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The Case Report on the Effectiveness of Infrared Light on Acid Burn Victim

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Case Reports in Clinical Medicine 2022年第12期11卷 527-533页

作者： maha Farhina Plastic Surgery Department Dr. Ruth K. M. Pau Civil Hospital Karachi Pakistan

Burn injuries are common in Pakistan. However, most people are reluctant to have infrared treatment for their wounds. This study investigated the efficacy of infrared treatment on burn wounds. The procedure involved a burn victim who had sustained acid burns to the neck and face. Nectrotomy was done to remove dead tissue from the burn wound, and after treatment, Low-Level Light was used to reduce pain and enhance healing in the patient. Initial results showed mild hypertrophic scars, no stiffness. Post-operation therapy included physical training regimens and massage. The patient showed satisfactory results and felt less tightness in neck movements by the following treatment. The article concludes by showing that infrared light promoted repair and regrowth at a cellular level.

关键词： Infrared Therapy Acid Burns Photobiomodulation Low Light Laser Therapy Red Light

Berrettini Anastomosis Iatrogenic Injury Relating to Carpel Tunnel Syndrome Case Study

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International Journal of Clinical Medicine 2022年第11期13卷 494-500页

作者： maha Farhina Plastic Surgery Department Dr. Ruth K.M Pfau Civil Hospital Karachi Karachi Pakistan

Some diseases require medical mitigation following the diagnosis, and sometimes the situation means that the patient has to undertake strong medication. However, this medicine is designed pharmacodynamically to interact with other organs before they reach the intended organ. Some mitigation imposes challenges on the involved organ. While the main organ will be healed, some drugs’ footprints will be left out to other organs. These are called iatrogenic injuries. In the case of anastomosis, it requires the alteration of surgical methods or the origin of iatrogenic injury in the arm;thus, the knowledge of anastomosis is very important to the field of medical practice. In addition, carpal tunnel release becomes vital in curing carpal tunnel syndrome. The paper focuses on a case of a 42-year-old woman found to have a complication to her middle finger. This case becomes important for studying Berrettini anastomosis iatrogenic injury, which relates to carpal tunnel syndrome. The Berrettini branch is a complication that facilitates communication between the superficial ulnar and median nerve. The analysis also provides the electro-diagnostic evidence of Berrettini anastomosis on how it can give a position three-finger and thus contribute to a force explanation of the median neuropraxia. Lastly, the paper provides information on the implication of the Berrettini branch for surgical use. The implication of pictures in the digital era can be used to analyze the varied connection and length between the median nerve and ulnar section. It’s easy to locate the position of high risk of iatrogenic injury in the palm due to the consistent location of Berrettini communication branches. The precaution is that operations have to be conducted moderately for a clear vision as the carefully mitigated practice ensures protection from the destruction and injury of the surrounding structures.

关键词： Iatrogenic Injury Berrettini Anastomosis (BA) SNAP-Sensory Nerve Action Potential CTS-Carpal Tunnel Syndrome Median Nerve Ulnar Nerve

Suppression of NLRP3 inflammasome by ivermectin ameliorates bleomycin-induced pulmonary fibrosis

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Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2023年第8期24卷 723-733页

作者： Mai A.ABD-ELMAWLA Heba R.GHAIAD Enas S.GAD Kawkab A.AHMED maha ABDELMONEM Department of Biochemistry Faculty of PharmacyCairo UniversityCairo 11562Egypt Department of Pharmaceutical Sciences Faculty of PharmacyKing Faisal UniversityAl-Ahsa 31982Saudi Arabia Department of Pharmacology and Toxicology Faculty of PharmacySinai UniversityIsmailia 45511Egypt Department of Pathology Faculty of Veterinary MedicineCairo UniversityCairo 12211Egypt

Ivermectin is a US Food and Drug Administration(FDA)-approved antiparasitic agent with antiviral and anti-inflammatory *** recent studies reported the possible anti-inflammatory activity of ivermectin in respiratory injuries,its potential therapeutic effect on pulmonary fibrosis(PF)has not been *** study aimed to explore the ability of ivermectin(0.6 mg/kg)to alleviate bleomycin-induced biochemical derangements and histological changes in an experimental PF rat *** can provide the means to validate the clinical utility of ivermectin as a treatment option for idiopathic *** results showed that ivermectin mitigated the bleomycin-evoked pulmonary injury,as manifested by the reduced infiltration of inflammatory cells,as well as decreased the inflammation and fibrosis ***,ivermectin decreased collagen fiber deposition and suppressed transforming growth factor-β1(TGF-β1)and fibronectin protein expression,highlighting its anti-fibrotic *** study revealed for the first time that ivermectin can suppress the nucleotide-binding oligomerization domain(NOD)-like receptor family pyrin domain-containing protein 3(NLRP3)inflammasome,as manifested by the reduced gene expression of NLRP3 and the apoptosis-associated speck-like protein containing a caspase recruitment domain(ASC),with a subsequent decline in the interleukin-1β(IL-1β)*** addition,ivermectin inhibited the expression of intracellular nuclear factor-κB(NF-κB)and hypoxia‑inducible factor‑1α(HIF-1α)proteins along with lowering the oxidative stress and apoptotic ***,this study revealed that ivermectin could ameliorate pulmonary inflammation and fibrosis induced by *** beneficial effects were mediated,at least partly,via the downregulation of TGF-β1 and fibronectin,as well as the suppression of NLRP3 inflammasome through modulating the expression of HIF‑1αand NF-κB.

关键词： Intra-tracheal instillation Immunohistochemistry Transforming growth factor-β1(TGF-β1) Nuclear factor-κB(NF-κB) Lung fibrosis

Frequency of Musculoskeletal Pain among Surgeons in Karachi

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Case Reports in Clinical Medicine 2022年第8期11卷 297-305页

作者： maha Farhina Plastic Surgery Department Dr. Ruth K.M Pfau Civil Hospital Karachi Karachi Pakistan

To determine the dynamic physical strain exerted on an individual during work, an evaluation of all physical performances is necessary. For surgeons, sustaining healthy ergonomics is essential, particularly for cases requiring long standing hours. Indeed, the absence of proper ergonomics may lead to multiple musculoskeletal issues. Failure to check these problems may lead to future degenerative changes and eventually career-ending damages. Pain among surgeons is expected since they spend many hours caring for patients that they ignore their health, standing for prolonged hours. Lack of attention to work ergonomics often leads to work-related muscle pain and increased risk of problems.

关键词： Musculoskeletal Pain Ergonomics Orthopedic Surgeons Karachi

Motor Response of Mirror Therapy after Reconstruction of Extensor Mechanism Caused by Glass Cut Injury

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Case Reports in Clinical Medicine 2022年第8期11卷 273-279页

作者： maha Farhina Plastic Surgery Department Dr. Ruth K. M Pfau Civil Hospital Karachi Karachi Pakistan

Treatment by mirror therapy (MT) restores motion in injured limbs without invasive procedures. This process is widely accepted for rehabilitating patients with phantom limb pain, stroke victims, or patients who need therapy after nerve damage. The procedure is specifically useful in restoring motion to the hand after surgical repairs to the extensor muscle and tendons. Mirror therapy rewires the brain by making the restored limb remember hand motions by observing the motions of a normal hand. The concept of a mirror image is that the movement of the uninjured arm forms the illusion of the same movement in the affected arm. Efforts to repeat hand movements elicit the same reaction in the affected hand in what is referred to as Hebbian learning. This case study evaluated MT’s effectiveness in motion restoration after a glass injury. This case study showed restoration of normal hand motions in a patient following surgery to repair a glass cut to the arm. Surgery repaired the lacerated extensor tendon and radial nerve. The muscle belly was repaired, and a graft fixed the nerve gap. Once the arm healed, the patient underwent rehabilitation in mirror therapy to restore normal function in his hand. After conducting mirror therapy, the pain was eliminated, and the patient restored normal function of moving the hand and finger extension. In addition, the therapy could be conducted at home without needing a professional. The effectiveness of mirror therapy was seen in the functional restoration of hand and finger movement. The process is also less complicated as it can be performed at home.

关键词： Mirror Therapy Glass Cut Injury Neuro-Musculoskeletal Extensor Tendon Injury Extensor Muscles

Mathematical Modelling of Quantum Kernel Method for Biomedical Data Analysis

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Computers, Materials & Continua 2022年第6期71卷 5441-5457页

作者： Mahmoud Ragab Ehab Bahauden Ashary maha Farouk S.Sabir Adel A.Bahaddad Romany F.Mansour Information Technology Department Faculty of Computing and Information TechnologyKing Abdulaziz UniversityJeddah21589Saudi Arabia Centre of Artificial Intelligence for Precision Medicines King Abdulaziz UniversityJeddah21589Saudi Arabia Mathematics Department Faculty of ScienceAl-Azhar UniversityNaser City11884CairoEgypt Electrical and Computer Engineering Department Faculty of EngineeringKing Abdulaziz UniversityJeddah21589Saudi Arabia Information Systems Department Faculty of Computing and Information TechnologyKing Abdulaziz UniversityJeddah21589Saudi Arabia Mathematics Department Faculty of ScienceNew Valley UniversityEl-Kharga72511Egypt

This study presents a novelmethod to detect themedical application based on Quantum Computing(QC)and a few Machine Learning(ML)*** has a primary advantage i.e.,it uses the impact of quantum parallelism to provide the consequences of prime factorization issue in a matter of ***,this model is suggested for medical application only by recent researchers.A novel strategy i.e.,Quantum KernelMethod(QKM)is proposed in this paper for data *** this QKM process,Linear Tunicate Swarm Algorithm(LTSA),the optimization technique is used to calculate the loss function initially and is aimed at medical *** output of optimization is either 0 or 1 i.e.,odd or even in *** this output value,the data is identified according to the ***,the method also reduces time,saves cost and improves the efficiency by feature selection process i.e.,Filter *** the features are extracted,QKM is deployed as a classification model,while the loss function is minimized by *** motivation of the minimal objective is to remain ***,some computations can be performed more efficiently by the proposed *** testing,the test data was evaluated by minimal loss *** outcomes were assessed in terms of accuracy,computational time,and so *** this,databases like Lymphography,Dermatology,and Arrhythmia were used.

关键词： Medical data classification feature selection qkm classifier ltsa optimization

Inter-Calibration Between Plasma Instruments Onboard DEMETER

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Plasma Science and Technology 2008年第5期10卷 539-545页

作者： maha S.QUASSIM National Research Institute of Astronomy and Geophysics Helwan 11421CairoEgypt

The in-situ measurements of the ionospheric plasma that we use come from two instruments of the scientific payload of the satellite DEMETER; the plasma analyser IAP （Instrument d＇analyse du plasma） and the Langmuir probe ISL （Instrument Sonde de Langmuir）. DEMETER is a micro-satellite realized by the CNES（Centre National d＇Etudes Spatiales, France） with a principal objective to seek a possible influence of the seismic activity on the electromagnetic waves in the ionosphere and on the ionospheric plasma. The satellite was placed on June 29, 2004, in a circular and quasi helio-synchronous orbit at -710 km altitude. The experiments function primarily at mid-latitudes （from ＋60° to -60°）. The IAP data were analysed to deduce the ion population （densities of the dominant ions, i.e. generally O^＋, H^＋ and He^＋） therefore the total ion density. The use of data IAP thus requires some precaution to make sure that the electric equilibrium conditions of the satellite, such as the satellite potential （Фsat）, are obtained during the treatment of routine, does not induce an error of measurement. When this potential is negative, the minority light ions H^＋ and He^＋ can be measured in a reliable way when their proportion is above 3% to 5% of that of O^＋. The critical limitation is： under certain conditions, the satellite potential becomes positive and reach a value about -0.5 V so that it becomes impossible to measure H^＋ ions. This is likely to involve a significant error on the composition and the density of the plasma. Therefore we carried out a calibration to estimate the missing density. The ISL experiment （Langmuir probe） provided the collected current/polarized tension characteristics of a cylindrical probe from which both electron density Ne and temperature Te were obtained. In some situations it is necessary to examine the accuracy of the electron density using another technique, for instance the high frequency （HF） spectrogram, provided by ICE （instrument champ electrique

关键词： plasma analyser satellite plasma observation ion density measuring

Optimized Artificial Neural Network Techniques to Improve Cybersecurity of Higher Education Institution

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Computers, Materials & Continua 2022年第8期72卷 3385-3399页

作者： Abdullah Saad AL-Malaise AL-Ghamdi Mahmoud Ragab maha Farouk S.Sabir Ahmed Elhassanein Ashraf A.Gouda Information Systems Department Faculty of Computing and Information Technology King Abdulaziz UniversityJeddah21589Saudi Arabia Information Technology Department Faculty of Computing and Information TechnologyKing Abdulaziz UniversityJeddah21589Saudi Arabia Centre of Artificial Intelligence for Precision Medicines King Abdulaziz UniversityJeddah21589Saudi Arabia Mathematics Department Faculty of ScienceAl-Azhar UniversityNaser City11884CairoEgypt Mathematics Department College of ScienceUniversity of BishaBishaSaudi Arabia Mathematics Department Faculty of ScienceDamanhour UniversityDamanhourEgypt

Education acts as an important part of economic growth and improvement in human *** educational sectors have transformed a lot in recent days,and Information and Communication Technology(ICT)is an effective part of the education *** every action in university and college,right from the process fromcounselling to admissions and fee deposits has been *** records,quiz,evaluation,mark,and grade submissions involved the utilization of the ***,security is essential to accomplish cybersecurity in higher security institutions(HEIs).In this view,this study develops an Automated Outlier Detection for CyberSecurity in Higher Education Institutions(AOD-CSHEI)*** AOD-CSHEI technique intends to determine the presence of intrusions or attacks in the *** AOD-CSHEI technique initially performs data pre-processing in two stages namely data conversion and class *** addition,the Adaptive Synthetic(ADASYN)technique is exploited for the removal of outliers in the ***,the sparrow search algorithm(SSA)with deep neural network(DNN)model is used for the classification of data into the existence or absence of intrusions in the HEIs ***,the SSA is utilized to effectually adjust the hyper parameters of the DNN *** order to showcase the enhanced performance of the AOD-CSHEI technique,a set of simulations take place on three benchmark datasets and the results reported the enhanced efficiency of the AOD-CSHEI technique over its compared methods with higher accuracy of 0.9997.

关键词： Higher security institutions intrusion detection system artificial intelligence deep neural network hyperparameter tuning deep learning

In flue nee of microwave drying and con venti onal drying methods on the mechanical properties of naproxen sodium drug tablets

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Particuology 2020年第6期18卷 30-40页

作者： maha Al-Ali Rajarathinam Parthasarathy Chemical and Environmental Engineering School of EngineeringRM1T UniversityMelbourneVictoria 3001Australia

Tablets are one of the most comm only used solid dosage forms taken by *** preparati on of high-quality tablets requires an understanding of the preparation process and elucidation of how the physical and mechanical properties change as a function of the preparation *** work aims to investigate the impact of microwave irradiation drying and conventional drying methods(including freeze,convective and vacuum drying)on the hardness,tensile strength and friability of tablets made from a multi-component formulation containing naproxen sodium,microcrystalline cellulose,and *** results show that tablets subjected to microwave drying had the secondhighest tensile strength and hardness of 1.296 MPa and 67 N,*** tablets subjected to vacuum drying had the lowest tensile strength and hardness of 1.21 MPa and 64 N,*** friability index values for the tablets derived from the microwave and freeze-drying methods werel%.Microwave drying was observed to be an efficient method to produce naproxen sodium-containing tablets with satisfactory mechanical *** findings confirm that the drying method plays an essential role in the improvement or degradation of the mechanical properties of tablets.

关键词： Microwave drying Naproxen sodium Hardness Friability Tensile strength