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Brain abscess:surgical experiences of 162 cases

Neuroimmunology and Neuroinflammation 2015年第1期2卷 153-161页

作者： Forhad Hossain Chowdhury Md Raziul haque mainul haque sarkar S.M.Noman Khaled Chowdhury Zahed Hossain Shisir Ranjan Department of Neurosurgery National Institute of Neurosciences and HospitalSher-e-Bangla NagarDhaka 1207Bangladesh Department of Neurosurgery Dhaka Medical CollegeDhaka 1000Bangladesh Department of Neonatolgy Dhaka Medical CollegeDhaka 1000Bangladesh

Aim:Brain abscess still poses a public health challenge in spite of the advent of modern neurosurgical techniques and ***,we present our surgical experiences and ultimate outcome in the management of brain ***:Totally,162 patients with proved brain abscess who underwent surgical treatment were included in this *** prospectively recorded data of surgical management of brain abscess and the ultimate outcome(by Glasgow outcome scale)were studied ***:Total number of cases was 162,of which 113 were acute pyogenic abscess while 49 were chronic *** the chronic abscess,29 were chronic pyogenic abscess,14 were tubercular,3 aspergillus,and 3 abscesses were in malignant brain *** acute cases,common clinical features were headache,fever,vomiting,focal deficit and *** chronic abscesses,common clinical features were mild to moderate headache and progressive focal ***-three(45.06%)patients had adjacent localized sinus,middle ear or cranial *** common predisposing factors included postneurosurgery,postpenetrating injury to brain,chronic suppurative otitis media,and congenital heart disease,infective endocarditis,sinusitis and sub optimum *** lobe involved in 30.2%cases,temporal lobe is next to *** time burr hole aspiration in 111(68.5%)cases,two or more times burr hole aspiration were done in 34(21%)*** culture was negative in 129(79.62%)*** number of death was 22(13.58%)*** resolution of abscess with complete recovery of preoperative neuro-deficit was seen in 80.86%cases and recovery with major neuro-deficit was observed in 5.55%*** is a significant association between Glasgow coma scale(GCS)on admission and mortality in brain ***:In most of the cases,pus culture did not yield growth of any causative *** was not directly related to surgical intervention,but GCS on admission has a significant

关键词： Acute and chronic brain abscess brain abscess outcome surgical management

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Autophagy in neuroinflammation after traumatic brain injury

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Neural Regeneration Research 2024年第5期19卷 951-952页

作者： Chinmoy sarkar Marta M.Lipinski Shock Trauma and Anesthesiology Research(STAR)CenterDepartment of AnesthesiologyUniversity of Maryland School of MedicineBaltimoreMDUSA Department of Anatomy and Neurobiology University of Maryland School of MedicineBaltimoreMDUSA

Traumatic brain injury(TBI)is an acquired injury of the brain caused by the impact of external forces on the brain(Maas et al.,2008).It is a major cause of death and disability among people of all ages(Maas et al.,2008).The primary mechanical injury to the brain initiates a cascade of secondary biochemical events that lead to acute and chronic neurodegeneration and activation of inflammatory pathways(Maas et al.,2008).Both brain-resident microglia and blood-derived myeloid cells-macrophages and monocytes that infiltrate the brain due to injury-induced blood-brain barrier damage,contribute to the inflammatory responses after TBI(Morganti et al.,2015).

关键词： damage death after

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Asian Pacific Journal of Tropical Biomedicine 2024年第8期14卷 319-330页

作者： Priya Bhardwaj Swarnabha sarkar Ritu Mishra Department of Pharmacology All India Institute of Medical SciencesNew Delhi-110029India Department of Physiology All India Institute of Medical SciencesNew Delhi-110029India Department of Zoology University of AllahabadPrayagrajUttar Pradesh-211002India

The recently re-emerged mpox(monkeypox)virus that causes mpox disease is a member of genus Orthopoxvirus and has unprecedentedly spread *** studies have contributed to our understanding of its evolution,pathophysiology,and clinical *** current outbreak of the mpox virus depicts its novel route of transmission as a new ***,the exact reason for its transition from an epidemic to a pandemic remains ***,other poxviruses such as vaccinia virus,variola virus,and cowpox virus,also belong to the same genus,*** the present review,our objective was to summarize the evidence on evolution,pathophysiology,and clinical manifestations of mpox virus and its related *** present review would aid in a better understanding of the current circulating mpox virus and its differences from other *** addition,the shared genetic factors contributing to virulence in these Orthopoxvirus highlight their evolutionary connections and genetic *** they exhibit differences in virulence,studying these genetic relationships is crucial for understanding their biology,pathogenicity,and the development of effective vaccines and antiviral therapeutics to curb mpox disease.

关键词： Evolution Mpox Orthopoxviruses Pathophysiology Poxviruses Transmission

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Application of Optical Hydrogels in Environmental Sensing

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Energy & Environmental Materials 2024年第3期7卷 311-336页

作者： Shuo Yang Shruti sarkar Xing Xie Dan Li Jianmin Chen Shanghai Key Laboratory of Atmospheric Particle Pollution and Prevention(LAP3) Department of Environmental Science and EngineeringFudan UniversityShanghai 200438China School of Civil and Environmental Engineering Georgia Institute of TechnologyAtlanta Georgia 30332USA

The ever-increasing complexity of environmental pollutants urgently warrants the development of new detection *** based on the optical properties of hydrogels enabling fast and easy in situ detection are attracting increasing *** this paper,the data from 138 papers about different optical hydrogels(OHs)are extracted for statistical *** detection performance and potential of various types of OHs in different environmental pollutant detection scenarios were evaluated and compared to those obtained using the standard detection *** on this analysis,the target recognition and sensing mechanisms of two main types of OHs are reviewed and discussed:photonic crystal hydrogels(PCHs)and fluorescent hydrogels(FHs).For PCHs,the environmental stimulus response,target receptors,inverse opal structures,and molecular imprinting techniques related to PCHs are reviewed and ***,the different types of fluorophores(i.e.,compound probes,biomacromolecules,quantum dots,and luminescent microbes)of FHs are ***,the potential academic research directions to address the challenges of applying and developing OHs in environmental sensing are proposed,including the fusion of various OHs,introduction of the latest technologies in various fields to the construction of OHs,and development of multifunctional sensor arrays.

关键词： environmental sensors fluorescent hydrogel optical hydrogel photonic crystal hydrogel pollution detection

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Two-dimensional magnetic materials for spintronic applications

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Nano Research 2024年第2期17卷 743-762页

作者： Shivam N.Kajale Jad Hanna Kyuho Jang Deblina sarkar MIT Media Lab Massachusetts Institute of TechnologyCambridgeMA 02139USA Department of Information Technology and Electrical Engineering ETH ZürichZürich8092Switzerland

Spintronic devices are driving new paradigms of bio-inspired,energy efficient computation like neuromorphic stochastic computing and in-memory *** have also emerged as key candidates for non-volatile memories for embedded systems as well as alternatives to persistent *** meet the growing demands from such diverse applications,there is need for innovation in materials and device designs which can be scaled and adapted according to the ***-dimensional(2D)magnetic materials address challenges facing bulk magnet systems by offering scalability while maintaining device integrity and allowing efficient control of *** this review,we highlight the progress made in experimental studies on 2D magnetic materials towards their integration into spintronic *** provide an account of the various relevant material discoveries,demonstrations of current and voltage-based control of magnetism and reported device systems,while also discussing the challenges and opportunities towards integration of 2D magnetic materials in commercial spintronic devices.

关键词： spintronics van der Waals magnetic tunnel junction(MTJ) spin-orbit torque magnetism

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Early Paleozoic basement diorite of arc-magmatism from Kutch basin, Western India

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Acta Geochimica 2024年第2期43卷 296-307页

作者： Piyush Gupta Sandeep Singh Shakti Singh Rathore Argha Narayan sarkar Geochronology Laboratory KDMIPEOil and Natural Gas Corporation Ltd.9Kaulagarh RoadDehradun 248195India Department of Earth Sciences Indian Institute of TechnologyRoorkee 247667India

In this study,we report for theﬁrst time an Early Palaeozoic basement diorite from the drilled well Nirona-A in the Banni Half-Graben of the Kutch basin,western *** 40Ar–39Ar dates provided a plateau age of 441.84±2.66 Ma and another pseudo plateau of 441.28±5.82 to 388.08±16.65 Ma for the basement *** ages constrain the basement formation age to the Late Ordovician-Early Silurian *** obtained basement ages are correlatable with the later part of Cambro-Ordovician alkaline magmatism that has been reported from the Huqf area in Central Oman,whereas their lithological and petrographic correlativity with base-ment diorites occurring in the Dinsi Body of Nagar Parkar igneous complex in Pakistan can also be *** geochemical studies characterized the diorite with enrich-ment of LILE(Rb,Ba,and K)and LREE(La,Ce,Nd),strong depletion of HFSE(Nb,Sr,P,and Ti),along with weakly negative Eu *** geochemical signatures indicate their petrogenetic afﬁliation with mantle-derived magmas,as well as their tectonic setting to be arc-related,having post-collisional continental-arc type afﬁ****440 Ma basement of Kutch,therefore,appears to rep-resent the later thermal event associated with the reworked Neoproterozoic subduction-related suite from Greater India’s northwest edge,which has implications for Gond-wana assembly in the northwest Indian subcontinent.

关键词： Kutch basin 40Ar–39Ar ages Early palaeozoic basement Continental-arc magmatism Calc-alkaline magmatism

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Dynamics of a delay-induced prey-predator system with interaction between immature prey and predators

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International Journal of Biomathematics 2024年第2期17卷 139-176页

作者： Soumik Pandey Abhijit sarkar Debashis Das Sarbani Chakraborty Department of Mathematics West Bengal State University Barasat-7000126West BengalIndia Department of Basic Science&Humanities JIS College of Engineering Kalyani-741235West BengalIndia

In biological pest control systems,several pests(including insects,mites,weeds,etc.)are controlled by biocontrol agents that rely primarily on *** this biocontrol management ecology,we have created a three-tier prey-predator model with prey phase structure and predator gestation *** studies have demonstrated that predators with Holling type-II functional responses sometimes consume immature prey.A study of the well-posedness and local bifurcation(such as saddle-node and transcritical)near the trivial and planer equilibrium points is carried *** any time lag,the prey development coeficient has a stabilizing impact,while increasing attack rate accelerates *** transformation rate and handling time are shown to cause multiple stability switches in the *** results demonstrate time delay is the key destabilizer that destroys *** model can replicate more realistic events by including time-dependent factors and exploring the dynamic behavior of nonautonomous *** the presence of time delay,sufficient conditions of permanence and global attractivity of the nonautonomous system are ***,MATLAB simulations are performed to validate the analytical findings.

关键词： Holling type-II functional response stage-structure bifurcation time delay seasonality

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Dupuytren’s disease:A review

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Chinese Journal of Plastic and Reconstructive Surgery 2024年第3期6卷 142-148页

作者： Malay sarkar Nitin Kashyap Irappa Madabhavi Department of Pulmonary Medicine Indira Gandhi Medical CollegeShimla 171001Himachal PradeshIndia Department of Plastic and Reconstructive Surgery Atal Institute of Medical SuperspecialitiesShimla 171001Himachal PradeshIndia Department of Medical and Pediatric Oncology and Hematology Jawaharlal Nehru Medical CollegeKLE Academy of Higher Education and ResearchBelagaviKarnataka 590010India

Dupuytren’s disease is a well-known benign fibroproliferative disorder that affects the palmar and digital fasciae of the *** spectrum includes nodule formation,cord formation,and flexion contracture of the digits,which may result in functional *** deformities are often progressive and *** is a cornerstone *** review discusses the epidemiology,pathophysiology,risk factors,clinical manifestations,and management of Dupuytren’s disease.

关键词： Dupuytren’s contracture Dupuytren’s disease Palmar aponeurosis Fasciectomy

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An LSTM-based approach to detect transition to lean blowout in swirl-stabilized dump combustion systems

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Energy and AI 2024年第2期16卷 32-41页

作者： Tryambak Gangopadhyay Somnath De Qisai Liu Achintya Mukhopadhyay Swarnendu Sen Soumik sarkar Amazon Web Services AmazonSanta ClaraCAUSA Department of Aerospace Engineering Indian Institute of Technology MadrasChennaiIndia Department of Mechanical Engineering Iowa State UniversityAmesIAUSA Department of Mechanical Engineering Jadavpur UniversityKolkataIndia

Lean combustion is environment friendly with low NO_(x)emissions providing better fuel efficiency in a combustion ***,approaching towards lean combustion can make engines more susceptible to an undesirable phenomenon called lean blowout(LBO)that can cause flame extinction leading to sudden loss of *** the design stage,it is quite challenging for the scientists to accurately determine the optimal operating limits to avoid sudden LBO ***,it is crucial to develop accurate and computationally tractable frameworks for online LBO prediction in low NO_(x)emission *** the best of our knowledge,for the first time,we propose a deep learning approach to detect the transition to LBO in combustion *** this work,we utilize a laboratory-scale swirl-stabilized combustor to collect acoustic data for different *** each protocol,starting far from LBO,we gradually move towards the LBO regime,capturing a quasi-static time series dataset at different *** one of the protocols in our dataset as the reference protocol,we find a transition state metric for our trained deep learning model to detect the imminent LBO in other test *** find that our proposed approach is more precise and computationally faster than other baseline models to detect the transition to ***,we endorse this technique for monitoring the operation of lean combustion engines in real time.

关键词： Deep learning LSTM Detection of lean blowout Transition to LBO Confusion matrix

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Tale of mitochondria and mitochondria-associated ER membrane in patient-derived neuronal models of Wolfram syndrome

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Neural Regeneration Research 2025年第9期20卷 2587-2588页

作者： Laetitia Aubry Timothy Barrett Sovan sarkar I-STEM CECSCorbeil-EssonnesFrance UniversitéParis-Saclay Universitéd’EvryINSERMI-STEMUMR861Corbeil-EssonnesFrance Institute of Cancer and Genomic Sciences Institute of Biomedical ResearchCollege of Medical and Dental SciencesUniversity of BirminghamEdgbastonBirminghamUK Department of Endocrinology Birmingham Women’s and Children’s HospitalSteelhouse LaneBirminghamUK

Mitochondria and mitochondria-associated endoplasmic reticulum membrane in neurodegenerative diseases:Mitochondria generate most of the chemical energy needed to power the biochemical reactions of cells,and thus are often referred to as the"powerhouse"of the ***,this organelle is also involved in a pleth,ora of different cellular functions such as calcium(Ca^(2+))homeostasis,apoptosis,oxidative stress,and several metabolic pathways including oxidative phosphorylation,tricarboxylic acid cycle,andβ-oxidation of fatty acids.

关键词： oxidative cycle carboxylic

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