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Journal of Rare Earths 2022年第10期40卷 1554-1563页

作者： Ajaz Ahmad Wani Amjad Mumtaz Khan Yahiya Kadaf Manea mansour a.s.salem Department of Chemistry Aligarh Muslim UniversityAMUAligarh202002India

Neodymium-doped Zn-Al layered double hydroxide(Nd/Zn-Al LDH) with excellent photocatalytic activity was prepared by a one-step hydrothermal method. The morphology and physicochemical properties of as-synthesized photocatalysts were well analyzed by Fourier transform infrared(FT-IR), X-ray diffraction(XRD), scanning electron microscopy(sEM), transmission electron microscopy(TEM), photoluminescence(PL), UV-diffuse reflectance spectroscopy(UV-DRs), and Brunauer-Emmett-Teller(BET)surface analysis. Doping Nd^(3+) into Zn-Al LDH enhances the overall catalytic activity of the nanocomposite, like better electron-hole pair separation, increase in interplanar distance, fast electron transfer, and large surface area. The as-prepared nanocomposite shows excellent degradation of three different dyes under visible light irradiation. The degradation efficiency of these dyes follows the order of Congo red > rose Bengal > fast green. Furthermore, liquid chromatography-mass spectrometry(LC-Ms)was employed to propose a possible photocatalytic degradation pathway for Congo Red and Rose Bengal dyes by Nd/Zn-Al LDH. With the help of radical trapping experiments, it is revealed that during the photoexcitation process, the primary reactive intermediates are hydroxyl radicals.

关键词： Organic pollutants Degradation Multifunctional Mesoporous LC-Ms Rare earths

MARIE:One-stage Object Detection Mechanism for Real-Time Identifying of Firearms

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Computer Modeling in Engineering & sciences 2025年第1期142卷 279-298页

作者： Diana Abi-Nader Hassan Harb Ali Jaber Ali mansour Christophe Osswald Nour Mostafa Chamseddine Zaki Computer science Department Faculty of SciencesLebanese UniversityBeirut146404Lebanon College of Engineering and Technology American University of the Middle EastEgaila54200Kuwait Lab-sTICC CNRS UMR 6285ENSTA-BretagneBrest29200France

security and safety remain paramount concerns for both governments and individuals *** today’s context,the frequency of crimes and terrorist attacks is alarmingly increasing,becoming increasingly intolerable to ***,there is a pressing need for swift identification of potential threats to preemptively alert law enforcement and security forces,thereby preventing potential attacks or violent *** advancements in big data analytics and deep learning have significantly enhanced the capabilities of computer vision in object detection,particularly in identifying *** paper introduces a novel automatic firearm detection surveillance system,utilizing a one-stage detection approach named MARIE(Mechanism for Realtime Identification of Firearms).MARIE incorporates the single shot Multibox Detector(ssD)model,which has been specifically optimized to balance the speed-accuracy trade-off critical in firearm detection *** ssD model was further refined by integrating MobileNetV2 and InceptionV2 architectures for superior feature extraction *** experimental results demonstrate that this modified ssD configuration provides highly satisfactory performance,surpassing existing methods trained on the same dataset in terms of the critical speedaccuracy *** these innovations,MARIE sets a new standard in surveillance technology,offering a robust solution to enhance public safety effectively.

关键词： Firearm and gun detection single shot multi-box detector deep learning one-stage detector MobileNet inception convolutional neural network

Nano-Enhanced Dairy scum Biodiesel Blends:Unleashing the Power of Aluminium Oxide for sustainable and Efficient Engine Performance

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Journal of Thermal science 2025年第1期34卷 283-302页

作者： Veeranna MODI Prasad B.RAMPURE sunil Kumar sHETTY Madeva NAGARAL Channa Keshava NAIK N Johar MGM Muhammad Irsyad ABDULLAH Abdullah I.AL-mansour shamshad ALAM KLE College of Engineering and Technology ChikodiVisvesvaraya Technological University Nitte (Deemed to be University) NMAM Institute of Technology (NMAMIT)Department of Mechanical Engineering Aircraft Research and Design Centre HAL Department of Mechanical Engineering BGS College of Engineering and TechnologyBengaluruAffiliated to Visvesvaraya Technological University Management and science University Department of Civil Engineering College of EngineeringKing Saud University

This study investigates the effect of aluminium oxide nanoparticlesaddition to biodiesel blends made from dairy milk scum on performance and combustion characteristics of the diesel *** dispersion of Al2O3nanoparticles in B20 blends at different concentrations was done with the help of *** number of blends were prepared for the *** Machine learning algorithms(Random Forest（RF）and CatBoost) was used for the *** results show that in comparison to biodiesel blends without nanoparticles,the kinematic viscosity and density is higher for fuel blends with *** these Fuel blends have higher calorific *** blends exhibited reduced Brake specific Fuel Consumption（BsFC） of2.85% than the blends without nano particles(Dairy scum Methyl Ester Biodiesel 20%+Neat Diesel 80%（in volume）,DsMEB20),57.14% less CO,40.8% less hydrocarbon,and increased NOxemissions compared to conventional diesel,contributing to the development of environmentally friendly and renewable biofuel blends with *** B20NP30 is the optimal blend for performance and emission *** study concludes with findings on enhanced Brake Thermal Efficiency（BTE） of 26.29% in 3×10-5（in volume） Al2O3nanoparticle-blended DsME B20 and other DsME B20 fuel blends,emphasizing the importance of optimal nanoparticle *** correlation matrix shows how engine load,efficiency measures（BTE,BsFC）,and emissions（CO,CO2,NOx,smoke） are connected in complex *** results help us understand the complicated dynamics of engine performance and emission characteristics ***'s diagram for BTE and BsFC shows that CatBoost-based BTE models perform superior to RF-based models during the training as well as testing *** results were obtained for CO and CO2emission results.

关键词： Al2O3 concentration CI engine Dairy scum Methyl Ester Biodiesel

Revisiting cerebral endothelial cells in Alzheimer’s disease

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Neural Regeneration Research 2025年第10期20卷 2911-2912页

作者： Amira s.Hanafy Department of Neurosurgery University Hospital BonnBonnGermany

Alzheimer’s disease(AD)is the most common neurodegenerative disorder characterized by slow and progressive decline of cognitive and memory *** only approximately 5%of the cases,AD is familial,as often predisposed by genetic mutations(Hoogmartens et al.,2021),while sporadic AD accounts for approximately 95%of the *** amyloid cascade hypothesis is one of the fundamental hypotheses put out to explain AD pathogenesis as dysregulated homeostasis of amyloid-β(Aβ)peptides that leads to the accumulation of Aβplaques in the parenchyma,an anatomical hallmark of AD.

关键词： Alzheimer Aβ cerebral

Emerging structures and dynamic mechanisms ofγ-secretase for Alzheimer’s disease

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Neural Regeneration Research 2025年第1期20卷 174-180页

作者： Yinglong Miao Michael s.Wolfe Computational Medicine Program and Department of Pharmacology University of North Carolina–Chapel HillChapel HillNCUSA Department of Medicinal Chemistry University of KansasLawrenceKSUSA

γ-secretase,called“the proteasome of the membrane,”is a membrane-embedded protease complex that cleaves 150+peptide substrates with central roles in biology and medicine,including amyloid precursor protein and the Notch family of cell-surface *** inγ-secretase and amyloid precursor protein lead to early-onset familial Alzheimer’s disease.γ-secretase has thus served as a critical drug target for treating familial Alzheimer’s disease and the more common late-onset Alzheimer’s disease as ***,critical gaps remain in understanding the mechanisms of processive proteolysis of substrates,the effects of familial Alzheimer’s disease mutations,and allosteric modulation of substrate cleavage byγ-*** this review,we focus on recent studies of structural dynamic mechanisms ofγ-*** mechanisms,including the“Fit-stay-Trim,”“sliding-Unwinding,”and“Tilting-Unwinding,”have been proposed for substrate proteolysis of amyloid precursor protein byγ-secretase based on all-atom molecular dynamics *** an incorrect registry of the Notch1 substrate was identified in the cryo-electron microscopy structure of Notch1-boundγ-secretase,molecular dynamics simulations on a resolved model of Notch1-boundγ-secretase that was reconstructed using the amyloid precursor protein-boundγ-secretase as a template successfully capturedγ-secretase activation for proper cleavages of both wildtype and mutant Notch,being consistent with biochemical experimental *** approach could be potentially applied to decipher the processing mechanisms of various substrates byγ-*** addition,controversy over the effects of familial Alzheimer’s disease mutations,particularly the issue of whether they stabilize or destabilizeγ-secretase-substrate complexes,is ***,an outlook is provided for future studies ofγ-secretase,including pathways of substrate binding and product release,effects of modulators on familial Alzheimer’s disease mutations

关键词： Alzheimer’s disease amyloid precursor protein cryo-EM structures drug design intramembrane proteolysis molecular dynamics Notch

Complementary roles of glial cells in generating region-specific neuroinflammatory responses and phagocytosis in Parkinson’s disease

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Neural Regeneration Research 2025年第10期20卷 2917-2918页

作者： Leyre Ayerra Maria s.Aymerich Universidad de Navarra Facultad de CienciasDepartamento de Bioquímica y GenéticaPamplonaSpain CIMA-Universidad de Navarra PamplonaSpain IdisNA Instituto de Investigación Sanitaria de NavarraPamplonaSpain

Neuroinflammation is associated with Parkinson’s disease:Reactive gliosis and neuroinflammation are hallmarks of Parkinson’s disease(PD),a multisystem neurodegenerative disorder characterized by a progressive loss of dopaminergic *** has long been considered a mere consequence of neuronal loss,but whether it promotes PD or is a key player in disease progression remains to be *** leukocyte antigen.

关键词： inflammation leukocyte generating

Vogt-Koyanagi-Harada syndrome and Crohn’s disease:an exceptional association

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Gastroenterology Report 2018年第1期6卷 65-67,I0003页

作者： Ahlem souguir Aya Hammami Wafa Dahmeni Hanene Jaziri Imed Ben mansour Ahlem Zayene Aida Ben slama Mehdi Ksiaa Ahlem Brahem salem Ajmi Ali Jmaa Department of Gastroenterology University Hospital SahloulSousseTunisia

Vogt-Koyanagi-Harada disease(VKH)is a rare,multisystem disease of melanocyte-containing *** is characterized by diffuse,granulomatous inflammation involving various *** has been reported to occur in association with other autoimmune *** report the case of a female patient who was diagnosed with VKH at the age of 4 years and who was treated with corticosteroids until the age of *** years later,Crohn’s disease was diagnosed,with a severe *** cases of VKH associated with ulcerative colitis have previously been reported anecdotally but,to our knowledge,this is the first case occurring in association to Crohn’s disease.

关键词： Vogt-Koyanagi-Harada disease granulomatous inflammation Crohn’s disease

Territorial behaviors and integration between buildings and city in urban public spaces of Iran's metropolises

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Frontiers of Architectural Research 2018年第4期7卷 588-599页

作者： mansour Yeganeh Mansoreh Kamalizadeh Department of Architecture Tarbiat Modares UniversityTehranIran

This paper studies the relationship between citizens׳ territorial behaviors and the levels and criteria of "integration of buildings and city in urban public spaces"(IBCUPs). The hypothesis of this research is that the levels of perception and integration criteria, of city and its buildings, will diverse based on citizens territorial behaviors. This theoretical proposition is analyzed in 7 urban streets at 3 Metropolises of Iran, by descriptive-analytical research method, followed by survey to serve the empirical aspect of research, which conducts within the framework of fuzzy logic. The results show a co-variation between the levels of territorial behavior and perception of integration. However, the criteria of integration between buildings and city were different in various urban public spaces according to the levels and types of citizens׳ territorial behaviors.

关键词： Tehran Tabriz Mashhad Territoriality Public space Quality Integrity of public spaces

Repurposed anti-cancer epidermal growth factor receptor inhibitors: mechanisms of neuroprotective effects in Alzheimer’s disease

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Neural Regeneration Research 2022年第9期17卷 1913-1918页

作者： Heba M.mansour Hala M.Fawzy Aiman s.El-Khatib Mahmoud M.Khattab Department of Pharmacology Egyptian Drug AuthorityEDAformerly NODCARGizaEgypt Department of Pharmacology and Toxicology Faculty of PharmacyCairo UniversityCairoEgypt

Numerous molecular mechanisms are being examined in an attempt to discover disease-modifying drugs to slow down the underlying neurodegeneration in Alzheimer’s *** studies have shown the beneficial effects of epidermal growth factor receptor inhibitors on the enhancement of behavioral and pathological sequelae in Alzheimer’s *** the promising effects of epidermal growth factor receptor inhibitors in Alzheimer’s disease,there is no irrefutable neuroprotective evidence in well-established animal models using epidermal growth factor receptor inhibitors due to many un-explored downstream signaling *** caused controversy about the potential involvement of epidermal growth factor receptor inhibitors in any prospective clinical *** this review,the mystery beyond the under-investigation of epidermal growth factor receptor in Alzheimer’s disease will be ***,their molecular mechanisms in neurodegeneration will be ***,we will shed light on sARs-COVID-19 induced neurological manifestations mediated by epidermal growth factor ***,we will discuss future perspectives and under-examined epidermal growth factor receptor downstream signaling pathways that warrant more *** conclude that epidermal growth factor receptor inhibitors are novel effective therapeutic approaches that require further research in attempts to be repositioned in the delay of Alzheimer’s disease progression.

关键词： Alzheimer’s disease autophagy drug re-positioning epidermal growth factor receptor human epidermal growth factor receptor-2 neurodegenerative diseases neuroinflammation oxidative stress tyrosine kinase inhibitors

Numerical Examination of the Effects of Ion Thermal Flow on Plasma sheath Characteristics

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Chinese Physics Letters 2013年第8期30卷 110-113页

作者： mansour Khoramabadi s.Farhad Masoudi Department of Physics Boroujerd BranchIslamic Azad UniversityP.O.Box 518BoroujerdIran Department of Physics K.N.Toosi University of TechnologyP.O.Box 15875-4416TehranIran

The effects of ion thermal flow on the electric and hydrodynamic characteristics of a plasma sheath are examined using a multi-fluid *** comparison with cold plasma,ion pressure is modeled by a power law dependence on the ion density in warm *** pressure force on the ion depends on the ion density,ion temperature,and a nearly constant parameter called the ion polytropic *** well-known quantities for this coefficient,γi=1 and 3,are considered,corresponding to isothermal and adiabatic flows,*** numerical calculations show that increasing the ion temperature decreases the sheath thickness and increases the ion impact energy and ion saturation current at the *** ion polytropic coefficient has the same effect as the ion temperature and intensifies the ion temperature effects.

关键词： coefficient coefficient quantities