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TOPLESS promotes plant immunity by repressing auxin signaling and is targeted by the fungal effector Naked1

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Plant Communications 2022年第2期3卷 92-111页

作者： Fernando Navarrete Michelle Gallei Aleksandra EKornienko Indira Saado mamoona khan Khong-Sam Chia Martin A.Darino Janos Bindics Armin Djamei Gregor Mendel Institute(GMI) Austrian Academy of Sciences(OEAW)Vienna BioCenter(VBC)Dr.Bohr-Gasse 31030 ViennaAustria Leibniz Institute of Plant Genetics and Crop Plant Research(IPK) OT GaterslebenCorrensstraße 306466 Stadt SeelandGermany Present address:Institute of Science and Technology Austria Am Campus 13400 KlosterneuburgAustria Present address:Institute of Molecular Biotechnology Dr.Bohr-Gasse 31030 ViennaAustria Present address:Institute of Crop Science and Resource Conservation University of BonnBonnGermany

In plants,the antagonism between growth and defense is hardwired by hormonal *** perception of pathogen-associatedmolecularpatterns(PAMPs)frominvadingmicroorganismsinhibits auxin signalingand plant ***,pathogens manipulate auxin signaling to promote disease,but how this hormone inhibits immunity is not fully *** maydis is a maize pathogen that induces auxin signaling in its *** characterized a *** effector protein,Naked1(Nkd1),that is translocated into the host *** its native ethylene-responsive element binding factor-associated amphiphilic repression(EAR)motif,Nkd1 binds to the transcriptional co-repressors TOPLESS/TOPLESS-related(TPL/TPRs)and prevents the recruitment of a transcriptional repressor involved in hormonal signaling,leading to the derepression of auxin and jasmonate signaling and thereby promoting susceptibility to(hemi)biotrophic pathogens.A moderate upregulation of auxin signaling inhibits the PAMP-triggered reactive oxygen species(ROS)burst,an early defense ***,our findings establish a clear mechanism for auxin-induced pathogen *** Nkd1 variants with increased expression or increased EAR-mediated TPL/TPR binding trigger typical salicylic-acid-mediated defense reactions,leading to pathogen *** implies that moderate binding of Nkd1 to TPL is a result of a balancing evolutionary selection process to enable TPL manipulation while avoiding host recognition.

关键词： topless auxin pattern-triggered immunity PTI effector maize Ustilago maydis

Towards Improving the Quality of Requirement and Testing Process in Agile Software Development:An Empirical Study

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Computers, Materials & Continua 2024年第9期80卷 3761-3784页

作者： Irum Ilays Yaser Hafeez Nabil Almashfi Sadia Ali mamoona Humayun Muhammad Aqib Ghadah Alwakid University Institute of Information Technology Pir Mehr Ali Shah Arid Agriculture UniversityRawalpindi46000Pakistan Department of Software Engineering College of Computer and Information SciencesJouf UniversityAl Jouf72388Saudi Arabia School of Arts Humanities and Social Sciences University of RoehamptonLondonSW155PJUK Department of Computer Science College of Computer and Information SciencesJouf UniversityAl Jouf72388Saudi Arabia

Software testing is a critical phase due to misconceptions about ambiguities in the requirements during specification,which affect the testing ***,it is difficult to identify all faults in *** requirement changes continuously,it increases the irrelevancy and redundancy during *** to these challenges;fault detection capability decreases and there arises a need to improve the testing process,which is based on changes in requirements *** this research,we have developed a model to resolve testing challenges through requirement prioritization and prediction in an agile-based *** research objective is to identify the most relevant and meaningful requirements through semantic analysis for correct change *** compute the similarity of requirements through case-based reasoning,which predicted the requirements for reuse and restricted to error-based ***,the apriori algorithm mapped out requirement frequency to select relevant test cases based on frequently reused or not reused test cases to increase the fault detection ***,the proposed model was evaluated by conducting *** results showed that requirement redundancy and irrelevancy improved due to semantic analysis,which correctly predicted the requirements,increasing the fault detection rate and resulting in high user *** predicted requirements are mapped into test cases,increasing the fault detection rate after changes to achieve higher user ***,the model improves the redundancy and irrelevancy of requirements by more than 90%compared to other clustering methods and the analytical hierarchical process,achieving an 80%fault detection rate at an earlier ***,it provides guidelines for practitioners and researchers in the modern *** the future,we will provide the working prototype of this model for proof of concept.

关键词： Requirement prediction software testing agile software development semantic analysis case-based reasoning

Enhancing Secure Development in Globally Distributed Software Product Lines: A Machine Learning-Powered Framework for Cyber-Resilient Ecosystems

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Computers, Materials & Continua 2024年第6期79卷 5031-5049页

作者： Marya Iqbal Yaser Hafeez Nabil Almashfi Amjad Alsirhani Faeiz Alserhani Sadia Ali mamoona Humayun Muhammad Jamal University Institute of Information Technology PMAS-Arid Agriculture UniversityRawalpindiPakistan Department of Software Engineering College of Computer and Information SciencesJouf UniversityAl Jouf72388Saudi Arabia Department of Computer Science College of Computer and Information SciencesJouf UniversityAl Jouf72388Saudi Arabia Department of Computer Engineering&Networks College of Computer and Information SciencesJouf UniversityAl Jouf72388Saudi Arabia Department of Information Systems College of Computer and Information SciencesJouf UniversitySakakaAl Jouf72388Saudi Arabia Department of Mathematics Pir Mehr Ali Shah Arid Agriculture UniversityRawalpindiPakistan

Embracing software product lines(SPLs)is pivotal in the dynamic landscape of contemporary software ***,the flexibility and global distribution inherent in modern systems pose significant challenges to managing SPL variability,underscoring the critical importance of robust cybersecurity *** paper advocates for leveraging machine learning(ML)to address variability management issues and fortify the security of *** the context of the broader special issue theme on innovative cybersecurity approaches,our proposed ML-based framework offers an interdisciplinary perspective,blending insights from computing,social sciences,and ***,it employs ML for demand analysis,dynamic feature extraction,and enhanced feature selection in distributed settings,contributing to cyber-resilient *** experiments demonstrate the framework’s superiority,emphasizing its potential to boost productivity and security in *** digital threats evolve,this research catalyzes interdisciplinary collaborations,aligning with the special issue’s goal of breaking down academic barriers to strengthen digital ecosystems against sophisticated attacks while upholding ethics,privacy,and human values.

关键词： Machine Learning variability management cybersecurity digital ecosystems cyber-resilience

Smart-City-based Data Fusion Algorithm for Internet of Things

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Computers, Materials & Continua 2022年第11期73卷 2407-2421页

作者： Jawad khan Muhammad Amir khan N.Z.Jhanjhi mamoona Humayun Abdullah Alourani Department of Computer Science IIC University of TechnologyPhnom PenhCambodia Department of Computer Science COMSATS University IslamabadAbbottabad Campus22060Pakistan School of Computer Science and Engineering SCETaylor’s UniversitySubang JayaSelangorMalaysia Department of Information Systems College of Computer and Information SciencesJouf Universityal-JoufKSA Department of Computer Science and Information College of Science in ZulfiMajmaah UniversityAl-Majmaah11952Saudi Arabia

Increasingly,Wireless Sensor Networks(WSNs)are contributing enormous amounts of *** the recent deployments of wireless sensor networks in Smart City infrastructures,significant volumes of data have been produced every day in several domains ranging from the environment to the healthcare system to *** wireless sensor nodes,a Smart City environment may now be shown for the benefit of *** Smart City delivers intelligent infrastructure and a stimulating environment to citizens of the Smart Society,including the elderly and ***,Quality of Service(QoS)and poor data performance are common problems in WSNs,caused by the data fusion method,where a small amount of bad data can significantly impact the total fusion *** our proposed research,a WSN multisensor data fusion technique employing fuzzy logic for event *** the new proposed Algorithm,sensor nodes will collect less repeated data,and redundant data will be used to increase the data’s overall *** network’s fusion delay problem is investigated,and a minimum fusion delay approach is provided based on the nodes’fusion waiting *** proposed algorithm performs well in fusion,according to the results of the *** a result of these discoveries,It is concluded that the algorithm describe here is effective and dependable instrument with a wide range of applications.

关键词： Internet of things data fusion wireless sensor network fuzzy inference system

A Compact Rhombus Shaped Antenna with Extended Stubs for Ultra-Wideband Applications

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Computers, Materials & Continua 2022年第11期73卷 2637-2650页

作者： Syed Misbah un Noor Muhammad Amir khan Shahid khan NZ Jhanjhi mamoona Humayun Hesham A.Alhumyan Department of Electrical Engineering IIC University of TechnologyPhnom PenhCambodia Department of Computer Science COMSATS University IslamabadAbbottabad Campus22060Pakistan Department of Electrical and Computer Engineering COMSATS University IslamabadAbbottabad Campus22060Pakistan School of Computer Science SCSTaylor’s UniversitySubang Jaya47500SelangorMalaysia 5Center for Smart Society 0 CSS5 Faculty of Innovation and TechnologyTaylor’s UniversitySubang Jaya47500Malaysia Department of Information Systems College of Computer and Information SciencesJouf UniversityAl-JoufKSA

Ultra-wideband(UWB)is highly preferred for short distance *** a result of this significance,this project targets the design of a compact UWB *** paper describes a printed UWB rhombusshaped antenna with a partial ground *** achieve wideband response,two stubs and a notch are incorporated at both sides of the rhombus design and ground plane *** excite the antenna,a simple microstrip feed line is *** suggested antenna is built on a 1.6 mm thick FR4 *** proposed design is very compact with overall electrical size of 0.18λ×0.25λ(14×18 mm2).The rhombus shaped antenna covers frequency ranging from 3.5 to 11 GHz with 7.5 GHz impedance *** proposed design simulated and measured bandwidths are 83.33%and 80%,*** pattern in terms of E-field and H-field are discussed at 4,5.5 and 10 GHz *** proposed design has 65%radiation efficiency and 1.5 dBi peak *** proposed design is simulated in CST(Computer Simulation Technology)simulator and the simulated design is fabricated for the measured *** simulated and measured findings are in close *** obtained results confirm the application of the proposed design for the ultra-wide band applications.

关键词： Ultra-wideband impedance bandwidth radiation pattern CST electrical size

Prediction of COVID-19 Cases Using Machine Learning for Effective Public Health Management

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Computers, Materials & Continua 2021年第3期66卷 2265-2282页

作者： Fahad Ahmad Saleh N.Almuayqil mamoona Humayun Shahid Naseem Wasim Ahmad khan Kashaf Junaid Department of Computer Sciences Kinnaird College for WomenLahore54000Pakistan Department of Information Systems College of Computer and Information SciencesJouf UniversitySakakaAljouf72341Saudi Arabia Division of Computer Science&Information Technology University of EducationLahore54000Pakistan School of Computer Science National College of Business Administration&EconomicsLahore54000Pakistan Department of Clinical Laboratory Sciences College of Applied Medical SciencesJouf UniversitySakakaAljouf72341Saudi Arabia

COVID-19 is a pandemic that has affected nearly every country in the *** present,sustainable development in the area of public health is considered vital to securing a promising and prosperous future for ***,widespread diseases,such as COVID-19,create numerous challenges to this goal,and some of those challenges are not yet *** this study,a Shallow Single-Layer Perceptron Neural Network(SSLPNN)and Gaussian Process Regression(GPR)model were used for the classification and prediction of confirmed COVID-19 cases in five geographically distributed regions of Asia with diverse settings and environmental conditions:namely,China,South Korea,Japan,Saudi Arabia,and *** environmental and non-environmental features were taken as the input dataset,and confirmed COVID-19 cases were taken as the output dataset.A correlation analysis was done to identify patterns in the cases related to fluctuations in the associated *** results of this study established that the population and air quality index of a region had a statistically significant influence on the ***,age and the human development index had a negative influence on the *** proposed SSLPNN-based classification model performed well when predicting the classes of confirmed *** training,the binary classification model was highly accurate,with a Root Mean Square Error(RMSE)of ***,the results of the regression analysis using the GPR technique with Matern 5/2 were highly accurate(RMSE=0.95239)when predicting the number of confirmed COVID-19 cases in an ***,dynamic management has occupied a core place in studies on the sustainable development of public health but dynamic management depends on proactive strategies based on statistically verified approaches,like Artificial Intelligence(AI).In this study,an SSLPNN model has been trained to fit public health associated data into an appropriate class,allowing GPR to predict the number of confir

关键词： Public health sustainable development artificial intelligence SARSCoV-2 shallow single-layer perceptron neural network binary classification gaussian process regression

Prediction Model for Coronavirus Pandemic Using Deep Learning

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Computer Systems Science & Engineering 2022年第3期40卷 947-961页

作者： mamoona Humayun Ahmed Alsayat Department of Information Systems College of Computer and Information SciencesJouf UniversityKSA Department of Computer Science College of Computer and Information SciencesJouf UniversityKSA

The recent global outbreak of COVID-19 damaged the world health systems,human health,economy,and daily life *** of the countries was ready to face this emerging health *** professionals were not able to predict its rise and next move,as well as the future curve and impact on lives in case of a similar pandemic situation *** created huge chaos globally,for longer and the world is still struggling to come up with any suitable *** the better use of advanced technologies,such as artificial intelligence and deep learning,may aid healthcare practitioners in making reliable COVID-19 *** proposed research would provide a prediction model that would use Artificial Intelligence and Deep Learning to improve the diagnostic process by reducing unreliable diagnostic interpretation of chest CT scans and allowing clinicians to accurately discriminate between patients who are sick with COVID-19 or pneumonia,and also empowering health professionals to distinguish chest CT scans of healthy *** efforts done by the Saudi government for the management and control of COVID-19 are remarkable,however;there is a need to improve the diagnostics process for better *** used a data set from Saudi regions to build a prediction model that can help distinguish between COVID-19 cases and regular cases from CT *** proposed methodology was compared to current models and found to be more accurate(93 percent)than the existing methods.

关键词： Artificial Intelligence(AI) deep learning(DL) COVID-19 pandemic

Cyber Security and Privacy Issues in Industrial Internet of Things

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Computer Systems Science & Engineering 2021年第6期37卷 361-380页

作者： NZ Jhanjhi mamoona Humayun Saleh NAlmuayqil School of Computer Science and Engineering(SCE) Taylor’s UniversitySelangorMalaysia Department of Information Systems College of Computer and Information SciencesJouf UniversityAl-JoufSaudi Arabia

The emergence of industry 4.0 stems from research that has received a great deal of attention in the last few ***,there has been a huge paradigm shift in the manufacturing and production ***,this poses a challenge for cybersecurity and highlights the need to address the possible threats targeting(various pillars of)industry ***,before providing a concrete solution certain aspect need to be researched,for instance,cybersecurity threats and privacy issues in the *** fill this gap,this paper discusses potential solutions to cybersecurity targeting this industry and highlights the consequences of possible attacks and countermeasures(in detail).In particular,the focus of the paper is on investigating the possible cyber-attacks targeting 4 layers of IIoT that is one of the key pillars of Industry *** on a detailed review of existing literature,in this study,we have identified possible cyber threats,their consequences,and ***,we have provided a comprehensive framework based on an analysis of cybersecurity and privacy *** suggested framework provides for a deeper understanding of the current state of cybersecurity and sets out directions for future research and applications.

关键词： Industrial Internet of things(IIoT) cybersecurity industry 4.0 cyber-attacks

Intrusion Detection Systems in Internet of Things and Mobile Ad-Hoc Networks

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Computer Systems Science & Engineering 2022年第3期40卷 1199-1215页

作者： Vasaki Ponnusamy mamoona Humayun NZJhanjhi Aun Yichiet Maram Fahhad Almufareh Faculty of Information and Communication Technology Universiti Tunku Abdul RahmanKamparMalaysia Department of Information Systems College of Computer and Information SciencesJouf UniversityAl-JoufSaudi Arabia School of Computer Science and Engineering(SCE) Taylor’s UniversitySelangorMalaysia

Internet of Things(IoT)devices work mainly in wireless mediums;requiring different Intrusion Detection System(IDS)kind of solutions to leverage 802.11 header information for intrusion ***-specific traffic features with high information gain are primarily found in data link layers rather than application layers in wired *** survey investigates some of the complexities and challenges in deploying wireless IDS in terms of data collection methods,IDS techniques,IDS placement strategies,and traffic data analysis *** paper’s main finding highlights the lack of available network traces for training modern machine-learning models against IoT specific ***,the Knowledge Discovery in Databases(KDD)Cup dataset is reviewed to highlight the design challenges of wireless intrusion detection based on current data attributes and proposed several guidelines to future-proof following traffic capture methods in the wireless network(WN).The paper starts with a review of various intrusion detection techniques,data collection methods and placement *** main goal of this paper is to study the design challenges of deploying intrusion detection system in a wireless *** detection system deployment in a wireless environment is not as straightforward as in the wired network environment due to the architectural *** this paper reviews the traditional wired intrusion detection deployment methods and discusses how these techniques could be adopted into the wireless environment and also highlights the design challenges in the wireless *** main wireless environments to look into would be Wireless Sensor Networks(WSN),Mobile Ad Hoc Networks(MANET)and IoT as this are the future trends and a lot of attacks have been targeted into these *** it is very crucial to design an IDS specifically to target on the wireless networks.

关键词： Internet of Things MANET intrusion detection systems wireless networks