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Indications and results of renal biopsy in children:a 36-year experience

World Journal of Pediatrics 2018年第2期14卷 127-133页

作者： Luisa Santangelo Giuseppe Stefano Netti Paolo Giordano Vincenza Carbone Marida martino diletta Domenica Torres Michele Rossini Anna Maria di Palma Loreto Gesualdo Mario Giordano Unit of Pediatric Nephrology and dialysis Pediatric Hospital"GiovanniⅩⅩⅢ"BariItaly Clinical Pathology Department of Medical and Surgical SciencesUniversity of FoggiaFoggiaItaly Unit of Nephrology Dialysis and TransplantationDepartment of Emergency and OrganTransplantationUniversity"Aldo Moro"BariItaly

Background This study was conducted to investigate retrospectively the indications for renal biopsy(RB)in native kidneys and to analyze pathological findings in a single tertiary pediatric hospital in Southern Italy for the last 36 *** All patients who underwent RB at our hospital from 1979 to 2014 were *** renal tissue specimens were studied under light and immunofluorescent microscopy,while electron microscopy was performed only for specific clinical *** The study group included 213 patients(female 43.2%)who underwent 225 percutaneous native kidney *** age was 10.4 years(range 0.6-24 years).The most frequent indication for RB was nephrotic syndrome(44.4%),fol-lowed by proteinuria(27.6%),asymptomatic hematuria(17.3%)and acute kidney injury(9.8%).Gross hematuria appeared after biopsy in less than 5%of the patients,but none of them needed blood *** renal tissue sample was obtained in 95.5%of the renal *** glomerulonephritis(GN)was the most common finding(61.4%),followed by secondary GN(21.4%),tubulointerstitial diseases(3.7%)and hereditary nephropathy(2.8%),while in 10.7%of the cases,normal renal tissues were *** to histopathological diagnosis,the most common causes of primary GN were IgA nephropathy(20.9%),followed by minimal change disease(18.1%)and focal segmental glomerulosclerosis(11.6%).Conclusions The epidemiology of glomerular disease in our single-center cohort is similar to that shown in other national and international ***,our study shows that percutaneous ultrasound-guided RB is a safe,reliable and effec-tive technique in children.

关键词： Epidemiology Glomerular diseases Nephropathy Pediatric patients Renal biopsy

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Surgical management of genital lymphoedema:experience and critical considerations from a tricenter study

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Plastic and Aesthetic Research 2023年第1期10卷 629-642页

作者： martino Guiotto Michele Maruccia Rossella Elia Marco Fresa Lidia Molinari Marie Nicod Lalonde Corrado Campisi Pietro Giovanni di Summa Department of Plastic and Hand Surgery Centre Hospitalier Universitaire Vaudois(CHUV)Lausanne 1011Switzerland Department of Plastic Surgery Bari University HospitalBari 70124Italy Angiology Department Centre Hospitalier Universitaire Vaudois(CHUV)Lausanne 1011Switzerland Department of Plastic Surgery Lymphatic UnitSan Martino HospitalGenova 16132Italy Nuclear Medicine and Molecular Imaging Centre Hospitalier Universitaire Vaudois(CHUV)Lausanne 1011Switzerland

Aim:Genital lymphoedema(GL)is a chronic and debilitating disease,which can severely affect the patient’s quality of life with significant socio-economic ***,no gold standard algorithm exists for GL from diagnosis to *** study proposes our therapeutic flowchart based on the three senior consultants’experience in lymphatic ***:A retrospective investigation was conducted on a prospectively maintained database(2018-2022).Inclusion criteria involved all patients who underwent surgical procedures for treating GL in three plastic surgery departments(Lausanne,Bari,and Genova).Outcomes were assessed in terms of oedema reduction,stage regression,and functional reported ***:16 patients with GL were included:50%underwent debulking surgery,18.8%microsurgery,and 31.2%debulking+*** recorded a significant regression of the GL stage:62.5%shifted from stage II/III to postoperative stage ***,we found an infection recurrency resolution in 50%,a scrotal oedema reduction in 62.5%,and a scrotal oedema resolution in 37.5%of the patients *** almost half of the patients(53.3%)with associated penile oedema described persistent postoperative penile oedema,only two patients complained of persistent ***:According to our clinical experience,preoperative and postoperative physical functional therapy is always *** stages I and IIA,after the failure of the conservative treatment,lymph-venous shunts and lymph node transplantation surgery are proposed at the early *** GL is already diagnosed at stages IIB and III,the debulking surgery,together with functional procedures,represents our first approach.

关键词： Genital lymphoedema debulking surgery functional surgery microsurgery lymphatic venous anastomosis multi lymphatic-venous anastomoses lymph node transplantation

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2011—2020年广州市肺结核死亡趋势及年龄-时期-队列模型分析

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中国防痨杂志 2025年第1期47卷 44-50页

作者：李雪秋刘群唐科吴迪广州市胸科医院结核病防治所一分所广州510095 广东省生物制品与药物研究所药理研究室广州510440 广州市疾病预防控制中心慢性非传染性疾病预防控制部广州510440 广东医科大学公共卫生学院东莞523808

目的:分析2011—2020年广州市肺结核患者的死亡情况和死亡率变化趋势,为制定防控策略和措施提供科学依据。方法:采用Joinpoint回归模型分析2011—2020年广州市全年龄段人群肺结核死亡率变化趋势,并计算年度变化百分比(annual percent ch... 详细信息

目的:分析2011—2020年广州市肺结核患者的死亡情况和死亡率变化趋势,为制定防控策略和措施提供科学依据。方法:采用Joinpoint回归模型分析2011—2020年广州市全年龄段人群肺结核死亡率变化趋势,并计算年度变化百分比(annual percent change,APC)和平均年度变化百分比(average annual percent change,AAPC);使用年龄-时期-队列模型分析广州市20~85岁人群肺结核死亡风险的年龄、时期和队列效应。结果:广州市2011—2020年报告肺结核死亡患者2144例,年均报告标化死亡率为2.57/10万;男性肺结核标化死亡率为4.19/10万,约为女性标化死亡率(0.96/10万)的4.4倍。10年间广州市肺结核年龄标化死亡率总体呈现下降趋势,AAPC为-4.15%(95%CI:-6.41%~-1.85%,P=0.003);其中,女性肺结核死亡率下降速度高于男性,AAPC分别为-6.72%(95%CI:-10.38%~-2.92%,P=0.004)和-3.55%(95%CI:-6.19%~-0.85%,P=0.017)。在不同年龄段人群中,0~49岁和≥65岁年龄段人群肺结核死亡率均呈现明显下降趋势,AAPC分别为-7.05%(95%CI:-11.52%~-2.34%,P=0.009)和-3.94%(95%CI:-6.22%~-1.62%,P=0.005)。年龄-时期-队列模型的年龄效应显示,随着年龄的增长,肺结核死亡风险不断上升,≥65岁人群尤为显著,发病率由66~67岁年龄组的2.93/10万增长至84~85岁年龄组的6.10/10万。时期效应显示,肺结核死亡风险随着时期的变化总体呈现下降趋势,相对危险度(risk ratio,RR)从2011—2012年时期组的1.35下降至2019—2020年时期组的0.81。队列效应显示,越晚出生的人群肺结核死亡风险越低,RR值从1926—1927年出生队列的5.91降低至1998—1999年出生队列的0.16。结论:广州市肺结核死亡率总体呈不断下降的趋势,但男性和女性肺结核死亡率差距较大。需重点关注男性和≥65岁年龄段的老年人群,并实施针对性的防控和治疗措施。

关键词：结核,肺死亡率回归分析队列研究

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GUE via Frobenius *** Matrix Gravity to Topological Gravity and Back

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Acta Mathematica Sinica,English Series 2024年第1期40卷 383-405页

作者： di YANG School of Mathematical Sciences University of Science and Technology of ChinaHefei 230026P.R.China

Dubrovin establishes a certain relationship between the GUE partition function and the partition function of Gromov-Witten invariants of the complex projective *** this paper,we give a direct proof of Dubrovin’s *** ... 详细信息

关键词： Frobenius manifold Dubrovin-Zhang hierarchy GUE Toda lattice hierarchy jet space topological gravity matrix gravity

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Ultrathin Wood Laminae–Thermoplastic Starch Biodegradable Composites

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Journal of Renewable Materials 2018年第5期6卷 493-503页

作者： Andrea Dorigato martino Negri Alessandro Pegoretti University of Trento Department of Industrial Engineering and INSTM Research UnitVia Sommarive 938123 TrentoItaly Trees&Timber Institute CNR IVALSAI-38010 San Michele all’AdigeTrentoItaly

Novel fully biodegradable thermoplastic composite laminates reinforced with ultrathin wood laminae were prepared through a hot-pressing process by using two different thermoplastic starch(TPS)*** microstructure and physical properties of the resulting unidirectional and bidirectional laminates were *** investigated materials presented a complex microstructure,in which the porosity of the wood laminae was almost entirely occluded by the polymer *** mechanical behavior of the laminates was strongly affected by the obtained microstructure,and matrix penetration in wood pores led to biodegradable composites with elastic modulus and tensile strength higher than those of their ***,thermal welding and thermoformability tests proved how these materials possess features typical of thermoplastic materials.

关键词： Starch ultrathin wood laminae composites mechanical properties

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Preparation and Characterization of Fe-Based Metallic Glasses with Pure and Raw Elements

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Chinese Physics Letters 2012年第11期29卷 207-210页

作者： Nassima Seghairi Badis Bendjemil Gabriel Lavorato Alberto Castellero marcello Baricco dipartimento di Chimica I.F.M/NIS/CNISM/INSTM Universitàdi TorinoVia Giuria 910125 TrinoItaly University of Larbi Ben M'hidi Oum El BouaghiAlgeria LASEA Faculty of SciencesDepartment of ChimistryUniversity of AnnabaAlgeria University of Guelma P.O.Box 1224000 GuelmaAlgeria

Amorphous alloys with a composition(at.%)Fe_(48)Cr_(15)Mo_(14)C_(15)B_(6)Y_(2) were prepared by using either pure elements(alloy B1)or a commercial AISI430 steel as a base material(B2).When prepared from pure elements,alloy(B1)could be cast in plate form with a fixed thickness of 2 mm and variable lengths between 10 and 20 mm by means of copper-mold injection in an air *** the case of alloy B2,prepared by using commercial grade raw materials,rods of 2 mm diameter are ***(B1 and B2)of width 5 mm and thickness about 30μm are prepared from the arc-melted ingots using a single roller melt spinner at a wheel speed of 40 m/*** thermal and structural properties of the samples are measured by a combination of differential scanning calorimetry(DSC),x-ray diffraction and scanning electron *** compositions are checked by energy dispersive spectroscopy analysis.X-ray diffraction and scanning electron microscopy observations confirm that an amorphous structure is obtained in all the samples.A minor fraction of crystalline phases(oxides and carbides)is detected on the as-cast *** of hardness and Young modulus were measured by nanoindentation for both the *** effects of adverse casting conditions(such as air atmosphere,non-conventional injection copper mold casting and the partial replacement of pure elements with commercial grade raw materials)on the glass formation and properties of the alloy are discussed.

关键词： alloy casting roller

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Embedded fuzzing:a review of challenges,tools,and solutions

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Cybersecurity 2022年第4期5卷 1-18页

作者： Max Eisele marcello Maugeri Rachna Shriwas Christopher Huth Giampaolo Bella Safety Security and PrivacyRobert Bosch GmbHRenningenGermany Dept.of Math and Computer Science Universita degli Studi di CataniaCataniaItaly RBEl Robert Bosch GmbHBangaloreIndia.

Fuzzing has become one of the best-established methods to uncover software ***,the market of embedded systems,which binds the software execution tightly to the very hardware architecture,has grown at a steady pace,and that pace is anticipated to become yet more sustained in the near *** systems also beneft from fuzzing,but the innumerable existing architectures and hardware peripherals complicate the development of general and usable approaches,hence a plethora of tools have recently *** comes a stringent need for a systematic review in the area of fuzzing approaches for embedded systems,which we term'embedded fuzzing"for *** inclusion criteria chosen in this article are semi-objective in their coverage of the most relevant publication venues as well as of our personal *** review rests on a formal definition we develop to represent the realm of embedded *** continues by discussing the approaches that satisfy the inclusion criteria,then defines the relevant elements of comparison and groups the approaches according to how the execution environment is served to the system under *** resulting review produces a table with 42 entries,which in turn supports discussion suggesting vast room for future research due to the limitations noted.

关键词： Embedded systems Dynamic analysis Vulnerability mining Embedded security Software security

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Numerical simulation of dynamic characteristics of a cable-stayed aqueduct bridge

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Earthquake Engineering and Engineering Vibration 2011年第4期10卷 569-579页

作者： LiYuchun di Qingshuang Department of Hydraulic Engineering Tongji University Shanghai 200092 China Research Institute of Structural Engineering and disaster Reduction Tongji University Shanghai 200092 China

In this paper, a full-scale 3-D finite element model of the Jundushan cable-stayed aqueduct bridge is established with ANSYS Code. The shell, fluid, tension-only spar and beam elements are used for modeling the aqueduct deck, filled water, cables and support towers, respectively. A multi-element cable formulation is introduced to simulate the cable vibration. The dry （without water） and wet （with water） modes of the aqueduct bridge are both extracted and investigated in detail. The dry modes of the aqueduct bridge are basically similar to those of highway cable-stayed bridges. A dry mode may correspond to two types of wet modes, which are called the in-phase （with lower frequency） and out-of-phase （with higher frequency） modes. When the water-structure system vibrates in the in-phase/out-of-phase modes, the aqueduct deck moves and water sloshes in the same/opposite phase-angle, and the sloshing water may take different surface-wave modes. The wet modes of the system reflect the properties of interaction among the deck, towers, cables and water. The in-phase wet frequency generally decreases as the water depth increases, and the out-of-phase wet frequency may increase or decrease as the water depth increases.

关键词： cable-stayed aqueduct bridge dynamic characteristics fluid-structure interaction numerical simulation

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Liquid suspensions of single and binary component solid particles-An overview

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China Particuology 2007年第5期5卷 312-320页

作者： Renzo di Felice dipartimento di Ingegneria Chimica e di Processo "G.B. Bonino" Università degli Studi di Genovavia Opera Pia1516145 GenovaItaly

In this paper theoretical approaches and experimental findings relative to the hydrodynamics of liquid suspensions of solid particles by liquids are reported and discussed. For the single particle specie systems, advantages and possible faults of well known empirical correlations are discussed. For binary-solid mixture suspensions, experimental evidence are reviewed and approaches capable of successfully describing observed behaviour are reported.

关键词： Sedimentation Fluidization Voidage function Binary-mixture

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Liver involvement in inflammatory bowel disease: What should the clinician know?

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World Journal of Hepatology 2021年第11期13卷 1534-1551页

作者： Giuseppe Losurdo Irene Vita Brescia Chiara Lillo martino Mezzapesa Michele Barone Mariabeatrice Principi Enzo Ierardi Alfredo di Leo Maria Rendina Section of Gastroenterology Department of Emergency and Organ TransplantationUniversity of BariBari 70124Italy

Inflammatory bowel disease(IBD)may show a wide range of extraintestinal *** this context,liver involvement is a focal point for both an adequate management of the disease and its prognosis,due to possible serious *** association between IBD and primary sclerosing cholangitis is the most known *** association is relevant because it implies an increased risk of both colorectal cancer and ***,drugs such as thiopurines or biologic agents can cause drug-induced liver damage;therefore,this event should be considered when planning IBD ***,particular consideration should be given to the evidence that IBD patients may have concomitant chronic viral hepatitis,such as hepatitis B and hepatitis *** immunosuppressive regimens may cause a hepatitis flare or reactivation of a healthy carrier state,therefore careful monitoring of these patients is ***,the spread of obesity has involved even IBD patients,thus increasing the risk of non-alcoholic fatty liver disease,which has already proven to be more common in IBD patients than in the non-IBD *** phenomenon is considered an emerging issue,as it will become the leading cause of liver cirrhosis.

关键词： Inflammatory bowel disease Liver Primary sclerosing cholangitis Viral hepatitis Immunosuppression Non-alcoholic fatty liver disease

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