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A pathophysiology-based approach to the management ot early priapism

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Asian Journal of Andrology 2013年第1期15卷 20-26页

作者： Jason R kovac Siu k mak maurice m Garcia Tom FLue Scott Department of Urology Baylor College of Medicine Houston TX 77030 USA The Chinese University of Hong kong Department of Surgery Prince of Wales HosPital Hong Kong China Department of Urology University of California San Francisco CA 94143 USA

Priapism is a rare condition that involves persistent penile erection for greater than 4 h. Distinct variants exist, each with unique characteristics. Ischemic priapism is a painful medical emergency that may occur as a result of veno-occlusion leading to hypoxia and tissue death. Recurrent bouts of ischemic priapism, or stuttering priapism, require treatment for individual attacks as well as long-term prevention. Non-ischemic priapism is associated with trauma and may be managed conservatively. Recent advances into the pathophysiology of priapism have allowed the development of treatment algorithms that specifically target the mechanisms involved. In this review, we outline the basics of smooth muscle contraction and describe how derangement of these pathways results in priapism. A pathophysiological approach to the treatment of priapism is proposed with duration-based algorithms presented to assist in management.

关键词： algorithm ischemic management priapism T-shunt tunneling

On the Integrability of the Abel and of the Extended Liénard Equations

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Acta mathematicae Applicatae Sinica 2019年第4期35卷 722-736页

作者： man kwong mak Tiberiu HARkO Departamento de Fsica Facultad de Ciencias Naturales Universidad de Atacama Copayapu 485 Copiapo Chile Department of Physics Babes-Bolyai University Kogalniceanu Street Cluj-Napoca 400084 Romania School of Physics Sun Yat-Sen University Guangzhou 510275 China

We present some exact integrability cases of the extended Liénard equation y′′+ f(y)(y′)n +k(y)(y′)m + g(y)y′+ h(y) = 0, with n > 0 and m > 0 arbitrary constants, while f(y), k(y), g(y), and h(y) are arbitrary functions. The solutions are obtained by transforming the equation Liénard equation to an equivalent first kind first order Abel type equation given bydv/dy= f(y)v3-n+ k(y)v3-m+ g(y)v2+ h(y)v3, with v = 1/y′.As a first step in our study we obtain three integrability cases of the extended quadratic-cubic Liénard equation,corresponding to n = 2 and m = 3, by assuming that particular solutions of the associated Abel equation are known. Under this assumption the general solutions of the Abel and Liénard equations with coefficients satisfying some differential conditions can be obtained in an exact closed form. With the use of the Chiellini integrability condition, we show that if a particular solution of the Abel equation is known, the general solution of the extended quadratic cubic Liénard equation can be obtained by quadratures. The Chiellini integrability condition is extended to generalized Abel equations with g(y) ≡ 0 and h(y) ≡ 0, and arbitrary n and m, thus allowing to obtain the general solution of the corresponding Liénard equation. The application of the generalized Chiellini condition to the case of the reduced Riccati equation is also considered.

关键词： Abel equation Liénard equation general solutions integrability conditions

Removal of Lead from Aqueous Solution by Acinetobacter calcoaceticus

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Biomedical and Environmental Sciences 1990年第2期3卷 202-210页

作者： N.k.mak Y.k.mOk V.W.D.CHUI m.H.WONG Department of Biology Hong Kong Baptist College 224 Waterloo Road Hong Kong

A bacterial strain tolerant to the presence of 400 ppm lead was isolated from digested sewage sludge. The organism was identified as Acinetobacter calcoaceticus var: anitraus (98% confidence). Both viable and formalin-inactivated bacterial cells could remove Pb from an aqueous solution. The Pb-binding ability of inactivated cells was compared with that of a commercial ion-exchange resin, Amberlite IR-I20. The metal-binding ability of A. calcoaceticus followed the sequence Pb≥Cu≥Cr≥ (Cd, Ni, and Zn)≥Co. The ability of the inactivated cells to remove Pb was pH sensitive, and the adsorption process was slightly affected at high temperature (70℃). The adsorption and desorption process worked equally well with A. calcoaceticus embedded in a polyacrylamide gel matrix. (c)1990 Academic Press, Inc.

关键词：柳人

Continuity Adjustment for Control Charts for Attributes

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Acta mathematicae Applicatae Sinica 2003年第3期19卷 397-404页

作者： L.k.Chan T.k.mak B.Tao Department of management Sciences City University of Hong Kong 83 Tat Chee AvenueKowloonHong KongDepartment of Decision Sciences & M.I.S.Concordia University 1445 De Maisonneuve Blvd.WestMontrealH3G 1M8 CanadaAcademy of Mathematics and System SciencesChinese Academy of SciencesBeijing 100081China

A unified approach is proposed for making a continuity adjustment on some control charts for attributes, e.g., np-chart and c-chart, through adding a uniform (0, 1) random observation to the conventional sample statistic (e.g., and c i ). The adjusted sample statistic then has a continuous distribution. Consequently, given any Type I risk α (the probability that the sample statistic is on or beyond the control limits), control charts achieving the exact value of α can be readily constructed. Guidelines are given for when to use the continuity adjustment control chart, the conventional Shewhart control chart (with ±3 standard deviations control limits), and the control chart based on the exact distribution of the sample statistic before adjustment.

关键词： Control charts for attributes continuity adjustments np, p, and c control charts statistical process control

mapping nanoscale topographic features in thick tissues with speckle diffraction tomography

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Light(Science & Applications) 2023年第9期12卷 1877-1885页

作者： Sungsam kang Renjie Zhou marten Brelen Heather k.mak Yuechuan Lin Peter T.C.So Zahid Yaqoob Laser Biomedical Research Center G.R.Harrison Spectroscopy LaboratoryMassachusetts Institute of TechnologyCambridgeMA 02139USA Department of Biomedical Engineering The Chinese University of Hong KongHong KongChina Department of Ophthalmology and Visual Sciences The Chinese University of Hong KongHong KongChina Department of mechanical Engineering Massachusetts Institute of TechnologyCambridgeMA 02139USA Department of Biological Engineering Massachusetts Institute of TechnologyCambridgeMA 02139USA Department of Biomedical Engineering Boston UniversityBostonMA 02215USA

Resolving three-dimensional morphological features in thick specimens remains a significant challenge for label-free *** report a new speckle diffraction tomography(SDT)approach that can image thick biological specimens with~500 nm lateral resolution and~1μm axial resolution in a reflection *** SDT,multiple-scattering background is rejected through spatiotemporal gating provided by dynamic speckle-field interferometry,while depth-resolved refractive index maps are reconstructed by developing a comprehensive inverse-scattering model that also considers specimen-induced *** from the high-resolution and full-field quantitative imaging capabilities of SDT,we successfully imaged red blood cells and quantified their membrane fluctuations behind a turbid medium with a thickness of 2.8 scattering mean-free *** importantly,we performed volumetric imaging of cornea inside an ex vivo rat eye and quantified its optical properties,including the mapping of nanoscale topographic features of Dua’s and Descemet’s membranes that had not been previously visualized.

关键词： speckle inverse interferometry

On Identitiesand m-Neutral Sequencesof n-Ary Groups

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Communications in mathematics and Statistics 2016年第4期4卷 495-508页

作者： Alexander m.Gal’mak Viktoria A.kovaleva Department of Technology Mogilev State University of Food Technologies212027 MogilevBelarus Department of mathematics Francisk Skorina Gomel State University246019 GomelBelarus

In this paper,we study such polyadic analog of an identity of a group asm-neutral *** particular,we prove that all Post's equivalence classes of thefree covering group of any n-ary group[where n=k(m-1)+1 and k≥1]definedby m-neutral sequences form the(k+1)-ary group,which is isomorphic to the n-arysubgroup of all identities of the n-ary group in the case when m=2.

关键词： n-Ary group Identity m-Neutral sequence

Detection of HIV-1 antigen based on magnetic tunnel junction sensors

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Chinese Physics B 2020年第8期29卷 538-542页

作者： Li Li kai-Yu mak Yan Zhou School of Science and Engineering The Chinese University of Hong KongShenzhen 518172China Hefei National Laboratory for Physical Sciences at the microscale Department of PhysicsUniversity of Science and Technology of ChinaHefei 230026China

We report a p24(HIV disease biomarker)detection assay using an mgO-based magnetic tunnel junction(mTJ)sensor and 20-nm magnetic *** mTJ array sensor with sensing area of 890×890μ2 possessing a sensitivity of 1.39%/Oe was used to detect p24 *** is demonstrated that the p24 antigens could be detected at a concentration of 0.01μg/*** development of bio-detection systems based on magnetic tunnel junction sensors with high-sensitivity will greatly benefit the early diagnosis of HIV.

关键词： mgO-based magnetic tunnel junction sensor HIV bio-detection system antigen p24 early disease diagnosis

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屋顶振源室内低频耦合响应场有限元研究

哈尔滨工业大学学报 2004年第3期36卷 338-343页

作者：姜根山安连锁 C.m.mak 华北电力大学应用物理系河北保定071003 香港理工大学屋宇设备工程学系

利用有限元方法计算了低频激发力作用下屋顶振源在室内产生振动耦合响应场的空间分布及其频率响应特征;指出了薄壁矩形封闭空间与刚性壁空间的模态频率存在一定偏差,并且在模态频率较高时偏差比较大.在激发力频率接近房间结构的共振频... 详细信息

利用有限元方法计算了低频激发力作用下屋顶振源在室内产生振动耦合响应场的空间分布及其频率响应特征;指出了薄壁矩形封闭空间与刚性壁空间的模态频率存在一定偏差,并且在模态频率较高时偏差比较大.在激发力频率接近房间结构的共振频率或腔内声模态频率时,室内耦合声场将获得较大声压级,特别是当结构共振频率与腔内模态频率发生重叠时,以该频率激发结构会使室内耦合响应场的声压级得到极大加强,因此,在设计建筑物时应当避免共振频率与模态频率的重叠.通过分别计算在非特征(共振或模态)频率(80 Hz)与特征(共振和模态重叠)频率(116 Hz)激发力作用下的各壁声压级及其结构位移振幅分布,给出了各壁面在相应激发力作用下向室内辐射声能量的相对贡献,指出对室内声能量贡献起主要作用的有时不一定是屋顶,而可能是侧面墙壁.

关键词：结构振动耦合声场激发力频率响应有限元方法屋顶振源建筑物

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对故障敏感的负荷节点和关键节点的辨识

电力系统自动化 2004年第13期18卷 39-44页

作者：林济铿罗萍萍曹绍杰 C.m.mak k.m.Yung 天津大学电气与自动化工程学院天津市300072 上海电力学院上海市200090 香港城市大学香港中华电力公司

电力系统中许多大扰动都会导致系统负荷降低。对于系统调度员来说,了解和掌握系统中是否存在一些受故障扰动影响而负荷降低始终是最严重的节点、变电站,是相当有用的,同时也是一个具有挑战性的工作。文中将数据挖掘技术用于识别香港电... 详细信息

电力系统中许多大扰动都会导致系统负荷降低。对于系统调度员来说,了解和掌握系统中是否存在一些受故障扰动影响而负荷降低始终是最严重的节点、变电站,是相当有用的,同时也是一个具有挑战性的工作。文中将数据挖掘技术用于识别香港电力系统中与故障相关的最敏感的变电站。定义了量度负荷降低严重性程度的两个指标。基于数据统计分析找到了对故障扰动最敏感的变电站,其正确性得到了实际电力系统专家的证实。此外,通过对电压曲线的相关分析,找出了系统中的关键节点,对这些节点实施有效的电压调节,将有助于故障后敏感节点电压的恢复。

关键词：数据挖掘负荷降低敏感节点增强电压恢复