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Lipomatous ependymoma with ZFTA:RELA fusion-positive:A case report

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World Journal of Clinical Cases 2025年第1期13卷 48-55页

作者： Xiao-Yu Zhao Juan-Han Yu Yi-Hua Wang Yi-xin Liu Lu Xu Lin Fu Ning Yi China Medical University The First Hospital of China Medical UniversityShenyang 110001Liaoning ProvinceChina Department of Pathology The First Hospital of China Medical UniversityShenyang 110001Liaoning ProvinceChina Anshan Cancer Hospital Anshan 114000Liaoning ProvinceChina

BACKGROUND Ependymoma with lipomatous differentiation is a rare type of *** ZFTA fusion-positive supratentorial ependymoma is a novel tumor type in the 2021 World Health Organization classification of central nervous system *** fusion-positive lipomatous ependymoma has not been reported to *** SUMMARY We reported a case of a 15-year-old Chinese male who had a sudden convulsion lasting approximately six *** resonance imaging showed a round cystic shadow of approximately 1.9 cm×1.5 cm×1.9 cm under the right parieto-occipital *** examination showed characteristic perivascular pseudorosettes and adipose differentiation in the ***-chemical staining showed that the tumor cells were negative for cytokeratin,NeuN,Syn and p53,but positive for GFAP,vimentin and S-100 ***-ficant punctate intracytoplasmic EMA immunoreactivity was *** level of Ki-67 was about 5%.Genetic analysis revealed ZFTA:RELA fusion.A cranio-tomy with total excision of the tumor was *** follow-up time was 36 months,no evidence of disease recurrence was found in magnetic resonance *** Based on these findings,the patient was diagnosed as a ependymoma with ZFTA fusion and lipomatous *** case report provides information on the microscopic morphological features of ependymoma with ZFTA fusion and lipomatous differentiation,which can help pathologists to make a definitive diagnosis of this tumor.

关键词： Ependymoma Lipomatous Molecular classification Supratentorial ZFTA:RELA fusion Case report

Effect of pH on biologic degradation of Microcystis aeruginosa by alga-lysing bacteria in sequencing batch biofilm reactors

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Frontiers of Environmental Science & Engineering 2012年第2期6卷 224-230页

作者： Hongjing LI mengli HAO Jingxian LIU Chen CHEN Zhengqiu FAN Xiangrong WANG Department of Environmental Science and Engineering Fudan UniversityShanghai 200433China

In this paper, the effect of pH on biological degradation of Microcystis aeruginosa by alga-lysing bacteria in laboratory-scale sequencing batch biofilm reactors （SBBRs） was investigated. After 10 d filming with waste activated sludge, the biological film could be formed, and the bioreactors in which laid polyolefin resin filler were used to treat algal culture. By comparing the removal efficiency of chlorophyll a at different aerobic time, the optimum time was determined as 5 h. Under pH 6.5, 7.5, and 8.5 conditions, the removal rates of Microcystis aeruginosa were respectively 75.9%, 83.6%, and 78.3% （in term of chlorophyll a）, and that of Chemical Oxygen Demand （CODMn） were 30.6%, 35.8%, and 33.5%. While the removal efficiencies of ammonia nitrogen （NH＋ -N） were all 100%. It was observed that the sequence of the removal efficiencies of algae, NH＋ -N and organic matter were pH 7.5 〉 pH 8.5 〉 pH 6.5. The results showed that the dominant alga-lysing bacteria in the SBBRs was strain HM-01, which was identified as Bacillus sp. by Polymerase Chain Reaction （PCR） amplification of the 16S rRNA gene, Basic Local Alignment Search Tool （BLAST） analysis, and compar- ison with sequences in the GenBank nucleotide database. The algicidal activated substance which HM-01 strain excreted could withstand high temperature and pressure, also had better hydrophily and stronger polarity.

关键词： pH biological degradation alga-lysing bac-teria sequencing batch biofilm reactor (SBBR) 16S rRNA,Bacillus sp

Antifungal Activity of Schinifoline Against Candida Albicans in Caenorhabditis Elegans

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Phyton-International Journal of Experimental Botany 2019年第3期88卷 317-324页

作者： Chengjie Shu mengli Zhang Weiming Zhang Shihong Ma Guoqing Chen Baojun Shi Nanjing Institute for Comprehensive Utilization of Wild Plants Nanjing211100China Dongping Jiuxin Biochemical Co. Ltd.Taian271506China

Zanthoxylum schinifolium has been used as spices and traditional medicine in China for hundreds of years.A variety of active substances have been isolated from Zanthoxylum schinifolium using biological and chemical *** these substances,the effect of schinifoline has gradually attracted much *** albicans is one of the most common pathogens isolated from the gastrointestinal tract,vagina,and mouth in healthy *** a healthy population,there are various mechanisms in host,such as the microbial flora,the epithelial barriers,and the innate immune system,that can control the presence of Candida ***,when host immunity is compromised,an invasive fungal infection is more likely to *** this study,we explored the antifungal activity of schinifoline against Candida albicans in Caenorhabditis *** determine the optimal concentration of schinifoline,we investigated the lifespan,defecation cycle and locomotion behavior of Caenorhabditis elegans after treatment with *** addition,we examined colony formation in the intestine of Caenorhabditis elegans after Candida albicans *** results indicated that 100 and 200 mg/L of schinifoline could prolonged the lifespan,shorten the defecation cycle and increased the locomotion behavior of Caenorhabditis elegans,with 100 mg/L of schinifoline being the optimal ***,100 mg/L of schinifoline increased the lifespan of Caenorhabditis elegans after infection and inhibited the colony formation of Candida albicans in Caenorhabditis elegans ***,we concluded that schinifoline exhibits anti-fungal effects and its potential use as natural drugs should be further explored in future studies.

关键词： Schinifoline fungistasis anti-aging Candida albicans Caenorhabditis elegans

Health analytics in business research:a literature review

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Journal of Management Analytics 2023年第3期10卷 447-476页

作者： Quanchen Liu mengli Yu Bingqing Xiong Zhao Cai Pengzhu Zhang Chee-Wee Tan Antai College of Economics&Management Shanghai Jiao Tong UniversityShanghaiPeople’s Republic of China Department of Digitalization Copenhagen Business SchoolFrederiksbergDenmark School of Journalism and Communication Nankai UniversityTianjinPeople’s Republic of China Convergence Media Research Center Nankai UniversityTianjinPeople’s Republic of China Deakin Business School Deakin UniversityBurwoodVICAustralia fNottingham University Business School China University of Nottingham Ningbo ChinaNingboChina

Technological advances have enabled the collection of large quantities of valuable data for health-related ***,a growing number of scholars are paying attention to the application of health analytics to business topics.A comprehensive analysis of health analytics application in business research is necessary to realize the commercial value of health *** this article,we summarize peer-reviewed articles that have been published in business journals,with an eye toward formulating a roadmap for applying health analytics across multiple business ***,we demonstrate how health-related data can be harnessed to inform business ***,we endeavor to consolidate the available datasets and analytical techniques commonly employed to explore health analytics in business ***,we discuss the practical challenges confronting scholars in health analytics,as well as future research *** from our study yields insights that can be leveraged by business scholars interested in health analytics research.

关键词： health analytics business topics literature review managerial challenges big data

Distributed Sequential Adaptive Weighted Localization of a Gas-Leakage Source Using a Wireless Sensor Network

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Distributed Sequential Adaptive Weighted Localization of a G...

基于乳脂肪球膜结构以提高液态乳体系的稳定性:乳脂肪球膜构建机制综述

第25届中国控制与决策会议

作者： mengli Cao Qinghao Meng Yuxiu Wu Ming Zeng Institute ofRobotics and Autonomous Systems Tianjin University

ISBN: (纸本)9781467355339

We propose an effective algorithm to localize a continuous gas-leakage source using a wireless sensor network （WSN）. We first derive the possible source locations by reverse derivation from the diffusion model using Lambert W function, and then the most possible source location is determined based on prior information. Finally, the most-possible source location is incorporated into the localization result, which is updated in a distributed sequential manner by adaptive weighted summation. Our algorithm is shown to achieve excellent performance, even in the case that the actual source is far away from the sensor-deployment area. The computational complexity is applicable for WSNs with relatively low calculating ability.

关键词： In-network signal processing Collaborative source localization Distributed sequential processing Wireless sensor network Gas leak detection.

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食品科学 2025年第2期46卷 308-316页

作者：王鑫于景华赵亭亭刘晓辉天津科技大学食品科学与工程学院食品营养与安全国家重点实验室天津300457 河北省功能油脂微胶囊化技术创新中心河北石家庄052160

乳脂肪球起源于乳腺上皮细胞,脂肪球膜中的脂质和蛋白质通过静电斥力和空间位阻维持脂肪球的稳定性,同时膜上的成分具有特定的营养特性。脂肪球界面的重新构建对液态乳制品的品质至关重要,本文对近年来加工中乳脂肪球界面构建机制的研... 详细信息

乳脂肪球起源于乳腺上皮细胞,脂肪球膜中的脂质和蛋白质通过静电斥力和空间位阻维持脂肪球的稳定性,同时膜上的成分具有特定的营养特性。脂肪球界面的重新构建对液态乳制品的品质至关重要,本文对近年来加工中乳脂肪球界面构建机制的研究进行总结并发掘共通之处。均质会破坏脂肪球膜的原生结构,导致膜结构重新排列。此外,热处理也会改变蛋白质的结构,并引起脂质结构域的侧向分离。同时,脂肪球膜上蛋白质和脂质的热响应会导致原始膜成分的损失。外源添加物通过改善油水界面和增强脂肪球的稳定性,参与体系稳定化的重构建。未来需深入研究脂肪球膜构建机制与宏观体系的联系,并优化特定的加工条件,以获得更高品质的乳制品。

关键词：脂肪球脂肪球膜脂肪球膜蛋白脂质域重构建

Dielectric and thermal properties characterisation and evaluation of novel epoxy materials for high-voltage power module packaging

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High Voltage 2024年第5期9卷 1021-1032页

作者： Zhengdong Wang Ganqiu Yang Xiaolong Cao mengli Li Tong Zhang Chenxin Liu Yuanhang Zhou Yonghong Cheng School of Mechanical and Electrical Engineering Xi'an University of Architecture and TechnologyXi'anChina State Key Laboratory of Electrical Insulation and Power Equipment Xi'an Jiaotong UniversityXi'anChina

Internal insulation of high-voltage power modules is facing interesting failure risks,including high temperature overheating,breakdown fault,material cracking etc.,so it is imperative to urgently develop new dielectric materials with high thermal conductivity(λ),outstanding electrical insulation,and thermal stability properties.A method to construct controllable liquid crystalline cross-linking networks based on the synthesis of biphenyl epoxy monomer and the change of curing agent structures and curing temperature is *** uniform nematic rod-like liquid crystalline domains were obtained by using 4,4-diaminodiphenylmethane as a curing agent under a pre-curing temperature of 105°*** resulting film(abbreviated as TD-105)exhibitedλup to 0.53 W m^(-1) K^(-1) and a dielectric breakdown strength of 57.69 kV mm^(-1),which showed a simultaneous enhancement of 178%and 16%,respectively,compared to traditional bisphenol A epoxy ***,it also exhibited lower dielectric loss and magnitude of partial discharge while having higher glass-transition temperature(190°C).A novel idea for the development of high-performance epoxy insulating materials for the application of high-voltage and large-power electrical equipment is provided.

关键词： thermal dielectric curing

Preparation of Gallic Acid-chitosan Copolymer and Its Antibacterial Activity against Staphylococcus Aureus and Escherichia Coli

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Journal of Wuhan University of Technology(Materials Science) 2021年第6期36卷 934-941页

作者： YAN Chunchao XIAO Feng QIU Tong ZHANG Xueqiong ZHAN Siwen LU mengli YANG Mengjia ZHANG Juan College of Pharmacy Hubei University of Chinese MedicineWuhan 430065China Department of Pharmacy Hubei Provincial Hospital of Traditional Chinese MedicineWuhan 430060China School of Chemistry Chemical Engineering and Life SciencesWuhan University of TechnologyWuhan 430070China Maternal and Child Health Hospital of Hubei Wuhan 430070China

To synthesize three different grafting ratios of gallic acid(GA)-chitosan(CS)copolymer by a free radical mediated grafting method,which is further applied to the field of antibacterial materials,crosslinking structures of the compound GA-CS copolymer were characterized,fully indicating that gallic acid is resoundingly grafted onto *** grafting ratios of three copolymers GA-CS are 45.71%(Ⅰ),36.12%(Ⅱ),and 18.96%(Ⅲ)were determined by UV-Vis *** minimum inhibitory concentrations of three GA-CS copolymers are 30μg/mL against Escherichia coli and are ranged from 250 to 550μg/mL against Staphylococcus *** counting viable bacterial colonies,it can be found that antibacterial property is preferable by increasing the grafting ratio of GA-CS *** of investigation on aforementioned bacteria experiment indicate that the CFU/mL values of GA-CS(Ⅰ,Ⅱ,Ⅲ)are 2.04×10^(6),7.56×10^(6),1.48×10^(7) to Staphylococcus aureus,and 2.96×10^(6),1.01×10^(7),2.14×10^(7) to Escherichia coli after 12 h *** addition,the interaction process between GA-CS copolymer and bacteria can be observed through a transmission electron *** specific manifestation is that the bacterial cell membranes are ruptured after being treated with the copolymer,which causes the cell contents to flow out,and the cell morphology is shrunk and out ofshape.

关键词： gallic acid chitosan antibacterial activity antibacterial material

Gut-brain axis as a bridge in obesity and depression:Mechanistic exploration and therapeutic prospects

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World Journal of Psychiatry 2025年第1期15卷 12-20页

作者： Rui-Ying Fang Xiao-Rui Pan xin-xing Zeng Zheng-Zheng Li Bo-Fan Chen Hai-Min Zeng Jie Peng The Second Clinical Medical College The Second Affiliated HospitalJiangxi Medical CollegeNanchang UniversityNanchang 330006Jiangxi ProvinceChina

A recent study by Wang et al,published in the World Journal of Psychiatry,provided preventative and therapeutic strategies for the comorbidity of obesity and *** gut-brain axis,which acts as a two-way communication system between the gastrointestinal tract and the central nervous system,plays a pivotal role in the pathogenesis of these *** suggests that metabolic byproducts,such as short-chain fatty acids,lipopolysaccharide and bile acids,which are generated by the gut microbiota,along with neurotransmitters and inflammatory mediators within the gut-brain axis,modulate the host's metabolic processes,neuronal regulation,and immune responses through diverse *** interaction between obesity and depression via the gut-brain axis involves disruptions in the gut microbiota balance,inflammatory immune responses,and alterations in the neuroendocrine *** the gut-brain axis,for example,through a ketogenic diet,the use of probiotics,and the supplementation of antioxidants,offers new remedial approaches for obesity and *** research that explores the mechanisms of the gut-brain axis is needed to provide more evidence for clinical treatment.

关键词： Gut-brain axis Obesity Depression Gut microbiota Mechanism