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Kinematics ofmandibular advancement devices(MADs):Why do some MADs move the lower jaw backward duringmouth opening?

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Bio-Design and Manufacturing 2024年第5期7卷 637-650页

作者： Juan A.Cabrera Alex Bataller sergio postigo marcos García Mechanical Engineering Department University of Malaga29071 MalagaSpain

Mandibular advancement devices(MADs)are widely used treatments for obstructive sleep *** function by advancing the lower jaw to open the upper *** increase patient comfort,most patients allow the mouth to be ***,not all systems maintain the lower jaw in a forward position during mouth opening,which results in the production of a retrusion that favors the collapse of the upper ***,the kinematic behavior of the mechanism formed by the mandible-device assembly depends on jaw *** means that,during mouth opening,some devices cause lower jaw protrusion in some patients,but cause its retraction in *** this study,we report the behavior of well-known devices currently on *** do so,we developed a kinematic model of the lower jawdevice *** validated for all devices analyzed using a high-resolution camera *** results show that some of the devices analyzed here did not produce the correct behavior during patient mouth opening.

关键词： Mandibular advancement devices Lower jaw kinematics sleep apnea

plant-available water capacity of soils at a regional scale:Analysis of fixed and dynamic field capacities

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pedosphere 2024年第3期34卷 590-605页

作者： Vinod pHOGAT paul RpETRIE Casandra COLLINs marcos BONADA south Australian Research and Development Institute GPO Box 397Adelaide SA 5001(Australia) school of Agriculture Food and WineWaite Research InstituteUniversity of AdelaideWaite CampusPMB1Glen Osmond SA 5064(Australia) College of science and Engineering Flinders UniversityBedford Park SA 5042(Australia) The University of New south Wales Sydney NSW 2052(Australia) ARC Training Centre for Innovative Wine production University of AdelaidePMB1Glen Osmond SA 5064(Australia)

Estimation of the plant-available water capacity(pAWC)of soils at a regional scale helps in adopting better land use planning,developing suitable irrigation schedules for crops,and optimizing the use of scarce water *** the current study,72 soil profiles were sampled from the Barossa region of south Australia to estimate pedo-transfer functions deduced from easily estimated soil *** functions were then used to estimate the fixed(10 and 33 kpa)and dynamic pressure head(h_(fc))water contents at field capacity(FC)for minimum drainage flux(0.01 and 0.001 cm d^(-1)),which serves as the upper boundary for plant-available water in *** estimated residual water content was corrected for subsoil constraints,especially the exchangeable sodium percentage(Esp).The results showed that the mean values of h_(fc)in sand-dominated light and medium textured soils(i.e.,sand,loamy sand,sandy loam,and loam)varied in a narrow range(15.8-18.2 kpa),whereas those in the clay-dominated heavy textured soils(i.e.,clay loam)showed a wide range(11.3-49.3 kpa).There were large differences in pAWC for dynamic FC(pAWC_(fc))and fixed FC at 10 kpa(pAWC10),33 kpa(pAWC33),and a mix of 10and 33 kpa(pAWC_(10,33))pressure heads depending on soil ***,the difference between pAWC at 10 kpa and h_(fc)(ΔpAWC_(10))was positive,whereas that between 33 kpa and h_(fc)(ΔpAWC_(33))was negative across all ***,the estimation of pAWC assuming a fixed FC at 10 and 33 kpa pressures(i.e.,pAWC_(10,33))for sandy,clay,and silty soils reduced the difference between fixed and dynamic pressure pAWCs toss the *** estimation of pAWC was improved by incorporating the impact of subsoil constraints,such as high Esp,which was more pronounced for clay and silty *** findings demonstrate the inherent inconsistencies between static pressure and flux-based dynamic FC estimations in *** heterogeneity,intra-texture variability,subsoil constraints,and swell

关键词： crop lower limit drained upper limit pedo-transfer function soil hydraulic parameter soil texture

Advancements in autoimmune hepatitis management:perspectives for future guidelines

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World Journal of Hepatology 2024年第2期16卷 135-139页

作者： marcos Mucenic Liver Transplantation Group Santa Casa de Porto AlegrePorto Alegre 90035-070RSBrazil

The first-line treatment for autoimmune hepatitis involves the use of prednisone or prednisolone either as monotherapy or in combination with azathioprine(AZA).Budesonide has shown promise in inducing a complete biochemical response(CBR)with fewer adverse effects and is considered an optional first-line treatment,particularly for patients without cirrhosis;however,it is worth noting that the design of that study favored budesonide.A recent real-life study revealed higher CBR rates with prednisone when equivalent initial doses were *** guidelines recommend mycophenolate mofetil(MMF)for patients who are intolerant to *** is important to mention that the evidence supporting this recommendation is weak,primarily consisting of case ***,MMF has demonstrated superiority to AZA in the context of renal *** comparative studies have shown higher CBR rates,lower therapeutic failure rates,and reduced intolerance in the MMF *** findings may influence future guidelines,potentially leading to a significant modification in the first-line treatment of autoimmune *** recently,the only alternative to corticosteroids was lifelong maintenance treatment with AZA,which comes with notable risks,such as skin cancer and *** trials are essential for a more comprehensive assessment of treatment suspension strategies,whether relying on histological criteria,strict biochemical criteria,or a combination of ***-center studies using chloroquine diphosphate have shown promising results in significantly reducing relapse rates compared to ***,these interesting findings have yet to be replicated by other research ***,second-line drugs,such as tacrolimus,rituximab,and infliximab,should be subjected to controlled trials for further evaluation.

关键词： Autoimmune hepatitis Treatment Immunosuppression Relapse Remission induction

Enhanced entropy generation and heat transfer characteristics of magnetic nano-encapsulated phase change materials in latent heat thermal energy storage systems

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Applied Mathematics and Mechanics(English Edition) 2024年第6期45卷 1051-1070页

作者： p.s.REDDY p.sREEDEVI Department of Mathematics Rajeev Gandhi Memorial College of Engineering and TechnologyNandyal 518501India

The objective of the current study is to investigate the importance of entropy generation and thermal radiation on the patterns of velocity,isentropic lines,and temperature contours within a thermal energy storage device filled with magnetic nanoencapsulated phase change materials(NEpCMs).The versatile finite element method(FEM)is implemented to numerically solve the governing *** effects of various parameters,including the viscosity parameter,ranging from 1 to 3,the thermal conductivity parameter,ranging from 1 to 3,the Rayleigh parameter,ranging from 102 to 3×10^(2),the radiation number,ranging from 0.1 to 0.5,the fusion temperature,ranging from 1.0 to 1.2,the volume fraction of NEpCMs,ranging from 2%to 6%,the stefan number,ranging from 1 to 5,the magnetic number,ranging from 0.1 to 0.5,and the irreversibility parameter,ranging from 0.1 to 0.5,are examined in detail on the temperature contours,isentropic lines,heat capacity ratio,and velocity ***,the heat transfer rates at both the cold and hot walls are analyzed,and the findings are presented *** results indicate that the time taken by the NEpCMs to transition from solid to liquid is prolonged inside the chamber region as the fusion temperatureθf ***,the contours of the heat capacity ratio Cr decrease with the increase in the stefan number ste.

关键词： volume fraction of nano-encapsulated phase change material(NEpCM) radiation stefan number heat capacity ratio entropy generation

ChatGpT and exercise prescription:Human *** or human plus machine?

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Journal of sport and Health science 2024年第5期13卷 661-662页

作者： Timothy Gustavo Cavazzotto Diego Bessa Dantas marcos Roberto Queiroga Department of physical Education Midwestern Parana State UniversityParana 85040-167Brazil postgraduate program in physical Education UEM-UEL State University of LondrinaParana 86057-970Brazil

The power of artificial intelligence(AI)to create stories,music,art,and other creative projects has been demonstrated and criticized over recent decades in media,mainly because of the idea that AI will replace human *** recently,in November 2022,reactions to Chat Generative pre-training Transformer(ChatGpT)release for public use reverberated in news and social media headlines,while its users exceeded100 million in just a few *** is a natural language processing program created by AI non-profit OpenAI Inc.

关键词： prescription replace Human

Efficient slope reliability analysis under soil spatial variability using maximum entropy distribution with fractional moments

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Journal of Rock Mechanics and Geotechnical Engineering 2024年第4期16卷 1140-1152页

作者： Chengxin Feng marcos A.Valdebenito Marcin Chwała Kang Liao Matteo Broggi Michael Beer Institute for Risk and Reliability Leibniz University HannoverCallinstr.34Hannover30167Germany Chair for Reliability Engineering TU Dortmund UniversityLeonhard-Euler-Str.5Dortmund44227Germany Faculty of Civil Engineering Wrocƚaw University of Science and TechnologyWrocƚawPoland Faculty of Geosciences and Environmental Engineering Southwest Jiaotong UniversityChengdu610031China University of Liverpool Institute for Risk and UncertaintyPeach StreetLiverpoolL69 7ZFUnited Kingdom International Joint Research Center for Resilient Infrastructure & International Joint Research Center for Engineering Reliability and stochastic Mechanics Tongji UniversityShanghaiChina

spatial variability of soil properties imposes a challenge for practical analysis and design in geotechnical *** latter is particularly true for slope stability assessment,where the effects of uncertainty are synthesized in the so-called probability of *** probability quantifies the reliability of a slope and its numerical calculation is usually quite involved from a numerical *** view of this issue,this paper proposes an approach for failure probability assessment based on Latinized partially stratified sampling and maximum entropy distribution with fractional *** spatial variability of geotechnical properties is represented by means of random fields and the Karhunen-Loève ***,failure probabilities are estimated employing maximum entropy distribution with fractional *** application of the proposed approach is examined with two examples:a case study of an undrained slope and a case study of a slope with cross-correlated random fields of strength parameters under a drained *** results show that the proposed approach has excellent accuracy and high efficiency,and it can be applied straightforwardly to similar geotechnical engineering problems.

关键词： slope Random field Reliability analysis Maximum entropy distribution Latinized partial stratified sampling

Complexed amino acid minerals ***-glycinate chelated minerals:Impact on the performance of old laying hens

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Animal Nutrition 2024年第1期16卷 395-408页

作者： marcos J.B.santos Maria C.M.M.Ludke Leandro M.silva Carlos B.V.Rabello Mércia R.Barros Fabiano s.Costa Clariana s.santos Jamille s.s.Wanderley Department of Animal science Rural Federal University of PernambucoRecifePEBrazil Department of Veterinary science Rural Federal University of PernambucoRecifePEBrazil

The present study was to evaluate the effect of trace minerals(Zn,Mn,and Cu)from complexed amino acid minerals(ZMCAA)and bis-glycinate chelated minerals(ZMCGly)in laying hen diets on performance,internal and external egg quality,yolk mineral deposition,intestinal morphometry,and bone *** 78 to 98 weeks of age,400 White LsL-Lite strain laying hens were distributed in a randomized design with 4 treatments with 10 replicates per *** were distributed in a 2×2 factorial arrangement using either Zn,Mn,and Cu of ZMCAA or ZMCGly source at 2 levels:low(20,20,and 3.5 mg/kg of Zn,Mn,and Cu,respectively)or high(40,40,and 7 mg/kg of Zn,Mn,and Cu,respectively).The analysis of variance was performed,and in cases where differences were observed,the means were compared using Tukey?s test(psource and level of trace mineral supplementation had a significant impact on the performance of laying *** fed ZMCAA had higher egg production(p=0.01),egg weight(p=0.02),egg mass(p=0.01),and lower feed conversion ratio(p=0.05)compared to those fed *** ZMCAA supplementation showed higher albumen height(p=0.01),albumen weight(p=0.01),and eggshell thickness(pposition of Zn(ppps greater for hens received *** weight(p=0.04)and bone densitometry(psmall intestine,ZMCAA resulted in longer villi(p=0.02)and shorter crypt depth(p=0.01)in the *** and ileum measurements were influenced by the level and source of trace minerals(ps fed ZMCAA exhibited superior performance,egg quality,deposition of trace minerals in the egg yolk,and bone density compared to hens fed *** this study,older laying hens supplemented with ZMCAA at lower levels demonstrated adequate levels of supplementation.

关键词： Bis-glycinates Metal-amino acids Radiodensity Trace minerals

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Global black soil distribution

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Frontiers of Agricultural science and Engineering 2024年第2期11卷 271-281页

作者： Yuxin TONG marcos E.ANGELINI Yusuf YIGINI Isabel LUOTTO Global soil partnership Land and Water DivisionFood and Agriculture Organization of the United NationsRome 00153Italy

Black soils, characterized by their thick, dark horizons enriched with organic matter, epitomize highly fertile soils. However, their fertility precipitates intense land use, engendering challenges such as soil erosion, nutrient depletion, pollution, compaction, salinization, and acidification. Notably, these soils are significant contributors to global greenhouse gas emissions, primarily due to substantial losses in soil organic carbon. Despite these challenges, black soils are pivotal for global food production. This paper delineates the implementation of digital soil mapping for the global cartography of black soils and human interference on these soils. predominantly distributed in Eastern Europe, Central and Eastern Asia, and North and south America, black soils cover an approximate area of 725 Mha, with the Russian Federation,Kazakhstan, and China collectively have over half of this area. Agriculturally,these soils underpin significant proportions of global crop yields, producing 66% of sunflower, 30% of wheat, and 26% of potato outputs. The organic carbon content in the upper 30 cm of these soils is estimated at 56 *** management of black soils is imperative for ensuring food security and addressing climate change on a global scale.

关键词： Black soils distribution map food security soil organic carbon

Relevance of Medical Imaging in the pre-Therapeutic Evaluation of Acute Intestinal Obstruction at CIMED

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Open Journal of Medical Imaging 2024年第1期14卷 31-41页

作者： Mamoudou camara Aly Mampan Koundouno siré Nabe Toumin camara Ousmane Aminata Bah Center for Medical Imaging Exploration and Diagnostics University of Conakry Conakry Guinea General surgery Department of the Kankan Regional Hospital Kankan Guinea Ministry of Health and public Hygiene Conakry Guinea General Medicine Department of the siguiri prefectural Hospital Siguiri Guinea CIRA Conakry Guinea

Objective: We initiated this work with the aim of studying the contribution of imaging in the diagnosis of acute intestinal obstruction at CIMED. patients and methods: This was a prospective, descriptive and analytical study involving 96 patients collected at the radiology and medical imaging department of CIMED, from January 2022 to January 2023. Result: The age of our patients varied between 11 and 86 years with an average age of 36 years. There was a male predominance of 64.6% compared to 35.4% for women, i.e. a sex ratio of 1.82. The notion of previous surgery was found in 61.5% of our patients. pain was present in all patients. Radiography of the Asp was performed in 89.6% of patients. It showed hydro-aerial levels in 96.5% of patients. Abdominopelvic CT was performed in 12 patients and made it possible to make the diagnosis of occlusion in all patients. The results of the positive diagnosis were concordant with those intraoperatively in 92% of cases. 8% of our patients, compared to the treatment, spontaneously resumed their transit, 91% benefited from surgical treatment and 1% died before surgery. The outcome was favorable in 80 patients or 83.3%, poor with death in 16 patients or 16.7% of cases. Conclusion: Acute intestinal obstruction remains a serious pathology for which Asp radiography often remains the only radiological examination performed urgently. However, abdominopelvic CT seems widely indicated thanks to its contribution both for the positive diagnosis and for the serious and etiological diagnoses. However, this imaging technique is largely underused in our practice due to its high cost and lack of availability.

关键词： Imaging Acute Intestinal Obstruction CIMED