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Total hip arthroplasty in patients with Paget's disease of bone: A systematic review

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World Journal of Orthopedics 2017年第4期8卷 357-363页

作者： Sammy A Hanna Sebastian Dawson-Bowling Steven Millington rej Bhumbra Pramod Achan Department of Trauma and Orthopaedic Surgery Royal London HospitalBarts Health NHS Trust

AiM To investigate the clinical and functional outcomes following total hip arthroplasty(THA) in patients with Paget's *** We carried out a systematic review of the literature to determine the functional outcome, complications and revision rates of THA in patients with Paget's disease. Eight studies involving 358 hips were reviewed. The mean age was 70.4 years and follow-up was 8.3 years. There were 247 cemented THAs(69%), 105 uncemented THAs(29%) and 6 hybrid THAs(2%). RESULTS All studies reported significant improvement in hip function following THA. There were 19 cases of aseptic loosening(5%) at a mean of 8.6 years. Three cases occurred in the uncemented cohort(3%) at a mean of 15.3 years and 16 cases developed in the cemented group(6%) at a mean of 7.5 years(P = 0.2052). There were 27 revisions in the 358 cases(8%) occurring at a mean of 7 years. Six revisions occurred in the uncemented cohort(6%) at a mean of 8.6 years and 21 in the cemented cohort(9%) at a mean of 6.5 years(P = 0.5117). CONCLUSiON The findings support the use of THA in patients with Paget's disease hip arthropathy. The post-operative functional outcome is largely similar to other patients; however, the revision rate is higher with aseptic loosening being the most common reason for revision. Uncemented implants appear to be associated with a lower failure rate, however, there were no modern stem designs fixed using current generation cementing techniques used in the reported studies, and as such, caution is advised when drawing any conclusions.

关键词： Total hip arthroplasty Paget’s disease Revision Loosening Heterotopic ossification

External and internal Quality Control:A Six Sigma Approach

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External and Internal Quality Control:A Six Sigma Approach

McAb生产的一种鉴定技术铟玻片免疫试验的应用

第三届全国临床检验实验室管理学术会议

作者： Robert rej Wadsworth Center for Laboratories and Research New York State Department of Health School of Public Health State University of New York at Albany Albany NY 12201-0509

来源： cnki会议评论

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单克隆抗体通讯 1990年第4期6卷 67-69页

作者： Robert rej 步恒富

常规技术生产McAb已得到广泛应用,其中筛选阳性克隆是最费时但又十分重要的步骤。各种酶联、荧光与放免等方法都在McAb筛选中得到相应的发展及应用,但这些方法无一不需要一种标记的抗原或抗体试剂。铟玻试验不需要标记试剂即可用于抗... 详细信息

常规技术生产McAb已得到广泛应用,其中筛选阳性克隆是最费时但又十分重要的步骤。各种酶联、荧光与放免等方法都在McAb筛选中得到相应的发展及应用,但这些方法无一不需要一种标记的抗原或抗体试剂。铟玻试验不需要标记试剂即可用于抗原抗体反应,并可用于McAb筛选。本文用微量ELiSA方法为对比,对铟玻试验有关因素进行了系统研究,结果表明,本法简便易行,敏感性与特异性高,结果判定迅速,是一种值得推广应用的筛选McAb技术。

关键词：单克隆抗体鉴定技术铟玻免疫试验

First Serological Evidence of Borna Disease Virus in Healthy Horses from Yucatan, Mexico

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Advances in Microbiology 2016年第7期6卷 489-494页

作者： Marco Torres-Castro Henry Noh-Pech Edwin Gutiérrez-Ruiz Julián García-rejón Carlos Machain-Williams Jorge Zavala-Castro Fernando i. Puerto Centro de investigaciones Regionales “Dr. Hideyo Noguchi” Universidad Autónoma de Yucatán Mérida México Campus de Ciencias Biológicas y Agropecuarias Universidad Autónoma de Yucatán Mérida México

Borna Disease Virus (BDV) causes a progressive non-suppurative meningoencephalitis that sometimes occurs in mortality;this disease has been reported for over two centuries ago in horses, sheep and cats in Central Europe and some regions of Asia. Currently, it is known that it causes neurological symptoms in various species of vertebrates including human beings. in Yucatan, Mexico, there is a single serological report about the circulation of BDV in schizophrenia patients;however, nothing is known about the circulation in animals. We obtained serum samples of 100 horses without apparent clinical signs caused by BDV infection, from various sites in the region. Antibodies against BDV were detected by electrochemiluminescence immunoassay (ECLiA) method with three recombinant proteins: BDV p24, BDV p40 and BDV p10 as antigens;obtaining a high seroprevalence of 44% (44/100). This study generates the first report of the probable activity of the BDV in healthy horses in Mexico and has expanded the infiltration area of BDV in the world. Nevertheless, several molecular investigations are required to detect BDV-RNA circulating and find sequences for clarification of the origin of BDV in Mexican horses.

关键词： Borna Disease Virus Electrochemiluminescence immunoassay Healthy Horses Yucatan Mexico

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等离子体源离子植入中的关键问题

国外核聚变与等离子体应用 1999年第3期 72-80页

作者： rej.,DJ 思虹

等离子体源离子植入（ＰＳＩＩ）是一项用于材料表面改性的可按比例增大的非视线方法，本文中，我们研究了在ＰＳＩＩ大规模商用应解决的三个重要问题，它们是：（１）植入保形性；（２）离子源和（３）级电子发射，为了确保复杂形状物... 详细信息

等离子体源离子植入（ＰＳＩＩ）是一项用于材料表面改性的可按比例增大的非视线方法，本文中，我们研究了在ＰＳＩＩ大规模商用应解决的三个重要问题，它们是：（１）植入保形性；（２）离子源和（３）级电子发射，为了确保复杂形状物体上的均匀的植入剂量，离子鞘层厚度必须足够小，这个标准对离子源和脉冲电源提出了要求，至今，另一个局限是除了Ｂ，Ｃ，Ｎ和Ｏ外其他类型离子的可用性。

关键词：等离子体源离子植入离子源胞中粒子计算

Determining the specific status of the iberian sturgeons by means genetic analyses of old specimens

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Advances in Bioscience and Biotechnology 2010年第3期1卷 171-179页

作者： Francisca Robles Belén Cano-Roldán Carmelo Ruiz rejón Luís Javier Martínez-González María Jesús álvarez-Cubero José Antonio Lorente José Antonio Riquelme Cantal Pedro Aguayo de Hoyos Javier Carrasco Rus Miguel Cortés Sánchez María Dolores Simón Vallejo Manuel Ruiz rejón Roberto de la Herrán 不详

To clarify the species status of sturgeon from rivers of the iberian Peninsula, eight molecular markers (4 nuclear and 4 mitochondrial) have been analysed in different specimens from historical museum samples and prehistoric samples from archaeological sites. These analyses indicate that one of these specimens (UGP captured in the Guadalquivir River in the 19th century) is A. sturio, based on all the eight molecular markers, four of them used from the first time in this study. in previous analyses based on 5 genetic markers, our group assigned two specimens captured in this river in the 1970-80s (EBD8173 and EBD8401) to the species A. naccarii, suggesting the presence of this species in the iberian Peninsula. in this work, this conclusion is drawn after successfully obtaining a mitochondrial marker in a very old scute from a prehistoric site (Acinipo, about 1500 BC, from the Guadalquivir River basin). On the other hand, in the specimen EBD8174 captured in the Guadalquivir in 1975, we have obtained two new mitochondrial markers confirming that it can be considered A. sturio for all the mitochondrial markers, but nuclear ones identify it as A. naccarii. Finally, two very old samples (Nerja E-Vi and Nerja N/62-63) were not successfully characterized by any molecular markers. Some aspects and consequences of our results are discussed, such as the origin of the “mosaic” specimen EBD8174 and, above all, the native status of A. naccarii in historic and prehistoric times in the southern iberian Peninsula.

关键词： iberian Sturgeons A. naccarii A. sturio Ancient DNA Genetic identification Molecular Markers.

Social correlates of sedentary behavior in young people:The UP&DOWN study

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Journal of Sport and Health Science 2020年第2期9卷 189-196页

作者： Veronica Cabanas-Sanchez Laura Garcia-Cervantes Laura Esteban-Gonzalo Maria Jose Girela-rejon Jose Castro-Pinero Oscar L.Veiga Department of Physical Education Sport and Human MovementAutonomous University of MadridMadrid 28049Spain Research Centre in Physical Activity Health and Leisure(CIAFEL)Faculty of SportUniversity of PortoPorto 4200-450Portugal Nursing Department Faculty of Biomedical and Health SciencesUniversidad Europea de MadridVillaviciosa de OdonMadrid 28670Spain Department of Didactic of Corporal Expression Faculty of Education SciencesUniversity of GranadaGranada 18010Spain Department of Physical Education School of EducationUniversity of CadizPuerto RealCadiz 11519Spain

Purpose:The aim of the present study was to analyze the associations of youths' sedentary behavior(SB) with parents' and siblings' SB and physical activity(PA),as well as the associations of youths' coparticipation with parents,siblings,and friends in PA and SB with youths' ***:The sample consisted of 1543 youths(12.02±2.51 years;788 boys) enrolled in the baseline cohort of the UP&DOWN *** was assessed by accelerometry and *** reported the time spent by their parents and siblings watching television,playing videogames,surfing the internet,sitting/resting,and doing ***,participants reported coparticipation with parents,siblings,and friends in these *** mixed models,including school and city as random effects,were ***:Parents' television time was positively associated with youths' screen-based *** with friends in playing videogames(in boys) and in surfing the internet(in girls) showed a positive association with screen-based SB and a negative association with educational-based ***,coparticipation with siblings and friends in PA was inversely associated with accelerometer-based SB in boys and ***:Our results emphasize the important role of social modeling in the development of sedentary lifestyles in *** aimed at reducing health risk behaviors in youths could be more effective if they are oriented from a social perspective that involves their families and networks of their closest friends.

关键词： Friends Parents Sedentary behavior Siblings Social environment

Physics prospects of the Jinping neutrino experiment

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Chinese Physics C 2017年第2期41卷 9-32页

作者： John *** 陈少敏程建平 Sayed N.Doustimotlagh 高原宁龚光华宫辉郭磊韩然何红建黄性涛李荐民李金李默涵李学潜廖玮林贵林刘佐伟 William Mc Donough Ondˇrej rmek 唐健万林焱王元清王喆王综轶魏瀚宇习宇飞徐晔许勋杰杨振伟姚春发 Minfang Yeh 岳骞张黎明张洋赵志宏郑阳恒周详朱相雷 Kai Zuber Dept. of Physics Dept. of Astronomy and CCAPP The Ohio State University Department of Engineering Physics Tsinghua University Science and Technology on Reliability and Environmental Engineering Laboratory Beijing Institute of Spacecraft Environment Engineering School of Physics Shandong University School of Physics Nankai University institute of Modern Physics East China University of Science and Technology institute of Physics National Chiao-Tung University University of Maryland College Park Department of Geophysics Faculty of Mathematics and Physics Charles University in Prague School of Physics Sun Yat-Sen University Department of Civil Engineering Tsinghua University institute of Hydrogeology and Environmental Geology Chinese Academy of Geological Sciences Fujian University of Technology Department of Structural Steels China Iron & Steel Research Institute Group Brookhaven National Laboratory School of Physical Sciences University of Chinese Academy of Sciences School of Physics and Technology Wuhan University institut für Kern- und Teilchenphysik Technische Universitt Dresden

The China Jinping Underground Laboratory（CJPL）, which has the lowest cosmic-ray muon flux and the lowest reactor neutrino flux of any laboratory, is ideal to carry out low-energy neutrino experiments. With two detectors and a total fiducial mass of 2000 tons for solar neutrino physics（equivalently, 3000 tons for geo-neutrino and supernova neutrino physics）, the Jinping neutrino experiment will have the potential to identify the neutrinos from the CNO fusion cycles of the Sun, to cover the transition phase for the solar neutrino oscillation from vacuum to matter mixing, and to measure the geo-neutrino flux, including the Th/U ratio. These goals can be fulfilled with mature existing techniques. Efforts on increasing the target mass with multi-modular neutrino detectors and on developing the slow liquid scintillator will increase the Jinping discovery potential in the study of solar neutrinos,geo-neutrinos, supernova neutrinos, and dark matter.

关键词： CJPL Jinping neutrino experiment solar neutrino geo-neutrino supernova neutrino

Performance and calibration of quark/gluon-jet taggers using 140 fb^(-1) of pp collisions at √s=13 TeV with the ATLAS detector

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Chinese Physics C 2024年第2期48卷 1-25页

作者： G. Aad B. Abbott K. Abeling N.J. Abicht S.H. Abidi A. Aboulhorma H. Abramowicz H. Abreu Y. Abulaiti B.S. Acharya C. Adam Bourdarios L. Adamczyk S.V. Addepalli M.J. Addison J. Adelman A. Adiguzel T. Adye A.A. Affolder Y. Afik M.N. Agaras J. Agarwala A. Aggarwal C. Agheorghiesei A. Ahmad F. Ahmadov W.S. Ahmed S. Ahuja X. Ai G. Aielli A. Aikot M. Ait Tamlihat B. Aitbenchikh i. Aizenberg M. Akbiyik T.P.A. Åkesson A.V. Akimov D. Akiyama N.N. Akolkar K. Al Khoury G.L. Alberghi J. Albert P. Albicocco G.L. Albouy S. Alderweireldt M. Aleksa i.N. Aleksandrov C. Alexa T. Alexopoulos F. Alfonsi M. Algren M. Alhroob B. Ali H.M.J. Ali S. Ali S.W. Alibocus M. Aliev G. Alimonti W. Alkakhi C. Allaire B.M.M. Allbrooke J.F. Allen C.A. Allendes Flores P.P. Allport A. Aloisio F. Alonso C. Alpigiani M. Alvarez Estevez A. Alvarez Fernandez M. Alves Cardoso M.G. Alviggi M. Aly Y. Amaral Coutinho A. Ambler C. Amelung M. Amerl C.G. Ames D. Amidei S.P. Amor Dos Santos K.R. Amos V. Ananiev C. Anastopoulos T. Andeen J.K. Anders S.Y. Andrean A. Andreazza S. Angelidakis A. Angerami A.V. Anisenkov A. Annovi C. Antel M.T. Anthony E. Antipov M. Antonelli F. Anulli M. Aoki T. Aoki J.A. Aparisi Pozo M.A. Aparo L. Aperio Bella C. Appelt A. Apyan N. Aranzabal S.J. Arbiol Val C. Arcangeletti A.T.H. Arce E. Arena J-F. Arguin S. Argyropoulos J.-H. Arling O. Arnaez H. Arnold G. Artoni H. Asada K. Asai S. Asai N.A. Asbah J. Assahsah K. Assamagan R. Astalos S. Atashi R.J. Atkin M. Atkinson H. Atmani P.A. Atmasiddha K. Augsten S. Auricchio A.D. Auriol V.A. Austrup G. Avolio K. Axiotis G. Azuelos D. Babal H. Bachacou K. Bachas A. Bachiu F. Backman A. Badea P. Bagnaia M. Bahmani A.J. Bailey V.R. Bailey J.T. Baines L. Baines O.K. Baker E. Bakos D. Bakshi Gupta V. Balakrishnan R. Balasubramanian E.M. Baldin P. Balek E. Ballabene F. Balli L.M. Baltes W.K. Balunas J. Balz E. Banas M. Bandieramonte A. Bandyopadhyay S. Bansal L. Barak M. Barakat E.L. Barberio D. Barberis M. Barbero M.Z. Barel K.N. Barends T. Barillari M-S. Barisits T. Barklow P. Baron D.A. Baron Mo The ATLAS Collaboration

The identification of jets originating from quarks and gluons,often referred to as quark/gluon tagging,plays an important role in various analyses performed at the Large Hadron Collider,as Standard Model measurements and searches for new particles decaying to quarks often rely on suppressing a large gluon-induced *** paper describes the measurement of the efficiencies of quark/gluon taggers developed within the ATLAS Collaboration,using √s=13 TeV proton–proton collision data with an integrated luminosity of 140 fb^(-1) collected by the ATLAS *** taggers with high performances in rejecting jets from gluon over jets from quarks are studied:one tagger is based on requirements on the number of inner-detector tracks associated with the jet,and the other combines several jet substructure observables using a boosted decision tree.A method is established to determine the quark/gluon fraction in data,by using quark/gluon-enriched subsamples defined by the jet *** in tagging efficiency between data and simulation are provided for jets with transverse momentum between 500 GeV and 2 TeV and for multiple tagger working points.

关键词： ATLAS JET QUARK GLUON TAGGiNG