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Buckling of a ferromagnetic thin plate in a transverse static magnetic field

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Chinese Science Bulletin 1998年第19期43卷 1666-1670页

作者： Wentao Yang Hao Pan dali Zheng Qigong Cai Cent Iron & Steel Res Inst Beijing 100081 Peoples R China

An energy theory is proposed on the buckling of a ferromagnetic thin plate in a transverse static magnetic field. The analytic solution of critical field for plates is obtained by using variational method. It is shown that the critical magnetic field is not only influenced by the ratio of the thickness to the length, but also by the width, total length and the magnetic susceptibility of the specimen. Theoretical calculations agree with experiments reasonably.

关键词： static magnetic field ferromagnetic thin plate buckling energy theory.

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GECAM卫星溴化镧晶体性能研究

核电子学与探测技术 2024年第3期44卷 420-427页

作者：安正华张大力孙希磊李新乔熊少林杨生中国科学院高能物理研究所北京100049 核探测与核电子学国家重点实验室北京100049

GECAM卫星伽马射线探测器(GRD)设计使用3 in(1 in=25.4 mm)直径的溴化镧晶体(LaBr3晶体)作为伽马射线探测灵敏材料,后端耦合硅光电倍增管(SiPM)进行读出。对引力波最高能电磁对应体全天监测器(GECAM)卫星所用的LaBr_(3)晶体进行了本底测... 详细信息

GECAM卫星伽马射线探测器(GRD)设计使用3 in(1 in=25.4 mm)直径的溴化镧晶体(LaBr3晶体)作为伽马射线探测灵敏材料,后端耦合硅光电倍增管(SiPM)进行读出。对引力波最高能电磁对应体全天监测器(GECAM)卫星所用的LaBr_(3)晶体进行了本底测试,并根据晶体的掺杂类型进行了分类,使用放射源对所有晶体的性能进行了测试。为了研究LaBr_(3)晶体的辐照损伤情况,使用^(60)Co放射源对晶体进行了辐照损伤性能测试。测试结果表明,LaBr_(3)晶体的本底可分为单掺杂和双掺杂两个类型。GECAM卫星的LaBr_(3)晶体的能量分辨<18%@59.5 keV,满足设计使用要求。在1.65 kGy剂量的累积辐照后,经过较长时间的退激发,LaBr_(3)晶体试验前后662 keV的峰值变化小于15%,满足空间环境条件下(GECAM卫星在轨3年)的使用要求。

关键词： GECAM卫星溴化镧晶体伽马射线探测辐照损伤

A facile synthesis of goodyeroside A from (S)-malic acid

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Science China Chemistry 2009年第12期52卷 2176-2179页

作者： Feng Zhang Jun Wei dali Yin HaiHong Huang YanHong Zhang Institute of Materia Medica Chinese Academy of Medical Sciences and Peking Union Medical College Beijing 100050 China National Engineering Research Center for the Development of New Drugs Beijing 102600 China

Goodyeroside A 1,a natural product with hepatoprotective activity,was efficiently synthesized in a total yield of 47% in five steps starting from (S)-malic acid. The spectral data of the target compound 1 is identical... 详细信息

关键词： goodyeroside A esterification protecting group glycoside lactonization

Revealing the Solution Structure of Pd(OAc)_(2) with Halide Additives

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Chinese Journal of Chemistry 2022年第8期40卷 895-901页

作者： Liwei Wang dali Yang Hesham Alhumade Hong Yi Xiaotian Qi Aiwen Lei Institute for Advanced Studies(IAS) College of Chemistry and Molecular SciencesEngineering Research Center of Organosilicon Compounds&Materials(Ministry of Education)Wuhan UniversityWuhanHubei 430072China King Abdulaziz University JeddahSaudi Arabia Department of Chemical andMaterials Engineering Facultyof EngineeringCenter of Research Excellence in Renewable Energy andPowerSystemsKingAbdulaziz UniversityJeddah21589Saudi Arabia

Mechanistic studies of the palladium catalyst activation with halide additives are of great importance to palladium *** this work,XAFS spectroscopy and cyclic voltammetry were utilized to study real structures of Pd(OAc)2 in solution with different inorgan-ic halogen *** results demonstrate that Pd maintained+2 in the presence of excessive LiCl,LiBr,ZnCl_(2),ZnBr_(2),and *** results of EXAFS spectra revealed that the Pd's first shell is replaced by halogen partially or completely depending on the hal-ogen *** calculations were conducted to identify the most reliable solvated *** combined experimental and computational studies elucidate the critical role of inorganic halide additives in Pd chemistry.

关键词： Palladium Structure Halides X-ray absorption spectroscopy(XAS) Density functional calculation

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基于文献计量学的菟丝子研究现状及热点分析

中国中医药现代远程教育 2024年第4期22卷 82-86页

作者：蔡沓栗林罡李大建张丽萍福州市皮肤病防治院制剂室福建福州350025 深圳微芯生物科技股份有限公司广东深圳518057

目的了解菟丝子的研究现状及热点,展望其发展趋势。方法采用文献计量学研究方法,结合EndNote X9.1、VOSviewer软件对2001年—2021年万方数据知识服务平台、中国知网(CNKI)中菟丝子相关中文文献进行分析。结果菟丝子中文文献发文量在2... 详细信息

目的了解菟丝子的研究现状及热点,展望其发展趋势。方法采用文献计量学研究方法,结合EndNote X9.1、VOSviewer软件对2001年—2021年万方数据知识服务平台、中国知网(CNKI)中菟丝子相关中文文献进行分析。结果菟丝子中文文献发文量在2008年—2014年有增长,其中菟丝子的防治与栽培、混伪品的鉴别、有效成分的测定、黄酮类和多糖类成分的药理活性研究以及提取物抗衰老、抗细胞凋亡、生殖影响等研究为热点聚类。近几年研究热点为菟丝子多成分的指纹图谱或特征图谱的研究、网络药理学的分析等。结论作为传统中药的菟丝子仍具有巨大的探索空间。

关键词：菟丝子文献计量学研究热点

Biocompatibility of Surface-Modified Biphasic Calcium Phosphate/Poly-L-Lactide Biocomposite in vitro and in vivo

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Journal of Materials Science & Technology 2010年第8期26卷 754-758页

作者： Weizhong Yang Guangfu Yin dali Zhou Jianwen Gu Yadong Li Hujun Zhang College of Materials Science and Engineering Sichuan University Chengdu 610064 China Chengdu Military General Hospital Chengdu 610083 China

The biocompatibility of surface-modified biphasic calcium phosphate （mBCP）/poly-L-Lactide （PLLA） biocomposite was investigated through a series of experiments in vitro and in vivo. Acute toxicity and short term systemic toxicity experiments revealed no toxicity of the materials. Hemolysis assay indicated the good blood compatibility of the composite. In cytotoxicity assay, L929 mouse fibroblasts could well differentiate and proliferate. Animal experiments in vivo *** by implanting the materials into rabbits muscle for 8 weeks. The decreasing of inflammatory cells, the building of fibrous tissue layer as well as the growing of blood cells into materials indicated the nontoxicity of the composite. Based on the experiment results, surfacemodified BCP/PLLA biocomposite is proven to have superior biocompatibility, which would be a promising bone repairing material.

关键词： Biocompatibility Biphasic calcium phosphate (BCP) Poly-L-Lactide (PLLA)biocomposite

Design, synthesis and in vitro antitumor evaluation of novel diaryl urea derivatives bearing sulfonamide moiety

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Science China Chemistry 2013年第11期56卷 1564-1572页

作者： LUO Can TANG Ke LI Yan YIN dali CHEN XiaoGuang HUANG HaiHong Beijing Key Laboratory of Active Substance Discovery and Druggability Evaluation Institute of Materia Medica Peking Union Medical College & Chinese Academy of Medical Sciences

A novel series of diaryl urea derivatives bearing sulfonamide moiety have been designed and synthesized. Their in vitro antitumor effect against human cancer cell lines MX-1, A375, HepG2, Ketr3 and HT-29 was screened and evaluated by the standard MTT assay with sorafenib as the positive control. Some of the compounds showed significant inhibitory activity against multiple cell lines compared to sorafenib. In particular, 2,6-dimethyl-4-{6-[3-（4-chloro-3-（trifluoromethyl）phenyl）urealnaphthalen- 2-yllsulfonyl morpholine （10d） was found to be the most potent against A375, HepG2 and Ketr3 with ICs0 values of 0.65-0.97 μmol/L, which were 5-20-fold more potent than sorafenib. Compound 10d emerged as a valuable lead for further optimization.

关键词： diaryl urea derivatives sulfonamide sorafenib antitumor activity

Image Magnification Using Fractional order Level Set Reconstruction 25th

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Image Magnification Using Fractional order Level Set Reconst...

A Bioorthogonal-Activated Fluorescence Turn-On Probe Based on Nitrone-Modified 1,8-Naphthalimide for Live-Cell Imaging

第25届中国控制与决策会议

作者： Shenshen Sun Dingyu Xue dali Chen College of Information Science and Engineering Shenyang University School of Information Science and Engineering Northeastern University

ISBN: (纸本)9781467355339

A new fractional order MCM function is proposed for image magnification in this paper. The traditional MCM function of integer order is generalized to fractional order, through introducing a fractional order term to the energy function of level set models. The fractional order level set model is to solve a typical fractional order variational problem through deducing an fractional order Euler-Lagrange equation for minimizing the modified energy function. The equations are actually complicated partial differential equations （PDE） of fractional order and a numerical implementation based on GL fractional derivative definition is used to solve it. Theoretic analysis reveals that the proposed fractional order MCM function can be viewed as generalization of the traditional MCM function. At last, the proposed fractional order MCM function is implemented and tested on a series of contrary experiments, which demonstrate that fractional order MCM function can obtain better image magnification results than the corresponding integral one.

关键词： Level set fractional order partial differential equations fractional order MCM function image magnification.

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Chinese Journal of Chemistry 2022年第2期40卷 209-214页

作者： Yu Teng Hong Yang Xiang Li Yongcheng Wang dali Yin Yulin Tian State Key Laboratory of Bioactive Substances and Function of Natural Medicine Beijing Key Laboratory of Active Substances Discovery and Drugability EvaluationInstitute of Materia MedicaPeking Union Medical College and Chinese Academy of Medical Sciences1st Xian Nong Tan StreetBeijing 100050China

A nitrone-modified 1,8-naphthalimide was desig ned as a novel bioorthog on alactivated turn-on probe based on strain-promoted alkyne-nitrone cycloadditio n(SPANC).The bioorthog onal cycloadducts were subseque ntly tran sformed into fluoresce nt rearra nge-ment products by photo-accelerati on,which exhibited sign ificant fluoresce nee enhan ceme nt,large stokes shift,and high fluores-cence qua ntum *** calculati ons were performed to elucidate the fluoresce nee OFF-ON mecha *** fluoroge nic strategy was successfully applied to labeling of proteins and visualizing mitochondria in live cells in real time.

关键词： Bioorthogonal reaction Fluorescence Naphthalimide Imaging agents Cycloaddition