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Coverless Image steganography Based on Jigsaw Puzzle Image Generation

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Computers, materials & Continua 2021年第5期67卷 2077-2091页

作者： Al Hussien seddik saad m.s.mohamed E.H.Hafez Department of Computer science Faculty of ScienceMinia UniversityMinya61519Egypt Department of mathematics College of ScienceTaif UniversityTaif21944Saudi Arabia Department of mathematics Faculty of ScienceAl-Azher UniversityNasr City11884Egypt Department of mathematics Faculty of ScienceHelwan UniversityCairoEgypt

Current image steganography methods are working by assigning an image as a cover file then embed the payload within it by modifying its pixels,creating the stego ***,the left traces that are caused by these modifications will make steganalysis algorithms easily detect the hidden payload.A coverless data hiding concept is proposed to solve this *** does not mean that cover is not required,or the payload can be transmitted without a ***,the payload is embedded by cover generation or a secret message mapping between the cover file and the *** this paper,a new coverless image steganography method has been proposed based on the jigsaw puzzle image generation driven by a secret ***,the image is divided into equal rows then further divided into equal columns,creating blocks(i.e.,sub-images).Then,according to secret message bits and a proposed mapping function,each block will have tabs/blanks to get the shape of a puzzle piece creating a fully shaped jigsaw puzzle *** that,the generated jigsaw puzzle image is sent to the *** results and analysis show a good performance in the hiding capacity,security,and robustness compared with existing coverless image steganography methods.

关键词： Coverless information hiding Jigsaw puzzle image image steganography data hiding

Paraconductivity study in ErBa_2Cu_(3-x)m_xO_(7-δ)(m=Zn, Fe) superconductors

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Chinese Physics B 2013年第11期22卷 562-568页

作者： A.sedky s.B.mohamed Physics Department Faculty of Science King Faisal University Physics Department Faculty of Science Assiut University

We report here the paraconductivity of ErBa2Cu3-xmxO7-δ （m = Zn and Fe） superconductors. The logarithmic plots of excess conductivity Δσ and reduced temperature C reveal two different exponents corresponding to crossover temperature as a result of shifting the order parameter from 2 to 3. The first exponent in the normal field region is close to 1, in which the order parameter dimensionality （OPD） is 2. The second exponent in the critical field region is close to 0.5, in which the OPD is 3. The coherence length, interlayer coupling, interlayer separation and carrier concentration decrease with increasing doping content, and their values for Fe samples are different from those of Zn samples. While anisotropy is increased with increasing doping content, it is generally higher for a Zn sample than that for an Fe sample. We also estimate several physical parameters such as upper critical magnetic fields in the a–b plane and along the c axis （Bab and Bc）, and critical current density J at 0 K. Although Bab and Bc are generally increased with doping content increasing, the value of Bab is found to be twice more than that of Bc. A similar behavior is obtained for J （0 K） and its value is higher in the Fe sample than that in the Zn sample. These results are discussed in terms of oxygen deficiency, localization of carriers, and flux pinning, which are produced by doping.

关键词： ceramics chemical synthesis X-ray diffraction electrical properties transport properties

Impact of Zika virus non-structural protein mutations on hippocampal damage

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Neural Regeneration Research 2025年第8期20卷 2307-2308页

作者： Larissa m.G.Cassiano Roney s.Coimbra Neurogenômica/Imunopatologia Instituto RenéRachouFiocruzBelo HorizonteBrazil Departamento de Bioquímica e Imunologia Instituto de Ciências BiológicasUniversidade Federal de Minas GeraisBelo HorizonteBrazil

The Zika virus(ZIKV),a member of the Flaviviridae family,attracted worldwide attention for its connection to severe neurological effects,notably microcephaly in newborns,first reported during the 2015 epidemic in ***,its impact goes beyond fetal and neonatal abnormalities,also affecting the central nervous system(CNs)in both children and adults,leading to enduring cognitive and behavioral impairments.

关键词： damage fetal neonatal

Gut virome:New key players in the pathogenesis of inflammatory bowel disease

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World Journal of methodology 2025年第2期15卷 27-43页

作者： Helal F Hetta Rehab Ahmed Yasmin N Ramadan Hayam Fathy mohammed Khorshid mohamed m mabrouk mai Hashem Department of medical microbiology and Immunology Faculty of MedicineAssiut UniversityAssiut 71515Egypt Division of microbiology Immunology and BiotechnologyFaculty of pharmacyUniversity of TabukTabuk 71491Saudi Arabia Division of microbiology Immunology and BiotechnologyDepartment of Natural Products and Alternative MedicineFaculty of PharmacyUniversity of TabukTabuk 71491Saudi Arabia Department of Internal medicine Division HepatogastroenterologyAssiut UniversityAssiut 71515Egypt Department of Clinical Research Egyptian Developers of Gastroenterology and Endoscopy FoundationCairo 11936Egypt Department of Internal medicine Faculty of Medicine.Tanta UniversityTanta 31527Egypt Department of Tropical medicine Gastroenterology and HepatologyAssiut University HospitalAssiut 71515Egypt

Inflammatory bowel disease(IBD)is a chronic inflammatory illness of the *** the mechanism underlying the pathogenesis of IBD is not fully under-stood,it is believed that a complex combination of host immunological response,environmental exposure,particularly the gut microbiota,and genetic suscept-ibility represents the major *** gut virome is a group of viruses found in great frequency in the gastrointestinal tract of *** gut virome varies greatly among individuals and is influenced by factors including lifestyle,diet,health and disease conditions,geography,and *** majority of research has focused on the significance of gut bacteria in the progression of IBD,although viral populations represent an important component of the *** conducted this review to highlight the viral communities in the gut and their expected roles in the etiopathogenesis of IBD regarding published research to date.

关键词： Inflammatory bowel disease Pathogenesis Gut virome Bacteriophage Eukaryotic viruses

m2BPGi for assessing liver fibrosis in patients with hepatitis C treated with direct-acting antivirals

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World Journal of Gastroenterology 2020年第21期26卷 2864-2876页

作者： shereen A saleh mohamed m salama marwan m Alhusseini Ghada A mohamed Gastroenterology and Hepatology Unit Department of Internal MedicineFaculty of MedicineAin Shams UniversityCairo 11341Egypt

BACKGROUND Assessing liver fibrosis is important for predicting the efficacy of direct-acting antivirals(DAAs)and patient ***-invasive techniques to assess liver fibrosis are becoming ***,serum mac-2 binding protein glycosylation isomer(m2BPGi)was identified as a non-invasive marker of liver *** To investigate the diagnostic accuracy of m2BPGi in assessing liver fibrosis in patients with chronic hepatitis C(CHC)treated with *** From December 2017 to August 2018,80 treatment-naive adult patients with CHC who were eligible for DAAs therapy were consecutively enrolled in this observational cohort *** 12 weeks,65 patients were treated with sofosbuvir/daclatasvir,and 15 patients were treated with sofosbuvir/daclatasvir and a weight-based dose of ribavirin at knowledge and technology association for hepatitis C management clinic,Cairo,*** measured serum m2BPGi levels,PAPAs index,fibrosis-4(FIB-4)score and liver stiffness measurements(Lsm)at baseline and 12 weeks after the end of *** m2BPGi levels were measured using enzyme-linked immunosorbent *** All patients achieved sustained virologic response(sVR12)(100%).serum m2BPGi levels,Lsm,FIB-4 score and PAPAs index decreased significantly at sVR12(Pserum m2BPGi levels correlated positively with Lsm at baseline and sVR12(Pseline,compared with the FIB-4 score and PAPAs index,m2BPGi was the best marker to distinguish patients with grade F4 fibrosis(AUC=0.801,Ps with grade F2 from grade F0-1 fibrosis(AUC=0.713,P=0.012),patients with grade F3-4 from grade F0-2 fibrosis(AUC=0.730,Ps with grade F2-4 from grade F0-1 fibrosis(AUC=0.763,PsVR12,m2BPGi had the greatest AUCs for differentiating patients with grade F4 fibrosis(AUC=0.844,Ps with grade F3 from grade F0-2 fibrosis(AUC=0.893,P=0.002),patients with grade F3-4 from grade F0-2 fibrosis(AUC=0.891,Ps with grad

关键词： Hepatitis C virus Liver fibrosis Human mac-2 binding protein Antiviral agents sustained virologic response Elastography

Optimal and memristor-Based Control of A Nonlinear Fractional Tumor-Immune model

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Computers, materials & Continua 2021年第6期67卷 3463-3486页

作者： Amr m.s.mahdy mahmoud Higazy mohamed s.mohamed Department of mathematics College of ScienceTaif UniversityTaif21944Saudi Arabia Department of mathematics Faculty of ScienceZagazig UniversityZagazig44519Egypt Department of Physics and Engineering mathematics Faculty of Electronic engineeringMenoufia UniversityMenouf32952Egypt Department of mathematics Faculty of ScienceAl-Azher UniversityNasr City11884Egypt

In this article,the reduced differential transform method is introduced to solve the nonlinear fractional model of *** fractional derivatives are described in the Caputo *** solutions derived using this method are easy and very *** model is given by its signal flow ***,a simulation of the system by the simulink of mATLAB is *** disease-free equilibrium and stability of the equilibrium point are *** of a fractional optimal control for the cancer model is *** addition,to control the system,we propose a novel modification of its *** modification is based on converting the model to a memristive one,which is a first time in the literature that such idea is used to control this type of ***,we study the system’s stability via the Lyapunov exponents and Poincare maps before and after *** order differential equations(FDEs)are commonly utilized to model systems that have memory,and exist in several physical phenomena,models in thermoelasticity field,and biological *** have been utilized to model the realistic biphasic decline manner of elastic systems and infection of diseases with a slower rate of *** are more useful than integer-order in modeling sophisticated models that contain physical phenomena.

关键词： RDTm tumor-immune optimal control caputo derivative signal flow simulink disease-free equilibrium stability memristive lyapunov exponents poincare map

Antioxidant Effect of sepia Ink Extract on Extrahepatic Cholestasis Induced by Bile Duct Ligation in Rats

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Biomedical and Environmental sciences 2015年第8期28卷 582-594页

作者： Hanan saleh Amel m soliman Ayman s mohamed mohamed-Assem s marie Zoology Department Faculty of Science Cairo University

Objective The aim of our study was to assess the complications of hepatic fibrosis associated with bile duct ligation and the potential curative role of sepia ink extract in hepatic damage induced by bile duct ligation. methods Rattus norvegicus rats were divided into 3 groups: sham-operated group, model rats that underwent common bile duct ligation (BDL), and BDL rats treated orally with sepia ink extract (200 mg/kg body weight) for 7, 14, and 28 d after BDL. Results There was a significant reduction in hepatic enzymes, ALP, GGT, bilirubin levels, and oxidative stress in the BDL group after treatment with sepia ink extract. Collagen deposition reduced after sepia ink extract treatment as compared to BDL groups, suggesting that the liver was repaired. Histopathological examination of liver treated with sepia ink extract showed moderate degeneration in the hepatic architecture and mild degeneration in hepatocytes as compared to BDL groups. Conclusion sepia ink extract provides a curative effect and an antioxidant capacity on BDL rats and could ameliorate the complications of liver cholestasis.

关键词： Bile duct ligation Hepatic fibrosis Oxidative stress Liver collagen percentage Histopathological examination

Brain-derived neurotrophic factor signaling in the neuromuscular junction during developmental axonal competition and synapse elimination

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Neural Regeneration Research 2025年第2期20卷 394-401页

作者： Josep Tomàs Víctor Cilleros-mañé Laia Just-Borràs marta Balanyà-segura Aleksandra Polishchuk Laura Nadal marta Tomàs Carolina silvera-simón manel m.santafé maria A.Lanuza Unitat d’Histologia i Neurobiologia(UHNeurob) Facultat de Medicina i Ciències de la SalutUniversitat Rovira i VirgiliReusSpain

During the development of the nervous system,there is an overproduction of neurons and *** competition between neighboring nerve endings and synapses performing different activity levels leads to their elimination or *** have extensively studied the involvement of the brain-derived neurotrophic factor-Tropomyosin-related kinase B receptor neurotrophic retrograde pathway,at the neuromuscular junction,in the axonal development and synapse elimination process versus the synapse *** purpose of this review is to describe the neurotrophic influence on developmental synapse elimination,in relation to other molecular pathways that we and others have found to regulate this *** particular,we summarize our published results based on transmitter release analysis and axonal counts to show the different involvement of the presynaptic acetylcholine muscarinic autoreceptors,coupled to downstream serine-threonine protein kinases A and C(PKA and PKC)and voltage-gated calcium channels,at different nerve endings in developmental *** dynamic changes that occur simultaneously in several nerve terminals and synapses converge across a postsynaptic site,influence each other,and require careful studies to individualize the mechanisms of specific *** describe an activity-dependent balance(related to the extent of transmitter release)between the presynaptic muscarinic subtypes and the neurotrophin-mediated TrkB/p75NTR pathways that can influence the timing and fate of the competitive interactions between the different axon *** downstream displacement of the PKA/PKC activity ratio to lower values,both in competing nerve terminals and at postsynaptic sites,plays a relevant role in controlling the elimination of supernumerary ***,calcium entry through L-and P/Q-subtypes of voltage-gated calcium channels(both channels are present,together with the N-type channel in developing nerve terminals)contributes to red

关键词： acetylcholine release adenosine receptors axonal competition brain-derived neurotrophic factor calcium channels motor end-plate muscarinic acetylcholine receptors postnatal synapse elimination serine kinases tropomyosin-related kinase receptorB

Development of new potentiometric sensors for the determination of proguanil hydrochloride in serum and urine

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Chinese Chemical Letters 2016年第6期27卷 857-863页

作者： Fatehy m.Abdel-Haleem mohamed saad mohamed s.Rizk Chemistry Department Faculty of Science Cairo University

Potentiometric electrodes were developed for the rapid determination of proguanil hydrochloride in pure samples, pharmaceutical preparations and spiked serum and urine samples using PVC membrane,screen printed（sPE）, coated wired（CWE）, carbon paste（CPE） and modified carbon paste（mCPE）electrodes based on the ion-exchanger of proguanil with phosphotungestic acid（Pr-PT） as a chemical modifier. The prepared electrodes showed Nernestian slopes of 59.7, 58.1, 58.5, 58.5 and 57.0 for the PVC,sPE, CWE, CPE and mCPE for the proguanil ions in a wide concentration range of 1.0 ＊ 10^-5–1.0 ＊ 10^-2mol L^-1 at 25°C with detection limits of 7.94 ＊ 10^-6, 1.0 ＊ 10^-5, 1.0 ＊ 10^-6, 7.07 ＊ 10^-6 and 2.5 ＊ 10^-6 mol L^-1, respectively. The prepared electrodes exhibited high proguanil selectivity in relation to several inorganic ions and sugars and they could be successfully utilized for its determination in pure solutions, pharmaceutical preparations and serum and urine samples using the direct potentiometry and standard addition methods with very good recovery values.

关键词： Proguanil hydrochloride PVC membrane electrode Carbon paste electrode screen printed electrode mWCNTs Coated wire electrode