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Analysis of b→cτν¯_(τ)anomalies using weak effective Hamiltonian with complex couplings and their impact on various physical observables

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Chinese Physics C 2024年第8期48卷 56-75页

作者： muhammad Arslan Tahira Yasmeen Saba Shafaq Ishtiaq Ahmed muhammad jamil Aslam Department of Physics Quaid-i-Azam UniversityIslamabad 45320Pakistan Department of Physics International Islamic UniversityIslamabad 44000Pakistan National Center for Physics Islamabad 44000Pakistan

Recently,the experimental measurements of the branching ratios and different polarization asymmetries for processes occurring through flavor-changing-charged current(b→cτν¯_(τ))transitions by BABAR,Belle,and LHCb have revealed some significant differences from the corresponding Standard Model(SM)*** has triggered an interest to search for physics beyond the SM in the context of various new physics(NP)models and using the model-independent weak effective Hamiltonian(WEH).Assuming left-handed neutrinos,we add the dimension-six vector,(pseudo-)scalar,and tensor operators with complex Wilson coefficients(WCs)to the SM *** 60%,30%,and 10%constraints resulting from the branching ratio of B_(c)→τν¯_(τ),we reassess the parametric space of these new physics WCs accommodating the current anomalies based on the most recent HFLAV data of R_(τ/μ,e)(D)and R_(τ/μ,e)(D^(*))and Belle data of F_(L)(D^(*))and P_(τ)(D^(*)).We find that the allowed parametric region of left-handed scalar couplings strongly depends on the constraints of the B_(c)→τν¯_(τ)branching ratio,and the maximum pull from the SM predictions results from the<60%branching ratio ***,the parametric region changes significantly if we extend the analysis by adding LHCb data of R_(τ/μ)(J/ψ)and R_(τ/ℓ)(Λ_(c)).Furthermore,due to the large uncertainties in the measurements of R_(τ/μ)(J/ψ)and R_(τ/ℓ)(X_(c)),we derive the sum rules which complement them with R_(τ/μ,e)(D)and R_(τ/μ,e)(D^(*)).Using the best-fit points of the new complex WCs along with the latest measurements of R_(τ/μ,e)(D(^(*))),we predict the numerical values of the observable R_(τ/ℓ)(Λ_(c)),R_(τ/μ)(J/ψ),and R_(τ/ℓ)(X_(c))from the sum *** simultaneous dependence of abovementioned physical observables on the NP WCs is established by plotting their correlation with R_(D) and R_(D^(*)),which are useful to discriminate between various NP *** find that the most significant impact of NP results from the WC C^(S)_(L)=4C^(T).Fi

关键词： B meson anomalies new physics complex coupling HFLAV

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Effect of Light Emitting Diodes (LEDs) on Growth, Mineral Composition, and Nutritional Value of Wheat & Lentil Sprouts

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Phyton-International Journal of Experimental Botany 2024年第6期93卷 1117-1128页

作者： Abdul Momin Amana Khatoon Wajahat Khan Dilsat Bozdoğan Konuşkan muhammad Mudasar Aslam muhammad jamil Shafiq Ur Rehman Baber Ali Alevcan Kaplan Sana Wahab muhammad Nauman Khan Sezai Ercisli Mohammad Khalid Al-Sadoon Department of Botany Kohat University of Science&TechnologyKohat26000Pakistan Department of Food Engineering Faculty of AgricultureHatay Mustafa Kemal UniversityHatay31000Türkiye Department of Botany University of Science&TechnologyBannu28100Pakistan Department of Biotechnology and Genetic Engineering Kohat University of Science&TechnologyKohat26000Pakistan Department of Biology University of HaripurKhyber Pakhtunkhwa22620Pakistan School of Science Western Sydney UniversityPenrithNew South Wales2151Australia Department of Crop and Animal Production Sason Vocational SchoolBatman UniversityBatman72060Türkiye Department of Plant Sciences Quaid-i-Azam UniversityIslamabad45320Pakistan Department of Botany Islamia College PeshawarPeshawar25120Pakistan Department of Horticulture Agricultural FacultyAtaturk UniversityErzurum25240Türkiye HGF Agro Ata TeknokentErzurumTR-25240Türkiye Department of Zoology College of ScienceKing Saud UniversityRiyadh11451Saudi Arabia

Sprouts are ready-to-eat and are recognized worldwide as functional components of the human *** advances in innovative agricultural techniques could enable an increase in the production of healthy *** use of light-emitting diode(LED)in indoor agricultural production could alter the biological feedback loop,increasing the functional beneﬁts of plant foods such as wheat and lentil sprouts and promoting the bioavailability of *** effects of white(W),red(R),and blue(B)light were investigated on the growth parameters and nutritional value of wheat and lentil *** the laboratory,seeds were sown under three different LED treat-ments:white,red,and blue light,while normal incandescent light served as a *** seed germina-tion improved by 18.34%and 12.67%for wheat and 18.34%and 12.67%for lentil sprouts under LED treatments R and B,*** increase in total soluble protein and sugar by 33.4%and 9.23%in wheat and by 31.5%and 5.87%in lentils was observed under the R LED *** C concentrations in wheat and lentils were signiﬁcantly increased by R LED compared to all other *** parameters,including potassium and sodium concentrations,were signiﬁcantly increased under red and blue light compared to the control;white light,on the other hand,signiﬁcantly decreased all these *** to the experimental data,red and blue LED light could be beneﬁcial in the production of functional wheat and lentil sprouts with high nutrient concentrations.

关键词： Growth parameters LED nutritional value sprouts total soluble proteins

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Observability of parameter space for charged Higgs boson in its bosonic decays in two Higgs doublet model Type-1

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Chinese Physics C 2024年第2期48卷 57-65页

作者： Ijaz Ahmed Waqas Ahmad M.S.Amjad jamil muhammad Federal Urdu University of Arts Science and TechnologyIslamabad Pakistan Riphah International University Sector I-14Hajj ComplexIslamabad Pakistan National University of Technology Islamabad Pakistan Sang-Ho College and Department of PhysicsKonkuk UniversitySeoul 05029South Korea

This study explores the possibility of discovering H±through its bosonic decays,i.e.,H±→W±φ(whereφ=h or A),within the Type-I two Higgs doublet model(2HDM).The main objective is to demonstrate the available parameter space after applying recent experimental and theoretical exclusion *** suggest that mH±=150 GeV is the most probable mass for the H±→W±φdecay channel in pp collisions at s1/2=8,13,and 14 *** also report on the application of a modern machine learning approach to a multivariate technique for heavy charged Higgs production in association with a single top quark through weak interaction to demonstrate its observability in comparison with the most relevant Standard Model backgrounds using the neural networks of boosted decision Tree(BDT),likelihood(LH),and multilayer perceptron(MLP).

关键词： charged Higgs MSSM LHC

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Identifying and validating MMP family members(MMP2,MMP9,MMP12,and MMP16)as therapeutic targets and biomarkers in kidney renal clear cell carcinoma(KIRC)

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Oncology Research 2024年第4期32卷 737-752页

作者： KUNLUN LI DANDAN LI BARBOD HAFEZ MOUNIR M.SALEM BEKHIT YOUSEF A.BIN JARDAN FARS KAED ALANAZI EHAB I.TAHA SAYED H.AUDA FAIQAH RAMZAN muhammad jamil The Second Affiliated Hospital of Harbin Medical University Harbin Medical UniversityHarbinChina Department of Pharmaceutical Engineering Jiangsu Ocean UniversityLianyungangChina Department of Biological Engineering University of SalfordSalfordUK Department of Pharmaceutics College of PharmacyKing Saud UniversityRiyadhSaudi Arabia Department of Animal and Poultry Production Faculty of Veterinary and Animal SciencesGomal UniversityDera Ismail KhanPakistan Department of Arid Zone Research PARC instituteDera Ismail KhanPakistan

Kidney Renal Clear Cell Carcinoma(KIRC)is a malignant tumor that carries a substantial risk of morbidity and *** MMP family assumes a crucial role in tumor invasion and *** study aimed to uncover the mechanistic relevance of the MMP gene family as a therapeutic target and diagnostic biomarker in Kidney Renal Clear Cell Carcinoma(KIRC)through a comprehensive approach encompassing both computational and molecular ***,Cytoscape,UALCAN,GEPIA,OncoDB,HPA,cBioPortal,GSEA,TIMER,ENCORI,DrugBank,targeted bisulfite sequencing(bisulfite-seq),conventional PCR,Sanger sequencing,and RT-qPCR based analyses were used in the present study to analyze MMP gene family members to accurately determine a few hub genes that can be utilized as both therapeutic targets and diagnostic biomarkers for *** performing STRING and Cytohubba analyses of the 24 MMP gene family members,MMP2(matrix metallopeptidase 2),MMP9(matrix metallopeptidase 9),MMP12(matrix metallopeptidase 12),and MMP16(matrix metallopeptidase 16)genes were denoted as hub genes having highest degree *** analyzing MMP2,MMP9,MMP12,and MMP16 via various TCGA databases and RT-qPCR technique across clinical samples and KIRC cell lines,interestingly,all these hub genes were found significantly overexpressed at mRNA and protein levels in KIRC samples relative to *** notable effect of the up-regulated MMP2,MMP9,MMP12,and MMP16 was also documented on the overall survival(OS)of the KIRC ***,targeted bisulfite-sequencing(bisulfite-seq)analysis revealed that promoter hypomethylation pattern was associated with up-regulation of hub genes(MMP2,MMP9,MMP12,and MMP16).In addition to this,hub genes were involved in various diverse oncogenic *** MMP gene family members(MMP2,MMP9,MMP12,and MMP16)may serve as therapeutic targets and prognostic biomarkers in KIRC.

关键词： KIRC MMP gene family Chemotherapy Overall survival

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Managing Software Testing Technical Debt Using Evolutionary Algorithms

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Computers, Materials & Continua 2022年第10期73卷 735-747页

作者： muhammad Abid jamil Mohamed K.Nour Department of Computer Science Umm Al-Qura UniversityMakkahSaudi Arabia

Technical debt(TD)happens when project teams carry out technical decisions in favor of a short-term goal(s)in their projects,whether deliberately or *** must be properly managed to guarantee that its negative implications do not outweigh its advantages.A lot of research has been conducted to show that TD has evolved into a common problem with considerable financial *** technical debt is the technical debt aspect of testing(or test debt).Test debt is a relatively new concept that has piqued the curiosity of the software industry in recent *** this article,we assume that the organization selects the testing artifacts at the start of every *** the latest features in consideration of expected business value and repaying technical debt are among candidate tasks in terms of the testing process(test cases increments).To gain the maximum benefit for the organization in terms of software testing optimization,there is a need to select the artifacts(i.e.,test cases)with maximum feature coverage within the available *** management of testing optimization for large projects is complicated and can also be treated as a multi-objective problem that entails a trade-off between the agile software’s short-term and long-term *** this article,we implement a multi-objective indicatorbased evolutionary algorithm(IBEA)for fixing such optimization *** capability of the algorithm is evidenced by adding it to a real case study of a university registration process.

关键词： Technical debt software testing optimization large scale agile projects evolutionary algorithms multiobjective optimization indicatorbased evolutionary algorithm(IBEA) pareto front

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Entropies of the Y-Junction Type Nanostructures

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Computer Modeling in Engineering & Sciences 2023年第6期135卷 2665-2679页

作者： Ricai Luo Aisha Javed muhammad Azeem muhammad Kamran jamil Hassan Raza muhammad Yasir Ilyas School of Mathematics and Physics Hechi UniversityYizhou456300China Abdus Salam School of Mathematical Sciences Government College UniversityLahore54000Pakistan Department of Mathematics Riphah Institute of Computing and Applied SciencesRiphah International UniversityLahore54000Pakistan School of Mathematical Sciences College of Science and TechnologyWenzhou-Kean UniversityWenzhou325060China Department of Physics COMSATS University IslamabadLahore54000Pakistan

Recent research on nanostructures has demonstrated their importance and application in a variety of *** are used directly or indirectly in drug delivery systems,medicine and pharmaceuticals,biological sensors,photodetectors,transistors,optical and electronic devices,and so *** discovery of carbon nanotubes with Y-shaped junctions is motivated by the development of future advanced electronic *** of their interactionwithY-junctions,electronic switches,amplifiers,and three-terminal transistors are of particular *** is a concept that determines the uncertainty of a system or *** concepts are also used in biology,chemistry,and applied *** on the requirements,entropy in the form of a graph can be classified into several *** 1955,graph-based entropy was *** of the types of entropy is edgeweighted *** examined the abstract form of Y-shaped junctions in this *** edge-weight-based entropy formulas for the generic view of Y-shaped junctions were created,and some edge-weighted and topological index-based concepts for Y-shaped junctions were discussed in the present paper.

关键词： Y-shaped junctions three-terminal junctions nanostuctures entropy carbon nanotube

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Some Topological Values of Supramolecular Chain of Different Complexes of N-Salicylidene-L-Valine

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Computer Modeling in Engineering & Sciences 2023年第8期136卷 1899-1916页

作者： Yonghong Liu muhammad Waheed Umair Saleem muhammad Kamran jamil muhammad Naveed Mohammad Reza Farahani School of Computer Science Chengdu UniversityChengduChina Punjab School Education Department Govt Higher Secondary School Nangal Sahdan MuridkeSheikhupuraPakistan Muslim Model Girls Higher Secondary School Zafarwal NarowalPakistan Department of Mathematics Riphah International UniversityLahorePakistan School of Packaging Michigan State UniversityEast LansingUSA Department of Mathematics Iran University of Science and Technology(IUST)NarmakTehranIran

L-valine is a glycogen-type amino acid regarded among the necessary mammalian amino *** is an amino acid that is essential for protein synthesis.N-salicylidene-L-valine is gaining a lot of attention because of its unique structure and increased catalytic and cytotoxic *** explore the chain of supramolecular dialkyltin N-salicylidene-L-valine complexes 2,3,and 4 to learn more about this structure and its features regarding topological *** computed the first and second Randi′c index,harmonic index,sum-connectivity index,atom-bond-connectivity index,geometric arithmetic index and reduced reciprocal Randi′c index of Supramolecular Chain of Different Complexes of ***,we present an analysis of such structures using specific examples,as well as a comparison of topological indices.

关键词： Molecular compounds supramolecular chains topological indices

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Maintain Optimal Configurations for Large Configurable Systems Using Multi-Objective Optimization

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Computers, Materials & Continua 2022年第11期73卷 4407-4422页

作者： muhammad Abid jamil Deafallah Alsadie Mohamed K.Nour Normi Sham Awang Abu Bakar Department of Computer Science Umm Al-Qura UniversityMakkahSaudi Arabia Kulliyyah of Information and Communication Technology International Islamic UniversityMalaysia

To improve the maintenance and quality of software product lines,efficient configurations techniques have been ***,due to the complexity of derived and configured products in a product line,the configuration process of the software product line(SPL)becomes timeconsuming and *** product line consists of a various number of feature models that need to be *** different approaches have been presented by Search-based software engineering(SBSE)to resolve the software engineering issues into computational solutions using some metaheuristic ***,multiobjective evolutionary algorithms help to optimize the configuration process of *** this paper,different multi-objective Evolutionary Algorithms like Non-Dominated Sorting Genetic algorithms II(NSGA-II)and NSGA-III and Indicator based Evolutionary Algorithm(IBEA)are applied to different feature models to generate optimal results for large *** proposed approach is also used to generate the optimized test suites with the help of different multi-objective Evolutionary Algorithms(MOEAs).

关键词： Software product line search-based software engineering metaheuristic multiobjective evolutionary algorithms feature model

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Metabolomics in drug discovery: Restoring antibiotic pipeline

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亚太热带生物医学杂志:英文版 2023年第9期13卷 378-383页

作者： Faiza Azhar Mariam Busharat Shah Rukh Arshad Chaudhary Zainab Waheed muhammad Nauman jamil Department of Pharmaceutical Chemistry Punjab University College of PharmacyUniversity of the PunjabLahorePakistan School of Medical Indigenous and Health SciencesUniversity of WollongongNew South WalesAustralia Department of General Surgery Lahore General HospitalLahorePakistan Department of Pharmaceutical Chemistry Hamza College of PharmacyLahorePakistan

Metabolomics has emerged as a valuable tool in drug discovery and development,providing new insights into the mechanisms of action and toxicity of potential therapeutic *** focuses on the comprehensive analysis of primary as well as secondary metabolites,within biological *** provides a comprehensive understanding of the metabolic changes that occur within microbial pathogens when exposed to therapeutic agents,thus allowing for the identification of unique metabolic targets that can be exploited for therapeutic *** approach can also uncover key metabolic pathways essential for survival,which can serve as potential targets for novel *** analyzing the metabolites produced by diverse microbial communities,metabolomics can guide the discovery of previously unexplored sources of *** review explores some examples that enable medicinal chemists to optimize drug structure,enhancing efficacy and minimizing toxicity via metabolomic approaches.

关键词： Metabolomics Infectious diseases Drug discovery Antibiotics Biomarkers

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Biological Stability of Water-Based Cutting Fluids:Progress and Application

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Chinese Journal of Mechanical Engineering 2022年第1期35卷 7-30页

作者： Lizhi Tang Yanbin Zhang Changhe Li Zongming Zhou Xiaolin Nie Yun Chen Huajun Cao Bo Liu Naiqing Zhang Zafar Said Sujan Debnath muhammad jamil Hafiz muhammad Ali Shubham Sharma School of Mechanical and Automotive Engineering Qingdao University of TechnologyQingdao 266520China Hanergy(Qingdao)Lubrication Technology Co. Ltd.Qingdao 266200China Nanjing Kerun Lubricants Co. Ltd.Nanjing 211106China Chengdu Tool Research Institute Co. LtdChengdu 610500China School of Mechanical Engineering Chongqing UniversityChongqing 400044China Sichuan Future Aerospace Industry LLC Shifang 618400China Shanghai Jinzhao Energy Saving Technology Co. Ltd.Shanghai 200436China Department of Sustainable and Renewable Energy Engineering University of Sharjah27272 SharjahUnited Arab Emirates Mechanical Engineering Department Curtin University98009 MiriMalaysia College of Mechanical and Electrical Engineering Nanjing University of Aeronautics and AstronauticsNanjing 210016China Mechanical Engineering Department King Fahd University of Petroleum and MineralsDhahran 31261Saudi Arabia Department of Mechanical Engineering IK Gujral Punjab Technical UniversityKapurthala 144603PunjabIndia

The application of cutting fluid in the field of engineering manufacturing has a history of hundreds of years,and it plays a vital role in the processing efficiency and surface quality of *** them,water-based cutting fluid accounts for more than 90%of the consumption of cutting ***,long-term recycling of water-based cutting fluid could easily cause deterioration,and the breeding of bacteria could cause the cutting fluid to fail,increase manufacturing costs,and even endanger the health of *** bactericides could improve the biological stability of cutting fluids,but they are toxic to the environment and do not conform to the development trend of low-carbon ***-carbon manufacturing is inevitable and the direction of sustainable *** use of nanomaterials,transition metal complexes,and physical sterilization methods on the bacterial cell membrane and genetic material could effectively solve this *** this article,the mechanism of action of additives and microbial metabolites was first ***,the denaturation mechanism of traditional bactericides on the target protein and the effect of sterilization efficiency were ***,the mechanism of nanomaterials disrupting cell membrane potential was *** effects of lipophilicity and the atomic number of transition metal complexes on cell membrane penetration were also summarized,and the effects of ultraviolet rays and ozone on the destruction of bacterial genetic material were *** other words,the bactericidal performance,hazard,degradability,and economics of various sterilization methods were comprehensively evaluated,and the potential development direction of improving the biological stability of cutting fluid was proposed.

关键词： Cutting fluid Microorganism Bactericide Sterilization

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