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Exploring the limited use of transdermal medications in psychiatry:Challenges and potential solutions

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World Journal of Methodology 2024年第4期14卷 18-22页

作者： mandeep Kaur Meera Patel Elizabeth Monis Department of Psychiatry and Behavioral Health Cape Fear Valley Medical CenterFayettevilleNC 28305United States

Transdermal medications are an useful yet underutilized tool in the field of *** numerous advantages of using this route of medication delivery,transdermal medications remain less popular compared to other routes of medication administration such as oral and intramuscular routes in the management of various psychiatric *** this editorial,we examine the advantages of transdermal medications with a brief overview of transdermal being used in psychiatry and other medical *** discuss the factors that play a role in their limited usage in *** highlight certain patient categories who can specifically benefit from them and discuss potential solutions that can broaden the perspective of treating clinicians making this an intriguing avenue in the field of psychiatry.

关键词： Transdermal medications Psychiatric medications Psychopharmacology Treatment options Potential solutions

Synthesis and photoluminescent performance of novel europium(Ⅲ) carboxylates with heterocyclic ancillary ligands

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Rare Metals 2022年第4期41卷 1342-1352页

作者： Priyanka dhankhar Rekha Devi Sushma Devi Sangeeta Chahar mandeep Dalal V.B.Taxak S.P.Khatkar Priti Boora Department of Chemistry Maharshi Dayanand UniversityRohtak 124001India

Five novel europium(Ⅲ)complexes with 2-[4-(dibutylamino)-2-hydroxybenzoyl]benzoic acid(DAHB)as primary ligand and bathophenanthroline(batho),2,2’-bipyridyl(bipy),5,6-dimethyl-1,10-phenanthroline(dmph),1,10-phenanthroline(phen)as ancillary ligands were syn-thesized via solution precipitation *** structural formulae of synthesized complexes were speculated to be Eu(DABH)_(3)·2H_(2)O(C1),Eu(DABH)_(3)·batho(C2),Eu(DABH)_(3)·bipy(C3),Eu(DABH)_(3)·dmph(C4)and Eu(DABH)_(3)·phen(C5)by elemental analysis,infrared spectroscopy and proton nuclear magnetic resonance spec-troscopy(^(1)H-NMR).The photoluminescent properties and thermal stability of the complexes were investigated by photoluminescent spectroscopy and thermogravimetric analysis(TG-DTG),*** Commission Inter-nationale de I’Eclairage(CIE)color coordinates,Judd–Ofelt intensity parameter(Ω_(2)),total quantum yield,intrinsic quantum efficiency and energy transfer dynamics of com-plexes were also *** excitation spectra of com-plexes are extended up to visible *** complexes exhibit characteristic photoemission of Eu^(3+)metal ion with high color purity in red region attributed to efficient energy transfer from ligand to metal *** replacement of water molecules from coordination sphere of europium ion by ancillary ligands results in enhancement of luminescent properties of the C2–C5 complexes,indicating that ancillary ligands act as additional light harvesting centers in sensiti-zation *** thermal studies show that these complexes are suitable for meeting the requirement of temperature for fabrication of OLEDs devices.

关键词： Photoluminescence Europium Sensitization Aromatic carboxylic acid Energy transfer dynamics

Support Vector Machine Based Handwritten Hindi Character Recognition and Summarization

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Computer Systems Science & Engineering 2022年第10期43卷 397-412页

作者： Sunil dhankhar Mukesh Kumar Gupta Fida Hussain Memon Surbhi Bhatia Pankaj Dadheech Arwa Mashat Department of Computer Science&Engineering Swami Keshvanand Institute of TechnologyManagement&GramothanJaipurRajasthan302017India Department of Electrical Engineering Sukkur IBA UniversityPakistan Department of Mechatronics Engineering Jeju National UniversityJeju63243Korea Department of Information Systems College of Computer Science and Information TechnologyKing Faisal UniversitySaudi Arabia Faculty of Computing&Information Technology King Abdulaziz UniversityRabigh21911Saudi Arabia

In today’s digital era,the text may be in form of *** research aims to deal with the problem by recognizing such text and utilizing the support vector machine(SVM).A lot of work has been done on the English language for handwritten character recognition but very less work on the under-resourced Hindi language.A method is developed for identifying Hindi language characters that use morphology,edge detection,histograms of oriented gradients(HOG),and SVM classes for summary *** rank employs the summary to extract essential phrases based on paragraph position,phrase position,numerical data,inverted comma,sentence length,and keywords *** primary goal of the SVM optimization function is to reduce the number of features by eliminating unnecessary and redundant *** second goal is to maintain or improve the classification system’s *** experiment included news articles from various genres,such as Bollywood,politics,and *** proposed method’s accuracy for Hindi character recognition is 96.97%,which is good compared with baseline approaches,and system-generated summaries are compared to human *** evaluated results show a precision of 72%at a compression ratio of 50%and a precision of 60%at a compression ratio of 25%,in comparison to state-of-the-art methods,this is a decent result.

关键词： Support vector machine(SVM) optimization precision Hindi character recognition optical character recognition(OCR) automatic summarization and compression ratio

Correlation of human immunodeficiency virus and antiretroviral therapy with cardiac disorders

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Global Health Journal 2023年第3期7卷 130-136页

作者： Riya Sharma mandeep kaur Department of Pharmacy Practice ISF College of PharmacyMogaPunjab 142001India

The occurrence of cardiovascular illness in the human immunodeficiency virus(HIV)community is increasing,with a particular focus on coronary heart *** infected with HIV have a higher risk of myocardial infarction compared to the general population in modern countries due to the development of effective antiretroviral medications and increased life *** not receiving highly active antiretroviral therapy(ART)may experience common cardiac consequences,including myocarditis,dilated cardiomyopathy,endocarditis,pulmonary hypertension,pericardial effusion,and cardiotoxicity associated with non-antiretroviral *** the use of highly active ART,continuing immune activation and systemic inflammation seem to play a central role in this *** studies suggest that protease inhibitors might negatively impact the progression of HIV-related heart failure(HF),which complicates the determination of the best therapy strategy for HIVassociated *** objective of this review is to examine the pathophysiology and correlation of various antiretroviral drugs leading to HIV-associated ***,we explore the causes of HIV-associated atherosclerotic cardiovascular disease,including the high frequency of classic cardiovascular risk factors in HIVinfected patients,as well as HIV-related factors like the use of ART and chronic inflammation despite successful treatment of HIV *** studies have revealed that individuals living with HIV/acquired immune deficiency syndrome frequently experience *** conclusion,despite advancements in HIV care,HIV-infected individuals continue to face an increased risk of HIV-associated cardiomyopathy and *** research is necessary to comprehend the underlying causes and develop effective treatments for cardiovascular disease in this *** also discuss the currently available therapeutic options and ongoing research to mitigate the risk of cardiovascular disease and

关键词： Antiretroviral therapy Cardiac disorders Myocardial infarction cardiomyopathy Heart failure HIV/AIDS Myocardial infarction

Experimental investigation into the effects of Argemone biodiesel/diesel blends on cyclic variations in a multi-cylinder CRDI engine

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Clean Energy 2023年第2期7卷 363-374页

作者： Abhinav Sharma Prem Kumar Sarbjot Singh Sandhu mandeep Singh Department of Mechanical Engineering Dr B R Ambedkar National Institute of TechnologyJalandhar-144011PunjabIndia

Internal combustion engines suffer from high cyclic variations that result in higher emissions,lower efficiency,higher fuel consump-tion and poor *** purpose of this study is to investigate how Argemone mexicana biodiesel(AGB)/diesel blended fuels affect the cyclic variability of combustion parameters such as maximum cylinder pressure(Pmax)and indicated mean effective pressure(IMEP)in a four-cylinder turbocharged intercooled common-rail direct injection engine under various engine loading *** chemical and physical properties of AGB produced from *** oil were measured and compared according to the ASTM D6751 *** various volumetric ratios,AGB and diesel fuel were blended as D100,AB10(10%AGB+90%D100),AB20(20%AGB+80%D100)and AB30(30%AGB+70%D100).The IMEP and Pmax time-series data were collected over 200 consecutive cycles at low,partial and high engine loads at a constant engine speed of 2000 *** coefficients of variation(COV)of combustion parameters(Pmax and IMEP)were measured for different AGB/diesel blends and found to be within acceptable *** results show that COV_(Pmax) and COV_(IMEP) decrease as the engine load *** was observed that at low load,AB10 has the lowest COV(Pmax,IMEP),and at partial and high load,AB20 has the lowest COV(Pmax,IMEP)among all the blends.

关键词： indicated mean effective pressure cyclic variations biodiesel diesel engine Argemone mexicana biodiesel

Two-level supply chain models with imperfect quality items when demand influences price and marketing promotion

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Journal of Management Analytics 2022年第4期9卷 480-495页

作者： Rita Yadav Sarla Pareek mandeep Mittal Mahesh Kumar Jayaswal Department of Mathematics and Statistics Banasthali VidyapithBanasthaliIndia Department of Mathematics Amity Institute of Applied SciencesAmity University Uttar PradeshNoidaIndia

The present paper studies a supply chain model with items that are of imperfect quality and with the assumption that end demand is responsive to price and promotion *** seller delivers items to the buyer in a *** an inspection process,it is observed that few articles produced are not of perfect *** defects might be the result of common operations or static *** defective items are then collected and are sold at a lower/discounted *** this paper,supply chain models are developed to approve the interaction among the players,in the supply chain *** interaction between the players is demonstrated by non-cooperative and cooperative game theoretical *** non-cooperative approach,optimal solutions are attained by game theoretic approaches named as Seller–Stackelberg and Buyer–*** the cooperative approach,a Pareto efficient solution is *** the last,numerical illustrations with sensitivity scrutiny are presented to support the theory of the present paper.

关键词： game theory imperfect quality items supply chain co-operative game non-cooperative games

Entropically favoured through space charge transfer‘lighted’photosensitizing assemblies for‘metal free’regulated photooxidation of alcohols and aldehydes

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Aggregate

Aggregate 2022年第2期3卷 143-153页

作者： Gurpreet Kaur Harpreet Kaur mandeep Kaur Manoj Kumar Vandana Bhalla Department of Chemistry Centre of Advance Studies-IIGuru Nanak Dev UniversityAmritsarIndia

Strong acceptor-weak acceptor system FN-TPy has been designed and synthesized,which undergoes solvent dependent self-assembly in mixed aqueous media to generate through space intermolecular charge transfer *** as-prepared entropically favoured assemblies of FN-TPy exhibit excellent photostability and photosensitizing properties in the assembled state to activate aerial oxygen for efficient generation of reactive oxygen species through Type-I and Type-II *** FN-TPy exhibits excellent potential for regulated oxidation of alcohols and aldehydes under mild reaction conditions(visible light irradiation,aqueous media,room temperature)using aerial oxygen as the‘oxidant’.The present study demonstrates the potential of FN-TPy assemblies to catalyse controlled oxidation of benzyl alcohol to benzoic acid.

关键词： aggregated assemblies molecular oxygen activation oxidations photosensitizer through space charge transfer

Inkjet Printed Metamaterial Loaded Antenna for WLAN/WiMAX Applications

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Computers, Materials & Continua 2022年第5期71卷 2271-2284页

作者： Farhad Bin Ashraf Touhidul Alam Md Tarikul Islam mandeep Jit Singh Norbahiah Binti Misran Mohammad Tariqul Islam Department of Electrical Engineering Polytechnique MontréalMontréalQC H3T 1J4Canada Space Science Centre(ANGKASA) Institute of Climate Change(IPI)Universiti Kebangsaan MalaysiaBangi43600SelangorMalaysia Department of Electrical Electronic and Systems EngineeringFaculty of Engineering and Built EnvironmentUniversiti Kebangsaan MalaysiaMalaysia

In this paper,the design and performance analysis of an Inkjetprinted metamaterial loaded monopole antenna is presented for wireless local area network(WLAN)and worldwide interoperability for microwave access(WiMAX)*** proposed metamaterial structure consists of two layers,one is rectangular tuning fork-shaped antenna,and another layer is an inkjet-printed metamaterial *** metamaterial layer is designed using four split-ring resonators(SRR)with an H-shaped inner structure to achieve negative-index metamaterial *** metamaterial structure is fabricated on low-cost photo paper substrate material using a conductive inkbased inkjet printing technique,which achieved dual negative refractive index bands of 2.25–4.25 GHz and 4.3–4.6 *** antenna is designed using a rectangular tuning fork structure to operate at WLAN and WiMAX *** antenna is printed on 30×39×1.27 mm3 Rogers RO3010 substrate,which shows wide impedance bandwidth of 0.75 GHz(2.2 to 2.95 GHz)with 2 dB realized gain at 2.4 *** integrating metamaterial structure,the impedance bandwidth becomes 1.25 GHz(2.33 to 3.58 GHz)with 2.6 dB realized gain at 2.4 *** antenna bandwidth and gain have been increased using developed quad SRR based metasurface by 500 MHz and 0.6 dBi ***,the proposed quad SRR loaded antenna can be used for 2.4 GHz WLAN bands and 2.5 GHz WiMAX *** contribution of this work is to develop a cost-effective inject printed metamaterial to enhance the impedance bandwidth and realized the gain of a WLAN/WiMAX antenna.

关键词： Metamaterial epsilon negative antenna split ring resonator WiMAX WLAN

Computational Investigation of Multiband EMNZ Metamaterial Absorber for Terahertz Applications

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Computers, Materials & Continua 2022年第5期71卷 3905-3920页

作者： Ismail Hossain Md Samsuzzaman Mohd Hafiz Baharuddin Norsuzlin Binti Mohd Sahar mandeep Singh Jit Singh Mohammad Tariqul Islam Space Science Center Universiti Kebangsaan Malaysia43600UKM BangiSelangorMalaysia Department of Computer and Communication Engineering Faculty of Computer Science and EngineeringPatuakhali Science and Technology UniversityBangladesh Department of Electrical Electronic and Systems EngineeringFaculty of Engineering and Built EnvironmentUniversiti Kebangsaan MalaysiaMalaysia

This study presents an Epsilon Mu near-zero(EMNZ)nanostructured metamaterial absorber(NMMA)for visible regime *** resonator and dielectric layers are made of tungsten(W)and quartz(fused),where the working band is expanded by changing the resonator layer’s *** to perfect impedance matching with plasmonic resonance characteristics,the proposed NMMA structure is achieved an excellent absorption of 99.99%at 571 THz,99.50%at 488.26 THz,and 99.32%at 598 THz *** absorption mechanism is demonstrated by the theory of impedance,electric field,and power loss density distributions,*** geometric parameters are explored and analyzed to show the structure’s performance,and a near-field pattern is used to explain the absorption mechanism at the resonance frequency *** numerical analysis method describes that the proposed structure exhibited more than 80%absorbability between 550 and 900 *** Computer Simulation Technology(CST Microwave Studio 2019)software is used to design the proposed ***,CSTHFSS interference is validated by the simulation data with the help of the finite element method(FEM).The proposed NMMA structure is also exhibits glucose concentration sensing capability as *** the proposed broadband absorber may have a potential application in THz sensing,imaging(MRI,thermal,color),solar energy harvesting,light modulators,and optoelectronic devices.

关键词： Metamaterial absorber terahertz applications multiband EM near zero nanostructured visible regime applications