition that requires more studies to establish diagnostic criteria to better classify the disease＇s stage and direct appropriated therapy for the patient, improving morbidity and survival of this disease.

关键词： Groove pancreatitis pancreatic carcinoma duodenopancreatectomy.

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Clinical use of estimating glomerular filtration rate equ-ations during pregnancy

引用

Health 2011年第1期3卷 32-36页

作者： Luiz Paulo José Marques Regina Rocco maria helena Victor Benedita Calheiros de Novaes Ana Luiza Batista de Carvalho Omar da Rosa Santos 不详

Background: Kidney disease, even when mild, was once considered so major an impediment to successful pregnancy and so dangerous to the mother’s wellbeing. High-risk pregnancy mainly associated to renal impairment may occur in 10-20% of gestations and it is very important that renal function is closely monitored to prevent or minimize maternal and fetal complications. This study was designed to investigate the performance of Cockcroft-Gault CGeq and the simplified MDRDeq equations in healthy pregnant women to assess renal function. Methods: We studied 167 normal ambulatory pregnant women and kidney function was contemporaneously estimated through the CGeq and the simplified MDRDeq and calculated through the creatinine clearance (Ccr). Serum and urinary creatinine were assayed using Jaffé reaction method in the same AutoAnalyser. Results: When we compared calculated and estimated clearences for measurement of kidney function we observed that CGeq overestimated renal function (CGeq = 168.41 ± 38.80 ml/ min/1.73 m2, Ccr = 146.27 ± 30.49 ml/min / 1.73 m2, p < 0.001), MDRDeq underestimated renal function (Ccr = 146.27 ± 30.49 ml/min / 1.73 m2, MDRDeq = 129.15 ± 29.28 ml/min / 1.73m2, p < 0.001). Conclusions: Our results demonstrated that CGeq overestimated, MDRDeq underestimated significantly kidney function during gestation in healthy women and cannot be recommended to assess renal function in obstetric practice. Ccr remains a useful clinical tool in pregnant women until the development of a specific equation that considers the several important maternal renal physiological alterations and provides the measure of GFR the most unbiased and precise as possible.

关键词： Pregnancy Kidney function Glomerular Filtration Rate MDRD equation Cockcroft-Gault equation.

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Cross-sectional study to determine viral hepatitis knowledge in different urban populations in Brazil

引用

World Journal of Hepatology 2018年第11期10卷 867-876页

作者： helena Medina Cruz Jakeline Ribeiro Barbosa Jeová Keny Baima Colares Antonio Henrique Almeida de Moraes Neto maria de Fátima Leal Alencar Francisco Inácio Bastos Jurema Corrêa da Mota Filipe Aníbal Carvalho-Costa Claudia Alexandra Pontes Ivantes Lia Laura Lewis-Ximenez Livia Melo Villar Laboratory of Viral HepatitisOswaldo Cruz Institute Fiocruz Rio de Janeiro 21040360 Brazi Postgraduate Program in Pathology Federal University of Ceará Fortaleza Ceará 60020181 Brazil Postgraduate Program in Medical Sciences University of Fortaleza Ceará 60430160 Brazil Laboratory of Innovations in Therapies Teaching and Bioproducts Oswaldo Cruz Institute Fiocruz Rio de Janeiro 21040360 Brazil Institute of Communication and Scientifc Information and Technology for Health Oswaldo Cruz Foundation Rio de Janeiro 21040900 Brazil Laboratory of Epidemiology and Molecular Systematics Oswaldo Cruz Institute Fiocruz Rio de Janeiro 21040900 Brazil Orientation and Counselling Centre Curitiba Paraná 80810070 Brazil

AIM To evaluate viral hepatitis knowledge among individuals from different resource areas and health conditions to identify possible *** A cross-sectional, descriptive study was carried out among 447 individuals from five distinct populations in Brazil: Southeast Viral Hepatitis Ambulatory(n = 100), South(n = 89) and Northeast(n = 114) Health Center, Southeast(n = 77) and Northeast(n = 67) low resource areas. All individuals answered a questionnaire assessing sociodemographic characteristics and viral hepatitis awareness. The perception was scored based on the average number of correct answers of all participants and categorized as "low"(0-28 correct answers) or "desirable"(29-46 correct answers). Associations between sociodemographic characteristics and perception were also *** A low level of knowledge was observed in individuals from Northeast Health Center, Northeast and Southeast low resource areas while desirable knowledge was observed in individuals from Viral Hepatitis Ambulatory and South Health Center. According to sociodemographic characteristics, desirable scores were more common among those with secondary education(47.1%), those who declared themselves as white(46.3%), and those who lived in houses with three individuals(25.5%). Multivariate analysis showed an association between viral hepatitis perception and type of population. CONCLUSION The results demonstrated high level of knowledge among study participants from health clinics from the Southeast region of Brazil and the importance of education programs in increasing the level of knowledge in low resource areas.

关键词： Viral hepatitis Knowledge Perception Urban population Brazil

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

The Ethics and the Meaning of Life among College Students

引用

International Journal of Clinical Medicine 2018年第4期9卷 221-233页

作者： maria helena de Agrela Goncalves Jardim Geraldo Bezerra da Silva Junior Marcia Lucia Sousa Dias Alves Bruna Raquel Figueira Ornelas de Gouveia Rita Baptista Silva School of Health University of MadeiraFunchalPortugal Visiting Researcher at UNIFOR by Capes/Funcap FortalezaBrazil Health Sciences Center University of FortalezaFortalezaBrazil Hospital of Dr.Nelio Mendonca MadeiraPortugal Abel Salazar Biomedical Sciences Institute University of PortoPortoPortugal 6School of Nursing of Sao Jose de ClunnyFunchalPortugal Nursing Sciences University of PortoPortoPortugal

The concern of the ethics and the meaning of life in young adults became universal and are present in all contexts of human life. Such universality is due to the development of modern rationality, to establish a relationship between the intrinsic theoretical dimensions (scientific) and practical dimensions (ethical), originated that are present in the own array of knowledge. This descriptive cross-sectional study, aims to identify the values of the ethical dimension and meaning of life defended by the college students of the Universities of Madeira, Portugal and Fortaleza, Brazil. The sample consists of 605 University students (Madeira = 225 and Fortaleza = 380), with an average age of 21 years and a standard deviation of 2. We used the questionnaire on values (adapted from the European Values Survey). Most of the young people referred to have a religion (60% wood and 78.4% stronghold), being the most Catholic, however, present in your frequency disinterest and, yet, in Brazil there is a greater diversity of religions. Supporting the intervention of religious institutions in situations of everyday life is accepted mostly by Brazilians, with the exception of politics (35.5%). On the other hand, the university students of the University of Madeira understand that Religious Institutions should only give their opinion on racial discrimination (76.6%). Believe in God (90.8% and 55.1% Stronghold) and Soul (80.3% and 66.4% Stronghold) are beliefs more referred to by college students. These results are intended to contribute in the field of research on ethical values and meaning of life in young people. This study contributes to future comparative research among university students and to developing strategic programs in education and health, increasing the success and excellence in the formation of a full citizenship, preventing the fanaticisms and the social discrimination that today devastate the collective globally.

关键词： Values Ethics Meaning of Life Young Adults College Students Questionnaire on Values (QSV)

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Rice and Bean:Glycemic Index and Glycemic Load of the“Baiao de Dois”

引用

Agricultural Sciences 2014年第9期5卷 770-775页

作者： Tatiana Uchoa Passos helena Alves de Carvalho Sampaio Soraia Pinheiro Machado Arruda maria Luisa Pereira de Melo Jose Wellington de Oliveira Lima Daianne Cristina Rocha Public Health State University of CearaFortalezaBrazil Pharmacology State University of CearaFortalezaBrazil

The “bai?o de dois” is a typical Brazilian dish and a rich combination of rice and beans. This preparation has a high nutritional value but its effect on glycemic response is not yet studied. To determine the glycemic index and glycemic load of foods can help prescribing diets and as a result, improving the treatment and prevention of chronic diseases. This study aimed to access the glycemic index (GI) and glycemic load (GL) of “bai?o de dois”. Following the protocol recommended by the Food and Agriculture Organization, 6 volunteers were recruited to perform blood glucose tests. Each volunteer performed three glucose tolerance tests and a test with “bai?o de dois”. All tests were undertaken in separate weeks. Through the calculation of the areas under each of the curves, it was possible to access the GI of “bai?o de dois” by the average values of six GIs found for each volunteer. It was calculated that the GL of each portion tested and recommended servings per capita. It was found that “bai?o de dois” had low GI (44) and GL (6) at the recommended per capita, but high GL (22) at the portion tested (bigger than the recommended). The “bai?o de dois” do not present a potential risk for developing chronic diseases, but it is recommended consumption to be monitored.

关键词： Glycemic Index Glycemic Load Regional Food Baiao de Dois Chronic Disease

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：