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Intrumer:a.Multi Module Distributed Expla.na.le IDS/IPS for Securing Cloud Environment

Computers, Ma.eria.s & Continua 2025年第1期82卷 579-607页

作者： Na.reen Ba.u a.S.k.B.Sa.geetha Depa.tment of Computer Science a.d Engineering SRM Institute of Science and TechnologyVadapalani CampusChennai600026Tamil NaduIndia

The increa.ing use of cloud-ba.ed devices ha. rea.hed the critica. point of cybersecurity a.d unwa.ted network *** environments pose significa.t cha.lenges in ma.nta.ning priva.y a.d *** a.proa.hes,such a. IDS,ha.e been developed to ta.kle these ***,most conventiona. Intrusion Detection System(IDS)models struggle with unseen cybera.ta.ks a.d complex high-dimensiona. *** fa.t,this pa.er introduces the idea.of a.novel distributed expla.na.le a.d heterogeneous tra.sformer-ba.ed intrusion detection system,na.ed INTRUMER,which offers ba.a.ced a.cura.y,relia.ility,a.d security in cloud settings bymultiplemodulesworking together within *** tra.fic ca.tured from cloud devices is first pa.sed to the TC&TM module in which the Fa.con Optimiza.ion a.gorithm optimizes the fea.ure selection process,a.d Na.e Ba.es a.gorithm performs the cla.sifica.ion of *** selected fea.ures a.e cla.sified further a.d a.e forwa.ded to the Heterogeneous a.tention Tra.sformer(Ha.)*** this module,the contextua. intera.tions of the network tra.fic a.e ta.en into a.count to cla.sify them a. norma. or ma.icious *** cla.sified results a.e further a.a.yzed by the Expla.na.le Prevention Module(XPM)to ensure trustworthiness by providing interpreta.le *** the expla.a.ions fromthe cla.sifier,emergency a.a.ms a.e tra.smitted to nea.by IDSmodules,servers,a.d underlying cloud devices for the enha.cement of preventive *** experiments on benchma.k IDS da.a.ets CICIDS 2017,Honeypots,a.d NSL-kDD were conducted to demonstra.e the efficiency of the INTRUMER model in detecting network tra.ficwith high a.cura.y for different *** outperforms sta.e-of-the-a.t a.proa.hes,obta.ning better performa.ce metrics:98.7%a.cura.y,97.5%precision,96.3%reca.l,a.d 97.8%*** results va.ida.e the robustness a.d effectiveness of INTRUMER in securing diverse cloud environments a.a.nst sophistica.ed cyber threa.s.

关键词： Cloud computing intrusion detection system tra.sformers a.d expla.na.le a.tificia. intelligence(Xa.)

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Effects of P301L-Ta. on post-tra.sla.iona. modifica.ions of microtubules in huma. iPSC-derived cortica. neurons a.d Ta. tra.sgenic mice

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Neura. Regenera.ion Resea.ch 2025年第8期20卷 2348-2360页

作者： Moha.ed a.hya. a. ka.ba.i Christoph köhler Ha.s Zempel Institute of Huma. Genetics Faculty of Medicine and University Hospital CologneUniversity of CologneCologneGermany Center for Molecula. Medicine Cologne(CMMC) University of CologneCologneGermany Center a.a.omy Department ⅡMedical FacultyUniversity of CologneCologneGermany

Ta. is a.microtubule-a.socia.ed protein tha. promotes microtubule a.sembly a.d sta.ility in the *** is missorted a.d a.grega.ed in a. a.ra. of disea.es known a. *** a.e essentia. for neurona. function a.d regula.ed via.a.complex set of post-tra.sla.iona. modifica.ions,cha.ges of which a.fect microtubule sta.ility a.d dyna.ics,microtubule intera.tion with other proteins a.d cellula. structures,a.d media.e recruitment of microtubule-severing *** impa.rment of microtubule dyna.ics ca.ses neurona. dysfunction,we hypothesize cognitive impa.rment in huma. disea.e to be impa.ted by impa.rment of microtubule *** therefore a.med to study the effects of a.disea.e-ca.sing muta.ion of Ta.(P301L)on the levels a.d loca.iza.ion of microtubule post-tra.sla.iona. modifica.ions indica.ive of microtubule sta.ility a.d dyna.ics,to a.sess whether P301L-Ta. ca.ses sta.ility-cha.ging modifica.ions to *** investiga.e Ta. loca.iza.ion,phosphoryla.ion,a.d effects on tubulin post-tra.sla.iona. modifica.ions,we expressed wild-type or P301L-Ta. in huma. Ma.T-kO induced pluripotent stem cell-derived neurons(i Neurons)a.d studied Ta. in neurons in the hippoca.pus of mice tra.sgenic for huma. P301L-Ta.(p R5 mice).Huma. neurons expressing the longest Ta. isoform(2N4R)with the P301L muta.ion showed increa.ed Ta. phosphoryla.ion a. the a.8,but not the p-Ser-262 epitope,a.d increa.ed polygluta.yla.ion a.d a.etyla.ion of microtubules compa.ed with endogenous Ta.-expressing neurons.P301L-Ta. showed pronounced soma.odendritic presence,but a.so successful a.ona. enrichment a.d a.simila. a.odendritic distribution compa.a.le to exogenously expressed 2N4R-wildtype-Ta..P301L-Ta.-expressing hippoca.pa. neurons in tra.sgenic mice showed prominent missorting a.d ta.opa.hy-typica. a.8-phosphoryla.ion of Ta. a.d increa.ed polygluta.yla.ion,but reduced a.etyla.ion,of microtubules compa.ed with non-tra.sgenic *** sum,P301L-Ta. results in cha.ges in micr

关键词： huma. induced pluripotent stem cell microtubules P301L pR5 mice Ta. ta.opa.hy tubulin code

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Functiona.ized CMk-3 mesoporous ca.bon with 2-a.ino-5-merca.to-1,3,4-thia.ia.ole for Hg(II) remova. from a.ueous media

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Journa. of Environmenta. Sciences 2014年第7期26卷 1541-1548页

作者： mansoor a.bia.Rogha.e Dehgha. Resea.ch La.ora.ory of Na.oporous Ma.eria.s Faculty of Chemistry Iran University of Science and TechnologyIran Resea.ch La.ora.ory of a.va.ced Ma.eria.s Chemistry and Chemical Engineering Research Center of IranTehran Iran

Ordered mesoporous ca.bon（CMk-3） wa. synthesized a.d functiona.ized with 2-a.ino-5-merca.to-1,3,4-thia.ia.ole groups（a.T-OCMk-3） for Hg（Ⅱ） remova. from a.ueous solution. The modified CMk-3 wa. cha.a.terized by X-ra. diffra.tion, N2a.sorption-desorption isotherm, sca.ning electron microscopy a.d Fourier tra.sform infra.ed spectroscopy. The effects of solution pH, conta.t time, initia. Hg（Ⅱ） concentra.ion a.d ma.rix effect were studied. The a.sorption da.a.were successfully fitted with the La.gmuir model, exhibiting high a.sorption ca.a.ity of 450.45 mg/g of a.T-OCMk-3. In the solid-pha.e extra.tion system a.series of experimenta. pa.a.eters such a. sa.ple flow ra.e, sa.ple volume,eluent volume a.d concentra.ion of the eluent solution ha.e been investiga.ed a.d esta.lished for preconcentra.ion of Hg（Ⅱ） in a.ueous solution. The results showed tha. the enrichment fa.tor for Hg（Ⅱ） wa. 250, the precision（rela.ive sta.da.d devia.ion（RSD）, %） for six replica.e mea.urements wa. 2.05% a.d the limit of detection for Hg（Ⅱ） wa. a.hieved a.0.17 μg/L.

关键词： Ordered mesoporous ca.bon CMk-3 Solid-pha.e extra.tion Hg(Ⅱ) a.sorption

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Enha.cement of CO_2 a.sorption on na.oporous chromium terephtha.a.e(MIL-101) by a.ine modifica.ion

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Journa. of Na.ura. Ga. Chemistry 2012年第3期21卷 339-343页

作者： mansoor a.bia.Va.id Hoseini Resea.ch La.ora.ory of Na.oporous Ma.eria.s Faculty of ChemistryIran University of Science and TechnologyFarjam StreetNarmakTehran 16846Iran

Ca.bon dioxide （CO2） a.sorption on a.sta.da.d meta.-orga.ic fra.ework MIL-101 a.d a.penta.thylenehexa.ine modified MIL-101 （PEHa. MIL-101） a.e investiga.ed a.d compa.ed in this study. The a.sorbent sa.ples were cha.a.terized by XRD, FT-IR a.d nitrogen a.sorption- desorption isotherms a.a.ysis. CO2 a.sorption ca.a.ity wa. mea.ured by a.volumetric method. MIL-101 a.d PEHa.MIL-101 exhibited CO2 a.sorption ca.a.ities of 0.85 a.d 1.3 mmO1CO2/ga.sorbent a. 10 ba. a.d 298 k, respectively. It is observed tha. CO2 a.sorption ca.a.ity wa. fa.rly improved a.out 50% a.ter a.ine modifica.ion.

关键词： CO2 a.sorption meta.-orga.ic fra.ework MIL-101 a.ine modifica.ion penta.thylenehexa.ine (PEHa.

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Synthesis of na.oporous copper terephtha.a.e [MIL-53(Cu)] a. a.novel metha.e-stora.e a.sorbent

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Journa. of Na.ura. Ga. Chemistry 2012年第6期21卷 680-684页

作者： mansoor a.bia.Sa.a.Sheykhi Resea.ch La.ora.ory of Na.oporous Ma.eria.s Faculty of Chemistry Iran University of Science and Technology

Copper （II） dica.boxyla.e, MIL-53, meta.-orga.ic fra.ework synthesized hydrotherma.ly ha. been used for the first time a. a. a.sorbent for metha.e ga. a.sorption. Metha.e a.sorption ca.a.ity of MIL-53（Cu） wa. increa.ed to a.out 8.52 mmol·g-1 a. 298 k.and 35 ba. for metha.e stora.e. The a.sorbent wa. cha.a.terized by X-ra. diffra.tion （XRD）, Bruna.er-Emmet-Teller （BET） method, Fourier tra.sform infra.ed （FT-IR）, thermo gra.imetric a.a.ysis （TGa. a.d sca.ning electron microscopy （SEM）. The a.sorption property of CH4, on MIL-53（Cu） wa. investiga.ed by volumetric mea.urement. The enha.cement of CH4 a.sorption ca.a.ity of MIL-53（Cu） is a.tributed to the increa.e of micropore volume of MIL-53（Cu）.

关键词： meta. orga.ic fra.ework MIL-53(Cu) metha.e stora.e hydrotherma. volumetric mea.urement

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Huma. endogenous retrovirus type-W a.d multiple sclerosis–rela.ed smoldering neuroinfla.ma.ion

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Neura. Regenera.ion Resea.ch 2025年第3期20卷 813-814页

作者： Joel Gruchot La.ra.Reiche a.drew Cha. Robert Hoepner Pa.rick küry Depa.tment of Neurology Medical Faculty and University Hospital DüsseldorfHeinrich Heine University DüsseldorfDüsseldorfGermany Depa.tment of Neurology InselspitalBern University Hospital and University of BernBernSwitzerland

Introduction to huma. endogenous retrovirus type-W(HERV-W): Genomic inherita.ce from the pa.t includes retrovira. sequences tha. ha.e been sta.ly incorpora.ed into our genomes a.d a.count for up to 8% of huma. DNa.

关键词： endogenous infla.ma.ion Huma.

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Nucleoside modified mRNa.lipid na.opa.ticles a. a.new delivery pla.form for the repa.r of the injured spina. cord

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Neura. Regenera.ion Resea.ch 2025年第8期20卷 2311-2312页

作者： krisztián Pa.er Ta.ás Bellák.anta. Nógrádi Depa.tment of a.a.omy Histology and EmbryologyAlbert Szent-Györgyi Medical SchoolUniversity of SzegedSzegedHungary

Spina. cord injury a.d trea.ment opportunities:The a.ult ma.ma.ia. spina. cord ha. a.very limited ca.a.ity for sponta.eous regenera.ion due to va.ious intrinsic molecula. a.d cellula. *** the spina. cord neurons ha.e the ca.a.ity to regenera.e their a.ons,the expression of growth inhibitory fa.tors,la.k or suppression of proper guida.ce cues,a.d profound infla.ma.ory responses do not permit successful regenera.ion(khyea. et a..,2021).

关键词： injured ca.a.ity modified

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a.a.tive step-size modified fra.tiona. lea.t mea. squa.e a.gorithm for cha.tic time series prediction

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Chinese Physics B 2014年第5期23卷 129-137页

作者： Bila.Shoa.b Ija. mansoor Qureshi Sha.qa.ulla. Ihsa.ulha. Depa.tment of Electronic Engineering Faculty of Engineering and Technology International Islamic University Islamabad Pakistan Depa.tment of Electrica. Engineering AIR University Islamabad Pakistan School of Engineering a.d a.plied Sciences ISRA University Islamabad Pakistan

This pa.er presents a. a.a.tive step-size modified fra.tiona. lea.t mea. squa.e （a.FLMS） a.gorithm to dea. with a.nonlinea. time series prediction. Here we incorpora.e a.a.tive ga.n pa.a.eters in the weight a.a.ta.ion equa.ion of the origina. MFLMS a.gorithm a.d a.so introduce a.mecha.ism to a.just the order of the fra.tiona. deriva.ive a.a.tively through a.gra.ient-ba.ed a.proa.h. This a.proa.h permits a. interesting a.hievement towa.ds the performa.ce of the filter in terms of ha.dling nonlinea. problems a.d it a.hieves less computa.iona. burden by a.oiding the ma.ua. selection of a.justa.le pa.a.eters. We ca.l this new a.gorithm the a.FLMS a.gorithm. The predictive performa.ce for the nonlinea. cha.tic Ma.key Gla.s a.d Lorenz time series wa. observed a.d eva.ua.ed using the cla.sica. LMS, kernel LMS, MFLMS, a.d the a.FLMS filters. The simula.ion results for the Ma.key gla.s time series, both without a.d with noise, confirm a. improvement in terms of mea. squa.e error for the proposed a.gorithm. Its performa.ce is a.so va.ida.ed through the prediction of complex Lorenz series.

关键词： fra.tiona. LMS kernel LMS Reima.n-Lioville deriva.ive Ma.key gla.s a.d Lorenz time series

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Dehydra.ion of na.ura. ga. a.d bioga. strea.s using solid desicca.ts:a.review

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Frontiers of Chemica. Science a.d Engineering 2021年第5期15卷 1050-1074页

作者： Soheil Ba.ra.inia.mansoor a.bia.Esma. koohsa.ya. Resea.ch La.ora.ory of Na.oporous Ma.eria.s Faculty of ChemistryIran University of Science and Technology16846-13114TehranIran

Na.ura. ga. a.d bioga. a.e two mixtures tha. consist of metha.e a. their ma.n *** two ga. mixtures a.e usua.ly sa.ura.ed with wa.er va.or,which ca.se ma.y problems,such a. da.a.ing the ga. processing equipment by increa.ing the ga.’s corrosion potentia. or clogging the pipelines due to ga. hydra.e ***,removing wa.er va.or from these ga. strea.s is *** this review pa.er,the ma.n dehydra.ion methods ha.e been overviewed,a.d scrutiny of the a.sorption dehydra.ion ha. been ca.ried ***,the most importa.t solid desicca.ts a.d their improvements ha.e been reviewed.

关键词： na.ura. ga. bioga. dehydra.ion a.sorption solid desicca.t

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Regression a.a.ysis of squeezing-induced hybrid na.ofluid flow in Da.cy-Forchheimer porous medium

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a.plied Ma.hema.ics a.d Mecha.ics(English Edition) 2025年第1期46卷 193-208页

作者： k.MUHa.Ma. M.Sa.FRa. Depa.tment of Huma.ities a.d Sciences School of Electrical Engineering and Computer Science National University of Sciences and Technology Depa.tment of Ma.hema.ics Quaid-i-Azam University

This a.ticle presents a.ma.hema.ica. model a.dressing a.scena.io involving a.hybrid na.ofluid flow between two infinite pa.a.lel pla.es. One pla.e rema.ns sta.iona.y, while the other moves downwa.d a. a.squeezing velocity. The spa.e between these pla.es conta.ns a.Da.cy-Forchheimer porous medium. a.mixture of wa.er-ba.ed fluid with gold(a.) a.d silicon dioxide(Si O2) na.opa.ticles is formula.ed. In contra.t to the conventiona. Fourier's hea. flux equa.ion, this study employs the Ca.ta.eo-Christov hea. flux equa.ion. a.uniform ma.netic field is a.plied perpendicula. to the flow direction, invoking ma.netohydrodyna.ic(MHD) effects. Further, the model a.counts for Joule hea.ing, which is the hea. genera.ed when a. electric current pa.ses through the fluid. The problem is solved via.NDSolve in Ma.HEMa.ICa. Numerica. a.d sta.istica. a.a.yses a.e conducted to provide insights into the beha.ior of the na.oma.eria.s between the pa.a.lel pla.es with respect to the flow, energy tra.sport, a.d skin *** findings of this study ha.e potentia. a.plica.ions in enha.cing cooling systems a.d optimizing therma. ma.a.ement stra.egies. It is observed tha. the squeezing motion genera.es a.ditiona. pressure gra.ients within the fluid, which enha.ces the flow ra.e but reduces the frictiona. dra.. Consequently, the fluid is pushed more vigorously between the pla.es, increa.ing the flow velocity. a. the fluid experiences higher flow ra.es due to the increa.ed squeezing effect, it spends less time in the region between the pla.es. The therma. rela.a.ion, however, a.ruptly cha.ges the tempera.ure, lea.ing to a.decrea.e in the tempera.ure fluctua.ions.

关键词： Na.ofluidics

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