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Spindle cell lipoma of the mandibular mucogingival junction: a case report of unusual oral neoplasm

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International Journal of Oral Science 2014年第3期6卷 185-187页

作者： manal Abdulaziz Al Sheddi Ahmad Assari Hezekiah Mosadomi Department of Oral Medicine and Diagnostic Sciences College of Dentistry King Saud University Department of Oral and Maxillofacial Surgery and Diagnostic Sciences Riyadh Colleges of Dentistry and Pharmacy

Spindle cell lipoma（SCL） is a benign lipomatous neoplasm typically located in the posterior neck and back of older males. It presents as a well-circumscribed mass in the buccal mucosa, tongue, floor of the mouth or hard palate. There are only two case reports of SCL in the gingiva and alveolar ridge. Here, we report a case of SCL in the mandibular mucogingival junction of a 68-year-old male. Clinical,histopathological and immunohistochemical findings are presented. Although oral SCL is rare, it should be considered in the differential diagnosis of spindle cell neoplasms occurring in the oral cavity.

关键词： lipoma mucogingival junction oral cavity spindle cell lipoma

Enhanced Recovery after Cesarean Section (CS) versus Conventional Care in a Lower Middle-Income Country: A Randomized Controlled Trial

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Open Journal of Nursing 2022年第12期12卷 831-841页

作者： Atef Darwish manal Mustafa Entrsar Youness Bushra Al-Harazi Department of Obstetrics and Gynecology Faculty of Medicine Assiut University Assiut Egypt Department of Obstetrics and Gynecological Nursing Faculty of Nursing Assiut University Assiut Egypt Department of Obstetrics and Gynecological Nursing Faculty of Medicine and Health Sciences-Nursing Department Sana’a University Sanaa Yemen

Background: Enhanced recovery after surgery (ERAS) has been tested in a wide variety of surgeries with promising outcomes. However, there is a need for a standardized, evidence-informed approach to both the development of new ERAS Society guidelines, and the adaptation and revision of existing guidelines. Developing countries have limited resources and deserve every effort to improve economic status. Aim of the Study: to evaluate perinatal maternal outcomes of ERAS? versus routine care protocols in women undergoing elective cesarean section (CS) in a lower middle-income country with limited resources ranked as a third most country performing CS worldwide using a multidisciplinary team (MDT) management. Design: A prospective randomized Controlled Trial. Setting: Outpatient department (OPD) and labor ward at the Woman’s Health hospital, Assiut University, Egypt. Participants: Healthy pregnant women planned for elective CS (300 women) were randomly divided into a study group offered ERAS protocol and a control group offered regular care. Results: Repeat CS was the main indication of elective CS in both groups without significant difference (89 cases (59.3%) and 75 cases (50%) in both groups respectively). Other indications included cephalopelvic disproportion in 17 cases (11%) and 19 cases (12.6%), placenta previa in 28 (18.6%) and 34 (22.6%) cases, DM in 11 (7%) and 19 (12.6%) cases, and others in 5 (0.3%) and 3 (2%) cases in both groups respectively. The study group took much less time to eat and walk. It had significantly lower pain levels and postoperative problems, as well as much greater women’s satisfaction and a shorter hospital stay (p = 0.001). Conclusions: Collaboration of nursing, obstetricians and anesthesiologists is the cornerstone for a successful ERAS for CS. Significant better perinatal maternal outcomes encourage expansion of ERAS in lower middle-income countries with limited resources.

关键词： Nursing Cesarean Section Enhanced Recovery

The role of varicocele sclerotherapy in men with severe ol igo-astheno-teratozoos perm ia

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Asian Journal of Andrology 2011年第6期13卷 867-871页

作者： Mazen A Ghanem manal A Safan Ashraf A Ghanem Gert R Dohle Department of Urology Menoufiya University 3481 Shebin EI-Kom Egypt Department of Urology Erasmus MC 3000 CA Rotterdam The Netherlands Department of Clinica Biochemistry Menoufiya University 3481 Shebin EI-Kom Egypt Department of Gynaecology and Obstetrics Mansoura University 35515 Mansoura Egypt

The aim of this study was to verify the role of antegrade scrotal sclerotherapy for the treatment of varicoceles in infertile men with severe oligo-astheno-teratozoospermia （OAT）. The 59 patients with severe OAT in this study underwent antegrade scrotal sclerotherapy for the treatment of varicoceles. The outcome was assessed in terms of improvement in semen parameters and spontaneous conception rate. Semen parameters and reproductive hormones were evaluated before antegrade sclerotherapy （AS） and 6 months after AS. After an average follow-up time of 34.8_＋3.2 months, significant improvement was noted in the mean sperm concentration, motility and morphology in 36 patients （61%）. Spontaneous pregnancy occurred in nine couples （15%）. Six months after treatment, inhibin B levels were significantly higher （P〉0.04）, whereas follicle-stimulating hormone （FSH） levels were significantly lower （P〈0.001） than before treatment. Antegrade internal spermatic vein sclerotherapy can significantly improve seminal parameters and hormonal parameters in men with severe OAT and may even result in spontaneous pregnancy in couples who would otherwise be candidates for intracytoplasmic sperm injection （ICSI）.

关键词： infertility Inhibin B oligo-astheno-teratozoospermia sclerotherapy semen parameters varicocele

Cutaneous Symptoms Revealing M5 Acute Myeloid Leukemia: A Case Report

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Journal of Cancer Therapy 2022年第11期13卷 640-647页

作者： Sara Anane Ayad Ghanam Amal Bennani manal Azizi Noufissa Benajiba Pediatric Department Mohammed VI University Hospital Faculty of Medicine and Pharmacy Mohammed 1st University Oujda Morocco Anatomo Pathological Department Mohammed VI University Hospital Faculty of Medicine and Pharmacy Mohammed 1st University Oujda Morocco

Cutaneous presentation revealing acute myeloid leukemia (AML) is rare, and the prognosis is poor. We report a case of an 11-month-old male who presented with cutaneous lesions present as diffuse purplish papulo-nodular lesions, revealing M5 acute myeloid leukemia. Skin biopsy and immunohistochemical examination, combined with routine blood analysis and bone marrow examination, contributed to early diagnosis. However, despite intensive chemotherapy treatment, the prognosis was poor and death occurred during the first months of treatment.

关键词： Acute Myeloid Leukemia AML-M5 Skin Nodules Case Report Child

A Credit-Based Approach for Overcoming Free-Riding Behaviour in Peer-to-Peer Networks

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Computers, Materials & Continua 2019年第4期59卷 15-29页

作者： manal Hazazi Afnan Almousa Heba Kurdi Shiroq Al-Megren Shada Alsalamah College of Computer and Information Science King Saud UniversityRiyadh 11642Saudi Arabia Mechanical Engineering Department Massachusetts Institute of Technology(MIT)CambridgeMA 02139USA

The underlying premise of peer-to-peer(P2P)systems is the trading of digital resources among individual peers to facilitate file sharing,distributed computing,storage,collaborative applications and multimedia ***-called free-riders challenge the foundations of this system by consuming resources from other peers without offering any resources in return,hindering resource exchange among ***,immense effort has been invested in discouraging free-riding and overcoming the ill effects of such unfair use of the ***,previous efforts have all fallen short of effectively addressing free-riding behaviour in P2P *** paper proposes a novel approach based on utilising a credit incentive for P2P networks,wherein a grace period is introduced during which free-riders must reimburse *** contrast to previous approaches,the proposed system takes into consideration the upload rate of peers and a grace *** system has been thoroughly tested in a simulated environment,and the results show that the proposed approach effectively mitigates free-riding *** to previous systems,the number of downloads from free-riders decreased while downloads by contributing peers *** results also show that under longer grace periods,the number of downloads by fast peers(those reimbursing the system within the grace period)was greater than the number of downloads by slow peers.

关键词： Peer-to-peer network free-riding file sharing credit

Development of Functional Synbiotic Flavored Fermented Skim Milk Drinks Supplemented with Doum (Hyphaene thebaica L.) and Carob (Ceratonia siliqua) Fruits Powder for Nutritional, Antimicrobial and High Antioxidant Activities

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Food and Nutrition Sciences 2022年第11期13卷 878-905页

作者： manal Khider Khaled Abd El-Hameed Seliem Warda Mustafa Abdeltawab Ebid Dairy Department Faculty of Agriculture Fayoum University Fayoum Egypt Department of Food Science Faculty of Agriculture Fayoum University Fayoum Egypt

The present study was carried out to make new healthy synbiotic flavored fermented skim milk drinks (SFFSD) supplemented with either Doum (Hyphaene thebaica L.) or Carob (Ceratonia siliqua) fruits powder for nutritional, antioxidant and antimicrobial activities. The HPLC analysis showed higher phenolic and flavonoid content in Doum extract than that of Carob. The antimicrobial activity of the methanolic extracts of both Doum and Carob against foodborne pathogens showed that the most sensitive indicators were Bacillus cereus, C. albicans and S. aureus, followed by T. mentagrophyte and E. coli wherein, the diameter of clear zones was, 29, 27, 24, 23 and 13 mm, respectively. While no effect was noticed against Aspergillus flavus. On the other hand, the methanolic extract of Carob fruit exhibited only a weak antibacterial effect against B. cereus (20 mm). Six treatments of SFFSD were made using both Doum or Carob fruit powder as prebiotic and Lactobacillus paracasei as probiotic bacteria. The added levels from Doum were 2%, 4% and 6%, while that added from Carob were 5%, 10% and 15%. Adding Doum and Carob powder increased the containing of minerals;Ca, K, Mg and iron compared with control. Both viscosity and viability of L. paracasei for the SFFSD were increased with increasing the added levels from either Doum or Carob, compared with the control. Samples of SFFSD containing Carob powder, show superior sensory for all parameters and total score points during storage period, especially at a level of 10%. It seems evident that samples supplemented with Doum powder were also acceptable.

关键词： Antimicrobial Carob Fruits Doum Fruits Phenolic Compounds Prebiotic and Probiotic

Nurses’ Knowledge, Attitude, and Practice Regarding Personal Protective Equipment for the Prevention of COVID-19 in Public Hospitals Khartoum State Sudan 2022

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Open Journal of Nursing 2023年第3期13卷 181-195页

作者： manal Bilal Mohamed Fatma Elamin Hamid Mohamed Nazik Mohamed Abdalla Taha Faculty of Nursing Science Omdurman Islamic University Omdurman Sudan Department of Surgical Nursing Faculty of Nursing Science Omdurman Islamic University Omdurman Sudan Medical Nursing Faculty of Nursing Science Omdurman Islamic university Omdurman Sudan

Since December 2019, there had been a series of unexplained cases of pneumonia reported in Wuhan, China, and on 12 January 2020, the World Health Organization (WHO) named this new virus as the 2019 novel coronavirus (2019-nCoV). The Novel Coronavirus disease (COVID-19) is an emerging, rapidly changing global health challenge affecting all sectors, including the health sector. This study aimed to investigate nurses’ knowledge, attitudes, and practices regarding the prevention and control of COVID-19. Methods: This cross-sectional study was conducted among nurses in three public health hospitals in Khartoum state. A self-administered questionnaire was used. A total of 14 knowledge questions were adopted. There are 5 questions constructed for attitude. A total of 12 practice questions were used. Mean score of knowledge considers as follows when the mean more than 75% considers as good knowledge while this percent uses as good practice and poor practice respectively to analyze the mean score differences of knowledge, attitudes, and practices between the independent variables. Spearman correlation was used to assess the relationship between mean knowledge and attitude scores. Results: Of the 101 nurses approached, a total of 100 nurses responded (99.0% response rate). The mean age of the participants was 27.6 (SD 5.3) years, and the majority of the participants were male (293/434, 67.5%). The mean knowledge score was 1.01 (SD 0.100). The mean attitude score was 10.5 (SD 4.1), and 54.8% (238/434) of the participants had a good attitude toward COVID-19. The mean practice score was 1.4176 (SD 1.4176). There was a negative correlation between knowledge and attitude scores (P < -0.014) and between knowledge and practice scores (P < -0.081). Conclusions: The overall levels of knowledge and practice and attitude were good.

关键词： COVID-19 Knowledge Attitude Practice Nurses Public Hospitals Khartoum State Sudan

Identification of functional tumor necrosis factor-alpha promoter variants associated with Helicobacter pylori infection in the Sudanese population: Computational approach

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World Journal of Gastroenterology 2022年第2期28卷 242-262页

作者： Abeer Babiker Idris Alaa B Idris manal A Gumaa Mohammed Babiker Idris Amanda Elgoraish Mohamed Mansour Dalia Allam Bashir MO Arbab Nazar Beirag El-Amin M Ibrahim Mohamed A Hassan Department of Agricultural Science and Technology Institute of Natural and Applied SciencesErciyes UniversityKayseri 38039Turkey Department of Medical Microbiology Faculty of Medical Laboratory SciencesUniversity of KhartoumKhartoum 11111Sudan Department of Neurosurgery Ribat University HospitalKhartoum 11111Sudan BioMérieux Clinical and Application Advisor Al-Jeel Medical Co.Riyadh 11422Saudi Arabia Department of Epidemiology Tropical Medicine Research InstituteKhartoum 11111Sudan Department of Gastroenterology Ibn Sina Specialized HospitalKhartoum 11111Sudan Department of Gastroenterology Modern Medical CentreKhartoum 11111Sudan Biosciences College of HealthMedicine and Life SciencesBrunel UniversityLondon UB83PHUxbridgeUnited Kingdom Department of Translation Bioinformatics Detavax BiotechKayseri 38350Turkey

BACKGROUND Helicobacter pylori(***)is a ubiquitous bacterium that affects nearly half of the world’s population with a high morbidity and mortality *** within the tumor necrosis factor-alpha(TNF-A)promoter region are considered a possible genetic basis for this *** To functionally characterize the genetic variations in the TNF-A 5’-region(-584 to+107)of Sudanese patients infected with *** using in silico *** An observational study was carried out in major public and private hospitals in Khartoum state.A total of 122 gastric biopsies were taken from patients who had been referred for *** DNA was *** of the TNF-A-1030 polymorphism was performed using PCR with confronting two-pair primer to investigate its association with the susceptibility to *** infection in the Sudanese ***,Sanger sequencing was applied to detect single nucleotide polymorphisms in the 5’-region(-584 to+107)of TNF-A in ***-infected *** analyses were used to predict whether these mutations would alter transcription factor binding sites or composite regulatory elements in this region.A comparative profiling analysis was conducted in 11 species using the ECR browser and multiple-sequence local alignment and visualization search engine to investigate the possible ***,a multivariate logistic regression model was constructed to estimate odds ratios and their 95%confidence intervals for the association between TNF-A-1030,sociodemographic characteristics and *** *** were statistically significant if PA,-76)was located at the in silico-predicted promoter region(-146 to+10),and it was predicted to alter transcription factor b

关键词： 5’-region Promoter TNF-A Helicobacter pylori In silico analysis Sudan

Chewing gum for declining ileus and accelerating gastrointestinal recovery after appendectomy

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Frontiers of Nursing 2018年第4期5卷 277-284页

作者： manal Hamed Mahmoud Safaa Hussein Mohammad Medical-Surgical Nursing Faculty of Nursing Benha University Medical-Surgical Nursing Faculty of Nursing Zagazig University

Objective: Ileus usually occurs after abdominal surgery and is allied with complication and delays recovery. It is hypothesized that chewing gum reduces postoperative ileus by improving early recovery of gastrointestinal function. This study aimed to explore whether chewing gum after appendectomy accelerates the recovery of gastrointestinal ***: Randomized control trial was used in this study. This study was conducted in the General Surgery Department at Zagazig University Hospital. A total of 240 patients undergoing appendectomy were involved in this study; they were divided into the chewing sugar-free gum group(120) and the control group(120). Two tools were utilized in this study. Tool I: Structured Interviewing Schedule: part 1: assessment of personnel characteristics. Part 2: assessment of anthropometric measurements of the studied subjects as well as pre-and intraoperative indicators of them. Tool II: postoperative assessment sheet: assessed postoperative parameters of the intestinal function, occurrence of postoperative ileus, and related symptoms were assessed among studied ***: There were highly significant statistical differences in the time of resumption of gastrointestinal functions and postoperative ileus symptoms between the two groups(P<0.001), which was significantly shorter in the chewing gum group compared to the control ***: The use of chewing gum is a useful and cheap method that can be employed to cut down the time to recover and accelerate normalization of gastrointestinal function. Chewing sugar-free gum after abdominal surgery is recommended to be added to the protocol of nursing care in the surgery units as well as its involvement in the nursing curriculum.

关键词： appendectomy chewing gum gastrointestinal recovery ileus