Configuration and validation of a novel prostate disease nomogram predicting prostate biopsy outcome:A prospective study correlating clinical indicators among Filipino adult males with elevated PSA level
作者机构：Institute of UrologySt.Luke’s Medical Center-Quezon City and Global CityNCRPhilippines Department of Preventive and Community MedicineSt.Luke’s College of Medicine-WHQMNCRPhilippines Department of UrologyNational Kidney and Transplant InstituteQuezon CityNCRPhilippines
出 版 物：《Asian Journal of Urology》 (亚洲泌尿外科杂志（英文）)
年 卷 期：2015年第2卷第2期
页 面：114-122页
学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学]
基 金：sponsored by the Institution where the study was conducted it was also awarded with research grant from the Philippine Urological Association,Inc
主 题：Nomogram Prostate cancer Benign prostatic hyperplasia Prostatitis
摘 要：Objective:To configure and validate a novel prostate disease nomogram providing prostate biopsy outcome probabilities from a prospective study correlating clinical indicators and diagnostic parameters among Filipino adult male with elevated serum total prostate specific antigen(PSA)***:All men with an elevated serum total PSA underwent initial prostate biopsy at our institution from January 2011 to August 2014 were *** indicators,diagnostic parameters,which include PSA level and PSA-derivatives,were collected as predictive factors for biopsy *** logistic-regression analysis involving a backward elimination selection procedure was used to select independent predictors.A nomogram was developed to calculate the probability of the biopsy *** validation of the nomogram was performed using separate data set from another center for determination of sensitivity and specificity.A receiver-operating characteristic(ROC)curve was used to assess the accuracy in predicting differential biopsy outcome.
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