检索结果-南通市图书馆

G protein-coupled receptor 37(GPR37) emerges as an important modulator of adenosinergic transmission in the striatum

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Neural Regeneration Research 2019年第11期14卷 1912-1914页

作者： Xavier Morato rodrigo A. Cunha Francisco Ciruela Unitat de Farmacologia Departament Patologia i Terapeutica ExperimentalFacultat de MedicinaInstituto de Investigacion Biomedica de Bellvitge (IDIBELL)Universitat de BarcelonaL’Hospitalet de LlobregatBarcelonaSpainInstitut de NeurocienciesUniversitat de BarcelonaBarcelonaSpain (Morato X Ciruela F) Center for Neuroscience and Cell Biology (CNC)-Center for Neurosciences and Cell BiologyUniversity of CoimbraCoimbraPortugalFaculty of MedicineUniversity of CoimbraCoimbraPortugal

G protein-coupled receptor 37 (GPR37), also known as parkin associated endothelin-like (Pael) receptor, is an orphan G protein- coupled receptor, which suffers a defective parking ubiquitination in autosomal recessive Parkinson’s disease promoting its endoplasmic reticulum aggregation and stress, neurotoxicity and neuronal death (Takahashi and Imai, 2003). Interestingly, we have demonstrated previously that GPR37 heteromerizes with adenosine A2A receptor (A2AR) in the striatum (Morato et al., 2017;Sokolina et al., 2017).

关键词： G protein-coupled receptor 37(GPR37) important modulator adenosinergic transmission

Local Fourier Analysis of multigrid Methods with Polynomial Smoothers and Aggressive Coarsening

在线全文

学校读者我要写书评

暂无评论

Numerical Mathematics(Theory,Methods and Applications) 2015年第1期8卷 1-21页

作者： James Brannick Xiaozhe Hu Carmen rodrigo Ludmil Zikatanov Department of Mathematics The Pennsylvania State UniversityUniversity ParkPA 16802USA Department of Mathematics Tufts University503 Boston Ave.MedfordMA 02155USA Department of Applied Mathematics University of ZaragozaC/Maria de Luna 350018ZaragozaSpain Institute of Mathematics and Informatics Bulgarian Academy of SciencesAcad.G.Bonchev Str.Bl.81113 SofiaBulgaria

We focus on the study of multigrid methods with aggressive coarsening and polynomial smoothers for the solution of the linear systems corresponding to finite difference/element discretizations of the Laplace *** local Fourier analysis we determine automatically the optimal values for the parameters involved in defining the polynomial smoothers and achieve fast convergence of cycles with aggressive *** also present numerical tests supporting the theoretical results and the heuristic *** methods we introduce are highly parallelizable and efficient multigrid algorithms on structured and semi-structured grids in two and three spatial dimensions.

关键词： multigrid local Fourier analysis polynomial smoothers aggressive coarsening

A Review on Cooperative Robotic Arms with Mobile or Drones Bases

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

International Journal of Automation and computing 2021年第4期18卷 536-555页

作者： Larona Pitso Ramalepa rodrigo S.Jamisola Jr. Botswana International University of Science and Technology Palapye 10071Botswana

This review paper focuses on cooperative robotic arms with mobile or drone bases performing cooperative tasks. This is because cooperative robots are often used as risk-reduction tools to human life. For example, they are used to explore dangerous places such as minefields and disarm explosives. Drones can be used to perform tasks such as aerial photography, military and defense missions,agricultural surveys, etc. The bases of the cooperative robotic arms can be stationary, mobile(ground), or drones. Cooperative manipulators allow faster performance of assigned tasks because of the available "extra hand". Furthermore, a mobile base increases the reachable ground workspace of cooperative manipulators while a drone base drastically increases this workspace to include the aerial *** papers in this review are chosen to extensively cover a wide variety of cooperative manipulation tasks and industries that use *** cooperative manipulation, avoiding self-collision is one of the most important tasks to be performed. In addition, path planning and formation control can be challenging because of the increased number of components to be coordinated.

关键词： Cooperative arms mobile manipulator aerial manipulator mobile base drone base cooperative tasks

Biosolid Application to Agricultural Land a Contribution to Global Phosphorus Recycle： A Review

在线全文

学校读者我要写书评

暂无评论

Pedosphere 2017年第1期27卷 1-16页

作者： Silvana Irene TORRI rodrigo Studart CORRt Giancarlo RENELLA Department of Natural Resources and Environment School of Agriculture University of Buenos Aires Avenue San Martin 4453 Buenos Aires 1417 DSE (Argentina) University of Brasilia-UnB/PPGCA Campus Darcy Ribeiro Caixa Postal 04401 70910-970 DF (Brazil) Department of Agrifood Production and Environmental Sciences University of Florence Piazzale delle Caseine 18 Florence 50144 (Italy)

Phosphorus(P) is an essential nutrient required for plant *** population growth and rising global demand for food are expected to increase the demand for phosphate ***,high-quality phosphate rock reserves are progressively becoming *** of the increased pressure on P resources could be alleviated by recycling P present in ***,it is crucial to understand the dynamics of P in biosolid-amended soils,the effects of residual biosolid-borne P in soils,the way in which microorganisms may control P dynamics in biosolid-amended soils and the environmental implications of the use of biosolids as a source of *** research is needed to maximize biosolid-borne P uptake by crops and minimize its loss from biosolid-amended *** analysis of the microbiological control of P dynamics in biosolid-amended soils indicates interactions of biosolid P with other nutrients such as carbon(C) and nitrogen(N),suggesting that harmonization of the current regulation on the use of biosolids in agriculture,mainly based on total N and pollutant contents,is needed to better recycle P in agriculture.

关键词： anthropogenic P phosphate P availability P biogeocycle P uptake runoff P

Quantum effects on dislocation motion from ring-polymer molecular dynamics

在线全文

学校读者我要写书评

暂无评论

npj Computational Materials 2018年第1期4卷 198-203页

作者： rodrigo Freitas Mark Asta Vasily V.Bulatov Department of Materials Science and Engineering University of CaliforniaBerkeleyCA 94720USA Lawrence Livermore National Laboratory LivermoreCA 94550USA Materials Sciences Division Lawrence Berkeley National LaboratoryBerkeleyCA 94720USA Department of Materials Science and Engineering Stanford UniversityStanfordCA 94305USA

Quantum motion of atoms known as zero-point vibration was recently proposed to explain a long-standing discrepancy between theoretically computed and experimentally measured low-temperature plastic strength of iron and possibly other metals with high atomic *** finding challenges the traditional notion that quantum motion of atoms is relatively unimportant in solids comprised of heavy *** we report quantum dynamic simulations of quantum effects on dislocation motion within the exact formalism of Ring-Polymer Molecular Dynamics(RPMD).To extend the reach of quantum atomistic simulations to length and time scales relevant for extended defects in materials,we implemented RPMD in the open-source code LAMMPS thus making the RPMD method widely available to the *** use our RPMD/LAMMPS approach for direct calculations of dislocation mobility and its effects on the yield strength ofα-*** simulation results establish that quantum effects are noticeable at temperatures below 50 K but account for only a modest(≈13% at T=0 K)overall reduction in the Peierls barrier,at variance with the factor of two reduction predicted earlier based on the more approximate framework of harmonic transition state *** results confirm that zero-point vibrations provide ample additional agitation for atomic motion that increases with decreasing temperature,however its enhancing effect on dislocation mobility is largely offset by an increase in the effective atom size,an effect known as quantum dispersion that has not been accounted for in the previous calculations.

关键词： theory quantum motion

Divergence in the ovipositional behavior of the Papilio glaucus group

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Insect Science 2008年第4期15卷 361-367页

作者： rodrigo J. Mercader J. Mark Scriber Department of Entomology Michigan State University East Lansing MI48824 USA

This study contrasts the ovipositional profiles of four members of the Papilio glaucus group, P. glaucus, P. multicaudatus, P. canadensis, and P. rutulus. We used seven choice oviposition bioassays containing leaves from hosts in seven plant families utilized by members of the P. glaucus group. Specifically, we contrast the overall ovipositional profiles of these species and their acceptance of a host in a novel plant family （Populus tremuloides： Salicaceae） and a host in a putatively ancestral host plant family （Liriodendron tulipifera： Magnoliaceae）. Significant differences were observed between the ovipositional profiles of P. glaucus and P. multicaudatus relative to each other and to P. canadensis and P. rutulus. In contrast, no significant differences were observed between the ovipositional profiles of P. canadensis and P. rutulus, which were also the only species that accepted P. tremuloides. Unlike the acceptance of P. tremuloides, the acceptance of L. tulipifera was present throughout the group despite the inability of the larvae of most species in the group to utilize this host. These results support the prediction of the ＂hierarchical threshold model＂ that ancestral host plants are likely to be retained in the ovipositional hierarchy while novel hosts should only be accepted by derived populations.

关键词： host preference insect-plant interactions Lepidoptera Papilionidae

Targeting resolvins in cholestatic liver injury

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Hepatobiliary Surgery and Nutrition 2021年第5期10卷 689-691页

作者： Luis AVidela rodrigo Valenzuela Molecular and Clinical Pharmacology Program Institute of Biomedical ScienceSantiagoChile Department of Nutrition Faculty of MedicineUniversity of ChileSantiagoChile

In general terms,the acute inflammatory reaction in conditions of infection or tissue damage is a response of the immune system to cope with survival and return to ***,the reaction is initiated by edema followed by the progressive accumulation of polymorphonuclear leukocytes(PMN)and monocytes that differentiate into macrophages,with production of pro-inflammatory mediators such as leukotrienes(e.g.,LTB4)and prostaglandins(e.g.,PGE2,PGI2,PGF2),which in excess may progress to chronic inflammation(1).Considering that the acute inflammatory response is a protective and self-limited phenomenon,its resolution is an active programmed reaction that is set in by specific pro-resolving mediators(SPMs),which are derived from n-3 polyunsaturated fatty acids(n-3 PUFAs).

关键词： protective acute homeostasis

Synthetic Time Series Generation Model for Analysis of Power System Operation and Expansion with High Renewable Energy Penetration

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Modern Power Systems and Clean Energy 2021年第4期9卷 849-858页

作者： rodrigo Palma-Behnke Jorge Vega-Herrera Felipe Valencia Oscar Nunez-Mata Energy Center Department of Electrical EngineeringFaculty of Mathematical and Physical SciencesUniversity of ChileSantiagoChile Department of Electrical Engineering University of AntofagastaAntofagastaChile School of Electrical Engineering University of Costa RicaSan PedroCosta Rica

The increasing integration of renewable energy sources into current power systems has posed the challenge of adequately representing the statistical properties associated with their variable power generation. In this paper, a novel procedure is proposed to select a proper synthetic time series generation model for renewable energy sources to analyze power system problems. The procedure takes advantage of the objective of the specific analysis to be performed and the statistical characteristics of the available time series. The aim is to determine the suitable model to be used for generating synthetic time series of renewable energy sources. A set of indicators is proposed to verify that the statistical properties of synthetic time series fit the statistical properties of the original data. The proposal can be integrated into systematic tools available for data analysis without compromising the representation of the statistical properties of the original time series. The procedure is tested using real data from the New Zealand power system in a mid-term analysis on integrating wind power plants into the power system. The results show that the proposed procedure reduces the error obtained in analyzing power systems compared with reference models.

关键词： Time series analysis renewable energy source solar energy stochastic process statistical analysis wind energy

Scrub typhus:pathophysiology,clinical manifestations and prognosis

在线全文

学校读者我要写书评

暂无评论

Asian Pacific Journal of Tropical Medicine 2012年第4期5卷 261-264页

作者： Senaka Rajapakse Chaturaka rodrigo Deepika Fernando Department of Clinical Medicine Faculty of Medicine25 Kynsey RoadColombo 8Sri Lanka Department of Parasitology Faculty of Medicine25 Kynsey RoadColombo 8Sri Lanka

Scrub typhus is a zoonosis caused by the pathogen Orientia tsutsugamushi(***). The disease has significant prevalence in eastern and Southeast *** presenting as an acute febrile illness,the diagnosis is often missed because of similarities with oilier tropical febrile *** unusual manifestations are present,and these are described in this review,together with an outline of current knowledge of *** of these unusual clinical manifestations will help the clinician to arrive at an early diagnosis,resulting in early administration of appropriate *** indicators for severe disease have not yet been clearly established.

关键词： Scrub typhus Orientia tsutsugamushi Clinical manifestations