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Concerns about the application of resistance exercise with blood-flow restriction and thrombosis risk in hemodialysis patients

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Journal of Sport and Health Science 2024年第4期13卷 548-558,F0003页

作者： Hugo de Luca Correa Lysleine Alves Deus Dahan da Cunha Nascimento Nicholas Rolnick Rodrigo Vanerson Passos Neves Andrea Lucena Reis Thais Branquinho de Araujo Carmen Tzanno-martins Fernanda Silveira Tavares Luiz Sinesio Silva neto Claudio Avelino Rodrigues Santos Paolo Lucas Rodrigues-Silva Fernando Honorato Souza Vitoria Marra da Motta Vilalva Mestrinho Rafael Lavarini dos Santos Rosangela Vieira Andrade Jonato Prestes Thiago dos Santos Rosa Post-graduate Program of Physical Education Catholic University of BrasıliaBrasılia 71966-700Brazil The Human Performance Mechanic Lehman CollegeNew YorkNY 10011USA Clinical Group Home Dialysis Center and RenalClass Sao Paulo 01239-040Brazil Department of Medicine Catholic University of BrasıliaBrasılia 71966-700Brazil Faculty of Medicine Federal University of TocantinsTocantins 77001-090Brazil Embrapa Genetic Resources and Biotechnology Brasılia 70770-917Brazil Graduate Program of Genomic Sciences and Biotechnology Brasılia 71966-700Brazil

Background:Hemodialysis(HD) per se is a risk factor for *** the growing body of evidence on blood-flow restriction(BFR) exercise in HD patients,identification of possible risk factors related to the prothrombotic agent D-dimer is required for the safety and feasibility of this training *** aim of the present study was to identify risk factors associated with higher D-dimer levels and to determine the acute effect of resistance exercise(RE) with BFR on this ***:Two hundred and six HD patients volunteered for this study(all with a glomerular filtration rate of 70 years old),and HD ***,RE+BFR significantly increases D-dimer after 4 *** with borderline baseline D-dimer levels(400-490 ng/mL) displayed increased risk of elevating D-dimer over the normal range(≥500 ng/mL).Conclusion:These results identified factors associated with a heightened prothrombotic state and may assist in the screening process for HD patients who wish to undergo RE+BFR.D-dimer and/or other fibrinolysis factors should be assessed at baseline and throughout the protocol as a precautionary measure to maximize safety during RE+BFR.

关键词： Blood-flow restriction Chronic kidney disease Coagulation Hemodialysis Vascular occlusion exercises

Response to Commentary by Dr. Matthew J. Clarkson on

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Journal of Sport and Health Science 2024年第5期13卷 670-671页

作者： Hugo de Luca Corrêa Lysleine Alves Deus Dahan da Cunha Nascimento Nicholas Rolnick Rodrigo Vanerson Passos Neves Andrea Lucena Reis Thais Branquinho de Araújo Carmen Tzanno-martins Fernanda Silveira Tavares Luiz Sinésio Silva neto Cláudio Avelino Rodrigues Santos Paolo Lucas Rodrigues-Silva Fernando Honorato Souza Vitória Marra da Motta Vilalva Mestrinho Rafael Lavarini dos Santos Rosangela Vieira Andrade Jonato Prestes Thiago dos Santos Rosa Post-graduate Program of Physical Education Catholic University of BrasıliaBrasılia 71966-700Brazil The Human Performance Mechanic Lehman CollegeNew YorkNY 10011USA Clinical Group Home Dialysis Center and RenalClass Sao Paulo 01239-040Brazil Department of Medicine Catholic University of BrasıliaBrasılia 71966-700Brazil Faculty of Medicine Federal University of TocantinsTocantins 77001-090Brazil Embrapa Genetic Resources and Biotechnology Brasılia 70770-917Brazil g Graduate Program of Genomic Sciences and Biotechnology Brasılia 71966-700Brazil

Dear editor:We sincerely thank Matthew *** for his insightful commentary1 on our recent publication in the Journal of Sport and Health Science.2 Clarkson's pioneering work in the development and application of blood flow restriction (BFR) exercise protocols has undeniably laid the groundwork for subsequent investigations in this field,including our own.(3-6)His commentary not only highlights the relevance and timeliness of our study but also offers valuable perspectives on refining safety considerations for intradialytic BFR exercise among hemodialysis patients.

关键词： patients application flow

Flight performance and wing morphology in the bat Carollia perspicillata:biophysical models and energetics

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Integrative Zoology 2023年第5期18卷 876-890页

作者： Lucas de Oliveira CARNEIRO Breno MELLADO marcelo Rodrigues NOGUEIRA Ariovaldo Pereira da CRUZ-neto Leandro Rabello MONTEIRO Laboratório de Ciências Ambientais Centro de Biociências e BiotecnologiaUniversidade Estadual do Norte FluminenseCampos dos GoytacazesRio de JaneiroBrasil Departamento de Biodiversidade Universidade Estadual PaulistaRio ClaroSão PauloBrasil

Studies on functional performance are important to understand the processes responsible for the evolution of *** trait variation within species influences the energetic cost of locomotion and impacts life history traits,with ecological and evolutionary *** study examined wing morphology correlates of flight performance measured by energetic expenditure in the Seba’s short-tailed bat,Carollia *** the flight experiments,nature caught bats(59 females,57 males)were allowed to fly for 3 min in a *** each flight,thermographic images were taken to measure body temperature,and biophysical models were used to calculate sensible heat loss as a measure of energetic *** morphological traits were measured for each individual and associated with heat loss and power required to fly on performance *** morphological traits explained 7-10%of flight energetic cost,and morphologies with the best performance would save the energy equivalent to 9-30%of total daily *** optimal performance areas within the *** morphospace were consistent with predicted selection trends from the literature.A trade-off between demands for flight speed and maneuverability was *** loading and camber presented sexual *** morphological differences are likely associated with more economical but less maneuverable flight in females,leading them to fly more often in open areas along the forest *** findings demonstrate how small scale changes in wing morphology can affect life history strategies and fitness.

关键词： aerodynamics Chiroptera infrared thermography performance surfaces Phyllostomidae wing morphometrics

Species richness and similarity of the flora on four lajedos in Boa Nova, Bahia, Brazil

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Journal of Mountain Science 2023年第6期20卷 1526-1539页

作者： Morgana Maria DO CARMO BARBOSA Anderson FERREIRA PINTO MACHADO Andrea Karla ALMEIDA DOS SANTOS Raymundo JoséDE Sá-neto Michele martins CORRêA Graduate Program in Environmental Sciences State University of Southwest BahiaUniversity Campus“Juvino Oliveira”BR 415km 0445700-000ItapetingaBahiaBrazil Secretary of Education of the State of Bahia Military Police College Eraldo TinocoBrasilia Avenue273Kadija45650-120Vitoria da ConquistaBahiaBrazil Mongoyós Herbarium Multidisciplinary Institute in HealthCampus Anísio TeixeiraFederal University of BahiaRua Hormindo Barros58Bairro Candeias45029-094Vitoria da ConquistaBahiaBrazil Department of Natural Sciences State University of Southwest BahiaEstrada do Bem Querers/nBairro Candeias45083-900Vitoria da ConquistaBahiaBrazil

The municipality of Boa Nova,in northeastern Brazil,is in an ecotone zone between the Caatinga and Atlantic Forest phytogeographic *** transition phytophysiognomy is seasonal forest and known locally as mata de cipó.In these phytophysiognomies there are lajedos,which are rock outcrops colonized by vegetation welladapted to extreme microclimatic variation and vegetation diversity is affected by the vegetation types of the surrounding *** to the singularity of these environments and the relevance of floristic studies for conservation,this work aimed to identify the species richness and compare the similarity of the flora on four rock outcrops in Boa *** flora was surveyed during exploratory walks along lajedos between 2016 and *** total,162 species were identified on the Boa Nova *** flora has a composition and structure similar to semiarid outcrops,as well as endemic species that also occur in surrounding *** the proximity,a similarity index revealed there is floristic dissimilarity between the *** new occurrences were recorded for the region,five species are threatened with extinction(Aosa gilgiana,Ficus cyclophylla,Hippeastrum stigmovittatum,Pleroma caatingae and Trixis pruskii),and 43 species are common in anthropogenic *** reinforces the importance of actions to conserve these areas.

关键词： Ecotone Flora Inselberg Rock outcrops Semiarid Similarity

Acute kidney injury and electrolyte disorders in COVID-19

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World Journal of Virology 2022年第5期11卷 283-292页

作者： Gabriel martins Nogueira Noel Lucas Oliveira Rodrigues Silva Ana Flávia Moura marcelo Augusto Duarte Silveira JoséA Moura-neto Department of Medicine Bahiana School of Medicine and Public HealthSalvador 40290-000BahiaBrazil Department of Nephrology D’Or Institute for Research and EducationHospital São RafaelSalvador 41253900BahiaBrazil

Acute kidney injury(AKI)and electrolyte disorders are important complications of hospitalized coronavirus disease 2019(COVID-19)*** is thought to occur due to multiple pathophysiological mechanisms,such as multiple organ dysfunction(mainly cardiac and respiratory),direct viral entry in the renal tubules,and cytokine release *** is present in approximately one in every ten hospitalized COVID-19 *** incidence rates of AKI increase in patients who are admitted to the intensive care unit(ICU),with levels higher than 50%.Additionally,renal replacement therapy(RRT)is used in 7%of all AKI cases,but in nearly 20%of patients admitted to an ***-19 patients with AKI are considered moderate-to-severe cases and are managed with multiple interdisciplinary *** acts as a risk factor for mortality in severe acute respiratory syndrome coronavirus 2 infection,especially when RRT is *** disorders are also common manifestations in hospitalized COVID-19 patients,mainly hyponatremia,hypokalemia,and *** occurs due to a combination of syndrome of inappropriate secretion of antidiuretic hormone and gastrointestinal fluid loss from vomiting and *** it comes to hypokalemia,its mechanism is not fully understood but may derive from hyperaldosteronism due to renin angiotensin aldosterone system overstimulation and gastrointestinal fluid loss as *** clinical features of hypokalemia in COVID-19 are similar to those in other *** is the most common electrolyte disorder in COVID-19 and seems to occur because of vitamin D deficiency and parathyroid *** is also highly associated with longer hospital and ICU stay.

关键词： COVID-19 SARS-CoV-2 Acute kidney injury Electrolyte disorders Renal dialysis

The evolution of available pharmacological treatments for variceal bleeding secondary to portal hypertension: A scope review

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iLIVER 2023年第3期2卷 170-176页

作者： Eduarda Raisa Coser Raphael Bernardo neto Izabel Cristina Meister martins Coelho Norma Possa Marroni Claudio Augusto Marroni Camila Moraes Marques Faculdades Pequeno Principe Brazil Universidade Federal de Ciencias da Saude de Porto Alegre Brazil

The texts analyzed in full totaled 110,of which 36 articles published between 2001 and 2020 were selected,with quantitative approaches,case reviews,liter-ature reviews,meta-analyses,and *** is concluded that beta-blockers are the drugs of choice for primary prophylaxis of variceal *** for secondary prophylaxis,there is an association of these with nitrates and endoscopic *** regard to acute bleeding,the use of vasoactive drugs is chosen,especially ***,it is important to emphasize that there is a shortage of clinical studies and a need for investment in new therapies.

关键词： Portal hypertension Clinical treatment pharmacology and variceal bleeding

Follicular dendritic cell sarcoma of the liver:unusual presentation of a rare tumor and literature review

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Hepatobiliary & Pancreatic Diseases International 2011年第4期10卷 443-445页

作者： Paulo N martins Sanjay Reddy Ann-Britt martins marcelo Facciuto Department of Surgery Division of Hepatobiliary Surgery and TransplantationNew York Medical CollegeNew YorkUSA Department of Surgery New York Medical CollegeSt.Vincent's Catholic Medical CenterNew YorkUSA

BACKGROUND:Hepatic follicular dendritic cell (FDC) sarcoma is an extremely rare *** commonly,FDC sarcoma presents as a solitary mass in lymph nodes,however,several extra-nodal locations have been ***:We report a case of a 53-year-old female who presented with symptoms of abdominal pain,fever,anemia,and *** an extensive review of the literature,we have found only 12 cases of hepatic FDC ***:The tumor was 11.5 cm in diameter and composed of spindle and epithelioid cells with ovoid nuclei and associated with mixed inflammatory *** stains were positive for CD35 and *** patient underwent a left hepatic ***:Liver follicular dendritic cell sarcoma is a very rare *** cases present with abdominal pain and weight loss,and most of them can be managed by hepatic resection with excellent short-term outcomes.

关键词： follicular dendritic cell tumor liver neoplasms sarcoma jaundice

Xanthogranulomatous cholecystitis mimicking gallbladder cancer and causing obstructive cholestasis

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Hepatobiliary & Pancreatic Diseases International 2012年第5期11卷 549-552页

作者： Paulo N martins Patricia Sheiner marcelo Facciuto Department of Surgery Transplant DivisionMassachusetts General HospitalHarvard Medical School Department of Surgery Division of Hepatobiliary Surgery and TransplantationNew York Medical College Division of Transplantation Mount Sinai Hospital

BACKGROUND: Xanthogranulomatous cholecystitis (XGC) is a destructive inflammatory disease of the gallbladder that can mimic gallbladder carcinoma. METHODS: We present the case of a 35-year-old Hispanic male complaining of right upper quadrant pain and jaundice for 2 months prior to admission. He denied a history of fever, nausea/ vomiting, and weight loss. The past medical history was relevant only for diabetes. He had no previous history of jaundice or previous operations. RESULTS: CA19-9 was slightly elevated (52 U/mL). Abdominal ultrasonography showed an irregular thickening of the gallbladder wall and no gallstones were detected. CT scan also revealed an irregular thickening of the wall of the gallbladder body suggestive of malignancy. At laparotomy, the mass was adherent to the duodenum and colon, and although the frozen section biopsy was negative, the intraoperative findings were suggestive of malignancy, and the patient underwent left liver trisegmentectomy, resection of the common bile duct and Roux-en-Y hepaticojejunostomy. Pathological examination unexpectedly revealed XGC without malignancy. CONCLUSIONS: Preoperative and intraoperative differential diagnosis of XGC from gallbladder carcinoma remains a challenge when it is associated with inflammatory involvement of surrounding tissues. Since gallbladder carcinoma and XGC may coexist, radical resection is justified when malignancy cannot be completely ruled out.

关键词： xanthogranulomatous cholecystitis gallbladder cancer obstructive cholestasis

Indian medicinal plants are effective in the treatment and management of COVID-19

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BIOCELL 2023年第4期47卷 677-695页

作者： SUBHASH CHANDRA SANTWANA PALAI EDINARDO FAGNER FERREIRA-MATIAS IVO CAVALCANTE PITA-neto CÍCERO LUCAS GOMES-RAMALHO EDLANE martins DE ANDRADE RAY SILVA DE ALMEIDA MARCELLO IRITI HENRIQUE DOUGLAS MELO-COUTINHO Department of Pharmaceutical Chemistry SGRR UniversityUttarakhand248001India Department of Pharmaceutical Chemistry HNB Garhwal UniversitySrinagar246174India Department of Veterinary Pharmacology&Toxicology College of Veterinary Science and Animal HusbandryBhubaneswar751003India CECAPE—College of Dentistry Juazeiro do Norte63050-203Brazil Department of Biological Chemistry Regional University of CaririCrato63105-000Brazil Department of Biomedical Surgical and Dental SciencesUniversitàdegli Studi di MilanoMilan20133Italy National Interuniversity Consortium of Materials Science and Technology Florence50121Italy

Indian medicinal plants are referred to as the“nectar of life”owing to their phytochemicals and bioactive complexes that are beneficial in treating *** disease 2019(COVID-19)is a global health issue without any proper *** indigenous plants of India can be exploited to control the precise signs of *** Ministry of AYUSH(Ayurveda,Yoga and Naturopathy,Unani,Siddha,and Homeopathy)has advised routine usage of medicinal plants for *** plants like Zingiber officinalis,Azadirachta indica,Ocimum sanctum,Nigella sativa,Withania somnifera,Curcuma longa,Piper nigrum,Allium sativum,Tinospora cordifolia,*** immunity-boosting,antiviral,antibacterial,antioxidant and anti-inflammatory actions that can suppress and treat symptoms of *** vitro,in vivo as well as in silico validation,these phytochemicals can help us to manage and treat COVID-19 *** integration of traditional knowledge in the prophylaxis of corona infection and current skills validating it for the development of precise and powerful therapeutic approaches will more efficiently resolve different clinical aspects of *** review focuses on both traditional and emergent methods to prevent and treat COVID-19 with various Indian medicinal plants along with their phytochemicals.

关键词： Antiviral Corona virus Diagnosis Immunity Herbs