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Configuration and validation of a novel prostate disease nomogram predicting prostate biopsy outcome:A prospective study correlating clinical indicators among Filipino adult males with elevated PSA level

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Asian Journal of Urology 2015年第2期2卷 114-122页

作者： Michael E.Chua Patrick P.Tanseco Jonathan S.Mendoza Josefino C.Castillo marcelino l.morales jr Saturnino l.luna jr Institute of Urology St.Luke’s Medical Center-Quezon City and Global CityNCRPhilippines Department of Preventive and Community Medicine St.Luke’s College of Medicine-WHQMNCRPhilippines Department of Urology National Kidney and Transplant InstituteQuezon CityNCRPhilippines

Objective:To configure and validate a novel prostate disease nomogram providing prostate biopsy outcome probabilities from a prospective study correlating clinical indicators and diagnostic parameters among Filipino adult male with elevated serum total prostate specific antigen(PSA)***:All men with an elevated serum total PSA underwent initial prostate biopsy at our institution from January 2011 to August 2014 were *** indicators,diagnostic parameters,which include PSA level and PSA-derivatives,were collected as predictive factors for biopsy *** logistic-regression analysis involving a backward elimination selection procedure was used to select independent predictors.A nomogram was developed to calculate the probability of the biopsy *** validation of the nomogram was performed using separate data set from another center for determination of sensitivity and specificity.A receiver-operating characteristic(ROC)curve was used to assess the accuracy in predicting differential biopsy outcome.

关键词： Nomogram Prostate cancer Benign prostatic hyperplasia Prostatitis

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Chitosan Nanoparticles as Biostimulant in lettuce (lactuca sativa l.) Plants

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Phyton-International Journal of Experimental Botany 2024年第4期93卷 777-787页

作者： Silvia C.Ramírez-Rodríguez Pablo Preciado-Rangel marcelino Cabrera-De la Fuente Susana González-morales Hortensia Ortega-Ortiz Tecnológico Nacional de México Instituto Tecnológico de TorreónEjido AnaTorreónCoahuila27170México Departamento de Horticultura Universidad Autónoma Agraria Antonio NarroSaltillo25315México Departamento de Materiales Avanzados Centro de Investigación en Química AplicadaSaltilloCoahuila25294México

Biodegradable nanoparticles such as chitosan nanoparticles (CSNPs) are used in sustainable agriculture since theyavoid damage to the environment;CSNPs have positive effects such as the accumulation of bioactive compoundsand increased productivity in plants. This study aimed to investigate the impact of applying CSNPs on lettuce,specifically focusing on enzymatic activity, bioactive compounds, and yield. The trial was conducted using a completelyrandomized design, incorporating CSNPs: 0, 0.05, 0.1, 0.2, 0.4, and 0.8 mg ml−1. The doses of 0.4 mg ml−1improve yields up to 24.6% increases and 0.1 mg ml−1 of CSNPs increases total phenols by 31.2% and antioxidantcapacity by 34.6%. In addition, when low concentrations of CSNPs (0.05 and 0.1 mg l−1) were applied, anincrease in catalase was determined. The CSNPs represent a good alternative to be used as a biostimulant in sustainableagriculture because they improve the yield and quality of lettuce by increasing the bioactive compounds.

关键词： Biostimulant bioactive compounds enzymatic activity

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The Beneficial Effects of Components of Garlic (Allium sativum l.) in the Poultry Industry

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Food and Nutrition Sciences 2024年第1期15卷 27-57页

作者： Alejandra Meza-Rios Gilberto Velazquez-Juarez Inkar Castellanos-Huerta Rocio Ivette lopez-Roa luis A. Anguiano-Sevilla Xochitl Hernanez-Velasco Xochitl Hernanez-Velasco Saeed El-Ashram Ebtsam Al-Olayan Billy Hargis Guillermo Tellez-Isaias Adelaida Sara Minia Zepeda-morales Departamento de Farmacobiología CUCEI Universidad de Guadalajara Blvd. M. García Barragán Guadalajara México laboratorio de Análisis Fisicoquímicos Externos Departamento de Química CUCEI Universidad de Guadalajara Boulevard Marcelino García Barragán Guadalajara México Center of Excellence for Poultry Science Department of Poultry Science Dale Bumpers College of Agricultural Food and Life Sciences University of Arkansas Cumberland United States laboratorio de Investigación y Desarrollo Farmacéutico Departamento de Farmacobiología CUCEI Universidad de Guadalajara Boulevard Marcelino García Barragán Guadalajara México Departamento de Medicina y Zootecnia de Aves Facultad de Medicina Veterinaria y Zootecnia UNAM Mexico Mexico Zoology Department Faculty of Science Kafrelsheikh University Kafr El-Sheikh Egypt Department of Zoology College of Science King Saud University Riyadh Saudi Arabia laboratorio de Análisis Clínicos y Bacteriológicos (vinculación) Departamento de Farmacobiología CUCEI Universidad de Guadalajara Boulevard Marcelino García Barragán Guadalajara México

Plant-based antimicrobial agents are readily available, cost-effective, and exhibit low toxicity, making them promising alternatives in combatting microbial infections. Among these plants, garlic (Allium sativum) stands out for its traditional medicinal use in effectively combating various microorganisms. In the poultry industry, preventing avian virus and bacterial infections is paramount for chicken husbandry. However, using conventional drugs poses potential risks to human health. Garlic, a widely used Asian plant in traditional medicine for various pathologies, has shown potential as an herbal prophylactic remedy against viral and bacterial infections. Recently, researchers explored garlic and its derivatives as a scientific strategy in veterinary practices for diverse purposes, such as improving poultry production characteristics and acting as antibiotic growth promoters. This comprehensive review delves into garlic and its derivatives as preventive and corrective treatments for viral diseases in laying hens and broilers. The paper highlights their potential effectiveness and safety as a natural means to enhance poultry health and welfare while mitigating the risks associated with conventional drug usage in the food industry.

关键词： Garlic Antiviral Veterinary Chickens Allium sativum

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