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From liver to hormones:The endocrine consequences of cirrhosis

World Journal of Gastroenterology 2024年第9期30卷 1073-1095页

作者： Juan Eduardo Quiroz-Aldave Elman Rolando Gamar.a-Osorio mar.a del Carmen Durand-Vásquez Luciana del Pilar Rafael-Robles Jhean Gabriel Gonzáles-Yovera mar.a Alejandra Quispe-Flores Luis Alberto Concepción-Urteaga Alejandro Román-González José Paz-Ibarra marcio José Concepción-Zavaleta Non-communicable Diseases Endocrinology Research LineHospital de Apoyo ChepénChepén 13871Peru Department of Endocrinology Hospital Víctor Lazarte EchegarayTrujillo 13006Peru Department of Endocrinology Clínica Javier PradoLima 15046Peru Department of Gastroenterology Hospital Nacional Guillermo Almenara IrigoyénLima 15018Peru Department of Endocrinology Hospital de Emergencias GrauLima 15001Peru Internal Medicine Hospital Regional Docente de TrujilloTrujillo 13011Peru Department of Endocrinology Hospital Universitario de San Vicente FundaciónMedellin 050010Colombia Internal Medicine Universidad de AntioquiaMedellín 050010Colombia School of Medicine Universidad Nacional Mayor de San MarcosLima 15081Peru Department of Endocrinology Hospital Nacional Edgardo Rebagliati MartinsLima 15072Peru Carrera de Medicina Humana Universidad Científica del SurLima 15067Peru

Hepatocrinology explores the intricate relationship between liver function and the endocrine *** liver diseases such as liver cirrhosis can cause endocrine disorders due to toxin accumulation and protein synthesis *** its importance,assessing endocrine issues in cirrhotic patients is frequently *** article provides a comprehensive review of the epidemiology,pathophysiology,diagnosis,and treatment of endocrine disturbances in liver *** review was conducted using the PubMed/Medline,EMBASE,and Scielo databases,encompassing 172 *** cirrhosis is associated with endocrine disturbances,including diabetes,hypoglycemia,sarcopenia,thyroid dysfunction,hypogonadotropic hypogonadism,bone disease,adrenal insufficiency,growth hormone dysfunction,and secondary *** optimal tools for diagnosing diabetes and detecting hypoglycemia are the oral glucose tolerance test and continuous glucose monitoring system,*** can be assessed through imaging and functional tests,while other endocrine disorders are evaluated using hormonal assays and imaging *** options include metformin,glucagon-like peptide-1 analogs,sodium-glucose co-transporter-2 inhibitors,and insulin,which are effective and safe for diabetes *** standards are followed for managing hypoglycemia,and hormone replacement therapy is often necessary for other endocrine *** transplantation can address some of these problems.

关键词： Diabetes mellitus Hypoglycemia Thyroid diseases Hypogonadism Metabolic bone diseases Liver cirrhosis

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The Effectiveness of the Havriliak-Negami Model in Predicting the Master Curves of the Asphalt Blends with SBS Triblock Copolymer and Organic-Montmorillonite at Different Temperatures and Frequencies

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Journal of Materials Science and Chemical Engineering 2024年第7期12卷 23-39页

作者： mar.a Ángeles Vargas-Hernández Miguel Ángel Vargas Pedro R. García-morán Humberto Vázquez-Torres Divisin de Ingeniera Qumica y Bioqumica TecNMTecnolgico de Estudios Superiores de Ecatepec Edo. de Mxico Mxico Facultad de Qumica Universidad Nacional Autonma de Mxico Cd. de Mxico Mxico Facultad de Ciencias Bsicas Ingeniera y Tecnologa Universidad Autnoma de Tlaxcala Tlaxcala Mxico Departamento de Fsica Universidad Autnoma Metropolitana-Iztapalapa Cd. de Mxico Mxico

The dynamic viscoelastic properties of asphalt AC-20 and its composites with Organic-Montmorillonite clay (OMMt) and SBS were modeled using the empirical Havriliak-Negami (HN) model, based on linear viscoelastic theory (LVE). The HN parameters, α, β, G0, G∞and τHN were determined by solving the HN equation across various temperatures and frequencies. The HN model successfully predicted the rheological behavior of the asphalt and its blends within the temperature range of 25˚C - 40˚C. However, deviations occurred between 40˚C - 75˚C, where the glass transition temperature Tg of the asphalt components and the SBS polymer are located, rendering the HN model ineffective for predicting the dynamic viscoelastic properties of composites containing OMMt under these conditions. Yet, the prediction error of the HN model dropped to 2.28% - 2.81% for asphalt and its mixtures at 100˚C, a temperature exceeding the Tg values of both polymer and asphalt, where the mixtures exhibited a liquid-like behavior. The exponent α and the relaxation time increased with temperature across all systems. Incorporating OMMt clay into the asphalt blends significantly enhanced the relaxation dynamics of the resulting composites.

关键词： Asphalt Blends Master Curve Linear Viscoelasticity Havriliak-Negami Model

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Multitasking Behavior and Perceptions of Academic Performance in University Business Students in Mexico during the COVID-19 Pandemic

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International Journal of Mental Health Promotion 2022年第4期24卷 565-581页

作者： Victoria Gonzáles-Gutierrez Aldo Alvarez-Risco Alfredo Estrada-Merino mar.a de las Mercedes Anderson-Seminario Sabina Mlodzianowska Shyla Del-Aguila-Arcentales Jaime A.Yáñez CETYS Universidad MexicaliBaja CaliforniaMexico Universidad de Lima Facultad de Ciencias Empresariales y EconómicasCarrera de Negocios InternacionalesLimaPeru Escuela Nacional de marina Mercante“Almirante Miguel Grau” CallaoPeru Universidad Norbert Wiener Vicerrectorado de InvestigaciónLimaPeru Teoma Global Gerencia Corporativa de Asuntos Científicos y RegulatoriosLimaPeru

The current study measures the inﬂuence of multitasking behavior and self-efﬁcacy for self-regulated learning(SESRL)on perceptions of academic performance and views in university students during the COVID-19 pan-demic in Mexico.264 university students fulﬁlled an online *** was observed that multitasking beha-vior negatively inﬂuences SESRL(-0.203),while SESRL showed a positive inﬂuence of 0.537 on perceptions of academic performance,and multitasking behavior had an inﬂuence of-0.097 on the perception of academic ***’s alpha and Average Variance Extracted values were 0.809 and 0.577(multitasking behavior),0.819 and 0.626(SESRL),0.873 and 0.725(perceptions of academic performance),*** results of the bootstrapping test showed that the path coefﬁcients were signiﬁ*** study outcomes can support new plans in universities to ensure the best academic *** study showed evidence of the COVID-19 impact on education *** study’s novelty is based on using the partial least square structural equation modeling(PLS-SEM)technique to evaluate these variables.

关键词： Multitasking behavior COVID-19 Mexico self-efﬁcacy for self-regulated learning academic performance online class pandemic Peru

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Impact of diff erent waves of COVID-19 on emergency medical services and out-of-hospital cardiopulmonary arrest in Madrid, Spain

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World Journal of Emergency Medicine 2022年第5期13卷 386-389页

作者： Jose-mar.a Navalpotro-Pascual Diana Monge martín Manuel-José González León Fernando Neria Serrano Carlos Alonso Blas Belén Muñoz Isabel Yago Muñecas Cuesta Alfredo Carrillo Moya Juan les González Alonso Mateos Rodríguez Madrid Emergency Medical Services SUMMA 112Madrid 28045Spain School of Medicine Francisco de Vitoria UniversityMadrid 28223Spain(School of MedicineUniversidad Francisco de VitoriaMadrid 28223Spain)

Out-of-hospital cardiac arrest(OHCA)is one of the three leading causes of death in industrialized countries.[1,2]Some studies have described the impact of the first COVID-19 pandemic wave in terms of the number of cases and OHCA survival rates in various regions,[3-5]but few have addressed the relationship between the successive phases and how they affected OHCA.[6,7]The 14-d cumulative incidence peaked at more than 990 cases,with these rates remaining above 200 for an eight-month period between 15 march 2020 and 15 march 2021 in Madrid,Spain.

关键词： cardiac services successive

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Powder metallurgy with space holder for porous titanium implants:A review

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Journal of Materials Science & Technology 2021年第17期76卷 129-149页

作者： Alejandra Rodriguez-Contreras Miquel Punset JoséA.Calero Francisco Javier Gil Elisa Ruperez Josémar.a Manero Biomaterials Biomechanics and Tissue Engineering Group(BBT)Department of Materials Science and EngineeringUniversitat Politecnica de Catalunya(UPC)Av.Edurad Maristany 1608019BarcelonaSpain Barcelona Research Centre in Multiscale Science and Engineering Technical University of Catalonia(UPC)Av.Eduard Maristany 10-1408019BarcelonaSpain UPC Innovation and Technology Center(CIT-UPC).Technical University of Catalonia(UPC) C.Jordi Girona 3-108034Barcelona.Spain AMES GROUP SA.Carretera Nacional 340 Pol.Ind."Les Fallulles"08620Sant Vicenc dels HortsBarcelonaSpain Bioengineering Institute for Technology Universitat Intemacional de Catalunyac/Josep Trueta s/n08195BarcelonaSpain

One of the biggest challenges in the biocompatibility of implantable metals is the prevention of the stress shielding effect,which is related to the coupling of the bone-metal mechanical *** stress shielding phenomenon provokes bone resorption and the consequent adverse effects on prosthesis ***,it can be inhibited by adapting the stiffness of the implant *** the use of titanium(Ti)porous structures is a great alternative not only to inhibit this effect but also to improve the osteointegration of orthopedic and dental implants,a brief description of the techniques used for their manufacturing and a review of the current commercialized implants produced from porous Ti assemblies are compiled in this *** powder metallurgy(PM)with space holder(SH)is a powerful technology used to produce porous Ti structures,it is here discussed its potential for the fabrication of medical devices from the perspectives of both design and *** most important parameters of the technique such as the size and shape of the initial metallic particles,the SH and binder type of materials,the compaction pressure of the green form,and in the sintering stage,the temperature,atmosphere,and time are reviewed according to the bibliography ***,the importance of the porosity and its types together with the influence of the mentioned parameters in the final porosity and,consequently,in the ultimate mechanical properties of the structure are ***,a few examples of the PM-SH application for the manufacturing of orthopedic implants are presented.

关键词： Powder metallurgy Space holder method Porous titanium structures Medical devices Stress shielding effect Porous materials permeability Interconnected porosity Porous bone substitute materials Open-cell titanium foams Sintering-dissolution technique

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Diversity and seasonal variation of ground and understory spiders from a tropical mountain cloud forest

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Insect Science 2020年第4期27卷 826-844页

作者： Emmanuel F.Campuzano Guillermo Ibarra-Nunez Salima Machkour-M Rabet Alejandro moron-Rios mar.a Luisa Jimenez Colegio de la Frontera Sur(ECOSUR) Unidad TapachulaTapachulaChiapasMexico ECOSUR Unidad ChetumalChetumalQuintana RooMexico ECOSUR Unidad CampecheCampecheCampecheMexico Centro de Investigaciones Biologicas del Noroeste(CIBNOR) La PazBaja California SurMexico

We made intensive samplings to study the seasonal response of spiders across different forest strata(ground and understory)in a tropical mountain cloud forest from *** sampled spiders from ten plots in six sampling events during the dry and rainy season,to analyze their abundance,structure(distribution of abundance among species),diversity and the response of the five dominant species at each *** demonstrated that seasonal patterns of spider communities differed among strata,revealing a complex spatiotemporal ***,structure,diversity of ground spiders,as well as the responses of four dominant species at this stratum,showed low seasonal *** contrast,a strong seasonal variation was observed for the understory assemblage,with lowest abundance and highest diversity in the rainy season,and different assemblage structures for each *** patterns of each assemblage seem linked to the responses of their dominant *** found high co-occurrence among most of the ground dominant species with similar habitat use and with multivoltine patterns,contrasting with low co-occurrence among most of the understory dominant species with similar habitat use and univoltine *** results showed that the spiders’assemblages of tropical mountain cloud forest(opposed to what is found in temperate and boreal forests)increase their species richness with the height,and that their responses to seasonal change differ between *** programs of these habitats should consider the spatial and temporal variations found here,as a better understanding of their ecological dynamics is required to support their sustainable management.

关键词： community structure El Triunfo Biosphere Reserve interspecific competition Mexico temporal change vertical stratification

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Male genitourinary schistosomiasis-related symptoms among long-term Western African migrants in Spain: a prospective population-based screening study

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贫困所致传染病(英文) 2024年第2期13卷 29-38页

作者： Roure Sílvia Vallès Xavier Pérez-Quílez Olga López-Mu?oz Israel Chamorro Anna Abad Elena Valerio Lluís Soldevila Laura Espa?a Sergio Hegazy Alaa H. A. Fernández-Rivas Gema Gorriz Ester Herena Dolores Oliveira Mário Miralles mar.a Carme Conde Carmen Montero-Alia Juan José Fernández-Pedregal Elia Miranda-Sánchez Jose Llibre Josep M. Isnard mar Bonet Josep mar.a Estrada Oriol Prat Núria Clotet Bonaventura The Schisto-Stop study group International Health Program (PROSICS) Barcelona North Metropolitan Territorial Directorate for Infectious Diseases Catalan Institute for Health CAP La Salut Passatge dels Encants S/N Badalona Spain Fundació Lluita contra les Infeccions c/Can Ruti s/n Badalona Spain Infectious Diseases Department Hospital Universitari Germans Trias i Pujol c/Can Ruti s/n Badalona Spain Germans Trias i Pujol Research Institute c/Can Ruti s/n Badalona Spain Microbiology Department Germans Trias i Pujol University Hospital c/Can Ruti s/n Badalona Spain Department of Genetics and Microbiology Universitat Autònoma de Barcelona c/Can Ruti s/n Badalona Spain Faculty of Medicine University of Asyut El Fateh Assiut Governorate Egypt Department of Urology Germans Trias i Pujol University Hospital c/Can Ruti s/n Badalona Spain Canovelles Primary Health Care Unit Barcelona North Metropolitan Health Directorate Catalan Institute for Health C/Indústria Canovelles Spain Primary Health Care Unit Mataró-(Rocafonda-Palau) Barcelona North Metropolitan Health Directorate Catalan Institute for Health Camí Ral el Ravalet Mataró Barcelona Spain Barcelona North Metropolitan Primary Care Directorate Catalan Institute for Health Ctra. de Barcelona Sabadell Barcelona Spain Directorate for Innovation and Interdisciplinary Cooperation Barcelona North Metropolitan Health Directorate Catalan Institute for Health C/Can Ruti S/N Badalona Spain IrsiCaixa-AIDS Research Institute Hospital Universitari Germans Trias i Pujol University Hospital c/Can Ruti s/n Badalona Spain Infectious Diseases Directorate Barcelona North Metropolitan Health Directorate Catalan Institute for Health C/Can Ruti S/N Badalona Spain

Background Schistosomiasis is highly endemic in sub-Saharan Africa and frequently imported to Europe. Male urogenital manifestations are often neglected. We aimed to ascertain the prevalence of genitourinary clinical signs and symptoms among long-term African migrants in a non-endemic European country using a serology *** We carried out a prospective, community-based cross-sectional study of adult male migrants from sub-Saharan Africa living in *** serology tests and microscopic urine examinations were carried out, and clinical data were obtained from an electronic medical record search and a structured *** We included 388 adult males, mean age 43.5 years [Standard Deviation (SD) = 12.0, range: 18–76]. The median time since migration to the European Union was 17 [Interquartile range (IQR): 11–21] years. The most frequent country of origin was Senegal (N = 179, 46.1%). Of the 338, 147 (37.6%) tested positive forSchistosoma. Parasite eggs were present in the urine of only 1.3%. Nine genitourinary clinical items were significantly associated with positiveSchistosoma serology results: pelvic pain (45.2%;OR = 1.57, 95%CI: 1.0–2.4), pain on ejaculation (14.5%;OR = 1.85, 95%CI: 1.0–3.5), dyspareunia (12.4%;OR = 2.45, 95%CI: 1.2–5.2), erectile dysfunction (9.5%;OR = 3.10, 95%CI: 1.3–7.6), self-reported episodes of infertility (32.1%;OR = 1.69, 95%CI: 1.0–2.8), haematuria (55.2%;OR = 2.37, 95%CI: 1.5–3.6), dysuria (52.1%;OR = 2.01, 95%CI: 1.3–3.1), undiagnosed syndromic STIs (5.4%), and orchitis (20.7%;OR = 1.81, 95%CI: 1.0–3.1). Clinical signs tended to *** Urogenital clinical signs and symptoms are prevalent among male African long-term migrants with a positiveSchistosoma serology results. Genital involvement can be frequent even among those with long periods of non-residence in their sub-Saharan African countries of origin. Further research is needed to develop diagnostic tools and validate therapeutic approaches to

关键词： Schistosomiasis Chronic schistosomiasis Urogenital schistosomiasis Male genital schistosomiasis Longterm migrant

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An Important Pool of Sucrose Linked to Starch Biosynthesis is Taken up by Endocytosis in Heterotrophic Cells

An Important Pool of Sucrose Linked to Starch Biosynthesis i...

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The Second International Symposium on Plant Neurobiology

作者： Edurne Baroja-Fernandez Ed Etxeberria Francisco José Muoz mar.a Teresa morán-Zorzano Nora Alonso-Casajús Pedro Gonzalez Javier Pozueta-Romero Agrobioteknologia Instituta Nafarroako Unibertsitate Publikoa Gobierno de Navarra and Consejo Superior de Investigations CientificasMutiloako etorbidea zenbaki gabe31192 MutiloabetiNafarroaSpain University of Florida IFAS Citrus Research and Education Center700 Experiment Station RoadLake Alfred FL33850USA Agrobioteknologia Instituta Nafarroako Unibertsitate Publikoa Gobierno de Navarra and Consejo Superior de Investigations CientificasMutiloako etorbidea zenbaki gabe31192 MutiloabetiNafarroaSpain Agrobioteknologia Instituta Nafarroako Unibertsitate Publikoa Gobierno de Navarra and Consejo Superior de Investigations CientificasMutiloako etorbidea zenbaki gabe31192 MutiloabetiNafarroaSpain Agrobioteknologia Instituta Nafarroako Unibertsitate Publikoa Gobierno de Navarra and Consejo Superior de Investigations CientificasMutiloako etorbidea zenbaki gabe31192 MutiloabetiNafarroaSpain University of Florida IFAS Citrus Research and Education Center700 Experiment Station Road Lake Alfred FL33850USA Agrobioteknologia Instituta Nafarroako Unibertsitate Publikoa Gobierno de Navarra and Consejo Superior de Investigaciones CientificasMutiloako etorbidea zenbaki gabe31192 MutiloabetiNafarroaSpain

＜正＞We have recently shown the occurrence of endocytic sucrose uptake in heterotrophic cells （Etxeberria et al. Plant Cell Physiol. 46, 474-481）. Whether this mechanism is involved in the sucrose-starch conversion process was investigated by comparing the rates of starch accumulation in sycamore cells cultured in the presence or absence of the endocytic inhibitors wortmannin and LY294002. These analyses revealed a two-phase process involving an initial 120 min wortmannin- and

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How does anodization time affect morphological and photocatalytic properties of iron oxide nanostructures?

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Journal of Materials Science & Technology 2020年第3期38卷 159-169页

作者： Bianca Lucas-Granados Rita Sánchez-Tovar Ramón MFernández-Domene Josémar.a Estívalis-martínez JoséGarcía-Antón Ingeniería Electroquímica y Corrosión(IEC).Instituto Universitario de Seguridad Industrial Radiofísica y Medioambiental(ISIRYM)Universitat Politècnica de ValènciaCamino de Vera s/n46022ValenciaSpain Departmento de Ingeniería Química Universitat de ValènciaAv de les Universitatss/n46100 BurjassotSpain

Iron oxide nanostructures are promising materials to be used as photocatalysts in different photoelectrochemical applications. There are different techniques in order to synthesize these nanostructures, but one of the most inexpensive and simple method is electrochemical anodization. This method can lead to different nanostructures by controlling its parameters. Anodization time is one of the most critical parameters since it considerably affects the properties of the obtained nanostructures. In this work, different anodization times(5, 10, 15, 30 and 60 min) were studied. The resulting nanotubes were characterized by field emission scanning electron microscopy, Raman laser confocal microscopy, water splitting measurements, Mott-Schottky analysis and electrochemical impedance spectroscopy, in order to test their viability for being used as photocatalysts in photoelectrochemical applications. Results showed that the best photocurrent density values in water splitting tests(0.263 m A m-2) were achieved for the sample anodized for 10 min under hydrodynamic conditions.

关键词： Iron oxide Metallic nanostructures Photoelectrochemistry Anodization Time

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Diagnosis and management of small bowel neuroendocrine tumors:A state-of-the-art

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World Journal of Methodology 2022年第5期12卷 381-391页

作者： Jhean Gabriel Gonzáles-Yovera Pela J Roseboom marcio Concepción-Zavaleta Isamar Gutiérrez-Córdova Esteban Plasencia-Dueñas mar.a Quispe-Flores Anthony Ramos-Yataco Carlos Alcalde-Loyola Frederick Massucco-Revoredo JoséPaz-Ibarra Luis Concepción-Urteaga Division of Gastroenterology María Auxiliadora HospitalLima 15801Peru Division of Emergency Medicine Regional Academic Hospital of TrujilloTrujillo 13011Peru Division of Endocrinology Stella Maris ClinicLima 15084Peru Division of Gastroenterology Guillermo Almenara Irigoyen National HospitalLima 12590Peru Division of Endocrinology Guillermo Almenara Irigoyen National HospitalLima 12590Peru Division of Internal Medicine Ricardo Cruzado Rivarola HospitalIca 110301Peru School of Medicine National University of TrujilloTrujillo 13007Peru Department of Medicine School of MedicineNational University of San MarcosLima 15001Peru Division of Internal Medicine School of MedicineNational University of TrujilloTrujillo 13011Peru

This review provides an update on the epidemiology,pathophysiology,symptoms,diagnosis and treatment of neuroendocrine neoplasms(NENs)of the small bowel(SB).These NENs are defined as a group of neoplasms deriving from neuroendocrine *** are currently the most common primary tumors of the SB,mainly involving the ileum,making the SB the most frequently affected part of the gastrointestinal *** NENs by definition are located between the ligament of Treitz and the ileocecal *** are characterized by small size and induce an extensive fibrotic reaction in the small intestine including the mesentery,resulting in narrowing or twisting of the *** manifestations of bowel functionality are related to the precise location of the primary *** majority of them are non-functional NENs and generally asymptomatic;in an advanced stage,NENs present symptoms of mass effect by non-specific abdominal pain or carcinoid syndrome which appears in patients with liver metastasis(around 10%).The main manifestations of the carcinoid syndrome are facial flushing(94%),diarrhea(78%),abdominal cramps(50%),heart valve disease(50%),telangiectasia(25%),wheezing(15%)and edema(19%).Diagnosis is made by imaging or biochemical tests,and the order of request will depend on the initial diagnostic hypothesis,while confirmation will always be *** patients with a localized SB NEN with or without near metastasis in the mesentery are recommended for curative *** and distant spread may be susceptible to several therapeutic strategies,such as chemotherapy,somatostatin analogs and palliative resection.

关键词： Neuroendocrine Tumor Small bowel Small intestine Gastrointestinal disease Treatment Survival

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