Detection of HIV-1 antigen based on magnetic tunnel junction sensors

作     者：Li Li Kai-Yu Mak Yan Zhou 李丽;麦启宇;周艳

作者机构：School of Science and EngineeringThe Chinese University of Hong KongShenzhen 518172China Hefei National Laboratory for Physical Sciences at the MicroscaleDepartment of PhysicsUniversity of Science and Technology of ChinaHefei 230026China 

出 版 物：《Chinese Physics B》 (中国物理B（英文版）)

年 卷 期：2020年第29卷第8期

页      面：538-542页

核心收录：

学科分类：1004[医学-公共卫生与预防医学(可授医学、理学学位)] 080202[工学-机械电子工程] 08[工学] 100401[医学-流行病与卫生统计学] 0802[工学-机械工程] 10[医学] 

基　　金：President’s Fund of CUHKSZ,Longgang Key Laboratory of Applied Spintronics,at The Chinese University of Hong Kong,the National Natural Science Foundation of China(Grant Nos.11974298 and 61961136006) the Shenzhen Fundamental Research Fund,China(Grant No.JCYJ20170410171958839) Shenzhen Peacock Group Plan,China(Grant No.KQTD20180413181702403) 

主　　题：MgO-based magnetic tunnel junction sensor HIV bio-detection system antigen p24 early disease diagnosis 

摘      要：We report a p24(HIV disease biomarker)detection assay using an MgO-based magnetic tunnel junction(MTJ)sensor and 20-nm magnetic *** MTJ array sensor with sensing area of 890×890μ2 possessing a sensitivity of 1.39%/Oe was used to detect p24 *** is demonstrated that the p24 antigens could be detected at a concentration of 0.01μg/*** development of bio-detection systems based on magnetic tunnel junction sensors with high-sensitivity will greatly benefit the early diagnosis of HIV.