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Genetic Structure of Cartagena de Indias Population Using Hypervariable Markers of Y Chromosome

Open Journal of Genetics 2015年第1期5卷 27-41页

作者： Doris E. G.-Camargo Rafael Camacho-Mejorado claudio Gómez-Alegría Angelo Alario Esther A. H.-Tobías Gustavo Mora- García marco A. M.-Ríos Rocío Gómez Doctorado en Medicina Tropical Facultad de Medicina Universidad de Cartagena Cartagena de Indias Colombia Departamento de Toxicología Cinvestav-IPN México D.F. México Departamento de Farmacia Facultad de Ciencias Universidad Nacional de Colombia Bogotá Colombia Departamento Médico Facultad de Medicina Universidad de Cartagena Cartagena de Indias Colombia Departamento de Biomedicina Molecular Cinvestav-IPN México D.F. México

Ethnicity has been associated with the incidence of diseases and consequently it is a cornerstone in medical genetic studies. It is mainly important in admixture populations, where the population stratification can produce spurious results that lead to erroneous conclusions. Consequently, population stratification has become one of the most important confounding factors in population-based genetic association studies, especially in Latino populations. Cartagena de Indias is a cosmopolitan city with dissimilar ancestry proportions due to recent miscegenation. This population mainly exhibits African and Amerindian matrilineal ancestries. Nevertheless, important asymmetries in the paternal genetic history related to the complex patterns of migration in the colonial period increase the male genetic diversity in this population. As a result of this recent admixture, population stratification has arisen, where each subpopulation is not equally represented. Consequently, the allele differences between cases and controls could be related with different frequencies among different population strata rather than the association of the genes with the disease. In order to define the patrilineal substructure of the Cartagena’s population, a total of 130 unrelated men were ancestrally studied using 15 Y-STR loci routinely employed in anthropological, forensic and population genetics. Our results show that Cartagena is an admixture population consisting of European (80%), Amerindian (10%) and African ancestries (10%), which are represented by haplogroups R1b and I2a (xI2a1), Q-M242/Q-M3, and E1b1a/E1b1b, respectively. Complex genetic patterns found in Cartagena’s population emphasize the importance to know the genetic variation in order to diminish the inconsistence for future genetic association studies. In addition, our findings illustrate the complex genetic background of Cartagena population and reinforce the need to encompass more geographic regions to generate more robust dat

关键词： Population Genetics Y-Chromosome Microsatellites Cartagena Colombia

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从地震学和工程学角度研究2016年意大利中部地震(Ⅰ)

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国际地震动态 2017年第10期38卷 2-12页

作者： marco Fasan Andrea Magrin claudio Amadio Fabio Romanelli Franco Vaccari Giuliano F.Panza 王林郑斯华 Department of Engineering and Architecture University of Trieste Piazzale Europa 1 Trieste 1-34127 Italy Department of Mathematics and Geosciences University of Trieste Via E. Weiss4 Pal. P Trieste 1-34128 Italy OGS-Istituto Nazionale di Oceanografia e di Geofisica Sperimentale Dip. C. R. S.Via Treviso 55 Udine 1-33100 Italy Department of Mathematics and Geosciences University of Trieste Via E. Weiss4 Pal. P Trieste 1-34128Italy Department of Mathematics and Geosciences University of Trieste Via E. Weiss4 Pal. P Trieste 1-34128 Italy Institute of Geophysics China Earthquake Administration Beijing China International Seismic Safety Organization (ISSO) Viale San Francesco 12 1-64031 Arsita (TE) Italy Accademia Nazionale deiLincei Palazzo Corsini-Via della Lungara 10-00165 Roma 福建省地震局福州350003 中国地震局地震预测研究所北京100036

2016年8月24日,一个强震(M6.0~6.2)袭击了位于意大利地震最活跃地区之一的亚平宁山脉中部。现场调查表明,震中区破坏严重,并造成人员伤亡,大范围文化遗产和重要建筑物遭受破坏。利用新的确定性地震危险性评估法(neo-deterministic seism... 详细信息

2016年8月24日,一个强震(M6.0~6.2)袭击了位于意大利地震最活跃地区之一的亚平宁山脉中部。现场调查表明,震中区破坏严重,并造成人员伤亡,大范围文化遗产和重要建筑物遭受破坏。利用新的确定性地震危险性评估法(neo-deterministic seismic hazard assessment,NDSHA),我们将最大确定性地震输入(maximum deterministic seismic input,MDSI)方法应用于震中区最相关的两个场地,并将结果与当前意大利建筑规范进行了比较。在完成快速工程分析后,我们结合表征地震输入的震源和场地效应,解释了造成报道的建筑环境的高地震易损性破坏的可能原因。因此,利用合适的谱加速度水平结合未来可能发生的地震事件,例如由MDSI提供的可能事件,进行建筑物设计和翻新至关重要。

关键词：地震危险性反应谱新的确定性地震危险性评估 NDSHA 最大确定性地震输入 MDSI 抗震设计

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从地震学和工程学角度研究2016年意大利中部地震(Ⅱ)

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国际地震动态 2017年第11期38卷 2-9,28页

作者： marco Fasan Andrea Magrin claudio Amadio Fabio Romanelli Franco Vaccari Giuliano F.Panza 王林(译) 郑斯华(校) Department of Engineering and Architecture University of TriestePiazzale Europa1Trieste I-34127Italy Department of Mathematics and Geosciences University of TriesteVia E.Weiss4 Pal.PTrieste I-34128Italy OGS-Istituto Nazionaledi Oceanografiaedi Geoiisica Sperimentale Dip.C.R.S.Via Treviso55Udine I-33100Italy Institute of Geophysics China Earthquake AdministrationBeijingChina International Seismic Safety Organization(ISSO) Viale San Francesco12I-64031 Arsita(TE)Italy Accademia Nazionale dti Lincei Palazzo Corsin-Via della Lungara10-00165Roma 福建省地震局福州350003 中国地震局地震预测研究所北京100036

3对建筑物和工程等方面造成的损坏受到意大利中部地震影响最大的区域是阿马特里切、阿库莫利和阿尔夸塔德尔特龙托镇,这些区域都位于离震中约15km半径内。该区域的建筑遗产主要由2-3层的老旧无钢筋砌石结构房屋组成,一些建筑的年代可以... 详细信息

3对建筑物和工程等方面造成的损坏受到意大利中部地震影响最大的区域是阿马特里切、阿库莫利和阿尔夸塔德尔特龙托镇,这些区域都位于离震中约15km半径内。该区域的建筑遗产主要由2-3层的老旧无钢筋砌石结构房屋组成,一些建筑的年代可以追溯到13世纪,一些2-5层的钢筋混凝土建筑都建于50年代早期。

关键词：意大利工程学地震学混凝土建筑地震影响建筑遗产建筑物石结构

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萎缩上颌无牙殆的处理：短种植体与骨增量后植入长种植体的比较，一项前瞻性随机临床试验在负载5个月后的试验结果

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中国口腔医学继续教育杂志 2012年第6期15卷 321-329页

作者： Pietro Felice Elisa Soardi Gerardo Pellegrino Roberto Pistilli claudio Marchetti Manlio Gessaroli marco Esposito 王瑞霞不详南京医科大学口腔医学院种植修复科江苏省210029

评价在萎缩的上颔骨．相比较于应用自体骨增量后植入长种植体（〉115mm）以支持修复体，短种植体（5～85mm）能否成为一个合适的选择。材料和方法：28位颌骨萎缩的上颌无牙耠患者，在计算机体层扫描片上测量剩余牙槽骨高度为5～9mm,至少... 详细信息

评价在萎缩的上颔骨．相比较于应用自体骨增量后植入长种植体（〉115mm）以支持修复体，短种植体（5～85mm）能否成为一个合适的选择。材料和方法：28位颌骨萎缩的上颌无牙耠患者，在计算机体层扫描片上测量剩余牙槽骨高度为5～9mm,至少5mm,随机分为两组，一组15位患者植入4～8枚短种植体（5～85mm）．另一组13位患者从髂嵴取自体骨以植入至少11．5mm的长种植体。骨块及上颌窦开窗处用可吸收的坚固屏障膜覆盖。移植物在植入种植体前潜入式愈合4个月。4个月后．戴入临时的强化树脂修复体或杆卡固位式覆盖义齿。再经过4个月后，去除临时修复体．戴入最终的螺丝固位的金属一树脂固定修复体。疗效评价包括：修复体及种植体的失败．任何并发症（包括手术后疼痛）及患者的满意度。所有的患者在种植体负重后随访5个月。结果：所有的患者都进行了种植体支持的修复重建．没有患者失访。1例双侧上颌窦提升手术因为感染失败，但是能植入短种植体。在骨增量组有1例患者失败，短种植体组有2位患者共失败2颗种植体。所有的失败发生于负重之前。骨增量组的并发症明显较多：5位骨增量患者发生了8例并发症（均主诉为髂嵴取骨后1个月疼痛）。短种植体组无并发症。所有的患者对手术满意并愿意再次接受手术。结论：本前瞻性研究提示，对于上颌骨萎缩的无牙骀患者，相比较干取自体骨进行骨增量后以植入长种植体，短种植体是合适的、费用较低且操作较快的一种选择。然而,这些初步的结果还需要大样本的临床研究且至少随访5年以上以进一步证实。

关键词：骨增量 RCT 短种植体

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Cytoreductive surgery and HIPEC after neoadjuvant chemotherapy for advanced epithelial ovarian cancer

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World Journal of Obstetrics and Gynecology 2013年第4期2卷 167-175页

作者： marco Lotti Luisa Maria Busci Luca Campanati Fausto Catena Federico Coccolini Naoual Bakrin Pierandrea De Iaco Giorgio Ercolani Giuseppe Grosso Michele Pisano Elia Poiasina Diego Rossetti Martina Rossi claudio Zamagni Paolo Bertoli Antonio Daniele Pinna Luigi Frigerio Luca Ansaloni Unit of General Surgery 1 Papa Giovanni XXIII Hospital 24128 Bergamo Italy Unit of Gynecology and Obstetrics Papa Giovanni XXIII Hospital 24128 Bergamo Italy Unit of General Surgery St.Orsola-Malpighi University Hospital 40138 Bologna Italy Department of Gynecology Lyon Sud Hospital69310 Pierre Benite France Unit of Gynecology and Obstetrics St.Orsola-Malpighi University Hospital V40138 Bologna Italy Medical Oncology St.Orsola-Malpighi University Hospital 40138 Bologna Italy

AIM: To reduce postoperative complications and to make possible an optimal cytoreduction, neoadjuvant chemotherapy(NACT) followed by interval debulking surgery has been applied with encouraging results. METHODS: Between December 2009 and February 2012, patients with stage ⅢC-Ⅳ epithelial ovarian cancer(EOC) underwent diagnostic laparoscopy, to assess the feasibility of optimal debulking surgery. The modifi ed Fagotti score was applied to assess the feasibility of resection with zero residual tumor. Patients who were not candidate for upfront debulking surgery were submitted to NACT, then reassessed according to the RECIST 1.1 criteria and submitted to cytoreductive surgery(CRS) and hyperthermic intraperitoneal chemotherapy(HIPEC) if they showed clinical response or stable disease. The remaining cycles of adjuvant systemic chemotherapy(ASCT) were administered postoperatively, to complete 6 cycles of systemic ***: Nine patients were included. Clinical response to NACT was complete in 3 patients and partial in 5 patients; one patient had stable disease. All patients underwent CRS resulting in CC0 disease prior to HIPEC. Average operative time was 510 min. Average intensive care unit stay was 2 d. Average postoperative hospital stay was 25 d. No postoperative mortality was observed. One patient experienced pelvic abscess. One patient refused ASCT. The remaining 8 patients started ASCT. Average time to chemotherapy was 36 d. All patients are alive, with an average follow up of 11 mo. Eight patients are disease-free at follow ***: HIPEC after CRS for advanced EOC is feasible with acceptable morbidity and mortality. NACT may increase the chance for achieving complete cytoreduction. Phase 3 studies are needed to determine the effects of HIPEC on survival.

关键词： Peritoneal carcinomatosis Ovarian cancer Cytoreductive surgery Intraperitoneal chemotherapy Hyperthermic intraperitoneal chemotherapy Hyperthermia

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Carbon Burial in Young Tropical Reservoirs Is Higher at Lower Latitudes*

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Journal of Geoscience and Environment Protection 2021年第12期9卷 84-99页

作者： Elizabeth Sikar marco Aurelio dos Santos Ana Carolina Moterani Isabella Matvienko Ana Carla Martins Veras Juliana Pinto Pereira Dias Orleno Marques da Silva Junior claudio Pavani Marcelo Amorim Teodosio das Neves Milisse Nzualo Ayr Manoel Portilho Bentes Junior Rogerio Duarte Construmaq Sã o Carlos S&#227 o Carlos SP Brazil Programa de Planejamento Energético da Universidade Federal do Rio de Janeiro Brazil Laboratório de Energias Renováveis e Estudos Ambientais da Universidade Federal do Rio de Janeiro Brazil Instituto de Pesquisas Científicas e Tecnológicas do Estado do Amapá Brazil Programa de Pós-Graduaç ã o em Geografia da Universidade Federal do Amapá Brazil

Man-made environments such as tropical hydroelectric reservoirs alter the preexisting carbon (C) cycle and remove C from circulation through burial in sediments. Carbon burial (CB) was measured using the silica-tracer method during four field surveys in the less than six-year-old Belo Monte tropical reservoir. Fresh C sedimentation was also measured. Belo Monte’s CB median rate 276 (n = 84;min 0;max 352,625 mg C·m-2·d-1) is within the range (230 to 436 mg C·m-2·d-1) of CB rates measured further downstream at the Xingu Ria and higher than the averaged over 50 years oceanic rate 244 mg C·m-2·d

关键词： Carbon Burial Sediments Hydroelectric Reservoirs

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Acellular Amniotic Membrane Patch Regeneration for Burn Injury: The Future for Wound Healing

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Journal of Biomedical Science and Engineering 2019年第8期12卷 409-413页

作者： Tayná Dias Kalyane Machado Kátia Renata Antunes Kochla Ricardo Cunha marco André Cardoso Rossana Baggio Simeoni Vinicius Coneglian Santos Péricles Varella Gomes Luiz claudio Sobrinho do Nascimento Maria Elisa Brum do Nascimento Luiz Cesar Guarita-Souza Alessandro Brawerman Julio Cesar Francisco School of Health Sciences Positivo University Curitiba Brazil School of Medical Sciences Pontifical Catholic University of Paraná Curitiba Brazil The Paraná Institute of Technology Curitiba Brazil Gel Lab Michigan State University East Lansing USA

Acellular amniotic membrane (AAM) is a biodegradable and biocompatible natural that has a wide range of applications in the field of pharmaceutics, biomedical, chemical and cosmetics industry. One of the most interesting characteristics of AAM is its antibacterial and anti-inflammatory, anti-angiogenic, anti-fibrosis activity is an attractive approach for treating inflammatory disorders, wounds, and burns. The isolated use of AAM may not be sufficient to produce an adequate anti-inflammatory and antimicrobial effect to fulfill different purposes, has attracted considerable attention that has similar properties to the native tissues. This mini-review offers a focuses on modern aspects of the biomaterials, growth factors, biocompatibility, and acellular matrix which are the basic elements for use in the tissue regeneration and replacement after an injury.

关键词： Skin Regeneration Amniotic Membrane Wound Healing Tissue Engineering

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Sonographic assessment of a suspected biloma:A case report and review of the literature

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World Journal of Radiology 2013年第5期5卷 220-225页

作者： claudio Tana Patrizio D'Alessandro Armando Tartaro marco Tana Andrea Mezzetti Cosima Schiavone Unit of Internistic Ultrasound "G.d'Annunzio" University Department of Medicine and Science of Aging "G.d'Annunzio" University Department of Neurosciences and Imaging "G.d'Annunzio" University

A biloma is a rare disease characterized by an abnormal intra-or extrahepatic bile collection due to a traumatic or spontaneous rupture of the biliary *** findings are *** diagnosis is usually suspected on the basis of a typical history(right upper quadrant abdominal pain,chills,fever and recent abdominal trauma or surgery) and is confirmed by detection of typical radiologic *** report the case of a patient with a history of previous cholecystectomy for lithiasis who presented with clinical symptoms and laboratory data suggestive of acute *** studies also revealed the presence of a chronic and asymptomatic biloma,which could be mistaken for a *** atypical location and ultrasound findings suggested an alternative *** therefore reviewed the known literature for bilomas,focusing on the role of ultrasonography,which can reveal some typical aspects,such as location and imaging *** that ultrasound plays a key role in the assessment of a suspected biloma in patients with appropriate history and clinical features and provides valuable diagnostic clues even in the absence of these.

关键词： Biloma Bile leakage Ultrasound Focused assessment with sonography for trauma Contrast-enhanced ultrasound Magnetic resonance cholangiography

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The enhanced X-ray Timing and Polarimetry mission—eXTP

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Science China(Physics,Mechanics & Astronomy) 2019年第2期62卷 3-27页

作者： ShuangNan Zhang Andrea Santangelo marco Feroci YuPeng Xu FangJun Lu Yong Chen Hua Feng Shu Zhang Sφren Brandt Margarita Hernanz Luca Baldini Enrico Bozzo Riccardo Campana Alessandra De Rosa YongWei Dong Yuri Evangelista Vladimir Karas Norbert Meidinger Aline Meuris Kirpal Nandra Teng Pan Giovanni Pareschi Piotr Orleanski QiuShi Huang Stephane Schanne Giorgia Sironi Daniele Spiga Jiri Svoboda Gianpiero Tagliaferri Christoph Tenzer Andrea Vacchi Silvia Zane Dave Walton ZhanShan Wang Berend Winter Xin Wu Jean J.M.in't Zand Mahdi Ahangarianabhari Giovanni Ambrosi Filippo Ambrosino marco Barbera Stefano Basso Jörg Bayer Ronaldo Bellazzini Pierluigi Bellutti Bruna Bertucci Giuseppe Bertuccio Giacomo Borghi XueLei Cao Franck Cadoux Francesco Ceraudo TianXiang Chen Yu Peng Chen Jerome Chevenez Marta Civitani Wei Cui WeiWei Cui Thomas Dauser Ettore Del Monte Sergio Di Cosimo Sebastian Diebold Victor Doroshenko Michal Dovciak YuanYuan Du Lorenzo Ducci QingMei Fan Yannick Favre Fabio Fuschino JoséLuis Ga'lvez Min Gao MingYu Ge Olivier Gevin marco Grassi QuanYing Gu YuDong Gu DaWei Han Bin Hong Wei Hu Long Ji ShuMei Jia WeiChun Jiang Thomas Kennedy Ingo Kreykenbohm Irfan Kuvvetli claudio Labanti Luca Latronico Gang Li MaoShun Li Xian Li Wei Li ZhengWei Li Olivier Limousin HongWei Liu XiaoJing Liu Bo Lu Tao Luo Daniele Macera Piero Malcovati Adrian Martindale Malgorzata Michalska Bin Meng Massimo Minuti Alfredo Morbidini Fabio Muleri Stephane Paltani Emanuele Perinati Antonino Picciotto claudio Piemonte JinLu Qu Alexandre Rachevski Irina Rashevskaya Jerome Rodriguez Thomas Schanz ZhengXiang Shen LiZhi Sheng JiangBo Song LiMing Song Carmelo Sgro Liang Sun Ying Tan Phil Uttley Bo Wang DianLong Wang GuoFeng Wang Juan Wang LangPing Wang YuSa Wang Anna L.Watts XiangYang Wen Jörn Wilms ShaoLin Xiong JiaWei Yang Sheng Yang YanJi Yang Nian Yu WenDa Zhang Gianluigi Zampa Nicola Zampa Andrzej A.Zdziarski AiMei Zhang ChengMo Zhang Fan Zhang Long Zhang Tong Zhang Yi Zhang XiaoLi Zhang ZiLiang Zhang BaoSheng Zhao ShiJie Zheng Yu Peng Zhou Key Laboratory for Particle Astrophysics Institute of High Energy PhysicsChinese Academy of Sciences Institut für Astronomie und Astrophysik Eberhard Karls Universität INAF-Istituto di Astrofisica e Planetologia Spaziali INFN-Roma Tor Vergata Via della Ricerca Scientifica 1 Department of Engineering Physics and Center for Astrophysics Tsinghua University DTU Building 327DK-2800 Kongens Institute of Space Sciences 08193 Cerdanyola del Valles Institut d’Estudis Espacials de Catalunya Sezione di Pisa Istituto Nazionale di Fisica NucleareLargo Bruno Pontecorvo3 Department of Astronomy University of Genevachemin d’Ecogia 16 Osservatorio di Astrofisica e Scienza Dello Spazio di Bologna Istituto Nazionale di Astofisica Astronomical Institute Czech Academy of Sciences Max Planck Institute for Extraterrestrial Physics Giessenbachstr.1 CEA Paris-Saclay/IRFU Beijing Institute of Spacecraft System Engineering CAST Osservatorio Astronomico di Brera Istituto Nazionale di Astofisica Space Research Center Polish Academy of Sciences Key Laboratory of Advanced Material Microstructure of Education Ministry of China Institute of Precision Optical EngineeringSchool of Physics Science and EngineeringTongji University Department of Physics and Center for Astrophysics Tsinghua University Universita’degli Studi di Udine Via delle Scienze 206 Mullard Space Science Laboratory University College London Department of Nuclear and Particle Physics University of Geneva SRON Netherlands Institute for Space Research Politecnico di Milano Sezione di Perugia Istituto Nazionale di Fisica Nucleare Dipartimento di Fisica e Chimica Fondazione Bruno Kessler Dr.Karl Remeis-Observatory and Erlangen Centre for Astroparticle Physics Universität Erlangen-Nürnberg University of Pavia Department of ElectronicsInformation and Biomedical Engineering and INFN Pavia Sezione di Torino Istituto Nazionale di Fisica NucleareVia Pietro Giuria1 Department of Physics and Astronomy University of Leicester Sezione di Trieste Istituto Nazionale di Fisica Nucleare

In this paper we present the enhanced X-ray Timing and Polarimetry mission—eXTP. eXTP is a space science mission designed to study fundamental physics under extreme conditions of density, gravity and magnetism. The mission aims at determining the equation of state of matter at supra-nuclear density, measuring effects of QED, and understanding the dynamics of matter in strong-field gravity. In addition to investigating fundamental physics, eXTP will be a very powerful observatory for astrophysics that will provide observations of unprecedented quality on a variety of galactic and extragalactic objects. In particular, its wide field monitoring capabilities will be highly instrumental to detect the electro-magnetic counterparts of gravitational wave *** paper provides a detailed description of:(1) the technological and technical aspects, and the expected performance of the instruments of the scientific payload;(2) the elements and functions of the mission, from the spacecraft to the ground segment.

关键词： X-ray instrumentation X-ray polarimetry X-ray timing space mission:eXTP

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The Neurologist in the Emergency Room: Prospective Study of the Neurological Emergency Group in Lombardia

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Journal of Health Science 2019年第4期7卷 254-261页

作者： MariaLuisa Delodovici marco Mauri Megi Meneri marco Gallazzi Elena Ballabio Giuseppina Borutti Maria Vittoria Calloni Elisa Candeloro Bruno Censori claudio De Piazza Laura Fusi Franca Mazzucchelli Ignazio Santilli Elisabetta Forapani Chiara Scaccabarozzi Maria Sessa Lucia Tancredi Massimiliano Braga Dept. of Neurology and Stroke Unit Ospedale di Circolo e Fondazione MacchiUniversità dell’InsubriaASST-Settelaghile Luigi Borri 57 21100 VareseItaly Dept. of Neurology Ospedale di Desio (MB) Director G. Mazzini 1 20832 Desio (MB)Italy Dept. of Neurology ASST Lecco-Ospedale A. Manzonidell’Eremo 9/11 23900 LeccoItaly Dept. of Neurology Ospedale di Cremona ASST Cremona Directorle Concordia 1 26100 CremonaItaly Dept. of Neurology Ospedale Sant’Anna ComoRavona 20 22042 SFermo della BattagliaComoItaly Dept. of Neurology Ospedale di Vimercate (MB) Santi Cosma e Damiano 10 20871 Vimercate (MB)Italy Dept. of Neurology Ospedale S. Carlo BorromeoA. Mosca 12 20152 MilanoItaly Dept. of Neurology Director Ospedale Civile di VogheraVolturno 14 Voghera 27058 (PV)Italy Dept. of Neurology Ospedale di Legnano ASST Ovest MilanesePapa Giovanni Paolo II20025 Legnano (MI)Italy Dept. of Neurology Fondazione IRCCS C. Mondino Mondino 2Pavia 27100Italy Dept. of Neurology ASST Papa Giovanni XXIII Piazza OMS 1 24127 BergamoItaly Dept. of Neurology Ospedale Valduce ComoDante Alighieri 11 22100 ComoItaly Dept. of Neurology Ospedale di Saronno ASST Valle olonaPiazzale Borella 1 Saronno 21047 (VA)Italy Dept. of Neurology Ospedale S. Antonio Abate Gallarate. Pastori 4 21013 Gallarate VareseItaly

Purpose of the work was to quantify the workloads and the neurologist’s commitment in ER, to verify the management of urgencies and appropriateness of neurological counseling requests. Neurologic emergencies are frequent in elderly patients and are associated with high morbidity and mortality. Due to the aging population, neurologic pathologies in emergency room (ER) are widely expected to increase. The role of the neurologist in this context is controversial. Methods: in 14 operative units of neurology a prospective collection of neurological evaluations in ER was carried out using boards of detection of the most frequent neurological clinical pictures seen in the course of a week. Data were collected from 738 cases. Attention was focused on cerebrovascular diseases (CVD), impairment of consciousness, epilepsy, headache, dizziness, head trauma and disorders of the peripheral nervous system (PNS). Achievements: neurological consultations were on average 5% of total accesses to ER. The most common pathology seen was ischemic stroke. After counseling most patients were discharged home. The CVD required the greatest commitment to the specialist. The usefulness of the specialized neurological “filter” has been confirmed in a non-simple operative context, aimed at optimizing the appropriateness of the hospitalization and the economy of the diagnostic path.

关键词： Emergency room neurological diseases neurology workload

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