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Fulminant Hepatitis Associated with Chronic Consumption of 3,4-Methylenedioxy-Methamphetamine;Case Report

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Open Journal of Gastroenterology 2024年第5期14卷 161-166页

作者： Ulises Solis Gomez Gustavo Adolfo Hernández Valdez Juan Antonio Contreras Escamilla Ivan Alejandro Medina Jimenez Jorge Morales Rojas Jocelyn Nataly Quintero Melendez marco Antonio González Villar Department of Internal Medicine ISSSTE APP General Hospital of Tepic Tepic Nayarit Mexico

The amphetamine derivative 3,4-methylenedioxymethamphetamine (MDMA), also called ecstasy, is a neurotoxin widely consumed among young people that has increased in recent years because it is a recreational drug, of which immediate effects are known such as a greater sensation of well-being, extroversion, increased sensory perception. However, its long-term effects have been described very little in the medical literature, including damage to the heart, central nervous system, kidney, etc. One of its little-known effects is hepatotoxicity, of which few cases are known associated with fulminant hepatitis, which is a rapidly deteriorating condition that is generally associated with a syndrome of multiple organ dysfunction and death. Therefore, it is very important to know this type of damage in the short and long term. The following case is of a 39-year-old man who came to our service due to jaundice syndrome and the only history of MDMA consumption, who as the days went by met the criteria for fulminant liver failure, with damage to multiple organs (organ dysfunction syndrome).

关键词： Fulminant Hepatitis Acute Liver Failure Methamphetamine Severe Acute Liver Failure in a User of Drugs of Abuse Hepatology

University Corporate Governance in the Literature From 2019 to 2024

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Journalism and Mass Communication 2024年第3期14卷 179-188页

作者： María del Rosario Molina González María Teresa Gaxiola Sánchez María de Jesús Camargo Pacheco marco Antonio Velderrain Rodríguez Rafael Campoy Mendoza Cruz García Lirios Universidad de Sonora NavojoaMexico

Anti-pandemic policies impacted the governance of Higher Education Institutions(HEIs)through confinement and distancing *** an impact was observed in the identity,reputation,and image of the HEI in the face of the health *** objective of this work was to establish an empirical contrast between the theoretical structure consulted regarding the evaluations of summaries published from 2019 to 2024 by judges.A documentary,cross-sectional,and retrospective study was carried out with a sample of sources indexed in international *** results demonstrate that image and age regulate the impact of identity and income on *** relation to the state of the art,it is recommended to extend the study to sociocultural,demographic,economic,and educational variables in order to anticipate the transition from university governance to corporate governance.

关键词： COVID governance model nodes neural networks

How physical and motor training affect cognitive performance: lessons from an inflammatory molecule

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Neural Regeneration Research 2022年第12期17卷 2689-2690页

作者： Margherita Maffei marco Mainardi Institute of Clinical Physiology National Research Council(IFC-CNR)and Obesity/Lipodystrophies CenterPisa University HospitalPisaItaly Neuroscience Institute National Research Council(IN-CNR)PisaItaly

Our phenotype includes not only physical features,but also behavioral outputs such as motor schemes and learned skills,and is the result of a complex interaction between genetic background and *** fact,a good fraction of last decades’biomedical efforts were dedicated to understanding how different elements(e.g.,genetic polymorphisms,lifestyle components)participate in this interplay,ultimately contributing to affect a given phenotype up to the point of steering it towards *** and epigenetic elements are relatively easy to analyze individually using a reductionist approach,for instance via loss-or gain-of-function studies in cellular and animal models;the effects of nutrients,drugs,pollutants can be similarly tested as single specific stimuli.

关键词： instance drugs lesson

Vibrationally resolved optical excitations of the nitrogen-vacancy center in diamond

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npj Computational Materials 2022年第1期8卷 2258-2266页

作者： Yu Jin marco Govoni Giulia Galli Department of Chemistry University of ChicagoChicagoIL60637USA Pritzker School of Molecular Engineering University of ChicagoChicagoIL60637USA Materials Science Division and Center for Molecular Engineering Argonne National LaboratoryLemontIL60439USA

A comprehensive description of the optical cycle of spin defects in solids requires the understanding of the electronic and atomistic structure of states with different spin multiplicity,including singlet states which are particularly challenging from a theoretical *** present a general framework,based on spin-flip time-dependent density function theory,to determine the excited state potential energy surfaces of the many-body singlet states of spin defects;we then predict the vibrationally resolved absorption spectrum between singlet shelving states of a prototypical defect,the nitrogen-vacancy center in *** results,which are in very good agreement with experiments,provide an interpretation of the measured spectra and reveal the key role of specific phonons in determining absorption processes,and the notable influence of non-adiabatic *** insights gained from our calculations may be useful in defining strategies to improve infrared-absorption-based magnetometry and optical pumping *** theoretical framework developed here is general and applicable to a variety of other spin defects and materials.

关键词： vacancy resolved singlet

Two-Layer High-Throughput:Effective Mass Calculations Including Warping

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Engineering 2022年第3期8卷 74-80页

作者： Andrew Supka Nicholas A.Mecholsky marco Buongiorno Nardelli Stefano Curtarolo marco Fornari Department of Physics&Science of Advanced Materials Program Central Michigan UniversityMount PleasantMI 48859USA Department of Physics&Vitreous State Laboratory The Catholic University of AmericaWashingtonDC 20064USA Department of Physics&Department of Chemistry University of North TexasDentonTX 76203USA Center for Autonomous Materials Design Duke UniversityDurhamNC 27708USA Department of Mechanical Engineering and Materials Science Duke UniversityDurhamNC 27708USA

In this paper,we perform two-layer high-throughput *** the first layer,which involves changing the crystal structure and/or chemical composition,we analyze selected Ⅲ-Ⅴ semiconductors,filled and unfilled skutterudites,as well as rock salt and layered *** second layer searches the full Brillouin zone(BZ)for critical points within 1.5 eV(1 eV=1.602176×10^(-19)J)of the Fermi level and characterizes those points by computing the effective *** introduce several methods to compute the effective masses from first principles and compare them to each *** approach also includes the calculation of the density-of-states effective masses for warped critical points,where traditional approaches fail to give consistent results due to an underlying non-analytic behavior of the critical *** demonstrate the need to consider the band structure in its full complexity and the value of complementary approaches to compute the effective *** also provide computational evidence that warping occurs only in the presence of degeneracies.

关键词： High-throughput Electronic structure Band warping Effective mass

Inverse design of truss lattice materials with superior buckling resistance

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npj Computational Materials 2022年第1期8卷 2361-2372页

作者： marco Maurizi Chao Gao Filippo Berto Department of Mechanical and Industrial Engineering Norwegian University of Science and Technology(NTNU)Trondheim7491Norway

Manipulating the architecture of materials to achieve optimal combinations of properties(inverse design)has always been the dream of materials scientists and *** represent an efficient way to obtain lightweight yet strong materials,providing a high degree of *** massive research has been done on lattice architectures,the inverse design problem of complex phenomena(such as structural instability)has remained *** deep neural network and genetic algorithm,we provide a machine-learning-based approach to inverse-design non-uniformly assembled *** basic building blocks,our approach allows us to independently control the geometry and topology of periodic and aperiodic *** an example,we inverse-design lattice architectures with superior buckling performance,outperforming traditional reinforced grid-like and bio-inspired lattices by~30–90%and 10–30%,*** results provide insights into the buckling behavior of beam-based lattices,opening an avenue for possible applications in modern structures and infrastructures.

关键词： buckling inverse lattice

The intriguing giant deer from the Bate cave (Crete): could paleohistological evidence question its taxonomy and nomenclature?

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Integrative Zoology 2022年第1期17卷 54-77页

作者： Maria Rita PALOMBO marco ZEDDA CNR-IGAG c/o Department of Earth Sciences Sapienza UniversityRomaItaly Department of Veterinary Medicine University of SassariItaly

The research describes for the first time a possible case of pituitary gigantism in fossil mammals,precisely in *** pathology was detected in 2 long bones(tibia and metatarsus)belonging to an individual of an unusual large size found at the Bate cave(Rethymnon,Northern Crete).It formed the basis of Candiacervus major,the largest among the endemic deer species recorded in the Pleistocene-Early Holocene of *** and histomorphological examinations highlighted a reduction in cortical bone thickness and the presence of wide lacunae inside of the bone *** pathological conditions suggest a pituitary gigantism diagnosis also supported by some morphological evidence,such as the extremely elongated distal part of the metatarsal diaphysis,the proportionally small proximal epiphysis,and some bone *** diagnosis of a case of pituitary gigantism as presumed responsible for the extraordinary elongation of the tibia and the metatarsal bone is intriguing as they are,respectively,the paratype and the holotype of the *** species represents a case of a deviation from the“island rule”in Pleistocene large *** new evidence recommends a taxonomic and nomenclatural revision of this *** main outcomes of this research are as follows:(i)a case of pituitary gigantism is described for the first time in an extinct mammal;(ii)it is underlined that paleohistology may provide interesting clues for disentangling taxonomic and nomenclatural issues;(iii)one of the very few cases of gigantism in insular mammals is being questioned.

关键词： Candiacervus major Cretan deer island rule paleohistology pituitary gigantism

为情感共鸣的全面电影人辩护:谢晋电影模式与情节剧的持久性

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电影理论研究（中英文） 2024年第1期6卷 94-99页

作者： [意]马可・穆勒郑泉(译) 上海大学上海电影学院上海大学电影艺术研究中心

中国传统的伦理体系与新中国成立所带来的新思想之间的调和形成了一种广受欢迎的电影形式,这在西方被称为“情节剧”。然而,这个类别从未成为中国电影类型系统的一部分。谢晋是中国最能代表完整和复杂情感共鸣的全面电影人,在他独特的... 详细信息

中国传统的伦理体系与新中国成立所带来的新思想之间的调和形成了一种广受欢迎的电影形式,这在西方被称为“情节剧”。然而,这个类别从未成为中国电影类型系统的一部分。谢晋是中国最能代表完整和复杂情感共鸣的全面电影人,在他独特的电影风格中,情节剧始终服务于纯粹的场面调度,同时他的“政治情节剧”和“家庭情节剧”构成了私人与公共之间的冲突、社会中(可以解决的)矛盾的戏剧化呈现。正是由于像谢晋这样的电影巨匠的存在,情节剧的想象力一直贯穿着整个中国近代电影史,今天他的电影仍然在向中国资深和年轻导演传授如何不惧怕电影中的情感表达。

关键词：家庭情节剧政治活动家电影情感共鸣的全面电影人情感吸引力象征性定位

How to avoid overtreatment of benign colorectal lesions:Rationale for an evidence-based management

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World Journal of Gastroenterology 2022年第47期28卷 6619-6631页

作者： marco Bustamante-Balén Gastrointestinal Endoscopy Unit Gastrointestinal Endoscopy Research GroupHospital Universitari Ⅰ Politècnic La FeHealth Research Institute Hospital La Fe(ⅡSLaFe)Valencia 46026Spain

Implementing population-based screening programs for colorectal cancer has led to an increase in the detection of large but benign histological ***,endoscopic mucosal resection can be considered the standard technique for the removal of benign lesions of the colon due to its excellent safety profile and good clinical ***,several studies from different geographic areas agree that many benign colon lesions are still referred for ***,the referral rate to surgery is not decreasing over the years,despite the theoretical improvement of endoscopic resection *** article will review the leading causes for benign colorectal lesions to be referred for surgery and the influence of the endoscopist experience on the referral *** will also describe how to categorize a polyp as complex for resection and consider an endoscopist as an expert in endoscopic *** finally,we will propose a framework for the accurate and evidence-based treatment of complex benign colorectal lesions.

关键词： Colorectal polyps Endoscopic mucosal resection Colorectal surgery