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Practice of Glycemic Self-Monitoring in Diabetic Patients Followed at the Endocrinology Department of Donka University Hospital in Guinea

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Open Journal of Endocrine and Metabolic Diseases 2024年第2期14卷 33-38页

作者： mamadou Dian Mamoudou Diallo mamadou Mansour Diallo mamadou Chérif Diallo Alpha mamadou Diallo Kadija Dieng Abdoul Mazid Diallo Mody Abdoulaye Barry Kadidiatou Bah El’Hadj Zainoul Bah mamadou Alpha Diallo Ibrahima Condé Ousmane Kourouma Amadou Kaké Diabetology Unit Labe Regional Hospital Labé Guinea Faculty of Health Sciences and Techniques Gamal Abdel Nasser University of Conakry Conakry Guinea Endocrinology and Diabetology Department of Donka University Hospital Conakry Guinea Pediatrics Department of Donka University Hospital Conakry Guinea

Diabetes is a chronic pathology whose evolution is marked by micro and macroangiopathic complications. Optimal management can prevent the onset of complications and improve patients’ quality of life. Objectives: To determine the frequency of self-monitoring of blood glucose and to describe the errors found during self-monitoring in diabetic patients followed at the Endocrinology Department of Donka University Hospital in Guinea. Materials and methods: Descriptive cross-sectional study carried out between August and September 2020 involving diabetic patients followed up at the Endocrinology and Diabetology Department of the Donka National Hospital, CHU Conakry. Results: A total of 301 patients were enrolled, with an average age of 44.24 ± 21.01 years. 64.12% were female. Type 2 diabetes predominated in 64% of cases. The mean duration of diabetes was 6.14 ± 4.67 years, and 75.08% of patients lived in urban areas. Patients were on insulin in 36.21% of cases, insulin and biguanides (26.25%), hypoglycemic sulfonamide and biguanides (19.27%) and biguanides in 18.27% of cases. The frequency of self-monitoring of blood glucose was 43%, and 38% of patients made errors, notably reusing lancets (60%), not checking the expiration date (55.65%) and not washing their hands (48%). Conclusion: This study shows that self-monitoring of blood glucose is not performed by the majority of patients. Numerous errors were identified during blood glucose testing. Continued therapeutic education on the use of blood glucose meters will help empower patients and improve their quality of life.

关键词： Self-Monitoring of Blood Glucose Diabetes Conakry University Hospital

Determination of the Physico-Chemical Quality of the Waters of the Mamouwol River in the Urban Commune of Mamou, Republic of Guinea

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Journal of Environmental Science and Engineering(A) 2024年第4期13卷 111-121页

作者： mamadou Madaniou Sow mamadou Lamarana Souare Adama Moussa Sakho Alhassane Diami Diallo Laboratory Techniques Department Mamou Higher Institute of TechnologyMamou 063Republic of Guinea Chemistry Department Gamal Abdel Nasser UniversityConakryConakry 1147Republic of Guinea Guinea Waters Company Laboratory Almamya QuarterConakry BP:150Republic of Guinea

Water is one of the most important elements on which our daily lives depend,because of its many uses in various *** ensure that people have the right of access to water,the authorities must provide them with treated water that complies with the regulations and standards in force,particularly from a physico-chemical point of view,for all possible uses to avoid any health problems for *** aim of this research is to study the water in the Mamouwol River by measuring physico-chemical parameters:(1)pH,it varies from 5.2“Mam3”to 7.8“Mam4”in August 2021 then from 5.5“Mam3”to 7.7“Mam4”in March 2022,*** average of 6.9 for all sampling points;(2)Turbidity varies from 0.3 NTU“Mam1”to 26.3 NTU“Mam4”in August 2021,then from 0.3 NTU“Mam1”to 30.6 NTU“Mam4”in March 2022,*** average of 9.0 NTU for all sampling points;(3)Suspended matter,varying from 0.6 mg/L“Mam1”to 17.6 mg/L“Mam4”in August 2021,then from 0.6 mg/L“Mam1”to 30.0 mg/L“Mam4”in March 2022,*** average of 8.8 mg/L for all the sampling points“Mam1”,“Mam2”,“Mam3”and“Mam4”;(4)Dissolved oxygen,varying from 2.07 mg/L“Mam3”to 6.12 mg/L“Mam1”in August 2021,then from 1.05 mg/L“Mam3”to 5.05 mg/L“Mam1”in March 2022,*** average of 2.77 mg/L for all sampling points;(5)Nitrates vary from 1.32 mg/L“Mam1”to 3.96 mg/L“Mam4”in August 2021,then from 1.49 mg/L“Mam1”to 5.27 mg/L“Mam3”in March 2022,*** average of 5.53 mg/L for all sampling points;(6)Nitrites,varying from 0 mg/L“Mam1”and“Mam2”to 0.06 mg/L“Mam3”in August 2021,then from 0 mg/L“Mam1”and“Mam2”to 0.13 mg/L“Mam3”in March 2022,*** average of 0.03 mg/L for all sampling *** results show the presence of organic pollution.

关键词： River water Mamouwol physico-chemistry pollution

Prostatic Adenomectomy and Comorbidities: Frequency and Management at the Urology Department of the Ignace Deen National Hospital in Conakry

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Open Journal of Urology 2024年第4期14卷 217-226页

作者： Demba Cisse Alpha Oumar Barry Morlaye Fatoumata Bangoura Alimou Diallo mamadou Dian Bah Youssouf Keita Daouda Kanté Thierno mamadou Oury Diallo mamadou Bissiriou Bah mamadou Diawo Bah Abdoulaye Bobo Diallo Oumar Raphiou Bah Maitre-Assistant à la Facult&#233 des Sciences et Techniques de la Sant&#233 Universit&#233 Gamal Abdel Nasser de Conakry Conakry Guin&#233e

Goal: To determine the type of comorbidity and highlight the complications of adenomectomy and comorbidities. Material and Methods: This is a prospective, descriptive, cross-sectional study lasting six (6) months, from July 1, 2022 to December 31, 2022. Patients with BPH on comorbidity condition taken care of during the study period AND have agreed to participate in the study. Results: During our study, 49 cases of benign prostatic hypertrophy with comorbidities were collected, representing a frequency of 29%. The average age ranges for the patients were 43 - 70 years. The age group most affected was 70 to 79 years old (38.80%). Nocturnal urinary frequency was the main reason for consultation present in all our patients. The most frequent comorbidity was hypertension, i.e. 83.70%. The PSA rate between 4 and 10 was the most represented, i.e. 42.86%. The prostate volume was between 61 and 100 ml in 40.82% of patients. Histology showed that it was a benign adenomatous hypertrophy of the prostate in 85.70% and a prostatic adenomyoma in 14.29%. Trans-bladder adenomectomy alone was the most performed technique, i.e. 49%, followed by trans urethral resection of the prostate, i.e. 38.80%. Retention of urine after removal of the catheter was the most observed complication, i.e. 12.20%. Conclusion: Benign prostatic hypertrophy with comorbidities constitutes a frequent association. Because their presence can affect effectiveness and lead to complications.

关键词： Prostatic Hypertrophy Comorbidities Conakry University Hospital

Evaluation of the “Helicobacter pylori” Eradication Rate by Bismuth Quadritherapy or Concomitant Quadritherapy in Black Africans

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Open Journal of Gastroenterology 2024年第3期14卷 69-79页

作者： Diallo mamadou Sarifou Youssouf Oumarou Yaogo Abdoulatif Diallo Kadiatou Diallo Djenabou Wann Thierno Amadou Bah mamadou Lamine Yaya Diallo Ahmed Tidiane Diakhaby mamadou Kanté mamadou Aliou Sylla Djibril Hepato-Gastroenterology Department of the Donka National Hospital CHU Conakry Guinea Faculty of Health Sciences and Techniques Gamal Abdel Nasser University Conakry Guinea Internal Medicine Department Centre Hospitalier Universitaire Communautaire de Bangui Bangui Central African Republic Hepato Gastroenterology Department Angré University Hospital Abidjan Ivory Coast Department of Internal Medicine Donka National Hospital CHU Conakry Guinea

Introduction: Gastric infection by “Helicobacter pylori” remains a topical issue due to the evolving scientific data concerning its pathophysiology, the diseases and pathologies concerned, which now extend beyond the gastric or digestive sphere, and the treatment methods faced with the development of antibiotic resistance. Diagnosis of infection involves two inseparable aspects: identification of the bacterium itself and identification of the endoscopic and histological lesions caused by the bacterium. Objective: To evaluate the rate of eradication of Helicobacter pylori infection by bismuth quadruple therapy and concomitant treatment. Patients and methods: This was a prospective, cross-sectional, analytical study of all outpatients in the hepato-gastroenterology department during the study period from 1 January 2022 to 30 November 2023. All patients had undergone oeso-gastroduodenal fibroscopy and the diagnosis was made by histological examination of the gastric biopsy. Results: Our 113 patients comprised 68 men and 46 women. The sex ratio was 1.48 in favour of men. The mean age of our patients was 40.28 years, with extremes of 13 and 80 years. The clinical signs that prompted oeso-gastroduodenal fibroscopy were as follows: epigastralgia (69.91%), dyspepsia (14.16%), vomiting (7.08%), gastro-oesophageal reflux (6.19%) and altered general condition with weight loss (2.65%). The endoscopic lesions were: gastropathy (antral, fundic and diffuse: antro-fundial) (69.02%), bulbar ulcer (6.19%), gastric ulcer (5.31%). Helicobacter pylori infection was associated with chronic gastritis in all our patients;it was mild in 50%, moderate in 41% and severe in 9%. The eradication rate of Helicobacter pylori according to the treatment protocol used was 92.30% for bismuth quadruple therapy and 94.12% for concomitant quadruple therapy. Conclusion: The eradication rate of Helicobacter pylori in our study was 92.30% and 94.12% respectively for bismuth quadritherapy and concomitant the

关键词： “Helicobacter pylori” Eradication Quadritherapy Antibiotics Conakry

Prevalence of Diabetes and Hypertension on World Diabetes Day 2022 in Guinea

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Open Journal of Endocrine and Metabolic Diseases 2024年第1期14卷 1-6页

作者： mamadou Dian Mamoudou Diallo mamadou Mansour Diallo mamadou Chérif Diallo mamadou Alpha Diallo Alpha mamadou Diallo Mody Abdoulaye Barry Kadija Dieng Abdoul Mazid Diallo El’Hadj Zainoul Bah Kadidiatou Bah Amatoulaye Diallo Amadou Kaké Naby Moussa Baldé Oumou Baldé Unité de Diabétologie H&#244pital régional de Labé Labe Guinea Université de Conakry Conakry Guinea Service de Diabétologie CHU Donka Conakry Guinea Fondation de Lutte Contre le diabète et MNT Conakry Guinea

Introduction: Diabetes mellitus and hypertension are chronic diseases that are on the rise and pose a major public health problem among the priorities of healthcare systems. Objectives: Determine the prevalence of diabetes and hypertension and describe the sociodemographic characteristics of those screened. Materials and Methods: This was a cross-sectional study organized during a diabetes and hypertension screening campaign that took place in Conakry and five (05) inland regions on November 14, 2022. Results: 2050 people were screened, of whom 33.12% were housewives, the average age was 44.78 ± 16.23 years, and 55.27% were women. The screening sites were the city of Conakry 741 (36.15%), the Labé region 424 (20.68%), the N’Zérékoré region 298 (14.54%), the Faranah region 241 (11.75%), the Mamou region 210 (10.24%) and the Boké region 136 (6.63%). The prevalence of diabetes and hypertension were respectively 12.5% and 43.38% for the Boké region;6.19% and 16.19% for the Mamou region;3.02% and 21.81% for the N’Zérékoré region;31.95% and 13.69% for the Faranah region;9.67% and 20.28% for the Labé region;2.83% and 20.28% for the city of Conakry. Conclusion: Despite the limitations of the study duration, our series highlighted the high prevalence of diabetes and hypertension among people screened on World Diabetes Day 2022. Raising public awareness of a healthy lifestyle is essential for the prevention and control of diabetes and hypertension.

关键词： Prevalence Diabetes Hypertension

Ambulatory Radio Iodine Therapy in the Management of Hyperthyroidism in Africa: African Systematic Review and Perspectives in Burkina Faso

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Open Journal of Biophysics 2024年第1期14卷 1-10页

作者： Ki Thierry Romuald mamadou Salif Djigo Gora Thiaw Arsène Sanou Mamounata Zoungrana mamadou Mbodj Nuclear Medicine Department of the Yalgado OUEDRAOGO University Hospital Center in Ouagadougou Ouagadougou Burkina Faso Biophysics and Nuclear Medicine Laboratory of the Cheikh Anta DIOP University of Dakar Dakar Senegal Radiology Departement of the Bobo Dioulasso University Hospital Center in Bobo Dioulasso Bobo Dioulasso Burkina Faso

Introduction: In hyperthyroidism, selective irradiation of the thyroid gland with radioactive iodine is a radical treatment and an alternative to surgery. The aim of this review is to assess the medium-term efficacy of outpatient treatment of hyperthyroidism with iodine-131 in Africa. Methods: We identified the studies carried out in Africa on outpatient radiation therapy between 2016 and 2020. For each article included, we noted the country concerned and the year of publication, the numbers studied, the socio-demographic characteristics of the patients, the indications for radio iodine therapy, the dose administered, the results of the hormonal dosage 6 months after radiation. Results: 13 retrospective studies were included to constitute a total population of 925 patients. The average age was 40.77 years, the sex ratio of 1/5.4 with a clear female predominance. The 3 main etiologies of hyperthyroidism justifying outpatient radio iodine therapy were Graves’ disease (55.89%), toxic multinodular goiter (22.70%) and toxic adenoma (21.40%). The average dose of iodine 131 administered per course is 13.7 mCi. No short-and medium-term complications were reported. The radio iodine therapy was effective in 86.08% (n = 796) of the patients with extremes of 72% and 100%. Conclusion: Radio iodine therapy is effective in Africa. It is simple, inexpensive on an outpatient basis and well tolerated. The introduction of outpatient radio iodine therapy could improve the management of patients with hyperthyroidism in Burkina Faso.

关键词： Hyperthyroidism Outpatient Radio Iodine Therapy Africa

The Dual of the Two-Variable Exponent Amalgam Spaces (L^q(),l^p())(Ω)

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Journal of Applied Mathematics and Physics 2024年第2期12卷 383-431页

作者： Sambourou Massinanke Sékou Coulibaly mamadou Traore Departement d’Etudes et de Recherches de Mathématiques et d’Informatique Université des Sciences des Techniques et des Technolo-gies de Bamako Bamako Mali

Wiener amalgam spaces are a class of function spaces where the function’s local and global behavior can be easily distinguished. These spaces are ex-tensively used in Harmonic analysis that originated in the work of Wiener. In this paper: we first introduce a two-variable exponent amalgam space (Lq(),lp())(Ω). Secondly, we investigate some basic properties of these spaces, and finally, we study their dual.

关键词： Amalgam Spaces Variable Exponent Lebesgue Spaces Dual of a Vector Space

Grassland Pasture Composition and Quality in the Communes of Ziguinchor and Kolda, Senegal

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Open Journal of Ecology 2024年第9期14卷 683-705页

作者： Aly Diallo Saboury Ndiaye Arfang Ousmane Kemo Goudiaby Yaya Diatta mamadou Ndao mamadou Diamanka Gnima Manga Department of Agroforestry Faculty of Science and Technology Assane Seck University of Ziguinchor Ziguinchor Senegal

In Senegal, natural pasture plays a major role in feeding livestock. During the rainy season, herbaceous plants account for a large proportion of the fodder consumed by ruminants. In Casamance, the composition and quality of these grasses are poorly known and underexploited. In this context, the study aimed to improve the knowledge and valorisation of the herbaceous fodder of the South. Individual interviews were conducted and a questionnaire was sent to farmers living in Ziguinchor and Kolda. A floristic inventory with a phytosociological approach was also carried out. The data collected were processed using Excel and Sphinx software in order to differentiate and classify the herbaceous species eaten by the tail. The majority of respondents were Fulani (55.30%). most of whom ranged in age from 30 to 60. Livestock rearing came second (38.3%) after agriculture (40%) among the principal activities of the people surveyed. The floristic inventory identified 95 species in 68 genera and 22 families. Species of low and medium pastoral value dominate the herbaceous layer. The global rangeland quality index was 48.16% and the brute pastoral value was 54.77%. Thirteen species contributed 54.86% of the pastoral value of the grassland. The floristic composition of community rangelands showed the presence of a varied herbaceous fodder range. The combination of which will help to develop a table of nutritional values for the formation of equilibrated feed rations for farmed livestock.

关键词： Fodder Herbaceous Pasture Nutritional Assessment Livestock

Surgical Treatment of Upper Urinary Tract Lithiasis in Conakry

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Open Journal of Urology 2024年第9期14卷 487-498页

作者： Barry mamadou Madiou Diallo Thierno Oumar Sow Thierno Amadou Oury Diallo Thierno mamadou Oury Bah Ibrahima Bah mamadou Diao Cissé Demba Bah Oumar Raphiou Service dUrologie Hpital National Ignace Deen Universit Gamal Abdel Nasser de Conakry Conakry Guinea

Introduction: The management of urinary lithiasis in our settings has long been conventional surgery. The recent introduction of endoscopy of the upper urinary tract represents a major advance in our department. The aim was to contribute to the study of the treatment of lithiasis of the upper urinary tract in Conakry and to report on our initial experience of ureteroscopy in Conakry. Methodology: This is a prospective descriptive study lasting one year, from January 1 to December 31, 2022, carried out at the Urology Department of the Ignace Deen National Hospital and at the PERCHIN Urological Clinic. The study included all patients treated surgically for lithiasis of the upper urinary tract who met the selection criteria. Results: The study included 57 patients. The mean age was 30 years, with extremes of 20 and 73 years;the most represented age group was 31 to 40 years, followed by 20 to 30 years with 29.9% and 26.3% respectively. Males predominated in 36 cases (63.15%), with a M/F sex ratio of 1.71. Left-sided renal colic was the most common, at 75.43% (n=43), and right-sided renal colic at 40.35%, associated with digestive signs at 43.85%. 77.19% had normal creatinine levels before surgery, versus 22.81% with elevated creatinine levels, i.e. 15.78% improvement in renal function after surgery. Urinary tract infection was found in 47.36%, and Escherichia coli in 31.57%, followed by staphylococcus aureus in 8.77%. Overall, 82.45% of patients had organic damage to the kidneys or ureters. Right ureterohydronephrosis was noted in 56.14%, followed by left hydronephrosis in 26.32%. Open surgery was predominant in 52.63% of cases, with endoscopic surgery (URS) accounting for a significant 47.36% during the study period. The endoscopic treatment used was laser ureteroscopy. In our study, 73.68% underwent drainage of the upper excretory tract, including 64.91% with a JJ catheter. The average length of stay was 07 days, with extremes of 02 and 28 days, and 81.4% of patients

关键词： Urinary Lithiasis Surgical Treatment Ureteroscopy Upper Urinary Tract Conakry