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Live above-and belowground biomass of a Mozambican evergreen forest:a comparison of estimates based on regression equations and biomass expansion factors

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Forest Ecosystems 2016年第1期3卷 1-12页

作者： Tarquinio Mateus magalh.es Departamento de Engenharia Florestal Universidade Eduardo MondlaneCampus Universitario

Background： Biomass regression equations are claimed to yield the most accurate biomass estimates than biomass expansion factors （BEFs）. Yet, national and regional biomass estimates are generally calculated based on BEFs, especially when using national forest inventory data. Comparison of regression equations based and BEF-based biomass estimates are scarce. Thus, this study was intended to compare these two commonly used methods for estimating tree and forest biomass with regard to errors and biases. Methods： The data were collected in 2012 and 2014. In 2012, a two-phase sampling design was used to fit tree component biomass regression models and determine tree BEFs. In 2014, additional trees were felled outside sampling plots to estimate the biases associated with regression equation based and BEF-based biomass estimates; those estimates were then compared in terms of the following sources of error： plot selection and variability, biomass model, model parameter estimates, and residual variability around model prediction. results： The regression equation based below-, aboveground and whole tree biomass stocks were, approximately, 7.7, 8.5 and 8.3 % larger than the BEF-based ones. For the whole tree biomass stock, the percentage of the total error attributed to first phase （random plot selection and variability） was 90 and 88 % for regression- and BEF-based estimates, respectively, being the remaining attributed to biomass models （regression and BEF models, respectively）. The percent bias of regression equation based and BEF-based biomass estimates for the whole tree biomass stock were -2.7 and 5.4 %, respectively. The errors due to model parameter estimates, those due to residual variability around model prediction, and the percentage of the total error attributed to biomass model were larger for BEF models （than for regression models）, except for stem and stem wood components. Conclusions＂ The regression equation based biomass stocks were found to be slightly larg

关键词： Androstachysjohnsonii Prain Mecrusse root growth Biomass additivity Double sampling Forest biomassinventory Carbon allocation

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Enteric nervous system and inflammatory bowel diseases:Correlated impacts and therapeutic approaches through the P2X7 receptor

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World Journal of Gastroenterology 2021年第46期27卷 7909-7924页

作者： Henrique Inhauser riceti magalh.es Patricia Castelucci Department of Surgery School of Veterinary Medicine and Animal SciencesUniversity of São PauloSão Paulo 08000-000Brazil Department of Anatomy Institute of Biomedical SciencesUniversity of São PauloSão Paulo 08000-000Brazil

The enteric nervous system(ENS)consists of thousands of small ganglia arranged in the submucosal and myenteric plexuses,which can be negatively affected by Crohn’s disease and ulcerative colitis-inflammatory bowel diseases(IBDs).IBDs are complex and multifactorial disorders characterized by chronic and recurrent inflammation of the intestine,and the symptoms of IBDs may include abdominal pain,diarrhea,rectal bleeding,and weight *** P2X7 receptor has become a promising therapeutic target for IBDs,especially owing to its wide expression and,in the case of other purinergic receptors,in both human and model animal enteric ***,little is known about the actual involvement between the activation of the P2X7 receptor and the cascade of subsequent events and how all these activities associated with chemical signals interfere with the functionality of the affected or treated *** this review,an integrated view is provided,correlating the structural organization of the ENS and the effects of IBDs,focusing on cellular constituents and how therapeutic approaches through the P2X7 receptor can assist in both protection from damage and tissue preservation.

关键词： Chemical coding Enteric nervous system Gastroenterology Inflammatory bowel diseases P2X7 receptor Purinergic signaling

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Importance of neonatal screening:A case study of sickle cell disease and cystic fibrosis coexistence

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World Journal of Clinical Pediatrics 2025年第1期14卷 113-118页

作者： Nathalia Noyma Sampaio magalh.es Lucas Barra Mathiasi Daniela de Oliveira Werneck rodrigues Department of Pediatrics Faculdade de Ciências Médicas e da Saúde de Juiz de ForaJuiz de Fora 36033-003Brazil Department of Internal Medicine Rede D'Or Rio de JaneiroRio de Janeiro 22270-010Brazil Department of Hematology Fundação HemominasJuiz de Fora 36010-560MGBrazil Department of Internal Medicine Universidade Presidente Antônio Carlos-Faculdade de Medicina Juiz de ForaJuiz de Fora 36010-560Minas GeraisBrazil

BACKGrOUND Neonatal screening(NS)is a public health policy to identify genetic pathologies such as cystic fibrosis(CF),sickle cell disease,and other *** cell disea-se is the comprehensive term for a group of hemoglobinopathies characterized by the presence of hemoglobin *** is an autosomal recessive multisystemic disease with pathophysiology involving deleterious mutations in the transmembrane re-gulatory gene that encodes a protein that regulates the activity of chloride and sodium channels in the cell surface *** is crucial for early diagnosis and management,which ensures a better quality of *** To report a case of the coexistence of sickle cell anemia(SCA)and CF and perform an integrative literature *** This is an observational study and a review of the literature focusing on two rare genetic pathologies identified simultaneously in NS from the perspective of a clinical *** authors identified only 5 cases of SCA associated with *** clinical trials or review articles were identified considering the rarity of the coexistence of these two *** Herein,the authors reported the case of a girl who after undergoing NS on day 8 of life was diagnosed with SCA with an alteration in the dosage of immunoreactive *** diagnosis of CF was confirmed by the Coulometry Sweat *** rarity of the co-occurrence of these two severe genetic pathologies(CF and SCA)is a challenge for medical *** This study adds to the few case reports present in the literature that highlight the identification of two severe diseases via NS.

关键词： Sickle cell disease Sickle cell anemia Children Cystic fibrosis Neonatal Screening Case reports

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Bird habitat preferences drive hemoparasite infection in the Neotropical region

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Integrative Zoology 2021年第5期16卷 755-768页

作者： Gabriel Massaccesi DE LA TOrrE Karla magalh.es CAMPIÃO Biological Interactions Departamento de ZoologiaUniversidade Federal do ParanáCuritibaBrazil Programa de Pós-graduação em Ecologia e Conservação Universidade Federal do ParanáCuritibaBrazil

The role that the environment plays in vector-borne parasite infection is one of the central factors for understanding disease *** assessed how Neotropical bird foraging strata and habitat preferences determine infection by parasites of the genera Haemoproteus,Plasmodium,Leucocytozoon,and Trypanosoma and filarioids,and tested for phylogenetic signal in these host-parasite *** performed extensive searches of the scientific literature and created a database of hemoparasite *** collected data on host body mass,foraging strata,habitat preference,and migratory status,and tested if host ecological traits predict each hemoparasite occurrence and prevalence using a phylogenetic Bayesian *** of Plasmodium tend to infect birds from tropical forests while birds from altitudinal environments are likely to be infected by species of *** probability of a bird being infected by filarioid or Trypanosoma is higher in lowland *** species that occur in anthropic environments and dry habitats of tropical latitudes are more susceptible to infection by species of *** foraging strata is also influential and bird species that forage in the mid-high and canopy strata are more prone to infection by species of Haemoproteus and *** also identified phylogenetic signal for host-parasite associations with the probability of infection of Neotropical birds by any hemoparasite being more similar among more closely related *** provided a useful framework to identify environments that correlate with hemoparasite infection,which is also helpful for detecting areas with potential suitability for hemoparasite infection due to land conversion and climate change.

关键词： habitat use haemosporidians host-parasite interaction migratory birds prevalence

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Olfactory dysfunction in dementia

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World Journal of Clinical Cases 2014年第11期2卷 661-667页

作者： Jorge Alves Agavni Petrosyan rosana magalh.es Cognitive rehabilitation Center 4710-228 Braga Portugal Department of Cognitive Sciences Univer-sity of California at Irvine Irvine CA 92717 United States

The natural aging process brings about some inevitable consequences, such as olfactory dysfunction, which is also frequently linked to numerous neurodegenerative disorders. Many age-related dementia, such as Alzheimer's disease, Vascular dementia, Parkinson's disease, and Frontotemporal Dementia often display olfactory dysfunction. Despite the overwhelming evidence of above mentioned facts, the symptomatic relevance and potential clinical and pre-clinical value of olfactory dysfunction remains overlooked by many clinicians and public alike. Olfactory dysfunction has strong practical implications on daily activities and, although not as prominent as in other mammals, olfaction is still an evolutionarily relevant sense involved in human survival(e.g., smelling gas; bad food). In this work, we provide a brief review of current research related to the olfactory dysfunction profiles in different types of dementia. Additionally, we present a compilation of accessible, easy to use olfaction assessment tools; and highlight future directions in terms of improving clinical diagnosis in patient care and research.

关键词： Dementia Aging Olfaction Olfactory dysfunction

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Archean-Ediacaran evolution of the Campos Gerais Domain-A reworked margin of the São Francisco paleocontinent(SE Brazil):Constraints from metamafic-ultramafic rocks

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Geoscience Frontiers 2022年第5期13卷 286-308页

作者： Marco Aurélio Piacentini Pinheiro George L.Guice Joana reis magalh.es Geological Survey of Brazil–CPrM Av Brazil 1731Belo Horizonte 30140-002Brazil Department of Mineral Sciences National Museum of Natural HistorySmithsonian Institution10th Street and Constitution Avenue NWWashington D.C.20560USA

The Campos Gerais Domain(CGD)in southeastern Brazil is an approximately 180 km×35 km area of Archean–Proterozoic rocks located southwest of the São Francisco Craton(SFC).The Archean–Paleopro terozoic evolution of the CGD—alongside its potential correlation with the SFC or other cratonic blocks in the region-is currently *** present the results of systematic petrography,bulkrock geochemistry,mineral chemistry and geochronology for a suite of scarcely studied mafic–ultramafic rocks from the *** also provide a compilation of previously reported bulk-rock geochemical and spinel group mineral chemical data for mafic–ultramafic rocks throughout the CGD,and geochronological information for various lithotypes in the *** CGD records a protracted Mesoarchean to Statherian(3.1–1.7 Ga)crustal evolution,which we interpret to share a common history with the southern SFC and their related reworked segments,suggesting that it is a westward extension of this cratonic *** metavolcano-sedimentary rocks of the Fortaleza de Minas and Alpinópolis segments represent a Mesoarchean greenstone belt that is stratigraphically and chemically comparable to Archean greenstone belts worldwide,and that is broadly coeval with a local suite of tonalite-trondhjemite-grano diorite(TTG)gneisses and migmatites.U-Pb SHrIMP zircon data from a subalkaline metagabbro yielded a concordia age of ca.2.96 Ga,revealing a previously unrecognized phase of Archean magmatism in the CGD that can be chrono-correlated with metakomatiite and TTG generation elsewhere in the São Francisco *** data contradict a hypothesis whereby the metavolcano-sedimentary rocks of the Jacuí-Bom Jesus da Penha and Petúnia segments represent an ophiolite,as previously suggested,instead presenting features that point to formation in association with a continental *** with a U-Pb(SHrIMP)crystallization age of ca.2.13 Ga recorded by zircon grains from a metaultramafic rock,these data h

关键词： Komatiites São Francisco Craton Southern Brasília Orogen Archean geodynamics rhyacian orogeny

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Is the EGFr pathway relevant for the pathogenesis but not for treatment of acute myeloid leukemia?

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Journal of Cancer Metastasis and Treatment 2021年第1期7卷 765-774页

作者： Luciana Yamamoto de Almeida Eduardo magalh.es rego Center for Cell-based Therapy University of Sao PauloRibeirao PretoSao Paulo CEP 14051-140Brazil Hematology Division LIM31Faculdade de MedicinaUniversity of Sao PauloSao Paulo CEP 05403-000Brazil.

Despite intense research and the development of several new chemotherapeutics,the prognosis for specific subsets of acute myeloid leukemia(AML)has not improved ***,the investigation of signaling pathways associated with the pathogenesis and progression of AML has become a source for the discovery of more effective *** epidermal growth factor receptor(EGFr)belongs to the HEr family of tyrosine kinase(TK)receptors and is involved in the progression of a variety of solid *** the expression of members of the HEr family appears to be limited to epithelial tissues and derived neoplasms,there is evidence demonstrating their role in hematopoiesis and hematological *** AML,preclinical studies and two anecdotal cases of response to EGFr TK inhibitors(TKI)supported the EGFr signaling pathway as a potential therapeutic ***,the presence of EGFr ligands in the bone marrow microenvironment has been shown to play pathological and regenerative/protective roles in ***,data reporting the expression of EGFr in AML remain controversial and the EGFr pathway inhibition in AML patients has demonstrated limited clinical *** studies are required to determine the relevance of the EGFr pathway in AML biology and which patients may benefit from using EGFr TKI or other drugs that target TK receptors.

关键词： Acute myeloid leukemia epidermal growth factor receptor EGFr ligands EGFr tyrosine kinase inhibitors gefitinib erlotinib

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Tritrichomonas foetus:New structures by high-resolution scanning helium ion microscopy

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BIOCELL 2021年第2期45卷 259-266页

作者： MArLENE BENCHIMOL ABIGAIL MIrANDA-magalh.es ANTONIO PErEIrA-NEVes WANDErLEY DE SOUZA Universidade do Grande rio Duque de Caxias25071-202Rio de Janeiro Departamento de Microbiologia Laboratório de Biologia Celular de PatógenosFiocruzInstituto Aggeu MagalhãesRecife52060-269Brazil Universidade Federal do rio de Janeiro Instituto de Biofísica Carlos Chagas FilhoLaboratório de Ultraestrutura Celular Hertha Meyer Instituto Nacional de Ciência e Tecnologia(INBEB)and Centro Nacional de Biologia Estrutural e Bioimagens(CENABIO)Rio de Janeiro21941-902Brazil

Helium ion scanning microscopy(HIM)is a novel high-resolution scanning microscopy technique that uses helium ions instead of electrons to form images of the highest quality and resolution,providing a sub-nanometer resolution sputter uncoated biological ***,we took advantage of HIM to explore the cell surface of Tritrichomonas foetus,a protist parasite of cattle that provokes hard infection and abortion in *** describe thin protrusions,like nanotubes described in other cells,with different sizes(27 nm to 81 nm in thickness)and various lengths(from 73 nm to 2μm),as well bulbous structures either budding from the cell surface or present in the extremities of some *** flagella also presented these thin protrusions and different protein decoration,similar to those previously described using freeze-fracture *** between two cells were also seen,and their role in infection is *** cell surface was also examined and showed several pits indicative of endocytic activity and other types of arrays of *** observations were confirmed using Scanning Electron Microscopy(SEM),negative staining,and conventional thin sectioning for observation by transmission electron *** findings provide new and relevant information that may contribute to a better understanding of protozoan biology and its interaction with mammalian cells.

关键词： Nanotubes Microvesicles Surface specializations

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Coarse to Fine: The role of Severe Plastic Deformation in Advancing Titanium-Based Medical Implants - A Comprehensive review

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Journal of Wuhan University of Technology(Materials Science) 2025年第1期40卷 295-306页

作者： Dragana r Mihajlović Bojan I Međo Ivana Lj Cvijović-Alagić Veljko r Djokić Faculty of Technology and Metallurgy University of BelgradeKarnegijeva 411120 BelgradeSerbia Vinča Institute of Nuclear Sci-ences-National Institute of the republic of Serbia University of Belgrade11001BeogradSerbia Innovation Centre of the Faculty of Technology and Metallurgy Karnegijeva 411120 BelgradeSerbia

This paper describes severe plastic deformation(SPD)procedures,which are utilized to form an ultrafine-grained structure in metallic *** the SPD process,a solid material sample is subjected to very high loads without a significant change in sample *** the present work,the high-pressure torsion(HPT)process,as one of the SPD techniques,which achieves a high degree of deformation and ensures refinement of the microstructure,will be discussed in more *** that grain size control is accepted as a method to obtain materials with desired characteristics,an overview of the properties of ultrafine-grained titanium-based biomaterials to be used in medicine is ***,particular attention is dedicated to the influences of HPT process parameters,primarily hydrostatic pressure,and number of revolutions during torsion,on the grain size and physical and mechanical characteristics(modulus of elasticity,microhardness,and tensile properties),corrosion resistance,and biocompatibility of the titanium-based biomaterials.A review of the literature indicates that titanium-based materials obtained by the SPD process show improved mechanical and physical properties without losing biocompatibility and corrosion resistance,which suggests that these methods of obtaining implants are something that should be further developed in the future.

关键词： high-pressure torsion process ultrafine-grained titanium-based materials electrochemical anodization physical properties mechanical properties

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The roles of anurans in antagonistic networks are explained by life-habit and body-size

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Integrative Zoology 2022年第4期17卷 530-542页

作者： Amanda Caroline DUDCZAK Gabriel Massaccesi DE LA TOrrE Lorena EUCLYDes Karla magalh.es CAMPIÃO Department of Zoology Federal University of ParanáCuritibaBrazil Postgraduate Program in Zoology Federal University of ParanáCuritibaBrazil Postgraduate Program in Ecology and Conservation Federal University of ParanáCuritibaBrazil

Interactions among living beings are the structuring basis of ecosystems,and studies of networks allow us to identify the patterns and consistency of such *** networks reflect the energy flow of communities,and identifying network structure and the biological aspects that influence its stability is crucial to understanding ecosystem *** used antagonistic anuran interactions-predator-prey and host-parasite-to assess structural patterns and to identify the key anuran species structuring these *** tested whether anuran body-size and life-habit are related to their roles in these *** collected individuals of 9 species of anurans from an area of the Atlantic Forest in Brazil and identified their prey and helminth *** used network(modularity,specialization,and nestedness)and centrality metrics(degree,closeness,and betweenness)to identify the role of anuran species in both *** then evaluated whether anuran body-size or life-habit were related to anuran centrality using generalized linear mixed *** networks formed specialized interactions in compartments composed by key species from different *** our networks,anurans with rheophilic and cryptozoic habit are central in predator-prey networks,and those with larger body size and arboreal and cryptozoic habit in the host-parasite *** study represents a step towards a better understanding of the influential factors that affect the structure of anuran antagonist networks,as well as to recognize the functioning roles of anuran species.

关键词： diet disease food web helminth infection network centrality

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