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Modeling frequency distributions of tree height, diameter and crown area by six probability functions for open forests of Quercus persica in Iran

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Journal of Forestry Research 2016年第4期27卷 901-906页

作者： Mehrdad Mirzaei Jalal Aziz Ali mahdavi Asma Mohammad Rad University of Guilan Sowmeh Sara City GuilanIslamic Republic of Iran Faculty of Natural Resources University of GuilanSowmeh Sara Islamic Republic of Iran Faculty of Agriculture university of Ilam IlamIslamic Republic of Iran Faculty of Natural Resources University of Tehran KarajIslamic Republic of Iran

The prediction of the distribution of quantitative variables in a forest stand is of great interest to forest managers, for the evaluation of forest resources and scheduling of future silvicultural treatments. The aim of this research was to model the distribution of quantitative variables for Quercus persica in open forests in Iran. To investigate the probability distribution of trees in natural stands, 642 trees were selected for measurement using a systematic random sampling method. Selected trees were measured and data were analyzed. Gamma, beta, normal,lognormal, exponential and Weibull probability distributions were fitted to the height distribution of trees. Variables of distribution functions were estimated using the maximum likelihood estimation method. Actual probability and probability which derived from functions was compared using Kolmogorov–Smirnov and Anderson–Darling tests. Beta, Weibull and Weibull probability distributions explained the distributions of tree height, DBH and crown area.

关键词： forests Quercus stands crown canopy Weibull Kolmogorov Darling exponential fitted

Guanosine 5'-triphosphate induces differentiation-dependent apoptosis in human leukemia U937 and KG1 cells

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Acta Pharmacologica Sinica 2006年第9期27卷 1175-1184页

作者： Razieh YAZDANPARAST Mohammad Amin MOOSAVI Majid mahdavi Abbas LOTFI Institute of Biochemistry and Biophysics P O Box 13145-1384 University of TehranTehranIran National Research Center for Genetic Engineering and BiotechnologyP O Box 14155-6343 TehranIran

Aim:The differentiation capability of guanosine 5′-triphosphate（GTP）was stud-ied using U937 and KG1 ***:Cell cycle was analyzed by PI stainingusing flow *** was measured by Annexin-V-FITC/PI doublestaining using flow *** was observed by morphologicalcriteria,Wright-Giemsa staining and expression of cell surface markers CD 11b ***:Variable GTP concentrations（25-200 μmol/L）at short treatmenttimes（up to 24 h）showed significant anti-proliferative activities among both ***,longer treatment times（up to 72 h）were required to ***-cycle analyses of the GTP-treated cells indicated an increase in S-phase population by 48 h followed by the appearance of a sub-G1peak after 72hof *** effects of GTP on U937 and KG1 cells were accompanied withdifferentiation toward monocyte/macrophage *** was evidenced by asharp increase in the extent of CD 11b and CD 14 expression after 24 h of exposureto *** viability of both cell types did not significantly change during thefirst 24 ***,at longer treatment times（72-96 h）,dramatic decreases inboth the extent of CD14 expression and the cell viabilities were ***-taneous measurement of apoptosis and CD 14 expression in GTP-treated U937cells indicated that cells with lower CD14 content underwent more ***:These finding may pave the way for further pharmaceutical evalua-tion of GTP as a suitable differentiating agent for acute myeloblastic leukemia（AML）therapy.

关键词： apoptosis cell-cycle arrest guanosine 5’-triphosphate differentiation KG1 U937

Effects of Hydro-alcoholic Extract of Launaea acanthodes on Serum Gonadotropin and Testosterone Levels and the Structure of Seminiferous Tubules in Hyperglycemic Rats

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Chinese Journal of Integrative Medicine 2016年第3期22卷 207-213页

作者： Ameneh Mohammadi Morteza Behnam-Rassouli Zeinab Momeni Naser mahdavi-Shahri Department of Biology Faculty of ScienceFredowsi University of Mashhad

Objective： To investigate the effects of hydro-alcoholic extract of Launaea acanthodes, a blood glucose lowering plant in folk medicine of Iran, on the structure of seminiferous tubules and serum gonadotropin and testosterone levels in hyperglycemic rats. Methods： Twenty-four Wistar rats were randomly allocated into 4 groups （n=6）： control, streptozotocin （STZ）, STZ ＋ insulin [STZ ＋ Ins, 5 IU/（kg·day）], and STZ ＋ Launaea acanthodes extract [STZ ＋ Ext, 150 mg/（kg·day）]. Blood samples were collected at the 2nd and 4th weeks for detection of testosterone, follicle stimulating hormone （FSH） and luteinizing hormone （LH） with enzyme-linked immuno sorbent assay （ELISA）, and the dght testes of rats were removed at the 7th week for the evaluation of diameter and wall thickness of seminiferous tubules and number of Leydig cells using unbiased stereological techniques. Results： in comparison with the control group, at the 2nd week FSH （0.45 vs 0.03, 0.02, 0.02 lUlL in STZ, STZ ＋ Ins and STZ ＋ Ext groups, respectively） and LH （1.02 vs 0.37, 0.2, 0.29 IU/L） showed significant decreases （all P〈0.05） and testosterone （4.2 vs 8.37, 7.78, 11.8 ng/mL） showed a remarkable increase （all P〈0.05）. The levels of these hormones became closer in the STZ ＋ Ext and the STZ ＋ Ins groups to the control at the 4th week. A significant decrease in diameter and wall thickness of seminiferous tubules and number of Leydig cells were observed in the STZ group as compared with the control （P〈0.01）. Conclusions： Administration of Launaea extract demonstrated a beneficial impact on the protection of testis from pathogenic and degenerative effects of hyperglycemia which may be partly due to its potential antioxidative effects.

关键词： hyperglycemia Launaea acanthodes testis gonadotropins testosterone rat

Prediction of Protein-Protein Interactions Using Protein Signature Profiling

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Genomics, Proteomics & Bioinformatics 2007年第3期5卷 177-186页

作者： Mahmood A.mahdavi Yen-Han Lin Department of Chemical Engineering University of SaskatchewanSaskatoonSK S7N 5A9Canada.

Protein domains are conserved and functionally independent structures that play an important role in interactions among related proteins. Domain-domain interactions have been recently used to predict protein-protein interactions （PPI）. In general, the interaction probability of a pair of domains is scored using a trained scoring function. Satisfying a threshold, the protein pairs carrying those domains are regarded as ＂interacting＂. In this study, the signature contents of proteins were utilized to predict PPI pairs in Saccharomyces cerevisiae, Caenorhabditis elegans, and Homo sapiens. Similarity between protein signature patterns was scored and PPI predictions were drawn based on the binary similarity scoring function. Results show that the true positive rate of prediction by the proposed approach is approximately 32% higher than that using the maximum likelihood estimation method when compared with a test set, resulting in 22% increase in the area under the receiver operating characteristic （ROC） curve. When proteins containing one or two signatures were removed, the sensitivity of the predicted PPI pairs increased significantly. The predicted PPI pairs are on average 11 times more likely to interact than the random selection at a confidence level of 0.95, and on average 4 times better than those predicted by either phylogenetic profiling or gene expression profiling.

关键词： protein-protein interaction protein signature ROC curve

Validation of nutritional risk index method against patientgenerated subjective global assessment in screening malnutrition in colorectal cancer patients

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Chinese Journal of Cancer Research 2013年第5期25卷 544-548页

作者： Elnaz Faramarzi Reza mahdavi Mohammad Mohammad-Zadeh Behnam Nasirimotlagh Student research committee Tabriz University of Medical Sciences Nutrition Research Center Tabriz University of Medical Sciences Department of Radiotherapy Imam Khomeini HospitalTabriz University of Medical Sciences

Objective：To validate malnutrition screening tool of nutrition risk index （NRI） against patent-generated subjective global assessment （PG-SGA） as a gold standard tool in colorectal cancer patients before ***：Nutritional status of 52 volunteer colorectal cancer patients with a mean age of 54.1±16.8 years who referred to radiotherapy center were assessed by PG-SGA （gold standard method） and *** albumin levels of patients were determined by colorimetric method.A contingency table was used to determine the sensitivity,specificity,and predictive value of the NRI in screening patients at risk of malnutrition,in comparison with the PG-SGA in patients before ***：The findings of PG-SGA and NRI showed that 52％ and 45％ of patients in our study were moderately or severely malnourished *** NRI had a sensitivity of 66％ and a specificity of 60％ against *** positive predictive value was 64％ and the negative predicative value was 62％.The agreement between NRI and PG-SGA was statistically insignificant （kappa =0.267; P＞0.05）.Conclusions：The findings of present study showed that the prevalence of malnutrition was high in patients with colorectal ***,NRI method had low sensitivity and specificity in assessing nutritional status of patients with *** seems that the combination of anthropometric,laboratory parameters and a subjective scoring system may be helpful tools in screening of malnutrition in cancer patients.

关键词： Colorectal cancer patients malnutrition patient-generated subjective global assessment nutrition risk index (NRI)

Speckle filtering of Synthetic Aperture Radar images using filters with object-size-adapted windows

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International Journal of Digital Earth 2018年第7期11卷 703-729页

作者： Sahel mahdavi Bahram Salehi Cecilia Moloney Weimin Huang Brian Brisco C-CORE Faculty of Engineering and Applied ScienceMemorial University of NewfoundlandSt John’sNLCanada Department of Electrical Engineering Faculty of Engineering and Applied ScienceMemorial University of NewfoundlandSt.John’sNLCanada Canada Center for Mapping and Earth Observation OttawaONCanada

Speckle degrades the radiometric quality of a Synthetic Aperture Radar(SAR)*** methods for speckle reduction have used a fixedsize window for filtering the entire ***,however,may not be effective for the entire image,as land covers of different sizes require different filtering *** this paper,a novel method is proposed by which each pixel in the image is filtered with a window appropriate for the size of object within *** real in-phase and the imaginary quadrature components of the SAR images determine the best window size and the pixels in the intensity image are filtered using their own optimal *** proposed method is presented for both singleand multi-polarized SAR images,and the results of several common filters that were modified are *** approach is applied to two RADARSAT-2 images:one over San Francisco,California,USA and the other over ***’s,Newfoundland and Labrador,Canada,producing results that were similar to,or outperformed,comparable filters while retaining details and suppressing speckle *** the method was successful for single-look intensity data,it offers great potential for multi-look and amplitude data as well.

关键词： Speckle Synthetic Aperture Radar(SAR) filters adaptive window size

Down-regulation of Halr1 during induced differentiation of embryonal carcinoma P19 cells

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BIOCELL 2019年第3期43卷 145-154页

作者： ZAHRA HOSSEININIA SARA SOLTANIAN NASER mahdavi-SHAHRI HESAM DEHGHANI Division of Biotechnology Faculty of Veterinary MedicineFerdowsi University of MashhadMashhadIran Department of Biology Faculty of SciencesShahid Bahonar University of KermanKermanIran Department of Biology Faculty of SciencesFerdowsi University of MashhadMashhadIran Stem Cells and Regenerative Medicine Research Group Research Institute of BiotechnologyFerdowsi University of MashhadMashhadIran

Maintenance of pluripotency depends to diverse regulatory *** in embryonic stem cells(ESCs)have indicated that large intergenic non-coding RNAs(lincRNAs)are involved in the regulatory network of ***,the presence and function of pluripotency-associated lincRNAs in cancer cells with pluripotency features are *** this study,we used embryonal carcinoma(EC)P19 cell lines to investigate the expression level of Halr1 in pluripotency and retinoic acid(RA)-induced differentiated ***-regulation of pluripotency associated factors such as OCT4,NANOG,SSEA1 and alkaline phosphatase at transcript and protein levels were used to confirm the differentiated status of P19 *** measurement of Halr1 transcript levels revealed a 79% decrease during RA-induced differentiation of P19 *** results indicate that upon exiting the pluripotency state the expression level of Halr1 similar to core pluripotency factors is remarkably reduced.

关键词： Differentiation Halr1 lincRNA Pluripotency P19 cell Retinoic acid

Effects of Royal Jelly Supplementation on Glycemic Control and Oxidative Stress Factors in Type 2 Diabetic Female:A Randomized Clinical Trial

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Chinese Journal of Integrative Medicine 2014年第5期20卷 347-352页

作者： Samira Pourmoradian Reza mahdavi Majid Mobasseri Elnaz Faramarzi Mehrnoosh Mobasseri Nutrition Research Center Tabriz University of Medical SciencesTabrizIran Endocrinology Department of Medicine Faculty Tabriz University of Medical SciencesTabrizIran Student Research Committee Faculty of NutritionTabriz University of Medical SciencesTabrizIran Faculty of Medicine Tabriz University of Medical SciencesTabrizIran

Objective： It has been proposed that royal jelly has antioxidant properties and may improve oxidative stress and glycemic control. Therefore, we investigated the effects of royal jelly supplementation in diabetic females. Methods： In this pilot, parallel design randomized clinical trial, 50 female volunteers with type 2 diabetes were randomly allocated to the supplemented （25, cases） and placebo （25, cases） groups, based on random block procedure produced by Random Allocation Software, given a daily dose of 1,000 mg royal jelly soft gel or placebo, respectively, for 8 weeks. Before and after intervention, glycemic control indices, antioxidant and oxidative stress factors were measured. Results： After royal jelly supplementation, the mean fasting blood glucose decreased remarkably （163.05_± 42.51 mg/dL vs. 149.68 ± 42.7 mg/dL）. Royal jelly supplementation resulted in significant reduction in the mean serum glycosylated hemoglobin levels （8.67%± 2.24% vs. 7.05% ± 1.45%, P=0.001） and significant elevation in the mean insulin concentration （70.28 ± 29.16 pmol/L vs. 86.46± 27.50 pmol/L, P=0.01）. Supplementation significantly increased erythrocyte superoxidase dismutase and glutathione peroxidase activities and decreased malondialdehyde levels （P〈0.05）. At the end of study, the mean total antioxidant capacity elevated insignificantly in both groups. Conclusions： On the basis of our findings, it seems that royal jelly supplementation may be beneficial in controlling diabetes outcomes. Further studies with larger sample size are warranted.

关键词： glycemic control oxidative stress Royal jelly type 2 diabetes

Existence of Nonabelian Free Subgroups in the Maximal Subgroups of GLn（D）

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Algebra Colloquium 2014年第3期21卷 483-496页

作者： H.R. Dorbidi R. Fallah-Moghaddam M. mahdavi-Hezavehi Department of Mathematical Sciences Sharif University of 3bchnology P.O. Box 11155-3415 Tehran Iran

Given a non-commutative finite dimensional F-central division algebra D, we study conditions under which every non-abelian maximal subgroup M of CLn （D） contains a non-cyclic free subgroup. In general, it is shown that either M contains a non-cyclic free subgroup or there exists a unique maximal subfield K of Mn（D） such that NCLn（D）（K＊） = M, K＊ △ M, K/F is Galois with Gal（K/F） ≌ M/K＊, and F[M] = in（D）. In particular, when F is global or local, it is proved that if （[D ： F], Char（F）） = 1, then every non- abelian maximal subgroup of GL1 （D） contains a non-cyclic free subgroup. Furthermore, it is also shown that GLn（F） contains no solvable maximal subgroups provided that F is local or global and n ≥ 5.

关键词： free subgroup maximal subgroup central simple algebralotion