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Fungal Diversity 2012年第4期55卷 143-154页

作者： teresa Lebel Colleen Peele Anneke Veenstra National Herbarium of Victoria Royal Botanic Gardens MelbournePrivate Bag 2000South YarraVictoria 3141Australia Life&Environmental Sciences Deakin UniversityMelbourneVictoriaAustralia

Galls induced by the gall-forming midges Asphondylia floriformis and *** on Sarcocornia quinqueflora,and *** and *** on Tecticornia arbuscula,were collected from two sites near Melbourne,*** belonging to a broad range of families were found to be associated with external surfaces of galls and articles of Sarcocornia ***,only Botryosphaeria dothidea was isolated from the fungal mycelium lining gall-midge larval chambers of all four Asphondylia species,on both host plants.

关键词： Gall-forming midges Botryosphaeria dothidea

Nilotinib:from animal-based studies to clinical investigation in Alzheimer's disease patients

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Neural Regeneration Research 2023年第4期18卷 803-804页

作者： Annalisa Nobili marcello D’Amelio maria teresa Viscomi Department of Medicine and Surgery University Campus Bio-MedicoDepartment of Experimental NeuroscienceIRCCS Santa Lucia FoundationRomeItaly Department of Life Science and Public Health Section of Histology and Embryology UniversitàCattolica del Sacro CuoreFondazione Policlinico Universitario“A.Gemelli”IRCCSRomeItaly

Since their first description in the brains of patients suffering from Alzheimer ’s disease(AD), more than 100 years ago, extracellular amyloid-β(Aβ) plaques and intracellular neurofibrillary tangles have been the principal focus of AD research. However, this focus has led to the failure of several long and promising clinical trials, and the efficacy of new Aβ-targeting drugs to slow down the disease progression is still controversial despite being successful in reducing the Aβ load.

关键词： Alzheimer Aβ drugs

Cytomegalovirus Hepatitis in Immunocompetent and Immunocompromised Hosts

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Journal of Clinical and Translational Hepatology 2021年第1期9卷 106-115页

作者： teresa Da Cunha George Y.Wu Department of Medicine Division of Gastroenterology-HepatologyUniversity of Connecticut Health CenterFarmingtonCTUSA Department of Medicine University of Connecticut Health CenterFarmingtonCTUSA

Human cytomegalovirus (HCMV) infection is common and affects between 40–100% of the worldwide population. However, the majority of cases are asymptomatic and when severe disease occurs, it is usually restricted to immunocompromised patients. Liver involvement by HCMV differs significantly, accordingly to the immune status of the host. In immunocompromised patients, particularly liver transplant patients, it often causes clinically significant hepatitis. On the other hand, in immunocompetent patients, HCMV hepatitis requiring hospitalization is extremely rare. This review aims to appraise studies regarding the pathophysiology of HCMV hepatitis, including mechanisms of latency and reactivation and its contribution to disease development, clinical presentation, diagnostic modalities and treatment, with a focus on comparing different aspects between immunocompromised and immunocompetent hosts.

关键词： CMV hepatitis Cytomegalovirus hepatitis Cytomegalovirus hepatitis immunocompetent Cytomegalovirus hepatitis immunocompromised

Sex-specific participation in inter-group conflicts within a multilevel society:the first evidence at the individual level

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Integrative Zoology 2013年第4期8卷 441-454页

作者： Dapeng ZHAO Zhuoyue CHEN Baoguo LI teresa ROMERO Tianjin Key Laboratory of Animal and Plant Resistance College of Life SciencesTianjin Normal UniversityTianjinChina College of Life Sciences Northwest UniversityXi’anChina Institute of Zoology Shaanxi Academy of SciencesXi’anChina Department of Cognitive and Behavioral Science Graduate School of Arts and SciencesUniversity of TokyoTokyoJapan Japan Society for the Promotion of Science ChiyodaTokyoJapan

Inter-group conflicts are common among many group-living animals and involve potentially complex motivations and *** living in multilevel societies offer a good opportunity to study inter-group *** study is the first to explore the function of sex-specific participation during inter-group conflicts within a multilevel society at the individual *** Sichuan snub-nosed monkey(Rhinopithecus roxellana)is an endangered seasonal breeding species living in a multilevel *** Sep 2007 to May 2008 we recorded 290 inter-group conflicts of a free-ranging provisioned band of *** in the Qinling Mountains of China to investigate the function of individual aggression during inter-group *** findings show that adult males were the main participants in inter-group conflicts,while females took part in them only *** male participation rate during the mating season,when adult females were estrous,was significantly higher than that during the non-mating ***,males directed their aggression to other males,and directed more intense aggression towards bachelor males than towards other resident *** both sexes,the participation rate as initiators was higher in the winter than that in the spring;and there was a significant positive correlation between group size and the participation rate as *** results suggest that inter-group aggression in Sichuan snub-nosed monkeys is linked to both mate defense and resource defense.

关键词： inter-group conflict mate defense multilevel society resource defense Rhinopithecus roxellana

Reviewing the discoverability and accessibility to data and information products linked to Essential Climate Variables

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International Journal of Digital Earth 2020年第2期13卷 236-252页

作者： maria teresa Miranda Espinosa Gregory Giuliani Nicolas Ray Institute for Environmental Sciences enviroSPACE labUniversity of GenevaGenevaSwitzerland Institute for Environmental Sciences GRID-GenevaUniversity of GenevaGenevaSwitzerland GeoHealth Group Institute of Global HealthFaculty of MedicineUniversity of GenevaGenevaSwitzerland'

Essential Climate Variables(ECVs)are geophysical records generated from systematic Earth Observations associated with climate variations,changes,and *** products support the data and information needs of international frameworks and policies such as the work of the United Nations Framework Convention on Climate Change(UNFCCC)and the Intergovernmental Panel on Climate Change(IPCC).We map the main networks and initiatives publishing ECVs,by presenting an overview of existing satellite-based ECVs,their general data creation characteristics,discoverability and accessibility methods from an end-user *** investigate key initiatives providing or coordinating access to ECV data records,such as the Global Climate Observing System(GCOS),the Committee on Earth Observation Satellites(CEOS),the Coordination Group for Meteorological Satellites(CGMS),Joint Working Group on Climate(WGClimate),the Remote Sensing Systems(REMSS),and the European Space Agency Climate Change Initiative(ESA CCI).We find that ECV data discovery and access is difficult and time consuming due to the lack of common data and metadata *** addition,the selection of fit-for-purpose data records by end-users requires the implementation of interoperable standards and scalable data infrastructures to allow the generation of tailored applications and datadriven information products in support of decision-making processes.

关键词： Essential Climate Variables Climate services discoverability accessibility usability

The effect of salinity on Fucus ceranoides (Ochrophyta,Phaeophyceae) in the Mondego River(Portugal)

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Journal of Oceanology and Limnology 2019年第3期37卷 881-891页

作者： COTAS Joao FIGUEIRINHA Artur PEREIRA Leonel BATISTA teresa Department of Life Sciences University of CoimbraCoimbra 3001-456Portugal marE-marine and Environmental Sciences Centre Faculty of Science and TechnologyUniversity of CoimbraCoimbra 3000-548Portugal Laboratory of Pharmacognosy Faculty of PharmacyUniversity of CoimbraCoimbra 3000-548Portugal LAQV REQUIMTEFaculty of PharmacyUniversity of CoimbraCoimbra 3000-548Portugal CIEPQPF Department of Chemical EngineeringFaculty of Science and TechnologyUniversity of CoimbraCoimbra 3030-790Portugal

Algae(and their extracts)are increasingly important for pharmaceutical applications due to the diversity of useful compounds they *** genus Fucus contains one of the most studied species,Fucus *** species *** differs from the others of the genus by presenting longitudinal air-vesicles and a capacity to survive at low *** is an alga that inhabits the Mondego River estuary(Portugal),at the southern limit of its distribution,and can serve as a role model to understand the effect of a salt gradient on the production of bioactive *** assessed the phenolic content and antioxidant activity of different *** extracts(***,aqueous and polysaccharide)prepared from samples harvested from two different zones to evaluate if the adaptation of *** to different salinity levels influenced its chemical *** antioxidant activity of the extracts was determined using 1,2-diphenyl-picrylhydrazyl(DPPH)and 2.2-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid)(ABTS)*** assays demonstrated that the methanolic extract of lyophilized *** that grew at low salinities was the most bioactive,***(IC 50=50.39μg/mL)and ABTS(TEAC=2.42).The total phenolic content(Folin-Ciocalteu method)and the methanolic extract of the lyophilized *** collected from a low salinity habitat exhibited the highest phenolic content(PGE=49.48μg/mg of lyophilized extract)amongst those *** layer chromatography(TLC)and Fourier transform infrared spectroscopy(FTIR)were used for the identification of compounds in the *** characterization allowed confirmation that the various extracts contained almost the same compounds but with notable quantitative *** on these results,we conclude that there were differences in the quantity of the compounds due to the effect of *** drying methods used were also found to have influenced the quality of the extracted compounds.

关键词： Fucus ceranoides salinity gradient sequential extractions phenolic content dependent bioactivities spectroscopic analysis

A European digital accelerometric database:statistical analysis of engineering parameters of small to moderate magnitude events

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Earthquake Engineering and Engineering Vibration 2014年第4期13卷 583-597页

作者： Carlos S.Oliveira Gerard Gassol Xavier Goula teresa Susagna Instituto Superior Técnico Universidade de Lisboa Institut Cartogràfic i Geològic de Catalunya

During the NERIES Project, an accelerometric database containing European digital information was developed. Besides event and station metadata, ground motion parameters, computed in a homogeneous manner, were assembled： PGA, PGV, AI, TD, CAV, H1 and PSV（f,5%）（19,961 components, 2629 events, 547 stations）. Merging small and moderate magnitude events produced a unique database capable of providing important information such as：（i） Correlations between several ground motion parameters follow analogous trends as in previous worldwide datasets, with slight corrections. （ii） Although PGA attenuations with distance show great uncertainties, four recent GMPEs recommended for Europe fit quite well the central 50% data interval for the distance range 10 〈 R 〈 200 kin; outside these distances, they do not fit. （iii） Soil amplification ratios indicate that weak motion （low magnitudes and larger distances） shows larger amplification than strong motion （short distances and large magnitudes） as represented in UBC97 for the USA, but not in EC8 for Europe. （iv） Average spectral shapes are smaller than in the EC8. （v） Differences in amplification factors for PGA, PGV and HI for EC8 soil classes B and C, and differences in spectral shapes for these soil classes, indicate that EC8, Type 2 S-coefficient should be frequency dependent, as in UBC97.

关键词： NERIES project parametric accelerometric database European region PGA EC8 soil amplification

Reliability and validity of the Chinese version of the new fear of hypoglycemia scale: FH-15

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International Journal of Nursing Sciences 2018年第4期5卷 343-351页

作者： Ya-Qian Liu Si-Qi Xiong Ming Sang Yu-Feng Li maría teresa Anarte Ortiz Qiu-Ling Xing Hong-Mei Xu Chang-De Jin Department of Graduate Tianjin University of Traditional Chinese MedicineTianjinChina University of Malaga Spain The Ministry of Health Key Laboratory of Hormone and Development Metabolic Disease Hospital of Tianjin Medical UniversityChina Department of Nursing Tianjin University of Traditional Chinese MedicineTianjinChina

Objective:This study aimed to evaluate the reliability and validity of the Chinese version of the Fear of Hypoglycemia scale with 15 items(FH-15).Methods:After obtaining the original author's authorization,the English version of the FH-15 scale was translated,back translated,and culturally debugged to obtain the Chinese version of FH-15.A convenient sampling method was used to extract patients with type 2 diabetes from four tertiary hospitals in Tianjin.A total of 408 patients with type 2 diabetes were investigated in the hospital to test the reliability and validity of Chinese version FH-15 ***:The content validity index of the scale was 0.92,and the content validity index of each item was *** exploratory factor analysis extracted three common factors(fear,avoidance,and interference),which contained 15 items,and the cumulative variance contribution rate was 71.245%.The confirmatory factor analysis results showed that the model fit was better at 1.981 x2/df,GFI=0.901,CGI=0.962,TLI=0.952,and RMSEA=*** cut-off value for the total hypoglycemia fear scale was *** Cronbach'sαcoefficient of the three dimensions of the scale was 0.918,the Cronbach'sαcoefficient of each dimension is 0.876-0.916,the test-retest reliability was 0.903,and the test-retest reliability of each factor was ***:The Chinese version of the FH-15 scale can be considered reliable and *** item expression is concise,clear,and easy to *** is suitable for clinical practice as an initial screening tool to identify and evaluate the severity of fear of hypoglycemia in patients with type 2 diabetes.

关键词： Diabetes mellitus Type 2 Fear Hypoglycemia Reliability Validity

Naïve hepatitis B e antigen-negative chronic hepatitis B patients are at risk of carotid atherosclerosis:A prospective study

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World Journal of Gastroenterology 2021年第30期27卷 5112-5125页

作者： mar Riveiro-Barciela Cristina marcos-Fosch Fernando martinez-Valle Fabrizio Bronte Olimpia Orozco Isidro Sanz-Pérez Daniele Torres maria-teresa Salcedo Salvatore Petta Rafael Esteban Antonio Craxi maria Buti Department of Medicine of the UAB Hospital Universitari Vall d’HebronBarcelona 08035Spain Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas Instituto de Salud Carlos IIIMadrid 28029Spain Systemic Autoimmune Diseases Unit Internal Medicine DepartmentHospital Universitari Vall d'HebronBarcelona 08035Spain Sezione di Gastroenterologia Di.Bi.M.I.SUniversity of PalermoPalermo 90133Italy Pathology Department Hospital Universitari Vall d'HebronBarcelona 08035Spain

BACKGROUND There is an increased risk of atherosclerosis in patients with chronic hepatitis C or human immunodeficiency virus,but there is scarce data on hepatitis B virus *** hypothesis of this study is that hepatitis B virus infection increases the risk of carotid plaques and subclinical atherosclerosis in naïve hepatitis B e antigen(HBeAg)negative *** To assess the rate of carotid plaques and subclinical atherosclerosis in naïve HBeAg negative subjects in comparison with a cohort of healthy *** Prospective case-control collaborative study conducted in two tertiary *** hundred and two subjects prospectively recruited at the outpatient clinic were included from May 2016 to April 2017:201 naïve HBeAg-negative hepatitis B virus-infected[49 chronic hepatitis B(CHB)and 152 inactive carriers(ICs)]and 201 healthy *** and metabolic measures,liver stiffness and carotid Doppler ultrasound were *** atherosclerosis was established on an intima-media thickness increase of≥1.2 mm and/or the presence of carotid *** distributed quantitative variables were compared with the Student t test and those with a non-normal distribution with the Mann-Whitney U *** variables were compared between groups using theχ2 or Fisher exact *** Carotid plaques were found more often in CHB(32.7%)than ICs(17.1%)or controls(18.4%)(P=0.048).Subclinical atherosclerosis was also increased in CHB(40.8%)vsICs(19.1%)or controls(19.4%)(P=0.003).No differences in the risk of atherosclerosis were observed between controls and *** factors independently associated with the presence of carotid plaques were age[odds ratio(OR)1.43,P<0.001]and CHB(OR 1.18,P=0.004)and for subclinical atherosclerosis,age(OR 1.45,P<0.001),CHB(OR 1.23,P<0.001)and diabetes(OR 1.13,P=0.028).In the subset of young subjects(<50 years),carotid plaques(12.5%vs 1.1%,P=0.027)and subclinical atherosclerosis(12.5%vs 2.2%,P=0.058

关键词： Hepatitis B virus Carotid plaques Subclinical atherosclerosis Cardiovascular risk Endothelial dysfunction Intima-media thickness

Diesel and welding aerosols in an underground mine

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International Journal of Mining Science and Technology 2020年第4期30卷 449-454页

作者： Aleksandar D.Bugarski teresa L.Barone Jon A.Hummer National Institute for Occupational Safety and Health Pittsburgh Mining Research DivisionPittsburghPA 15236USA

Researchers from the National Institute for Occupational Safety and Health(NIOSH)conducted a study in an isolated zone of an underground mine to characterize aerosols generated by:(1)a diesel-powered personnel carrier vehicle operated over a simulated light-duty cycle and(2)the simulated repair of existing equipment using manual metal arc welding(MMAW).Both the diesel-powered vehicle and MMAW process contributed to concentrations of nano and ultrafine aerosols in the mine *** welding process also contributed to aerosols with electrical mobility and aerodynamic mobility count median diameters of approximately 140 and 480 nm,*** welding particles collected on the filters contained carbon,iron,manganese,calcium,and aluminum.

关键词： Diesel aerosols Welding aerosols Underground mining Size distribution