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Agglomeration of coal and polyethylene mixtures during fixed‑bed co‑gasification

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International Journal of Coal science & Technology 2024年第2期11卷 91-100页

作者： Igor G.Donskoy Aleksandr N.Kozlov maksim V.Penzik Denis A.svishchev Lu Ding Melentiev Energy systems Institute Russian Federation130 Lermontova StreetIrkutskRussia 664033 East China University of science and Technology 130 Meilong RoadShanghai 200237China

The article presents the results of experimental studies on the gasification of mixtures of brown coal and polyethylene(up to 20 wt%fraction)in a laboratory *** work aims to study the agglomeration process during the heating and oxidation of the *** measurement results(gas composition,pressure drop)provide indirect information on the dynamics of thermal decomposition and structural changes in the fuel *** have shown that the interaction between polyethylene and a coal surface leads to the formation of dense agglomerates,in which the molten polymer acts as a *** form as a result of interfacial interactions between components and filtration flow *** hydrogen/carbon ratio in the solid residue of coal-polyethylene co-gasification increases from 0.07–0.2 to 1.11,indicating the formation of stable hydrocarbon compounds on the carbon *** conducted research makes it possible to identify possible interactions between chemical reactions and transfer processes that lead to agglomeration in mixtures of coal with polyethylene.

关键词： Coal Polyethylene Gasification Combustion Agglomeration

Empagliflozin alleviates podocytopathy and enhances glomerular nephrin expression in db/db diabetic mice

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World Journal of Diabetes 2020年第12期11卷 596-610页

作者： Vadim V Klimontov Anton I Korbut Iuliia s Taskaeva Nataliya P Bgatova maksim V Dashkin Nikolai BOrlov Anna s Khotskina Evgenii L Zavyalov Thomas Klein Laboratory of Endocrinology Research Institute of Clinical and Experimental Lymphology–Branch of the Institute of Cytology and GeneticsSiberian Branch of Russian Academy of Sciences(RICEL–Branch of IC&G SB RAS)Novosibirsk 630060Russia Laboratory of Ultrastructural Research Research Institute of Clinical and Experimental Lymphology–Branch of the Institute of Cytology and GeneticsSiberian Branch of Russian Academy of Sciences(RICEL–Branch of IC&G SB RAS)Novosibirsk 630060Russia Laboratory of Clinical Immunogenetics Research Institute of Clinical and Experimental Lymphology–Branch of the Institute of Cytology and GeneticsSiberian Branch of Russian Academy of Sciences(RICEL–Branch of IC&G SB RAS)Novosibirsk 630060Russia Center for Genetic Resources of Laboratory Animals Institute of Cytology and GeneticsSiberian Branch of Russian Academy of SciencesNovosibirsk 630090Russia Department of Cardiometabolic Diseases Research Boehringer Ingelheim Pharma GmbHBiberach 88397Germany

BACKGROUND Modern guidelines recommend sodium-glucose cotransporter-2(sGLT2)inhibitors as the preferred antihyperglycemic agents for patients with type 2 diabetes and chronic kidney ***,the mechanisms underlying the renal protective effect of sGLT2 inhibitors are not fully *** of podocytes and nephrin expression in glomeruli in db/db diabetic *** We treated 8-wk-old male db/db mice with EMPA(10 mg/kg/d)or vehicle for 8 ***-matched male db/+mice were included as non-diabetic *** of body composition,glycemic and lipid control,and plasma concentrations of leptin,insulin and glucagon were *** evaluated renal hypertrophy as kidney weight adjusted to lean mass,renal function as plasma levels of creatinine,and albuminuria as the urinary albumin-to-creatinine ratio(UACR).Renal structures were studied by light and transmission electron microscopy with a focus on mesangial volume and podocyte structure,*** nephrin and transforming growth factor beta(TGF-β)were assessed by *** severe obesity and hyperglycemia developed in db/db mice prior to the start of the experiment;increased plasma concentrations of fructosamine,glycated albumin,cholesterol,leptin,and insulin,and elevated UACR were *** expansion,glomerular basement membrane thickening,and increased area of TGF-βstaining in glomeruli were revealed in vehicle-treated *** was manifested by effacement of foot processes;nephrin-positive areas in glomeruli were *** decreased the levels of glucose,fructosamine and glycated albumin,UACR,kidney hypertrophy,mesangial expansion,glomerular basement membrane thickening,and glomerular TGF-βstaining,alleviated podocytopathy and restored glomerular staining of *** These data indicate that EMPA attenuates podocytopathy in experimental diabetic kidney *** anti-albuminuric effect of EMPA could be attributed to mitigation o

关键词： Diabetes Chronic kidney disease Albuminuria Podocyte sodium-glucose transporter 2 inhibitors Empagliflozin

Latitudinal and temporal shifts in the radial growth-climate response of siberian larch in the Polar Urals

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Journal of Mountain science 2018年第4期15卷 722-729页

作者： Vladimir V.KUKARsKIH Nadezhda M.DEVI Pavel A.MOIsEEV Andrey A.GRIGORIEV maksim O.BUBNOV Institute of plant and animal ecology UB RAs 8-Marta 202/3 620144 Ekaterinburg Russia

This paper presents a dendroclimatic analysis of siberian larch trees sampled along a latitudinal 260-km transect located in the Polar Urals,Russia. Three standardised chronologies were built over a length of 230–293 years using 79 individual tree-ring chronologies collected in the southern,middle and northern parts of the Polar *** correlation functions showed that the annual growth of the larches was mainly influenced by the air temperatures in June and July. The relative role of the temperatures increased from south to north. Daily air temperature data analysis revealed that the duration of the growing season in the northern part of the Polar Urals is 24 days less than that in the southern part. At the present time, air temperatures exceeded threshold of 8~℃, 5 days earlier than it did in the beginning of the 20 th century In response to the increase in the duration of the growing season and the changing winter conditions in the Polar Urals over the last 130 years, radial growth–temperature relationships in larches have weakened;this effect was strongly pronounced in the southern part of the Polar Urals.

关键词： Tree rings Dendroclimatilogy Larix sibirica Growing season Polar Urals

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基于Neuman故障源的实故障源模型

控制与决策 2000年第6期15卷 716-178页

作者：邓北星 s A lozhkin 清华大学电子工程系北京100084 莫斯科国立大学计算数学与控制论学院

基于 Neum an故障源 ,建立一种新的故障源模型 ,即具有实输入数组的故障源模型 (简称实故障源 )。利用概率分析方法研究在实故障源作用下 ,由函数单元构成的控制系统的可靠性 ,并给出了系统不可靠度的下界估计。可靠性估计定理给出的下... 详细信息

基于 Neum an故障源 ,建立一种新的故障源模型 ,即具有实输入数组的故障源模型 (简称实故障源 )。利用概率分析方法研究在实故障源作用下 ,由函数单元构成的控制系统的可靠性 ,并给出了系统不可靠度的下界估计。可靠性估计定理给出的下限值可作为工程实践中很有价值的参考点。

关键词：故障源不可靠度故障单元故障函数

Pre-recorded instructional audio vs. dispatchers' conversational assistance in telephone cardiopulmonary resuscitation: A randomized controlled simulation study

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World Journal of Emergency Medicine 2018年第3期9卷 165-171页

作者： Alexei Birkun maksim Glotov Herman Franklin Ndjamen Esther Alaiyex Esther Alaiye Temidara Adeleke sergey samarin Department of Anaesthesiology Resuscitation and Emergency MedicineMedical Academy named after S.I.Georgievsky of V.I.Vernadsky Crimean Federal University

BACKGROUND:To assess the effectiveness of the telephone chest-compression-only cardiopulmonary resuscitation(CPR)guided by a pre-recorded instructional audio when compared with dispatcher-assisted ***:It was a prospective,blind,randomised controlled study involving 109 medical students without previous CPR *** a standardized mannequin scenario,after the step of dispatcher-assisted cardiac arrest recognition,the participants performed compression-only resuscitation guided over the telephone by either:(1)the pre-recorded instructional audio(n=57);or(2)verbal dispatcher assistance(n=52).The simulation video records were reviewed to assess the CPR performance using a 13-item *** interval from call reception to the first compression,total number and rate of compressions,total number and duration of pauses after the first compression were also ***:There were no significant differences between the recording-assisted and dispatcher-assisted groups based on the overall performance score(5.6±2.2 vs.5.1±1.9,P>0.05)or individual criteria of the CPR performance *** recording-assisted group demonstrated provided(170.2±48.0 vs.156.2±60.7).CONCLUsION:When provided by untrained persons in the simulated settings,the compression-only resuscitation guided by the pre-recorded instructional audio is no less efficient than dispatcher-assisted *** studies are warranted to further assess feasibility of using instructional audio aid as a potential alternative to dispatcher assistance.

关键词： Cardiopulmonary resuscitation Cardiac arrest Dispatcher Telephone CPR Audio instructions Instructional aid

Liver blood supply after a modified Appleby procedure in classical and aberrant arterial anatomy

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World Journal of Gastrointestinal surgery 2013年第3期5卷 51-61页

作者： Vyacheslav I Egorov Roman V Petrov Michail V lozhkin Olga A Maynovskaya Natalia s starostina Natalia R Chernaya Ekaterina M Filippova Ostroumov 14~(th) City Hospital Department of Surgical Oncology Sechenov First State Medical University Department of General surgery Russian National Research Medical University Department of Abdominal surgery Herzen Institute of Oncology Department of Pathology Herzen Institute of Oncology Department of Radiological Herzen Institute of Oncology Department of Interventional Radiology Sklifosovsky Emergency Institute Department of Pathology VishnevskyInstitute of Surgery

Reported here are two cases of a modified Appleby operation for borderline resectable ductal adenocarcinoma of the pancreatic body, in one of which a R0 distal resection was attended to by excision, not only of the celiac axis, but also of the common and left hepatic arteries in the presence of arterial anatomic variation Michels, type Ⅷb. The possibility and avenues of the maintenance of the blood supply to the left hepatic lobe after surgical aggression of this kind are demonstrated employing computed tomography (CT) and 3-D CT angiography. Furthermore, both cases highlight all important worrisome aspects of pancreatic cancer resectability prediction.

关键词： Cancer Pancreas Management Pancreatectomy Distal pancreatectomy Vascular invasion Computed tomography Blood supply

synthesis of Ag/Ag<sub>2</sub>s Nanoclusters Resistive switches for Memory Cells

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Advances in Nanoparticles 2014年第1期3卷 1-4页

作者： Aleksey Nikolaevich Belov Olga Veniaminovna Pyatilova maksim Igorevich Vorobiev National Research University of Electronic Technology Zelenograd Russia

Resistive switching Ag/Ag2s nanoclusters were formed by sulphidation of melting-dispersed thin and continuous Ag films. The morphology, structure and electrical properties of the prepared clusters were characterized by scanning (sEM), transmitting electron (TEM), scanning resistance microscopes (sRM) and Raman scattering. Hysteretic resistive switching behavior was observed in the samples that were studied with ON/OFF switching voltage equal to 8 - 10 V respectively. simple empirical numerical simulation model, based on Deal-Grove model assumptions and mechanisms, for silver nanoclusters sulphidation process, was proposed.

关键词： silver sulphide Clusters Memory Cells sulphidation Deal-Grove Model

Gravity observation at continental borderlands (Russia, Primorie, Cape shults)

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Geodesy and Geodynamics 2017年第3期8卷 193-200页

作者： Vladimir Yu. Timofeev Eugenii N. Kalish Dmitriy G. Ardyukov maksim G. Valitov Anton V. Timofeev Yurii F. stus Ruslan G. Kulinich Dmitrii A. Nosov Igor s. sizikov Bernard Ducarme Trofimuk Institute of Petroleum Geology and Geophysics of siberian Branch Russian Academy of sciences 630090 Novosibirsk Akademika Koptyuga Prsp..3 Russian Federation Institute of Automatic and Electrometry of siberian Branch Russian Academy of sciences 630090 Novosibirsk Akademika Koptyuga Prsp. 1 Russian Federation Il'ichev Pacific Oceanological Institute Far Eastern Branch of Russian Academy of science 690041 Vladivostok Baltivskayast. 43 Russian Federation Georges Lemaotre Centre for Earth and Climate Research. Catholic University of Louvain Leuven Belgium

The paper is focused on different kinds of gravity results obtained in shults Cape Observatory for 2010 -2015. Gravity observation is interpreted together with GPs observation data which was obtained from 2012 to 2015 at the same station, The station is situated on Gamov peninsular （42.58° N, 131.15° E, Russia） at the coast of Japan sea, This region constitutes the eastern boundary of Eurasia. This major continental tectonic feature is associated with a seismic activity, high heat flow and anomalous thickness of earth＇s crust. The goal of the observation was the investigation of gravity variation with time and seismicity situation monitoring. Gravity observation was developed at special basement by absolute gravimeter （GABL type） and by spring gravimeter （sCINREX CG-5and gPhone type）. Tidal models were tested by results of observation with spring gravimeters. Reduction task was solved, as the experimental data received from different points of shults Cape Observatory was used. Applied reduction coefficient is 203.3 12Gal m l, and agrees with theoretical calculation. Next goal was studying structure of earth＇s crust by means of gravity models. Gravity anomaly varied from 30 mGal to 46 mGal, which also depend on difference reference system, Experimental results were used for testing of the structure of continental boundary, which also depends on the sea bottom flexion. Thickness of elastic layer was estimated from 12 km to 18 km by using different models.

关键词： Absolute and relative gravity observation space geodesy Reduction task for gravity structure models Crust

Determination of Candesartan and Hydrochlorothiazide in Human Plasma by HPLC Coupled with Mass spectrometry

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International Journal of Analytical Mass spectrometry and Chromatography 2014年第2期2卷 25-32页

作者： Olga s. Brushinina Roman V. Gurto maksim s. Timofeev Galina A. Frelikh Vladimir A. slepichev Elena A. Yanovskaya Natalia U. Polomeeva Yulya G. Zyuz’kova Vladimir V. Udut Federal Governmental Budgetary Institution “Research Institute of Pharmacology E.D. Goldberg’s Name” siberian Branch of the Russian Academy of Medical sciences Tomsk Russia Federal Governmental Budgetary Institution “Research Institute of Pharmacology E.D. Goldberg’s Name”siberian Branch of the Russian Academy of Medical sciences Tomsk Russia

Quantitative determination of hydrochlorothiazide (HCTZ) and candesartan (CDs) in human plasma in volunteers was performed using a sensitive, selective and specific LC-Ms method which has been developed and validated before the study. The study was performed by means of a liquid chromatograph shimadzu Prominence equipped with a mass spectrometer LCMs-2020. Analytical column PerfectBond ODs-HD HPLC-column 5 μm 250 × 3.0 mm with a pre-column cartridge PerfectBond ODs-HD 5 μm 10 × 3.0 mm, double source of ionization for LCMs-2020 (electrospray (EsI) and chemical (APCI)) and software Labsol LCMs V5 LCMs2020 systempack were used. The low limit of the quantitative determination for HCTZ and CDs made up 10 ng/ml. m/z for CDs 441.20—positive scan, m/z for HCTZ 295.90—negative scan. The method has been applied to a pharmacokinetic study of 12.5 mg HCTZ and 16 mg CDs tablet in healthy volunteers.

关键词： Candesartan Hydrochlorothiazide LC-Ms Pharmacokinetic