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Elastomer Composites with Enhanced Ice Grip Based on Renewable Resources

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Materials Sciences and Applications 2018年第4期9卷 412-429页

作者： Nikolai Dishovski Filis Mitkova mara Kandeva Yordan Angelov Ivan Uzunov Milcho Ivanov Dimitar Klissurski University of Chemical Technology and Metallurgy Sofia Bulgaria Ecopolymeric Systems Ltd. Sofia Bulgaria Technical University Sofia Bulgaria Institute of General and Inorganic Chemistry Bulgarian Academy of Sciences Sofia Bulgaria

Slips and falls on icy surfaces can cause serious injuries of people. The primary risk factor for slipping incidents is undoubtedly the decreased friction coefficient between the shoe sole and the ice or snow surface. Nowadays environmental protection has been gaining significance and becoming highly important for the various innovation strategies. In rubber industry the concept of environmental protection is more often associated with the maximum use of elastomers and ingredients from renewable sources in the manufacture of rubber products. The aim of this work is to investigate the possibilities of using elastomers and ingredients from renewable sources—epoxidized natural rubber, silica obtained by rice husks incineration and microcrystalline cellulose—as fillers and rapeseed oil as a process additive in compositions, intended for the manufacture of soles for winter footwear having an increased coefficient of friction to icy surfaces. The tribological tests based on the coefficient of friction evaluated the adhesion of the composites to the icy surfaces at different temperatures. The complex evaluation of developed composites revealed those containing microcrystalline cellulose and biogenic amorphous silica at a 1:1 ratio as the most suitable for making footwear soles because of the best combination of physicо-mechanical properties and coefficient of friction.

关键词： Elastomer Composite Epoxidized Natural Rubber Biogenic Amorphous Silica Microcrystalline Cellulose Tribological Measurements

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以哲学态度看待家中老鼠

英语学习 2009年第1期 31-33页

作者： Richard O'mara

一群灰褐色、一眨眼就跑得不见踪影的小生物彻底破坏了我宁静的生活，妻子惊慌颤抖、我倍感烦扰，灭鼠药、捕鼠器乃至灭鼠专家都无济于事。看着老鼠在家中四处乱窜，最终我想到可以用哲学的方法来对待它们……

关键词：哲学态度老鼠灭鼠药

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那灵魂,朴素如梅子的核,内里有宇宙

青年视觉 2018年第3期 186-203页

作者：李怡 mara Sanchez-Renero 不详

“过去并非仅是一个描述性的历史概念,它首先是对现在的定义。”摄影师mara说。而世上的人,有谁能幸免于遗忘?过去只是序幕,死亡闪耀如洪荒永恒中的星辰,历史成为经由过去传往未来的回声,墨西哥的命运成为这一切的缩影。今日墨西哥举国... 详细信息

“过去并非仅是一个描述性的历史概念,它首先是对现在的定义。”摄影师mara说。而世上的人,有谁能幸免于遗忘?过去只是序幕,死亡闪耀如洪荒永恒中的星辰,历史成为经由过去传往未来的回声,墨西哥的命运成为这一切的缩影。今日墨西哥举国狂欢的亡灵节(Diadelos Muertos)是阿兹特克(Aztec)文明活人献祭仪式、古代印第安土著人以祭念逝者和西班牙天主教诸圣节杂的产物,人们从10月31日开始,连续在接下来两日的幼灵节和成灵节和家人齐聚一堂,载歌载舞,为“死亡”这一生命的新开始庆祝。与之类似,和绵延三干余年的传统、信仰一同在近五百年内被重构的,还有种族和血统。

关键词：亡灵节阿兹特克土著人墨西哥印第安

Invasive Infections for Endemic Fungi in Pediatrics in Guatemala

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World Journal of AIDS 2018年第3期8卷 63-75页

作者： Julio Werner Juárez Lorenzana María Luisa navarro Gómez Andrea Palma Comprehensive Care Unit of HIV and Chronic Infections “Dr. Carlos Rodolfo Mejia” Roosevelt Hospital Guatemala City Guatemala Infectious Diseases Section Pediatrics Service School of Medicine Complutense University of Madrid University General Universitario Gregorio Mara&ntilde ón Madrid Spain General Physician Rafael Landívar University Guatemala City Guatemala

Background: Invasive fungal infections are common opportunistic diseases in patients with AIDS, other conditions related to immunodeficiency and healthy infants. Most publications on this subject are related to industrialized countries, and in adult population, with limited data in Latin America (except for Brazil, Colombia, and Argentina), and especially in pediatric population. These patients present a variety of clinical manifestations representing a diagnostic and therapeutic challenge for the health system. Objective: The objective of the study is to describe the epidemiological and laboratory characteristics of children with invasive fungal infections in Guatemala. Methods: A review of the microbiology service database was carried out at Roosevelt Hospital in Guatemala. Positive cultures were taken from children under 15 years of age, in a period of seven years, from 2007 to 2014, with its corresponding medical history. Results: Finally, 23 isolates were documented but only 15 patients were included in the study with complete information;10 Histoplasma capsulatum cases, 4 Cryptococcus neoformans cases and 1 Coccidioidessp case. The average age was 7 years old for Histoplasma and 9 years old for Criptococo, with an age range from 6 months to 14 years. Around 60% of the patients were older than 5 years, of which, more than two-thirds were HIV positive children without antiretroviral therapy, who presented an invasive fungal infection at the time of HIV diagnosis. These infections are endemic in Guatemala, so the distribution was mostly uniform. Around 80% of the patients had some disease related to immunodeficiency and 70% were infected with human immunodeficiency virus (HIV). The microbiological isolation was from blood, bone marrow, lymph nodes, cerebrospinal fluid and urine. The predominant laboratory findings were decrease in hematological series. The most frequent clinical syndromes were fever, adenomegaly, hepatosplenomegaly, respiratory, gastrointestinal,

关键词： Cryptococcosis Histoplasmosis Coccidioidomycosis Invasive Infection Pediatrics Immunodeficiency HIV (Human Immunodeficiency Virus)

Chemometric Analysis of an Sanitary Landfill Leachate

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Journal of Water Resource and Protection 2012年第1期4卷 16-24页

作者： Ana M.C. Grisa Cíntia Paese Oclide José Dotto Ronaldo Nicola mara Zeni 不详

This paper presents a study on the biotic/abiotic conditions of the S?o Giácomo sanitary landfill, located near the city of Caxias do Sul, Brazil, through statistical analysis of fourteen physic-chemical data sets for the leachate, produced in the garbage dump site over a long period of years. Different chemometric methods are used in the statistical analysis. For example, the correlations between the variables, related to the degraded organic matter and biological activity, are determined by means of multivariate methods. The results highlight that BOD, COD, VTS, FTS and TS give information on the anaerobic degradation of the organic matter contained in the cells, and suggest that the greater the contribution of the variables with positive weights in PC1 the greater the level of organic matter degradation. The variables TN, Amon Nit. and alkalinity are related to the biological activity and determine the potency of the variables in relation to time. The greater the contribution of the variables related to organic degradation the greater the values in PC2 and the lesser the potency of these variables, whose influence is greater in the second stage of anaerobic degradation. The variables of PC2 is important plans of the contamination of the leached in the bodies hídrics.

关键词： Landfill Leachate Physico-Chemical Variables Chemometric Method Principal Components Analysis

Hepatocellular carcinoma and microbiota:Implications for clinical management and treatment

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World Journal of Hepatology 2022年第7期14卷 1319-1332页

作者： Dario Spanu Andrea Pretta Eleonora Lai mara Persano Clelia Donisi Stefano Mariani Marco Dubois Marco Migliari Giorgio Saba Pina Ziranu Valeria Pusceddu Marco Puzzoni Giorgio Astara Mario Scartozzi Medical Oncology Unit University Hospital and University of CagliariMonserrato 09042CagliariItaly

Gut microbiota plays an essential role in host *** is involved in several physiological processes such as nutrients digestion and absorption,maintenance of intestinal epithelial barrier integrity and immune system *** the gut microbiota is assumed to play a crucial role in many gastrointestinal,pancreatic and liver *** role in hepatic carcinogenesis is also gaining increasing interest,especially regarding the development of therapeutic *** studies are highlighting a link between some bacterial strains and liver disease,including hepatocellular carcinoma(HCC).Indeed,HCC represents an interesting field of research in this perspective,due to the gut-liver axis,to the implication of microbiota in the immune system and to the increasing number of immunotherapy agents investigated in this ***,the assessment of the role of microbiota in influencing clinical outcome for patients treated with these drugs is becoming of increasing *** review aims to give an overview on the relationship between microbiota and HCC development/progression and *** focus on potential implications on the available treatment strategies and those under study in the various stages of *** highlight the pathogenic mechanisms and investigate the underlying molecular pathways ***,we investigate the potential prognostic and/or predictive role of microbiota for target therapies,immune checkpoint inhibitors and loco-regional ***,given the limitation of current treatments,we analyze the gut microbiota-mediated therapies and its potential options for HCC treatment focusing on fecal microbiota transplantation.

关键词： Hepatocellular carcinoma Gut microbiota Gut-liver axis Fecal microbiota transplantation Carcinogenesis Immune checkpoint inhibitors

Comparison between Elderly Persons of the Urban Community, According to the Indicative of Depression

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Open Journal of Nursing 2017年第2期7卷 158-168页

作者： Lilane Maria Alves Silva Sheron Hellen da Silva Darlene mara dos Santos Tavares Leiner Resende Rodrigues The Federal University of Triângulo Mineiro Uberaba MG Brazil

Objectives: To compare the sociodemographic and economic profile, functional capacity, number of self-referred morbidities and level of physical activity among the elderly with and without indicative of depression. Methods: Cross-sectional and analytical study, with 980 elderly persons (250 with and 730 without indicative of depression) residing in the city of Uberaba, in the State of Minas Gerais, Brazil, between August 2012 and May 2013. We used the BOMFAQ Questionnaire, GDS 15, Katz Index, Lawton and Brody Scale and IPAQ. For data analysis, descriptive statistics and the Chi-square test (p Results: In the comparison between the groups, there were significant differences regarding the female gender (p = 0.009), education (p = 0.008), individual income (p Conclusion: The comparison of the existence or not of depressive symptoms among the elderly enables a more effective planning of public policies aimed at health promotion and adequate treatment in cases of disease already present and the subsidization of preventive strategies, using data such as risk factors and associated factors and ways to research depression.

关键词： Depression Aged Motor Activity Activities of Daily Living

Synchronous and Asynchronous Blastomere Cleavage at Cryopreservation: Effect on Subsequent Embryo Survival, Pregnancy and Live Birth Rates

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Journal of Biomedical Science and Engineering 2014年第5期7卷 243-251页

作者： Zofnat Wiener-Megnazi Maria Fridman mara Koifman Shirly Lahav-Baratz Nili Stein Ron Auslender martha Dirnfeld Department of Community Medicine and Epidemiology Carmel Medical Centre Rappaport Faculty of Medicine Technion Haifa Israel Fertility and IVF Unit Department of Obstetrics and Gynecology Carmel Medical Centre Rappaport Faculty of Medicine Technion Haifa Israel

Capsule: Although embryos with synchronous blastomere cleavage showed higher post-thaw survival rates, pregnancy rates did not differ. Thus, embryos with all cleavage patterns may be safely cryopreserved. Objective: To compare post-thaw embryo survival, pregnancy and live birth rates of embryos with synchronous vs asynchronous blastomere cleavage in frozen embryo transfer (FET) cycles. Design: Retrospective study. Setting: University-affiliated IVF unit. Patients: One thousand and sixty FET cycles performed from 2004-2006. Interventions: Cycles were divided into 3 groups: 1: cycles in which only embryos with synchronous blastomere cleavage were frozen;2: cycles in which only embryos with asynchronous blastomere cleavage were frozen;3: cycles in which both embryos with synchronous and asynchronous blastomere cleavage were frozen. Clinical and laboratory data were recorded and analyzed. Main Outcome Measures: Post-thaw embryo survival, morphologic grading, pregnancy and live birth rates. Results: A total of 1863 embryos were analyzed. Synchronous embryos had higher blastomere survival rates and morphological grading at thawing. Pregnancy and birth rates did not differ among groups. In a multivariant logistic regression analysis, a number of transferred embryos and embryo morphological grading at thawing were the only parameters that affected pregnancy and live birth rates. Conclusions: Embryos with both synchronous and asynchronous blastomere cleavage can be selected by classical embryo grading and safely cryopreserved.

关键词： Embryo Survival Blastomere Cleavage Frozen-Thawed Embryos IVF Pregnancy Synchronicity

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山羊MPO和IDO1基因变异分析

山羊MPO和IDO1基因变异分析

作者：阿达马（Adama mara）华中农业大学

学位级别：硕士

本研究旨在研究山羊IDO1和MPO基因受到正选择的单核苷酸多态性位点(Single Nucleotide Polymorphism, SNP)。在研究中,我们通过测定脱氧核糖核酸序列的方法得到了106只山羊中IDO1基因的多态性,最终在IDO1序列的外显子2-3和外显子10区域... 详细信息

本研究旨在研究山羊IDO1和MPO基因受到正选择的单核苷酸多态性位点(Single Nucleotide Polymorphism, SNP)。在研究中,我们通过测定脱氧核糖核酸序列的方法得到了106只山羊中IDO1基因的多态性,最终在IDO1序列的外显子2-3和外显子10区域中共得到了5个突变位点。随后对IDO1基因外显子2-3(G290A;T309C)和外显子10(G290A;T309C)的进行基因分型,并通过聚合酶链式反应(Polymerase Chain Reaction, PCR)检测多态性位点。我们在MPO基因的外显子3-4中发现了一些突变,但是并未导致氨基酸变化。由于密码子的简并性,这些突变并未改变编码蛋白的氨基酸序列,最终成为对机体没有影响的沉默突变。系统发生分析表明,山羊IDO1和MPO基因与绵羊具有最高的相似性,高达98%和99%,与此同时山羊MPO基因与斑马鱼和小鼠仅有72%和83%的相似性。通过似然比检验,在使用朴素贝叶斯方法(Naive Empirical Bayes, NEB)分析正选择M8位点时候发现,IDO1和MPO表现出了较为丰富的参数信息。结果显示IDO1基因中有10个位点受到正选择(IDO1的LRTs分别为3.184和18.858,MPO为33.124)。这些位点包括350R、371N、398L、400T、302E、435T、231K、213I、210Y、18T (P>0.95);MPO有五个位点51E、652E(P>0.95)、325S、742S、765G(P>0.99)。由于只有大约15%的褪黑素是通过这条通路被分解的并且在这个通路中的相同位点上,这两个基因承担的任务相同。因此,我们推测IDO1和MPO基因在进化过程中受到正选择驱动。

关键词： Indoleamine1 Myeloperoxydase SNP Variation genetic Positive Selection