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Science China Life Sciences 2025年

作者： Yanlong Li Yinuo Fu Yaoyao Li Rui Zhang jing Yang Huanhuan ma Ling Min Xianlong Zhang National Key Laboratory of Crop Genetic Improvement Huazhong Agricultural University

High temperature (HT) stress causes male sterility,leading to reduced upland cotton ***,we identified a key gene,Casein Kinase I (GhCKI),that negatively regulates male fertility in upland cotton under ***,conventional genetic manipulations of GhCKI would result in male sterility,hindering its utilization in breeding ***,we engineered quantitative variation for anther thermotolerance-related traits in upland cotton by creating weak promoter alleles of GhCKI genes,using CRISPR/Cas9 and CRISPR/Cpf1genome ***,we screened and identified two new upland cotton plant lines exhibiting a HT-tolerant phenotype with edited GhCKI promoters,and characterized their corresponding heat-tolerant allelic *** research revealed that the primary reason for the HT tolerance of the GhCKI promoter editing mutants is that the trans-acting factors GhMYB73 and GhMYB4,which positively regulate GhCKI expression under HT,failed to bind and activate the expression of ***,our study not only provides a rapid strategy to generate new beneficial alleles but also offers novel germplasm resources and molecular insights for crop HT tolerance breeding.

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Effects of Lignite Humic Acid and Lignite Humic Acid-based Combined Amendment on Soil Quality in Saline-sodic Farmlands in the West Liaohe Plain, China

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Chinese Geographical Science 2025年第2期 401-414页

作者： NIE Zhaoyang ZHANG Lu ZHANG Tieyi GUO Liangliang ZHOU jie AN Fenghua ma Hongyuan WANG Zhichun YANG Fan Northeast Institute of Geography and Agroecology Chinese Academy of Sciences University of Chinese Academy of Sciences Jilin Agricultural University

Water scarcity and soil salinization pose significant challenges to agriculture in the West Liaohe Plain, eastern Inner Mongolia, China. Shallow-buried drip irrigation can improve soil water use efficiency to alleviate water shortage in agriculture and the application of lignite humic acid reduces the adverse effects of soil salinization. However, further research is needed to investigate the effects of different application rates of lignite humic acid and humic acid-based combined amendment on soil physicochemical properties, nutrient contents, and crop yield in saline-sodic farmlands under shallow-buried drip irrigation. A two-year field experiment was conducted with control without any amendment(CK), three treatments amended with 3 t/ha(H1), 6 t/ha(H2), and 12 t/ha(H3) lignite humic acid,and three application rates with 15 t/ha(T1), 22.5 t/ha(T2), and 30 t/ha(T3) lignite humic acid-based combined amendment in 2021 and2022. The results showed that H3 reduced soil bulk density, p H, electrical conductivity, and total alkalinity, while increasing the contents of soil organic matter, total nitrogen, and available potassium in the two-year experiment. Moreover, the maize yield in H3 increased by an average of 35.5%. T2 decreased soil bulk density, p H, total alkalinity, and increased maize yield by 16.2%, compared to the first year. These results suggest that T2 consistently improved both soil quality and crop yield. Correlation analyses showed that lignite humic acid and its complexes promote maize growth and increase yield by increasing soil organic matter and total nitrogen while reducing soil salinity and total alkalinity. Based on the comprehensive analysis of the field data and the results of the comprehensive evaluation of soil quality, it was determined that the appropriate improvement measures for saline-sodic farmlands under shallow-buried drip irrigation are the application of 12 t/ha of lignite humic acid and 22.5 t/ha of lignite humic acid-based combined

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Locally Enhanced Flow and Electric Fields Through a Tip Effect for Efficient Flow‑Electrode Capacitive Deionization

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Nano-Micro Letters 2025年第2期17卷 1-17页

作者： Ziquan Wang Xiangfeng Chen Yuan Zhang jie ma Zhiqun Lin Amor Abdelkader maria‑magdalena Titirici Libo Deng College of Chemistry and Environmental Engineering Shenzhen UniversityShenzhen 518060People’s Republic of China Research Center for Environmental Functional materials College of Environmental Science and EngineeringTongji University1239 Siping RoadShanghai 200092People’s Republic of China Department of Chemical and Biomolecular Engineering National University of SingaporeSingapore 117585Singapore Department of Engineering Faculty of Science and TechnologyBournemouth UniversityTalbot CampusFern BarrowPooleEngland BH125BBUK Institut de Chimie de Nice UniversitéCôte d’AzurUMR CNRS 727228 Av.Valrose06108 NiceFrance Department of Chemical Engineering Imperial College LondonSouth Kensington CampusExhibition RdLondon SW72AZUK

Low-electrode capacitive deionization(FCDI)is an emerging desalination technology with great potential for removal and/or recycling ions from a range of ***,it still suffers from inefficient charge transfer and ion transport kinetics due to weak turbulence and low electric intensity in flow electrodes,both restricted by the current ***,a new tip-array current collector(designated as T-CC)was developed to replace the conventional planar current collectors,which intensifies both the charge transfer and ion transport *** effects of tip arrays on flow and electric fields were studied by both computational simulations and electrochemical impedance spectroscopy,which revealed the reduction of ion transport barrier,charge transport barrier and internal *** the voltage increased from 1.0 to 1.5 and 2.0 V,the T-CC-based FCDI system(T-FCDI)exhibited average salt removal rates(ASRR)of 0.18,0.50,and 0.89μmol cm^(-2) min^(-1),respectively,which are 1.82,2.65,and 2.48 folds higher than that of the conventional serpentine current collectors,and 1.48,1.67,and 1.49 folds higher than that of the planar current ***,with the solid content in flow electrodes increased from 1 to 5 wt%,the ASRR for T-FCDI increased from 0.29 to 0.50μmol cm^(-2) min^(-1),which are 1.70 and 1.67 folds higher than that of the planar current ***,a salt removal efficiency of 99.89%was achieved with T-FCDI and the charge efficiency remained above 95%after 24 h of operation,thus showing its superior long-term stability.

关键词： Flow-electrode Capacitive deionization Current collector Tip effect Desalination

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水产养殖废水污染物含量与农灌适用性分析

长江流域资源与环境 2023年第10期32卷 2173-2183页

作者：郑天铭王沛芳胡斌张明马晶洁王洵李鼎新河海大学环境学院江苏南京210098 河海大学浅水湖泊综合治理与资源开发教育部重点实验室江苏南京210098 江苏省泰州引江河管理处江苏泰州225321

为助力长江大保护,实现循环农业的可持续发展,针对水产养殖废水回用的安全问题,于2022年3月监测了长江江苏段典型养殖模式下虾蟹塘和鱼类塘废水中的重金属、农药和抗生素含量,并借助内梅罗综合指数法和生态风险指数法评估其回用于农田... 详细信息

为助力长江大保护,实现循环农业的可持续发展,针对水产养殖废水回用的安全问题,于2022年3月监测了长江江苏段典型养殖模式下虾蟹塘和鱼类塘废水中的重金属、农药和抗生素含量,并借助内梅罗综合指数法和生态风险指数法评估其回用于农田灌溉的可行性。结果表明:重金属中Zn含量最高,虾蟹塘和鱼类塘废水含量分别为19.40和15.39μg·L^(-1),其次为As、Ni、Pb;农药中扑草净含量最高,可达149.28 ng·L^(-1),除草剂和杀菌剂为养殖废水的主要农药种类;抗生素中氟苯尼考含量最高,可达151.40 ng·L^(-1),大环内酯类和酰氨醇类分别为虾蟹塘和鱼类塘废水的主要抗生素种类。风险评估表明,重金属平均含量低于《农田灌溉水质标准(GB5084-2021)》限值,仅S1的Hg具有潜在风险,使得该虾蟹塘废水表现为轻度污染;鱼类塘废水中农药和抗生素均对浮游植物产生高风险,RQ平均为4.11和36.94,而虾蟹塘废水中仅农药呈现高风险,其RQ为2.72。虾蟹塘中Hg和异丙甲草胺,鱼类塘中异丙甲草胺、多菌灵、氟苯尼考和磺胺甲噁唑为潜在的风险源,但各污染物含量均低于农作物的效应浓度。因此,养殖废水可用于农田灌溉,长期应用时需要进行针对性监测和处理。

关键词：水产养殖废水重金属农药抗生素农灌适用性

安内与攘外——代际传承对家族企业社会责任履行的影响

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山西财经大学学报 2025年第1期47卷 86-97页

作者：黄杰郑静南京大学政府管理学院江苏南京210023 清华大学社会科学学院北京100084

基于全国私营企业调查数据,检验代际传承对企业社会责任履行的影响。研究发现:在传承期,企业的内外合法性需求促使企业履行内外社会责任;中小规模企业的代际传承面临内部合法性挑战,需要通过“安内”团结员工;大规模企业需要解决外部合... 详细信息

基于全国私营企业调查数据,检验代际传承对企业社会责任履行的影响。研究发现:在传承期,企业的内外合法性需求促使企业履行内外社会责任;中小规模企业的代际传承面临内部合法性挑战,需要通过“安内”团结员工;大规模企业需要解决外部合法性问题,“攘外”成为优先选择。研究结论丰富了家族企业社会责任内涵,为引导家族企业承担社会责任提供了有益启示。

关键词：家族企业代际传承合法性内部社会责任外部社会责任企业规模政治联系市场环境

Alpiniae oxyphyllae Fructus ameliorates renal lipid accumulation in diabetic kidney disease via activating PPARα

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Asian Pacific Journal of Tropical Biomedicine 2025年第1期15卷 11-23,I0008-I0012页

作者： Zi-jie Yan Lin Zhang Xin-Yao Han Yu Kang Shu-man Liu Tian-Peng ma man Xiao Yi-Qiang Xie College of Traditional Chinese Medicine Hainan Medical UniversityHaikou 571199China First Clinical College of Medicine of Guizhou University of Traditional Chinese Medicine Guiyang 550002China Heilongjiang Academy of Traditional Chinese Medicine Harbin 150001China Key Laboratory of Tropical Translational Medicine of Ministry of Education School of Basic Medicine and Life SciencesHainan Medical UniversityHaikou 571199China

Objective:To investigate the effects of Alpiniae oxyphyllae Fructus(AOF)on renal lipid deposition in diabetic kidney disease(DKD)and elucidate its molecular ***:The mechanism of AOF in treating DKD was explored by network pharmacological enrichment analysis,molecular docking,and molecular dynamics *** effects of AOF on renal function and lipid deposition were assessed in a mouse model of DKD and high glucose-stressed HK-2 *** viability and lipid accumulation were detected by CCK8 and oil red O *** expressions of PPARαand fatty acid oxidation-related genes(ACOX1 and CPT1A)were detected by quantitative RT-PCR,Western blot,and ***,PPARαknockdown was performed to examine the molecular mechanism of AOF in treating ***:Network pharmacological enrichment analysis,molecular docking,and molecular dynamics simulation showed that the active compounds in AOF targeted PPARαand thus transcriptionally regulated ACOX1 and *** lowered blood glucose,improved dyslipidemia,and attenuated renal injury in DKD ***-containing serum accentuated high glucose-induced decrease in cell viability and ameliorated lipid ***,it significantly upregulated the expression of PPARα,ACOX1,and CPT1A in both in vivo and in vitro experiments,which was reversed by PPARα***:AOF may promote fatty acid oxidation via PPARαto ameliorate renal lipid deposition in DKD.

关键词： Diabetic kidney disease Alpiniae oxyphyllae Fructus Natural medicine Lipid accumulation PPARα Fatty acid oxidation

HPLC-MS/MS法同时测定肝微粒体孵育体系中地西泮及其代谢产物的浓度

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中国临床药理学杂志 2015年第12期31卷 1180-1183页

作者：徐亚飞董瑞华曲恒燕王静刘泽源马静洁军事医学科学院附属医院临床药理学研究室延边大学药学院

目的建立同时测定地西泮及其代谢产物质量浓度的HPLC-MS/MS方法。方法色谱柱:Kromasil C18,流动相:乙腈-2 mmol·L-1乙酸铵水溶液（70∶30）,流速:0.3 m L·min-1,柱温:40℃,用正离子扫描,多反应监测方式测定样品中药物的质量浓度。考... 详细信息

目的建立同时测定地西泮及其代谢产物质量浓度的HPLC-MS/MS方法。方法色谱柱:Kromasil C18,流动相:乙腈-2 mmol·L-1乙酸铵水溶液（70∶30）,流速:0.3 m L·min-1,柱温:40℃,用正离子扫描,多反应监测方式测定样品中药物的质量浓度。考察该方法的专属性、标准曲线和定量下限、精密度与回收率、基质效应及稳定性。结果肝微粒体孵育样品中,地西泮在20;000ng·m L-1线性关系良好（r>0.99）,定量下限为20 ng·m L-1。去甲地西泮、替马西泮和奥沙西泮在2;00 ng·m L-1线性关系良好（r>0.99）,定量下限为2ng·m L-1。地西泮、去甲地西泮、替马西泮和奥沙西泮绝度回收率分别在55.47%;8.76%,64.84%;9.11%,68.32%;8.27%和72.66%;3.82%,日内与日间精密度均小于15%。结论本研究方法简便、快速、准确,适用于测定肝微粒体孵育样品中地西泮及其代谢产物的浓度。

关键词：高效液相色谱-质谱联用法地西泮去甲地西泮替马西泮奥沙西泮

Semiconductor clusters enable high-efficiency extraction of hot electrons from gold nanorods for photocatalytic organic conversions

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Science China Chemistry 2025年

作者： Jia-Xing Liu Hao ma Shang-Fu Yuan jing-Ni Zhang jing-Guan Liang Rui Zhou Dong-Sheng Li Wen-Bin Chen Ming-De Li Tao Wu State Key Laboratory of Bioactive Molecules and Druggability Assessment Guangdong Basic Research Center of Excellence for Natural Bioactive Molecules and Discovery of Innovative Drugs College of Chemistry and Materials Science Guangdong Provincial Key Laboratory of Supramolecular Coordination Chemistry Jinan University Department of Developmental and Regenerative Biology Jinan University College of materials and Chemical Engineering Hubei Provincial Collaborative Innovation Center for New Energy Microgrid Key Laboratory of Inorganic Nonmetallic Crystalline and Energy Conversion Materials China Three Gorges University College of Chemistry and Chemical Engineering Key Laboratory for Preparation and Application of Ordered Structural Materials of Guangdong Province Shantou University

Plasmon-induced hot energy in metal nanostructures holds great promise for photocatalytic organic conversions. However,maintaining the high-energy state of hot electrons within these structures remains challenging, even in hybrid metal-semiconductor heterojunctions. The rapid relaxation of hot electrons（mall metal chalcogenide semiconductor clusters（P2） with gold nanorods（AuNRs）, which exhibits high-efficiency extraction of hot electrons and photocatalytic application. The robust binding of P2 cluster, with its smaller volume and larger energy level splitting compared to large-sized quantum dots, not only significantly increases the yield of hot electrons but also enables their rapid extraction and sustains long-lived（> 2 ns） high-energy states. As a proof of concept, the composite photocatalyst achieves near-infrared-lightdriven C（sp3）–S cross-coupling reactions for the first time. This protocol effectively produces over 50 alkylthioethers from a wide scope range of non-active alkyl bromides and chlorides, aryl and alkyl thiols. This work provides a new strategy for highefficiency extraction of hot electrons within plasmonic metal nanostructures and paves the way for hot electron-driven photocatalytic organic transformations.

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CHOLINE TRANSPORTER-RELATED 4(CTR4)Is Involved in Drought and Saline Tolerance in Rice

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Rice science 2025年第1期32卷 52-66,I0041-I0049页

作者： YU Shicong LUO Ruxian ZHENG Shuqin NING jing SHI Yuanzhu GUO Daiming JIA Liangmeng WANG Sen XIAO Guizong GUO Pengwang LI Yang ma Xiaoding State Key Laboratory of Crop Gene Exploration and Utilization in Southwest China Rice Research InstituteSichuan Agricultural UniversityChengdu 611134China State Key Laboratory of Crop Gene Resources and Breeding Institute of Crop SciencesChinese Academy of Agricultural SciencesBeijing 100081China National Crop Genebank Institute of Crop ScienceChinese Academy of Agricultural SciencesBeijing 100081China

The tolerance of rice to drought and saline stress is crucial for maintaining yields and promoting widespread *** an ethyl methanesulfonate(EMS)-mutagenized mutant library,we identified a mutant that is susceptible to osmotic stress,named Osmotic Stress Sensitivity 1(Oss1).Using Mutmap sequencing,we characterized the role of a choline transporter-related family gene,CTR4(Choline Transporter-Related 4),in rice’s tolerance to drought and salt ***4 plays a critical role in regulating membrane lipid *** knockout mutants,the total membrane lipid content,especially unsaturated fatty acids,was significantly *** with the wild type,knockout mutants exhibited decreased membrane lipid stability under drought and salt stress,faster water loss,higher relative electrolyte leakage,and lower levels of proline and soluble sugars,leading to impaired tolerance to drought and salt *** contrast,the overexpression of CTR4 enhanced seedling tolerance to drought and saline *** overexpression lines displayed lower malondialdehyde levels,reduced relative electrolyte leakage,and slower rates of leaf water loss under stress conditions,thereby improving seedling survival rates during ***,lipid synthesis gene expression was down-regulated in CTR4 mutants,potentially exacerbating membrane permeability defects and further compromising stress *** findings suggest that CTR4 mediates choline transport and influences cell membrane formation,thereby enhancing rice defenses against drought and salt stress by maintaining lipid homeostasis.

关键词： Oryza sativa drought stress salt stress choline transporter lipid homeostasis

New chapter in reform and development of organ donation and transplantation in China: Embracing past, grounding in national conditions, upholding steadfast belief, and looking forward to future

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Hepatobiliary & Pancreatic Diseases International 2025年第1期24卷 6-13页

作者： Hong-Tao Zhao Shu-Sen Zheng Jia Fan Jia-Hong Dong Zhong-Hua Chen Wu-Jun Xue Qi-Fa Ye Hai-Bo Wang jing-Yu Chen Zhe Zheng Feng Huo Xiao-Shun He Miao Pu jie Zhao jie-Fu Huang China Organ Transplantation Development Foundation Beijing 100010China China National Human Organ Donation and Transplantation Committee Beijing 100010China The First Affiliated Hospital Zhejiang University School of MedicineHangzhou 310003China Zhongshan Hospital Fudan UniversityShanghai 200032China Beijing Tsinghua Changgung Hospital Affiliated to Tsinghua University Beijing 102218China Tongji Hospital Tongji Medical CollegeHuazhong University of Science&TechnologyWuhan 430014China The First Affiliated Hospital of Xi’an Jiaotong University Xi’an 710061China Zhongnan Hospital of Wuhan University Wuhan 430000China Wuxi People’s Hospital Wuxi 214023China Fuwai Hospital Chinese Academy of Medical SciencesBeijing 100037China General Hospital of Southern Theater Command of PLA Guangzhou 510120China The First Affiliated Hospital of Sun Yat-sen University Guangzhou 510080China

The reform stems from honesty and determination. Since 2005, organ donation and transplantation in China has undergone thorough reform, which complies with legislation requirements and ethical principles established by the World Health Organization(WHO). Reform in China has demonstrated the unwavering confidence and utmost determination of the Chinese government and the Chinese transplantation community. The year 2015 marked a historic turning point when voluntary donations from Chinese citizens became the sole legitimate source for organ transplantation. Since 2015, China has gradually established and refined the “Chinese Mode” and “China System” for organ donation and transplantation, fulfilling its political pledge of reform, and has garnered international recognition, and fostered a social culture which promotes organ donation. This article reviewed the history of reform on organ donation and transplantation in China, presented a new pattern of establishment of organ donation system in the new era of the country, and the direction of advances in the future.

关键词： Reform Legislation Organ donation Organ transplantation Chinese mode High quality development