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Advances in Bioscience and Biotechnology 2010年第1期1卷 1-6页

作者： marcia regina ferreira geraldo Carla Cristina Arroteia Carlos Kemmelmeier 不详

Fungi of the genus Fusarium are well known plant pathogens, cause several vascular diseases and are producers of toxins. In vitro assays evaluated the effects of Neem (Azadirachta indica) oil on the diameter of colonies, dry weight, spore production, spore viability and production of Fusaric Acid toxin on Fusarium oxysporum f. sp. medicagenis and Fusarium subglutinans isolates. Effects of Neem oil were analyzed at concentrations 0.25%, 0.5% and 1% in Czapek Yeast Agar medium. The production of Fu- saric acid was determined by Thin Layer Chromatography and quantified by UV spectrophotometry. Neem oil showed inhibitory effects on the isolates tested, although they varied according to type of isolate and oil concentration. Neem oil was efficient in reducing the colonies’ diameter and dry weight in concentration-dependent manner. Neem oil was efficacious at higher concentration in the decrease of sporulation. Spore germination was affected by Neem oil when the spore was grown in Neem-contained medium as when the spore emerged from a culture in a Neem medium. Neem oil decreased and even inhibited the production of Fusaric acid by the assayed isolates. Since these isolates are plant pathogens and producers of Fusaric acid, Neem oil may be introduced as an integral item in the management of host plants.

关键词： Fusarium Azadirachta Indica Fusaric Acid Antifungal Activity

Investigation of possible relationship between atopic dermatitis and salivary biomarkers,stress,and sleep disorders

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World Journal of Clinical Cases 2023年第17期11卷 3958-3966页

作者： Juliany Estefan Dennis de Carvalho ferreira Fernanda Sampaio Cavalcante Kátia regina Netto dos Santos marcia Ribeiro Dermatologia Pediátrica Universidade Federal do Rio de JaneiroRio de Janeiro 21941630Brazil Faculdade de Enfermagem Departamento de Fundamentos de EnfermagemUniversidade do Estado do Rio de JaneiroRio de Janeiro 20551030Brazil Departamento de Clínica Médica Instituto de Ciências MédicasUniversidade Federal do Rio de JaneiroCampus MacaéRio de Janeiro 27930-560Brazil Departamento de Microbiologia Médica Instituto de Microbiologia Paulo de GóesUniversidade Federal do Rio de JaneiroRio de Janeiro 21941630Brazil Genética médica Instituto de Puericultura e Pediatria Martagão Gesteira/Universidade Federal do Rio de JaneiroRio de Janeiro 21941630Brazil

Atopic dermatitis(AD)is a chronic,relapsing,multifactorial inflammatory disease with genetic,environmental,and immunological *** quality of life and sleep of patients and their families are affected by AD,which triggers stress,described as one of the factors that worsens *** biomarkers such as cortisol,alpha-amylase,chromogranin A,and melatonin have been associated with stress and sleep ***,the evaluation of stress and sleep disorders using salivary biomarkers in AD patients is *** review aims to describe the possible relationship between atopic dermatitis and stress,sleep disorders,and salivary biomarkers,seeking to contribute to better understanding and clinical management of *** descriptive study is characterized as a narrative literature review.A literature search was conducted of studies published in English and Portuguese between January 2012 and October 2022 that are available in electronic media from various databases,such as Scientific Electronic Library Online,Latin American and Caribbean Literature on Health Sciences,and *** is associated with different degrees of impact on the lives of individuals who present with the *** stress may induce changes in saliva composition and worsen AD;at the same time,the severity of the disease may be associated with emotional *** studies are needed to assess and correlate AD severity,stress,and sleep disturbances with salivary biomarkers in order to better understand this association.

关键词： Atopic dermatitis Sleep Psychological stress Chromogranin A Melatonin Cortisol

Acaricidal activity of Derris floribunda essential oil and its main constituent

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Asian Pacific Journal of Tropical Biomedicine 2017年第9期7卷 791-796页

作者： Ana Claudia Fernandes Amaral Aline de SRamos marcia Reis Pena Jose Luiz Pinto ferreira Jean Michel SMenezes geraldo JNVasconcelos Neliton Marques da Silva Jefferson Rocha de Andrade Silva Lab de Plantas Medicinais e Derivados Depto de Quimica de Produtos NaturaisFarmanguinhosFundacao Oswaldo CruzRio de JaneiroRJBrazil Lab de Entomologia e Acarologia Agricola Faculdade de Ciencias AgrariasUniversidade Federal do AmazonasManausAMBrazil Lab de Cromatografia Depto de QuímicaUniversidade Federal do AmazonasManausAMBrazil 4Instituto de Ciencias Exatas e TecnologiaUniversidade Federal do AmazonasItacoatiaraAMBrazil

Objective: To evaluate the acaricidal activity of the essential oil obtained from roots of Derris floribunda(D. floribunda)(Miq.) Benth, and its main constituent nerolidol against the Mexican mite Tetranychus mexicanus(T. mexicanus)(Mc Gregor).Methods: The essential oil from the roots of D. floribunda collected in the Amazon region(Brazil) was obtained by hydrodistillation. Its chemical composition was determined by GC–MS analysis. The acaricidal activities of this essential oil and nerolidol,were evaluated by recording the number of dead females(mortality) and eggs(fertility).Results: The essential oil showed sesquiterpenes as major volatile components. Nerolidol, the main component, represented 68.5% of the total composition of the essential oil. D. floribunda essential oil and nerolidol showed acaricidal activity, with LC_(50) of9.61 mg/m L air and 9.2 mg/m L air, respectively, over a 72 h period. In addition, both the essential oil and nerolidol significantly reduced the fecundity of T. ***: Due to the economic importance of T. mexicanus and the lack of new pesticides, our data are very promising in the search for efficient and safer acaricidal products. Furthermore, this is the first report about the chemical composition and bioactivity of the essential oil of the Amazon plant species D. floribunda.

关键词： Acaricidal activity Essential oil Nerolidol Organic agriculture Sesquiterpenes Timb

Role of lysophosphatidic acid and its receptors in health and disease:novel therapeutic strategies

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Signal Transduction and Targeted Therapy 2021年第3期6卷 630-647页

作者： Luiz Henrique Medeiros geraldo Tania Cristina Leite de Sampaio Spohr Rackele ferreira do Amaral Anna Carolina Carvalho da Fonseca Celina Garcia Fabio de Almeida Mendes Catarina Freitas Marcos Fabio dosSantos Flavia regina Souza Lima Institute de Ciencias BiomedicasUniversidade Federal do Rio de JaneiroRio de JaneiroBrazil Universite de Paris PARCCINSERMF-75015 ParisFrance Institute Estadual do Cerebro Paulo Niemeyer-Secretaria de Estado de Saude Rio de JaneiroBrazil Instituto de Saiide de Nova Friburgo Universidade Federal Fluminense28625-650 Nova FriburgoBrazil

Lysophosphatidic acid(LPA)is an abundant,bioactive phospholipid,with multiple functions both in development and in pathological ***,we review the literature about the differential signaling of LPA through its specific receptors,which makes this lipid a versatile signaling *** differential signaling is important for understanding how this molecule can have such diverse effects during central nervous system development and angiogenesis;and also,how it can act as a powerful mediator of pathological conditions,such as neuropathic pain,neurodegenerative diseases,and cancer ***,we review the preclinical and clinical uses of Autotaxin,LPA,and its receptors as therapeutic targets,approaching the most recent data of promising molecules modulating both LPA production and *** review aims to summarize the most update knowledge about the mechanisms of LPA production and signaling in order to understand its biological functions in the central nervous system both in health and disease.

关键词： therapeutic clinical diseases

Augmented Reality Applied to Building Assessment with Building Information Model Visualization

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Journal of Civil Engineering and Architecture 2014年第9期8卷 1129-1137页

作者： marcia regina de Freitas regina Coeli Ruschel School of Civil Engineering University of Campinas Sao Paulo 13083-952 Brazil

AR （augmented reality） is a technology that adds information to the real world adding virtual elements to its visualization in real time. AR used in AECO （architectural, engineering, construction and operations） can contribute in augmenting visualization during design, construction and operation of the buildings. This article presents a study that applies AR to building assessment with BIM （building information） model visualization. The use of AR on existing applications for smart phones and tablets is validated. AR proposed an adaptation of the method of POE （post-occupancy evaluation） subsidized. Traditional POE process model involves three phases： planning, conducting and applying. In order to incorporate AR, it is proposed a total restructuring of the planning phase, developing the research instruments in three steps： 3D modeling, model treatment and AR application development. It was observed that for POE studies, the 3D models are in large scale and need to be detailed for precise comparison. BIM models for facility management, representing building use situation, are of the highest level of detail. A balanced point between simplicity and representativeness was the solution adopted in this experiment for uploading and downloading performance issues. This article presents and discusses findings for the new proposition for the activity of research instruments development for the planning phase of POE with AR as well as initial tests with first results and difficulties faced.

关键词： Construction management assessment augmented reality building information model

Phytotoxic effect of Sesbania virgata(Cav.) *** seeds of agronomic and forestry species

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Journal of Forestry Research 2015年第2期26卷 339-346页

作者： Vera Lygia El Id Bárbara Vale da Costa Daiane Salete Broch Mignoni Marina Belloni Veronesi Kelly Simoes marcia regina Braga Nelson Augusto dos Santos Junior Seed Department Institute of Botany Plant Physiology and Biochemistry Department Institute of Botany

Sesbania virgata（Cav.） *** a pioneer species native to South America able to release allelochemicals that affect germination and development of other plant *** aim of this work was to evaluate the allelopathic effect of *** on the germination and development of co-occurring species from gallery forest and on agronomic *** forest native species,Enterolobium contortisiliquum（Vell.） Morong and Sapindus saponaria L.,and two agronomic species（these as control）,Oryza sativa *** Solanum lycopersicum *** used in the lab and greenhouse assays with seeds and leaf extracts of *** species were more affected than native species when co-germinated with seeds of *** germination percentage and speed germination index of the agronomic species were reduced in both in vitro and greenhouse *** the same assays,the seeds of native species showed no significant differences in the parameters ***,the initial growth of the four species assayed was affected,with reduction in plant length and shoot diameter followed by significant reduction in plantlet shoot and root *** the assays with irrigation of *** leaf extracts,no significant inhibitory effects on germination were observed for all *** and shoot diameter of the native species were not affected by the leaf extracts,nor were fresh and dry ***,these parameters increased in the agronomic species as they were irrigated with leaf *** on our data we conclude that seed leachates of *** affect germination and seedling development of other species,suggesting that its invasive behavior is due mainly to seed *** with less pronounced effects on native species,allelopathy of *** might also influence Interspecific competition in its natural environment.

关键词： Allelochemicals Allelopathy Catechin Fabaceae Gallery forest

Opportunities for Remote Collaboration in a Social Web Search Model That Integrates Parents and Children

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Social Networking 2014年第2期3卷 127-133页

作者： Sandra regina Rocha Silva geraldo Bonorino Xexéo Moacir Florentino da Silva Jr. Alberto Luiz Coimbra Institute for Graduate Studies and Research in Engineering Federal University of Rio de Janeiro (UFRJ) Rio de Janeiro Brazil Instituto Federal de Ciência e Tecnologia do Maranhao (IFMA) Maranhao Brazil

Traditionally, search engines are designed to support a single user working alone. However, the construction of knowledge is enriched when one adds collaboration to search tasks. We identified opportunities for remote collaboration in a Social Web search model that integrates parents and children guided by 5W + 1H (who, what, where, when, why, how) dimensions. Our social search model aims at improving the search process for children. We found 7 opportunities for remote collaboration on the search process, based on implicit-explicit interactions.

关键词： Social Search Collaborative Information Retrieval Collaborative Information Seeking Opportunities for Collaboration Child

In vitro activity of neem oil [Azadirachta indica A. Juss (Meliaceae)] on Aspergillus flavus growth, sporulation, viability of spores, morphology and Aflatoxins B1 and B2 production

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Advances in Bioscience and Biotechnology 2010年第4期1卷 292-299页

作者： Christiane L. da Costa marcia R. F. geraldo Carla C. Arrotéia Carlos Kemmelmeier 不详

The effectiveness of neem (Azadiracta indica) oil on the growth, morphology, sporulation, viability of spores, aflatoxin B1 and B2 production by A. flavus on Yeast Extract-Sucrose medium was determined. Neem oil inhibited the fungal growth (i.e. mycelia dry weight, diameter of colony and growth rate) on solid media at concentrations from 0.5 to 5.0% v/v, although it significantly increased sporulation in the same conditions. Spores obtained from cultures grown without neem oil reduced germination when incubated in a neem oil supplemented medium. Colonies grown on solid media and in submerged cultures in the presence of neem oil exhibited morphological alterations, including granular cytoplasm, atypical hyphae branching pattern, abnormal and undifferentiated conidiophores. High Performance Liquid Chromatography was used to measure aflatoxins. In submerged cultures, neem oil at concentrations from 0.5 to 4.0% v/v caused approximately 95% inhibition in Aflatoxin B1 and B2. On other hand, these conditions failed to suppress fungal growth. Current research emphasized that neem oil was not fungistatic or fungicidal, but exhibited anti-aflatoxigenic activity.

关键词： Azadirachta indica Aspergillus flavus Neem oil Aflatoxins

Initial Growth of Eucalyptus with Different Spatial Arrangements in Agrosilvopastoral Systems

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American Journal of Plant Sciences 2017年第6期8卷 1296-1303页

作者： Marina Alves Clemente Marcos Vieira de Faria regina Maria Quintão Lana Jose geraldo Mageste Carlos Juliano Brant Albuquerque Department of Agronomy Federal University of Uberl&#226ndia–UF Uberl&#226ndia Brazil Agricultural Research Company of Minas Gerais–EPAMIG Uberaba Brazil

Success of integrating livestock farming with forestry systems or SAF′s (Agroforestry Systems) highly depends on correct chose of the tree component and the best spatial arrangement of plants, for which eucalyptus has proven as an excellent option. Therefore, the objective of this study was to evaluate eucalyptus wood yield under different spatial arrangements in agrosilvipastoral system. The arrangements were: single rows 10 × 2 m, double rows (2 × 3) + 15 m and (2 × 3) + 20 m and triple rows (3 × 2 × 3) +20 m. Silvicultural evaluations (DBH, tree height, tree volume and volume per hectare) were done eighteen months after experiment installation. The experimental design was randomized blocks with six repetitions and two trees per plot. Trees were arbitrarily identified in each spatial arrangement, numbered from 1 to 5, totaling 30 plots in each system. The DBH increased as the alleys became closer to each other, being higher in the10 × 2 m and (2 × 3) + 15 m systems;tree height increased in denser spacing—10 × 2 m, (2 × 3) + 15 m and (3 × 2 × 3) + 20 m;the volume of wood per plant and per hectare showed higher values in the 10 × 2 m and (2 × 3) + 15 m systems. The lowest yield was found in the system with the least amount of trees, i.e. (2 × 3) + 20 m (576 trees/ha).

关键词： ASPS Productivity Sustainability Agrosilvipastoral System

Therapeutic and biological activities of Calotropis procera(Ait.) ***.

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Asian Pacific Journal of Tropical Medicine 2010年第4期3卷 332-336页

作者： marcia Calheiros Chaves Silva Antonio Batista da Silva Fabiano Moura Teixeira Paulo Cesar Pereira de Sousa regina Maria Macedo Rondon Jose Eduardo Ribeiro Honorio Junior Luiz Rafael Leite Sampaio Samanda Lima Oliveira Angela Nadyla Martins Holonda Silvania Maria Mendes de Vasconcelos Enfermeira Mestre em Farmacologia/Universidade Federal do Ceara/UFC Farmaceutico Mestre em Patologia Tropical/Universidade Federal do Amazonas/UFAM Biologo Mestre em Bioquimica/Universidade Federal do Ceara/UFC Farmaceutico Mestre em Ciencias Farmaceutica/Universidade Federal do Ceara/UFC Biologa Mestre em Producao Animal/Universidade Estadual do Ceara/UECE Biologo Mestre em Fisiologia da Universidade Estadual do Ceara/UECE Enfermeiro Mestrando em Farmacologia da Universidade Federal do Ceara/UFC Aluna de Farmacia da Universidade Federal do Ceara/UFC Enfermeira Professora Adjunto do Depto.de Fisiologia e Farmacologia da Universidade Federal do Ceara/UFC

Medicinal plants have been used to treat various ailments of the poor population around the world;hence the interest among researchers to know the active ingredients of certain plants has being *** Calotropis procera(***) is a plant original from Africa,commonly found in northeastern *** is well known for their pharmacological properties,since it produces large amounts of *** important role that medicinal plants play in folk medicine has led us to develop this article in order to review the major pharmacological activities of C. procera.

关键词： Calotropis procera Pharmacological activity Medicinal plants