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Royal-jelly-based apitherapy can attenuate damages to male reproductive parameter following nicotine administration

Animal Models and Experimental Medicine 2022年第2期5卷 133-140页

作者： Mahsa nazar-Zadeh Cyrus Jalili Amene Nikgoftar Fathi Ali Ghanbari Mitra Bakhtiari Department of Anatomical Sciences Medical SchoolKermanshah University of Medical SciencesKermanshahIran Medical Biology Research Center Kermanshah University of Medical SciencesKermanshahIran Department of Anatomical Sciences Medical SchoolArak University of Medical SciencesArakIran

Background:Nicotine administration can generate severe oxidative stress and lipid *** jelly,with its antioxidant properties,acts as a scavenger of reactive oxygen *** study describes the apitherapy effects of royal jelly on testicular damage following nicotine ***:Forty-eight male BALB/c mice were divided into 8 groups(n=6):saline,3 different doses of royal jelly(100,150,and 200 mg/kg body weight(BW)per day),nicotine(1.5 mg/kg),and 3 different groups of Nic+Roy(1.5 mg/kg of Nic+100,150,and 200 mg/kg BW per day of royal jelly).Nicotine was administrated intraperitoneally,and royal jelly was prescribed orally for 10 consecutive *** levels of hormones(testosterone,luteinizing hormone,and follicle-stimulating hormone),total antioxidant capacity,nitric oxide(NO)status,malondialdehyde levels,sperm DNA fragmentation,sperm parameters,histopathological changes(H&E staining),immunohistochemistry against apoptotic proteins,and gene expression of Bcl-2,p53,Caspase-3,and Nrf2(real-time PCR)were assessed to evaluate the molecular and histological ***:Hormone levels,sperm parameters,and status of antioxidants were decreased significantly(p<.05)following nicotine ***,royal jelly treatment normalized hormonal and antioxidant characteristics,decreased apoptotic gene expression,increased Nfr2 gene expression,and restored histopathological alteration to the physiological status significantly(p<.05).Conclusion:Royal jelly upregulates the antioxidant status,inhibits the mitochondrialdependent apoptosis pathway,and increases the rate of *** therapeutic agent effectively protected the testis against nicotine-associated damages by antioxidant and anti-apoptotic effects.

关键词： antioxidant apitherapy apoptosis damage male nicotine reproduction royal jelly testis

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An Integrated Deep Learning Framework for Fruits Diseases Classification

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Computers, Materials & Continua 2022年第4期71卷 1387-1402页

作者： Abdul Majid Muhammad Attique Khan Majed Alhaisoni Muhammad Asfand Eyar Usman Tariq nazar Hussain Yunyoung Nam Seifedine Kadry Department of Computer Science HITEC University TaxilaTaxilaPakistan College of Computer Science and Engineering University of Ha’ilHa’ilSaudi Arabia Department of Computer Science Bahria UniversityIslamabad College of Computer Engineering and Sciences Prince Sattam Bin Abdulaziz UniversityAl-KhrajSaudi Arabia Department of Computer Science and Engineering Soonchunhyang UniversityAsanKorea Faculty of Applied Computing and Technology Noroff University CollegeKristiansandNorway

:Agriculture has been an important research area in the field of image processing for the last five *** affect the quality and quantity of fruits,thereby disrupting the economy of a *** computerized techniques have been introduced for detecting and recognizing fruit ***,some issues remain to be addressed,such as irrelevant features and the dimensionality of feature vectors,which increase the computational time of the ***,we propose an integrated deep learning framework for classifying fruit *** consider seven types of fruits,i.e.,apple,cherry,blueberry,grapes,peach,citrus,and *** proposed method comprises several important ***,data increase is applied,and then two different types of features are *** the first feature type,texture and color features,i.e.,classical features,are *** the second type,deep learning characteristics are extracted using a pretrained *** pretrained model is reused through transfer ***,both types of features are merged using the maximum mean value of the serial ***,the resulting fused vector is optimized using a harmonic threshold-based genetic ***,the selected features are classified using multiple *** evaluation is performed on the PlantVillage dataset,and an accuracy of 99%is achieved.A comparison with recent techniques indicate the superiority of the proposed method.

关键词： Fruit diseases data augmentation deep learning classical features features fusion features selection

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A Structural Model of the Endogenous Human BAF Complex Informs Disease Mechanisms

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四川生理科学杂志 2023年第4期45卷 2458-2458页

作者： nazar Mashtalir Department of Pediatric Oncology Dana-Farber Cancer Institute and Harvard Medical School Boston MA USA Broad Institute of MIT and Harvard Cambridge MA USA Laboratory of Molecular Electron Microscopy The Rockefeller University New York NY USA Department of Biochemistry University of Washington Seattle WA USA Institute for Systems Biology Seattle WA USA Chemical Biology Program Harvard Medical School Boston MA USA Laboratory of Biochemistry and Molecular Biology The Rockefeller University New York NY USA Department of Molecular Biosciences Northwestern University Evanston IL USA

Mammalian SWI/SNF complexes are ATP-dependent chromatin remodeling complexes that regulate genomic ***,we present a structural model of the endogenously purified human canonical BAF complex bound to the nucleosome,generated using cryoelectron microscopy(cryo-EM),cross-linking mass spectrometry,and homology *** complexes bilaterally engage the nucleosome H2A/H2B acidic patch regions through the SMARCB1 C-terminalα-helix and the SMARCA4/2 C-terminal SnAc/post-SnAc regions,with disease-associated mutations in either causing attenuated chromatin remodeling activities.

关键词： linking Human patch

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Summarizing Software Artifacts： A Literature Review

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Journal of Computer Science & Technology 2016年第5期31卷 883-909页

作者： Najam nazar Yan Hu He Jiang Key Laboratory for Ubiquitous Network and Service Software of Liaoning Province School of Software Dalian University of Technology Dalian 116621 China State Key Laboratory of Software Engineering Wuhan University Wuhan 430072 China

This paper presents a literature review in the field of summarizing software artifacts, focusing on bug reports, source code, mailing lists and developer discussions artifacts. From Jan. 2010 to Apr. 2016, numerous summarization techniques, approaches, and tools have been proposed to satisfy the ongoing demand of improving software performance and quality and facilitating developers in understanding the problems at hand. Since aforementioned artifacts contain both structured and unstructured data at the same time, researchers have applied different machine learning and data mining techniques to generate summaries. Therefore, this paper first intends to provide a general perspective on the state of the art, describing the type of artifacts, approaches for summarization, as well as the common portions of experimental procedures shared among these artifacts. Moreover, we discuss the applications of summarization, i.e., what tasks at hand have been achieved through summarization. Next, this paper presents tools that are generated for summarization tasks or employed during summarization tasks. In addition, we present different summarization evaluation methods employed in selected studies as well as other important factors that are used for the evaluation of generated summaries such as adequacy and quality. Moreover, we briefly present modern communication channels and complementarities with commonalities among different software artifacts. Finally, some thoughts about the challenges applicable to the existing studies in general as well as future research directions are also discussed. The survey of existing studies will allow future researchers to have a wide and useful background knowledge on the main and important aspects of this research field.

关键词： mining software repositories mining software engineering data machine learning summarizing softwar eartifacts summarizing source code

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Performance Analysis of Magnetic Nanoparticles during Targeted Drug Delivery:Application of OHAM

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Computer Modeling in Engineering & Sciences 2022年第2期130卷 723-749页

作者： Muhammad Zafar Muhammad Saif Ullah Tareq Manzoor Muddassir Ali Kashif nazar Shaukat Iqbal HabibUllah Manzoor Rizwan Haider Woo Young Kim Institute of Energy and Environmental Engineering University of the PunjabQuaid-e-Azam CampusLahore54590Pakistan Energy Research Centre COMSATS University IslamabadLahore54000Pakistan Department of Energy Engineering Faculty of Mechanical and Aeronautical EngineeringUniversity of Engineering and TechnologyTaxila47080Pakistan Department of Mathematics COMSATS University IslamabadLahore54000Pakistan School of Systems and Technology University of Management Sciences and TechnologyLahore54770Pakistan Department of Electrical Electronics and TelecommunicationEngineeringUniversity of Engineering and TechnologyLahore(FSD Campus)Faisalabad38000Pakistan Department of Electronic Engineering Faculty of Applied Energy SystemJeju National UniversityJeju Special Self-Governing ProvinceJeju-si63243Korea

In recent years,the emergence of nanotechnology experienced incredible development in the field of medical *** the past decade,investigating the characteristics of nanoparticles during fluid flow has been one of the intriguing *** distribution and uniformity have emerged as substantial criteria in both medical and engineering *** effects of chemotherapy on healthy tissues are known to be a significant concern during cancer therapy.A novel treatment method of magnetic drug targeting(MDT)has emerged as a promising topical cancer treatment along with some attractive advantages of improving efficacy,fewer side effects,and reduce drug *** magnetic drug targeting,the appropriate movement of nanoparticles(magnetic)as carriers is essential for the therapeutic process in the blood clot removal,infection treatment,and tumor cell *** this study,we have numerically investigated the behavior of an unsteady blood flowinfused with magnetic nanoparticles during MDT under the influence of a uniform external magnetic field in a *** optimal homotopy asymptotic method(OHAM)is employed to compute the governing equation for unsteady electromagnetohydrodynamics *** influence of Hartmann number(Ha),particle mass parameter(G),particle concentration parameter(R),and electro-osmotic parameter(k)is investigated on the velocity of magnetic nanoparticles and blood *** obtained show that the electro-osmotic parameter,along with Hartmann’s number,dramatically affects the velocity of magnetic nanoparticles,blood flow velocity,and flow ***,results also reveal that at a higher Hartman number,homogeneity in nanoparticles distribution improved *** particle concentration andmass parameters effectively influence the capturing effect on nanoparticles in the blood flow using a micro-tube for magnetic drug ***,investigation also indicates that the OHAM analysis is efficient and quick to h

关键词： Hartmann number magnetic nanoparticles nonlinear analysis targeted drug delivery optimal homotopy asymptotic method(OHAM)

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Boundary layer flow and heat transfer of a micropolar fluid near the stagnation point on a stretching vertical surface with prescribed skin friction

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International Journal of Minerals,Metallurgy and Materials 2011年第4期18卷 502-507页

作者： Kartini Ahmad Roslinda nazar Ioan Pop Centre for Foundation Studies International Islamic University Malaysia46350 Petaling JayaSelangorMalaysia School of Mathematical Sciences Faculty of Science and TechnologyUniversiti Kebangsaan Malaysia43600 UKM BangiSelangorMalaysia Faculty of Mathematics University of ClujR-3400 ClujCP 253Romania

The steady laminar mixed convection boundary layer flow and heat transfer of a micropolar fluid near the stagnation point on a stretched vertical surface with prescribed skin friction were *** governing partial differential equations were transformed into a system of ordinary differential equations,which were then solved numerically using the shooting *** for the stretching velocity,the local Nusselt number,the temperature,and the velocity profiles are presented for various values of the mixed convection parameter λ and material parameter K when the Prandtl number is equal to *** assisting（heated plate） and opposing（cooled plate） flow regions are *** is found that dual solutions exist for both assisting and opposing flows.

关键词： boundary layer flow dual solutions micropolar fluids mixed convection skin friction

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2000—2019年昌吉州植被覆盖度变化及土地荒漠化分析

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南方农业 2024年第7期18卷 68-72页

作者：刘润香那扎尔·夏汗哈孜阿力木江·吐斯依提新疆农业大学公共管理学院新疆乌鲁木齐830052

新疆维吾尔自治区昌吉回族自治州位于中国西部边陲,植被覆盖度面积相对较低,是荒漠化危害较为严重的地区之一。基于RS (Remote Sensing)和GIS (Geographic Information System)技术,对昌吉回族自治州植被覆盖度时空演变过程进行研究。... 详细信息

新疆维吾尔自治区昌吉回族自治州位于中国西部边陲,植被覆盖度面积相对较低,是荒漠化危害较为严重的地区之一。基于RS (Remote Sensing)和GIS (Geographic Information System)技术,对昌吉回族自治州植被覆盖度时空演变过程进行研究。结果表明:1)在2000—2019年,昌吉回族自治州土地荒漠化趋势较为严峻,19年间植被覆盖度面积波动减少、植被覆盖度下降,土地荒漠化面积加大、土地荒漠化加剧。2)不科学、不合理的人类社会经济活动对昌吉回族自治州植被覆盖变化的影响较大,迫切需要采用更为科学、合理的防治手段来减少人类社会经济活动对土地荒漠化的负面影响。

关键词：植被覆盖时空变化荒漠化新疆维吾尔自治区昌吉回族自治州

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MHD Flow Towards a Permeable Surface with Prescribed Wall Heat Flux

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Chinese Physics Letters 2009年第1期26卷 169-171页

作者： Anuar Ishak Roslinda nazar Ioan Pop School of Mathematical Sciences Universiti Kebangsaan Malaysia 43600 UKM Bangi Selangor Malaysia Faculty of Mathematics University of Cluj R-3400 Cluj CP 253 Romania

The steady magnetohydrodynamic （MHD） mixed convection flow towards a vertical permeable surface with prescribed heat flux is investigated. The governing partial differential equations are transformed into a system of ordinary differential equations, which is then solved numerically by a finite-difference method. The features of the flow and heat transfer characteristics for different values of the governing parameters are analysed and discussed. Both assisting and opposing flows are considered. It is found that dual solutions exist for the assisting flow, besides the solutions usually reported in the literature for the opposing flow.

关键词： field emission molybdenum dioxide enhancement factor

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Boundary Layer Flow over a Continuously Moving Thin Needle in a Parallel Free Stream

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Chinese Physics Letters 2007年第10期24卷 2895-2897页

作者： Anuar Ishak Rosllinda nazar Ioan Pop School of Mathematical Sciences Universiti Kebangsaan Malaysia 43600 UKM Bangi Selangor Malaysia Faculty of Mathematics University of Cluj R-3400 Cluj CP 253 Romania

We investigate the boundary-layer flow on a moving isothermal thin needle parallel to a moving stream. The governing equations are solved numerically by a finite-difference method. Dual solutions are found to exist wh... 详细信息

关键词： coated conductor buffer layer self-epitaxy CeO2

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Boundary Layer on a Moving Wall with Suction and Injection

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Chinese Physics Letters 2007年第8期24卷 2274-2276页

We investigate the boundary-layer flow on a moving permeable plate parallel to a moving stream. The governing equations are solved numerically by a finite-difference method. Dual solutions are found to exist when the ... 详细信息

关键词： coated conductor buffer layer self-epitaxy CeO2

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