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Lipase inhibitory activity of Lagenaria siceraria fruit as a strategy to treat obesity

Asian Pacific Journal of Tropical Medicine 2017年第3期10卷 285-290页

作者： Maria maqsood Dildar Ahmed Iqra Atique Wajeeha Malik Department of Chemistry Forman Christian College(A Chartered University)LahorePakistan

Objective:To explore pancreatic lipase inhibitory activity under different extraction conditions in order to track the most potent ***:The methanolic extract and its fractions in solvents of increasing polarity,ether,chloroform,ethyl acetate,n-butanol and water,were made through cold *** in ethanol,ethyl acetate,acetone and chloroform were similarly *** extract was prepared through hot decoction method.A reported method was used to determine lipase inhibitory activity of extracts and fractions over wide ranges of ***:The extracts and fractions exhibited concentration dependent *** IC50(μg/mL)values of methanolic,ethanolic,chloroform,ethyl acetate,acetone,ethyl acetate(after washing with water)and aqueous decoction were 293.40,266.47,157.59,182.12,352.34,257.00,and 190.00,*** activity of chloroform,ethyl acetate and aqueous extracts were close to that of the drug orlistat(IC50 146μg/mL).Out of the fractions of the methanolic extract,the chloroform fraction was most active(IC50 189.6μg/mL).The order of inhibitory activity of the fractions was as follows:chloroform>ether>n-butanolic>aqueous>ethyl *** GC/MS analysis of the most active chloroform faction showed the presence of hexadecanoic acid,methyl hexadecanoate,isopropyl palmitate,methyl 9,12-octadecadienate,and methyl 9,12,***:The study suggests that Lagenaria siceraria has potential to inhibit pancreatic lipase activity,suppressing lipid digestion and thereby diminishing entry of lipids into the *** intake of aqueous decoction of the fruit may therefore be recommended for control of *** acids and their esters may play role as inhibitors of lipase.

关键词： Lagenaria siceraria Obesity Lipase inhibitory activity Bottle gourd

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Natural convection of CuO–water nanofluid filled in a partially heated corrugated cavity:KKL model approach

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Communications in Theoretical Physics 2020年第8期72卷 27-42页

作者： rizwan Ul Haq Muhammad Usman Ebrahem A Algehyne Department of Electrical Engineering Bahria UniversityIslamabadPakistan BIC-ESAT College of EngineeringPeking UniversityBeijing 100871China State Key Laboratory for Turbulence and Complex Systems Department of Mechanics and Engineering SciencePeking UniversityBeijing 100871China Department of Mathematics Faculty of SciencesUniversity of TabukP.O.Box 741Tabuk 71491Saudi Arabia

In this article, flow and heat transfer inside a corrugated cavity is analyzed for natural convection with a heated inner obstacle. Thermal performance is analyzed for Cu O–water inside a partially heated domain by defining the constraint along the boundaries. For nanofluid analysis, the Koo and Kleinstreuer Li(KKL) model is implemented to deal with the effective thermal conductivity and viscosity. A heated thin rod is placed inside the corrugated cavity and the bottom portion of the corrugated cavity is partially heated. The dimensionless form of nonlinear partial differential equations are obtained through the compatible transformation along with the boundary constraint. The finite element method is executed to acquire the numerical solution of the obtained dimensional system. Streamlines, isotherms and heat transfers are analyzed for the flow field and temperature distribution. The Nusselt number is calculated at the surface of the partially heated domain for various numerical values of emerging parameters by considering the inner obstacle at cold, adiabatic and heated conditions. The computational simulation was performed by introducing various numerical values of emerging parameters. Important and significant results have been attained for temperature and velocities(in both x-and y-directions) at the vertically and horizontally mean positions of the corrugated duct.

关键词： heat transfer nanofluid finite element method KKL corrugated cavity

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A challenging case of alpha-fetoprotein-result discrepancies in a patient with chronic hepatitis B

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Gastroenterology Report 2020年第6期8卷 484-486,I0003页

作者： Pir A.Shah Allison Onken rizwan Ishtiaq Muhammad H.maqsood Shyam S.Patel Karen J.Campoverde Reyes Adrianna Z.Herskovits Daryl T.Y.Lau Department of Medicine Liver CenterDivision of GastroenterologyBeth Israel Deaconess Medical CenterHarvard Medical SchoolBostonMAUSA Department of Pathology Beth Israel Deaconess Medical CenterHarvard Medical SchoolBostonMAUSA

Introduction Alpha-fetoprotein(AFP)is the most abundant serum protein found in the human fetus,produced by the yolk sac and the liver[1].The levels of maternal serum AFP reach a peak value at28-32 weeks of gestation and decrease rapidly after birth and usually drop to the normal at 8-12 months of *** normal serum AFP level for an adult is<20 ng/mL[2].In contrast,livertumor cells usually synthesize and secrete an increased level of *** ultrasound and AFP are generally recommended as the screening modality for HCC for patients at risk for development of hepatocellular carcinoma(HCC)[1].AFP-L3,an isoform of AFP that binds Lens culinaris agglutinin,can be particularly useful in the early identification of aggressive HCC[2].These assays,however,can generate false-positive and false-negative AFP *** patients with advanced HCC,20%had normal AFP levels,whereas some patients with liver diseases had significant AFP elevation without liver cancer in long-term surveillance[3].Elevated AFP levels could be associated with active liver diseases with hepatocyte regeneration[4,5].In that setting,the AFP level will decline with improvement of the underlying liver *** case illustrated the dilemma and uncertainties as a result of persistent abnormal AFP values after extensive clinical investigations.

关键词：甲胎蛋白 fetus false

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Advanced Techniques for Object-Based Classification of Hyperspectral Remote Sensing

Advanced Techniques for Object-Based Classification of Hyper...

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作者： SHAH,maqsood 南京理工大学

学位级别：硕士

Land-Use Land-Cover（LULC）mapping is an important issue in agriculture *** demand for improved and more accurate LULC mapping has led to a methodology known as object-based image analysis（OBIA）.The focus of this thesis is about the design and implementation of new methods for object-based（OB）classification of hyperspectral remote sensing *** earth observation instruments collect these ***,in this thesis we investigate the integration of methods for object-based hyperspectral classification in synergic *** images mapping is a crucial step in environmental monitoring,disaster management,agriculture management and military *** recent researches to improved and accurate hyperspectral mapping have led to key methodology known as Object-based classification of remotely sensed *** core intention of the OB images analysis is to group-of-pixels named "objects" through segmentation into a specific ***-oriented image analysis segments the data and constructs hierarchical network of homogeneous ***-based enable the analysis of aggregated sets of pixels,exploit shape-related variation,as well as spectral *** pixel-based classification methods always produce mixed pixel problems due to the independency of neighbor *** problem motivates researchers to combine segmentation,color and many other parameters to illuminate the wrongly classified or mixed pixels into their relevant *** the new methodology solved problems and improved accuracy,but it also raises new challenges such as the loss of accuracy in terms of less abundant,but potentially *** key challenges in hyperspectral images classification techniques are the high dimensionality of data,limited number of training samples,and combination of spatial and spectral *** recent years,availability of new remotely sensed data with high dimensions,spectral and spatial resolution rese

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Saliency-based framework for facial expression recognition

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Frontiers of Computer Science 2019年第1期13卷 183-198页

作者： rizwan Ahmed KHAN Alexandre MEYER Hubert KONIK Saida BOUAKAZ Universite de Lyon CNRSLIRISUMR5205Universite Lyon 1Lyon F-69622France Faculty of Information Technology Barrett Hodgson UniversityKarachi 74900Pakistan Laboratoire Hubert Curien UMR5516Universite Jean MonnetSaint-Etienne 42000France

This article proposes a novel framework for the recognition of six universal facial *** framework is based on three sets of features extracted from a face image:entropy,brightness,and local binary ***, saliency maps are obtained using the state-of-the-art saliency detection algorithm "frequency-tuned salient region detection".The idea is to use saliency maps to determine appropriate weights or values for the extracted features (i.e.,brightness and entropy).We have performed a visual experiment to validate the performance of the saliency detection algorithm against the human visual *** movements of 15 subjects were recorded using an eye-tracker in free-viewing conditions while they watched a collection of 54 videos selected from the Cohn-Kanade facial expression *** results of the visual experiment demonstrated that the obtained saliency maps are consistent with the data on human ***,the performance of the proposed framework is demonstrated via satisfactory classification results achieved with the Cohn-Kanade database,FG-NET FEED database, and Dartmouth database of children's faces.

关键词： facial expression recognition classification salient regions entropy brightness local binary pattern

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A unified approach of energy and data cooperation in energy harvesting WSNs

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Science China(Information Sciences) 2018年第8期61卷 170-182页

作者： Roomana YOUSAF rizwan AHMAD Waqas AHMED Fu-chun ZHENG School of Electrical Engineering and Computer Science National University of Sciences and Technology Department of Electrical Engineering Pakistan Institute of Engineering and Applied Sciences School of Electronic and Information Engineering Harbin Institute of Technology

Energy harvesting(EH) provisioned wireless sensor nodes are key enablers to increase network life time in modern wireless sensor networks(WSNs). However, the intermittent nature of the EH process necessitates management of nodes’ limited data and energy buffer capacity. In this paper, a unified mathematical model for a cooperative EHWSN with an opportunistic relay is presented. The energy and data causality constraints are expressed in terms of throughput, available energy, delay and transmission *** finite energy buffers, data buffers and discrete transmission rates(as defined in the standard IEEE 802.15.4) at the nodes, different intuitive online power allocation policies at the relay are *** results show that a policy achieving high throughput is less fair and vice versa. Therefore, a joint rate and power allocation policy(JRPAP) is proposed in this study which provides a better trade off between fairness, throughput and energy over intuitive policies. Based on the JRPAP results, we propose to use data aggregation(DA) to achieve throughput gain at lower buffer sizes. In addition, the notion of energy aggregation(EA) is introduced to achieve throughput gain at higher buffer sizes. Combining both EA and DA further improves the overall throughput at all buffer sizes.

关键词： energy harvesting energy causality data causality energy aggregation data aggregation opportunistic relay

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Investigating the Use of Email Application in Illiterate and Semi-Illiterate Population

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Computers, Materials & Continua 2020年第3期62卷 1473-1486页

作者： Sadeeq Jan Imran maqsood Salman Ahmed Zahid Wadud Iftikhar Ahmad National Center for Cyber Security-UETP Department of CS&ITUniversity of Engineering&TechnologyPeshawarPakistan Department of Computer Software Engineering University of Engineering&TechnologyMardanPakistan Department of Computer Systems Engineering University of Engineering&TechnologyPeshawarPakistan 不详

The use of electronic communication has been significantly increased over the last few *** is one of the most well-known means of electronic *** email applications are widely used by a large population;however,illiterate and semi-illiterate people face challenges in using them.A major population of Pakistan is illiterate that has little or no practice of computer *** this paper,we investigate the challenges of using email applications by illiterate and semi-illiterate *** addition,we also propose a solution by developing an application tailored to the needs of illiterate/semi-illiterate *** shows that illiterate people are good at learning the designs that convey information with pictures instead of text-only,and focus more on one object/action at a *** proposed solution is based on designing user interfaces that consist of icons and vocal/audio instructions instead of ***,we use background voice/audio which is more helpful than flooding a picture with a lot of *** tested our application using a large number of users with various skill levels(from no computer knowledge to experts).Our results of the usability tests indicate that the application can be used by illiterate people without any training or third-party’s help.

关键词： Illiterate semi-illiterate email usability user interfaces

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Water-Lubricated Ni-Based Composite(Ni-Al_2O_3,Ni-SiC and Ni-ZrO_2)Thin Film Coatings for Industrial Applications

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Acta Metallurgica Sinica(English Letters) 2016年第1期29卷 8-16页

作者： rizwan Sarwar Bajwa Zulfiqar Khan Vasilios Bakolas Wolfgang Braun Faculty of Science and Technology Sustainable Design Research CentreBournemouth University Talbot Campus Advanced Bearing Analysis Schaeffler Technologies GmbH& Co.KG

In this work, pure nickel and Ni-based nanocomposite coatings （Ni-AI2O3, Ni-SiC and Ni-ZrO2） were pro- duced on steel substrate by using pulse electrodeposition technique. The industrial performance tests were conducted to evaluate the wear resistance, corrosion resistance, adhesion strength and wettability behaviour of newly developed coat- ings. Rolling contact ball-on-disc tribometer was used to assess anti-wear behaviour of these coatings under water- lubricated contacts. The results showed that the wear- and corrosion resistance properties of nickel alumina and Ni-SiC composite coatings significantly improved than that of pure Ni and Ni-ZrO2 coatings. The adhesion and wettability results of Ni-A1203 composite showed better performance when compared to the rest of the coatings. The effects of incorporating nanoparticles on the surface microstructure, interface adhesion and distribution of the particles were also investigated. The coatings were characterized by using scanning electron microscopy, X-ray diffraction analysis and 3D white light inter- ferometry. The wear failure behaviour of these coatings was further examined by post-test surface observation under optical microscope.

关键词： Electrodeposition Wear-resistant Corrosion-resistant Tribology Nanocoatings Water-lubrication

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Boron nitride-based electrocatalysts for HER,OER,and ORR:A mini-review

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Frontiers of Materials Science 2021年第4期15卷 543-552页

作者： Nabi ULLAH rizwan ULLAH Saraf KHAN Yuanguo XU School of Materials Science and Engineering Jiangsu UniversityZhenjiang 212013China School of Chemistry and Chemical Engineering Jiangsu UniversityZhenjiang 212013China National Centre of Excellence in Physical Chemistry University of PeshawarPeshawar25120Pakistan Institute of Chemical Sciences University of PeshawarKhyber Pakhtunkhwa25120Pakistan

A reliable and efficient solution to the current energy crisis and its associated environmental issues is provided by fuel cells,metal-air batteries and overall water *** heart reactions for these technologies are oxygen reduction reaction(ORR),oxygen evolution reaction(OER)and hydrogen evolution reaction(HER).Different supporters such as graphene,carbon nanotube,and graphitic carbon nitride have been used to avoid agglomeration of active materials and provide maximum active surface for these *** all the supporters,boron nitride(BN)gains extensive research attention due to its analogue with graphene and excellent stability with good oxidation and chemical *** this mini-review,the well-known strategies(exfoliation,annealing,and CVD)used in the synthesis of BN with different morphologies for HER,OER and ORR applications have been briefly debated and *** comparative analysis determines that the performance and stability of state-of-the-art electrocatalysts can be further boosted if they are deposited on *** is revealed that BN-based catalysts for HER,OER and ORR are rarely studied yet especially with non-noble transition metals,and this research direction should be studied deeply in future for practical applications.

关键词： boron nitride electrocatalyst hydrogen evolution reaction oxygen evolution reaction oxygen reduction reaction

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Electric-field induced fluctuations in laser generated plasma plume

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Plasma Science and Technology 2021年第4期23卷 83-89页

作者： rizwan AHMED Abdul JABBAR Zeshan Adeel UMAR Muhammad Aslam BAIG National Centre for Physics Quaid-i-Azam University Campus45320 IslamabadPakistan

The effect of an external electric field on laser-generated plasma has been *** is observed that the laser-generated plasma can be used for the ignition of a spark in the presence of a low voltage external electric *** eight-fold emission intensity enhancement in Cu I spectral lines are measured as compared to the signal intensity in the absence of an external electric *** plasma parameters remain the same initially,up to a few microseconds after the generation of plasma,and this feature makes it more interesting for the quantitative analysis of any sample using laser induced breakdown spectroscopy(LIBS).In the presence of an external electric field,fluctuations(contraction and expansion)in the laser-generated plasma are observed which increase the plasma decay time and consequently result in enhanced signal intensity.

关键词： LIBS laser produced plasma effect of external electric plasma parameters

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