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New simple spectrophotometric method for determination of the binary mixtures(atorvastatin calcium and ezetimibe;candesartan cilexetil and hydrochlorothiazide) in tablets

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Journal of Pharmaceutical Analysis 2013年第2期3卷 118-126页

作者： Tarek S.Belal Hoda G.Daabees magdi m.abdel-khalek mohamed S.mahrous mona m.Khamis Pharmaceutical Analytical Chemistry Department Faculty of PharmacyUniversity of AlexandriaElmessalah 21521AlexandriaEgypt Pharmaceutical Chemistry Department Faculty of PharmacyUniversity of AlexandriaElmessalah 21521AlexandriaEgypt

A new simple spectrophotometric method was developed for the determination of binary mixtures without prior *** method is based on the generation of ratio spectra of compound X by using a standard spectrum of compound Y as a *** peak to trough amplitudes between two selected wavelengths in the ratio spectra are proportional to concentration of X without interference from *** method was demonstrated by determination of two drug *** first consists of the two antihyperlipidemics：atorvastatin calcium（ATV） and ezetimibe（EZE）,and the second comprises the antihypertensives：candesartan cilexetil（CAN） and hydrochlorothiazide（HCT）.For mixture 1,ATV was determined using 10 μg/mL EZE as the divisor to generate the ratio spectra,and the peak to trough amplitudes between 231 and 276 nm were plotted against ATV ***,by using 10 μg/mL ATV as divisor,the peak to trough amplitudes between 231 and 276 nm were found proportional to EZE *** curves were linear in the range 2.5-40 mg/mL for both *** mixture 2,divisor concentration was 7.5 μg/mL for both *** was determined using its peak to trough amplitudes at 251 and 277 nm,while HCT was estimated using the amplitudes between 251 and 276 *** measured amplitudes were linearly correlated to concentration in the ranges 2.5-50 and 1-30 μg/mL for CAN and HCT,*** proposed spectrophotometric method was validated and successfully applied for the assay of both drug combinations in several laboratory-prepared mixtures and commercial tablets.

关键词： Spectrophotometric analysis Ratio spectra Atorvastatin Ezetimibe Candesartan Hydrochlorothiazide

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Distributed H2/H∞ Filter Design for Discrete-Time Switched Systems

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IEEE/CAA Journal of Automatica Sinica 2020年第1期7卷 158-168页

作者： Nezar m.Alyazidi magdi S.mahmoud Systems Engineering Department King Fahd University for Petroleum and Minerals

This paper addresses an infinite horizon distributed H2/H∞ filtering for discrete-time systems under conditions of bounded power and white stochastic signals. The filter algorithm is designed by computing a pair of gains namely the estimator and the coupling. Herein, we implement a filter to estimate unknown parameters such that the closed-loop multi-sensor accomplishes the desired performances of the proposed H2 and H∞ schemes over a finite horizon. A switched strategy is implemented to switch between the states once the operation conditions have changed due to disturbances. It is shown that the stability of the overall filtering-error system with H2/H∞ performance can be established if a piecewise-quadratic Lyapunov function is properly constructed. A simulation example is given to show the effectiveness of the proposed approach.

关键词： Bounded power stochastic disturbance discretetime systems H2/H∞ filtering infinite horizon multi-sensor switched systems

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Fundamental Issues in Networked Control Systems

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IEEE/CAA Journal of Automatica Sinica 2018年第5期5卷 902-922页

作者： magdi S.mahmoud a mutaz m.Hamdan the systems engineering department king fahd university of petroleum and minerals

Abstract--This paper provides a survey on modeling and theories of networked control systems （NCS）. In the first part, modeling of the different types of imperfections that affect NCS is discussed. These imperfections are quantization errors, packet dropouts, variable sampling/transmission intervals, vari- able transmission delays, and communication constraints. Then follows in the second part a presentation of several theories that have been applied for controlling networked systems. These theories include： input delay system approach, markovian system approach, switched system approach, stochastic system approach, impulsive system approach, and predictive control approach. In the last part, some advanced issues in NCS including decentral- ized and distributed NCS, cloud control system, and co-design of NCS are reviewed. Index Terms--Decentralized networked control systems （NCS）, distributed networked control systems, network constraints, net- worked control system, quantization, time delays.

关键词： Decentralized networked control systems(NCS) distributed networked control systems network constraints networked control system quantization time delays

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Robust Control Design of Wheeled Inverted Pendulum Assistant Robot

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IEEE/CAA Journal of Automatica Sinica 2017年第4期4卷 628-638页

作者： magdi S.mahmoud mohammad T.Nasir Systems Engineering Department King Fahd University of Petroleum and MineralsDhahran 31261Saudi Arabia

This paper examines the design concept and mobile control strategy of the human assistant robot I-PENTAR(inverted pendulum type assistant robot). The motion equation is derived considering the non-holonomic constraint of the twowheeled mobile robot. Different optimal control approaches are applied to a linearized model of I-PENTAR. These include linear quadratic regulator(LQR), linear quadratic Gaussian control(LQG), H_2 control and H_∞ control. Simulation is performed for all the approaches yielding good performance results.

关键词： I-PENTAR robot linear quadratic regulator(LQR) control design model predictive control(mPC) observerbased feedback control robust H_∞ control

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Networked Control Approach for Distributed Generation Systems

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IEEE/CAA Journal of Automatica Sinica 2018年第4期5卷 836-851页

作者： magdi S.mahmoud mohamed Saif Ur Rahman Systems Engineering Department King Fahd University of Petroleum and MineralsP.O.Box 5067Dhahran 31261Saudi Arabia

microgrid has emerged as an answer to growing demand for distributed generation(DG) in power systems. It contains several DG units including microalternator, photovoltaic system and wind generation. It turns out that sustained operation relies on the stability of these constituent systems. In this paper, a microgrid consisting of microalternator and photovoltaic system is modeled as a networked control system of systems(So S)subjected to packet dropouts and delays. Next, an observerbased controller is designed to stabilize the system in presence of the aforementioned communication constraints and simulation results are provided to support the control design methodology.

关键词： microalternator microgrid systems networked control observer-based controller photovoltaic systems

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The Interaction between Control and Computing Theories:New Approaches

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International Journal of Automation and computing 2017年第3期14卷 254-274页

作者： magdi S.mahmoud Yuanqing Xia Systems Engineering Department KFUPM School of Automation Beijing Institute of Technology

Day by day, networked control system（NCS） methods have been promoted for distributed closed-loop control ***, the integration of control and computing theories enhanced the development of networked control systems through remote control for wide applications employing the internet. Two further directions to networked control technology are LeaderFollower systems and model predictive control systems. Cloud control system is looked at an extension of networked control systems（NCS） using internet of things（IOT） methodologies. In this paper, a comprehensive literature survey of the new technology of control systems application performed on cloud computing is presented.

关键词： Networked control system(NCS) cloud control system network constraints leader-follower system model predictive control

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LmI Consensus Condition for Discrete-time multi-agent Systems

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IEEE/CAA Journal of Automatica Sinica 2018年第2期5卷 509-513页

作者： magdi S.mahmoud Gulam Dastagir Khan Systems Engineering Department KFUPM E O. Box 5067 Dhahran 31261 Saudi Arabia

This paper examines a consensus problem in multiagent discrete-time systems, where each agent can exchange information only from its neighbor agents. A decentralized protocol is designed for each agent to steer all agents to the same vector. The design condition is expressed in the form of a linear matrix inequality. Finally, a simulation example is presented and a comparison is made to demonstrate the effectiveness of the developed methodology.

关键词： Index Terms-Consensus algorithms discrete-time systems linear matrix inequalities multi-agent systems.

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Adaptive and Predictive Control Strategies for Wind Turbine Systems: A Survey

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IEEE/CAA Journal of Automatica Sinica 2019年第2期6卷 364-378页

作者： magdi S.mahmoud mojeed O.Oyedeji the Systems Engineering Department King Fahd University of Petroleum and Minerals (KFUPM)

The wind turbine(WT) is a renewable energy conversion device for transformation of kinetic energy from the wind to mechanical energy for subsequent use in different *** paper focuses on wind turbine control design *** content is divided into the following parts: 1) An overview of the recent advances that have been made in the application of adaptive and model predictive control strategies for wind turbines. 2) Summarizes some important aspects of modeling of wind turbines for control studies. 3) Provides an outlook on the application of adaptive model predictive control for uncertain systems to stimulate new research interests for wind turbine systems. We provide an overall picture of the research results with evaluation of the merits/demerits.

关键词： Adaptive control model predictive control wind turbine(WT)

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Voltage imbalance mitigation in an active distribution network using decentralized current control

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Protection and Control of modern Power Systems 2023年第2期8卷 68-84页

作者： Ahmed m.m.Nour Ahmed A.Helal magdi m.El-Saadawi Ahmed Y.Hatata Alexandria Higher Institute of Engineering and Technology(AIET) AlexandriaEgypt Department of Electrical and Control Engineering Arab Academy for Science and Technology and Maritime TransportAlexandriaEgypt Department of Electrical Engineering Faculty of EngineeringMansoura UniversityMansouraEgypt Department of Electrical Engineering College of EngineeringShaqra UniversityShaqraKingdom of Saudi Arabia

Voltage imbalance(VI)is caused by the difference in connected single-phase load or generation in a low voltage distribution network(DN).VI increase in a smart distribution grid is due to the current practice of increasing single-phase distributed generators such as photovoltaic(PV)*** paper proposes a decentralized control method to mitigate VI using distributed batteries included in smart grid interfaced residential PV *** mitigate VI using the batteries in this way,five challenges must be overcome,i.e.,equalizing all battery stress currents within the DN,mitigating VI in abnormal conditions such as signal loss among bus controllers,being immune from the distorted feedback measurements,minimizing the steady-state error at different loads,and overcoming the insufficient number or capacity of the distributed batteries at the same *** fuzzy logic controllers(FLC)are proposed at each bus to overcome these five tasks based on a decentralized control *** proposed decentralized control based on FLC is compared with centralized control based on a PI *** proposed control method is tested and verified using simulations in the mATLAB/Simulink software,and the results validate the ability of the scheme to alleviate VI on a smart distribution network under both normal and abnormal conditions.

关键词： Fuzzy controller Distributed batteries Decentralized control Voltage imbalance Distributed PV

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mitigating diabetes-related complications:Empowering metformin with cholecalciferol and taurine supplementation in type 2 diabetic rats

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World Journal of Diabetes 2024年第8期15卷 1778-1792页

作者： mai S Attia Fadwa Ayman mohamed S Attia Galal Yahya mansour H Zahra magdi mohamed Ibrahim Khalil abdel Aziz A Diab Department of Zoology Faculty of ScienceZagazig 44519Egypt Department of Pharmaceutics Faculty of PharmacyZagazig 44519Egypt Department of microbiology and Immunology Faculty of PharmacyZagazig UniversityZagazig 44519Egypt Department of Biochemistry Faculty of MedicineZagazig 44519Egypt

BACKGROUND Type 2 diabetes is one of the most prevalent chronic diseases worldwide,significantly impacting patients'quality of *** treatment options like metformin(mET)effectively counteract hyperglycemia but fail to alleviate diabetes-associated complications such as retinopathy,neuropathy,nephropathy,hepatopathy,and cardiovascular *** To propose the supplementation of cholecalciferol(CHO)and taurine(TAU)to enhance mET efficacy in controlling diabetes while minimizing the risk of associated *** The study involved sixty rats,including ten non-diabetic control rats and fifty experimental rats with type 2 diabetes induced by *** experimental rats were further subdivided into positive control and treatment *** four treatment groups were randomly allocated to a single mET treatment or mET combined with supplements either CHO,TAU,or *** Diabetic rats exhibited elevated levels of glucose,insulin,Homeostasis model Assessment of Insulin Resistance(HOmA-IR),glycated hemoglobin percentage,lipid markers,aspartate aminotransferase,and malondialdehyde,along with reduced levels of antioxidant enzymes(catalase and superoxide dismutase).The administration of CHO and TAU supplements alongside mET in diabetic rats led to a noticeable recovery of islet *** antioxidative,anti-inflammatory,and anti-apoptotic properties of the proposed combination therapy significantly ameliorated the aforementioned *** The supplementation of CHO and TAU with mET showed the potential to significantly improve metabolic parameters and protect against diabetic complications through its antioxidative,anti-inflammatory,and antiapoptotic effects.

关键词： Diabetes complications metformin Cholecalciferol Taurine Glycated hemoglobin% Antioxidant

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